Developing disease-resistant, high-quality improved crop varieties to benefit agricultural producers and consumers may seem like a “hairy” task, but Texas A&M AgriLife Research scientists may have gotten to the root of the issue.
BACKGROUNDScar formation and loss of cutaneous appendages are the greatest challenges in cutaneous wound healing. Previous studies have indicated that antler reserve mesenchyme (RM) cells and their conditioned medium improved regenerative w
BACKGROUNDZinc (Zn) is the second most abundant trace element after Fe, present in the human body. It is frequently reported in association with cell growth and proliferation, and its deficiency is considered to be a major disease contribut
BACKGROUNDHaploid embryonic stem cells (haESCs) have been established in many species. Differentiated haploid cell line types in mammals are lacking due to spontaneous diploidization during differentiation that compromises lineage-specific
BACKGROUNDCurrent evidence shows that human induced pluripotent stem cells (hiPSCs) can effectively differentiate into keratinocytes (KCs), but its effect on skin burn healing has not been reported. AIMTo observe the effects of hiPSCs-deri
BACKGROUNDMesenchymal stromal cells (MSCs) are multipotent cell populations obtained from fetal and adult tissues. They share some characteristics with limb bud mesodermal cells such as differentiation potential into osteogenic, chondrogeni
Parkinson’s disease (PD), characterized by loss of nigrostriatal dopaminergic neurons, is one of the most predominant neurodegenerative diseases affecting the elderly population worldwide. The concept of stem cell therapy in managing neur
In recent years, mesenchymal stem cells (MSC) have been considered the most effective source for regenerative medicine, especially due to released soluble paracrine bioactive components and extracellular vesicles. These factors, collectivel
Acute pancreatitis (AP) often leads to a high incidence of cardiac injury, posing significant challenges in the treatment of severe AP and contributing to increased mortality rates. Mesenchymal stem cells (MSCs) release bioactive molecules
Scientists have unraveled the step-by-step activation process of a protein with a deep evolutionary history in all domains of life, opening the door to harnessing its functions for use as a biotechnology tool.
PBD Biotech developers of Actiphage TB, a ground-breaking phage-based diagnostic for laboratory tuberculosis testing, has today announced it has secured the grant of a US patent for its diagnostic kit. The company is exhibiting in the AACC Clinical Lab Expo on booth #4578.
Researchers have created a unique microscopic toolkit of ‘green’ tuneable electrical components, paving the way for a new generation of bioelectronic devices and sensors.
A new study describes how a novel nanomaterial can treat disorders of toxic levels of hydrogen sulfide that occur in Down syndrome and many other disorders.
Base editing technology invented at Rutgers, The State University of New Jersey, and exclusively licensed to Revvity, Inc. subsidiary Horizon Discovery, has been sub-licensed to biopharmaceutical company AstraZeneca to support its creation of cell therapies for the treatment of cancer and immune-mediated diseases.
Scientists from The Federal Research Centre “Fundamentals of Biotechnology” of the Russian Academy of Sciences (Research Center of Biotechnology RAS) elaborated mathematical algorithm that enabled to find dispersed repeated elements in genome with great accuracy.
Drawing inspiration from natural sensory systems, an MIT-led team has designed a novel sensor that could detect the same molecules that naturally occurring cell receptors can identify.
Microbes have enormous potential to produce metabolites with potential industrial applications. To do so, microbes use groups of genes called biosynthetic gene clusters (BGCs) that code for the sets of necessary enzymes. Scientists have computationally predicted the products of hundreds of thousands of BGCs, but have experimentally confirmed fewer than 2,000 of them. Researchers have now developed a computational and experimental strategy to redesign BGCs and determine the natural chemical products they create.
Microbial communities are widely used biotechnology suppliers for processes like manufacturing biofuels and new foods, or helping crops grow better.
Scientists from Research Center of Biotechnology RAS with colleagues developed a set of plasmids that deliver CRISPR-Cas9 component genes into cells in the form of individual DNA molecules that are combined into a single genetic construct directly in yeast.
In the next step toward producing the answer to kidney transplantation shortages, Dr. Anthony Atala, Director of the Wake Forest Institute for Regenerative Medicine (WFIRM), and the kidney research team, have been awarded the prestigious KidneyX Track 2 $1 Million Prize for work based on a 3D kidney construct platform.
Although early detection of osteoporosis could help physicians intervene as soon as possible, this type of detection is not yet possible with current diagnostic tests. Now researchers reporting in ACS Central Science have developed a biosensor that could help identify those at risk for osteoporosis.
Illumina Inc., a global leader in DNA sequencing and array-based technologies, in collaboration with Nashville Biosciences LLC, a leading clinical and genomic data company and wholly owned subsidiary of Vanderbilt University Medical Center, today announced the five founding new members of the Alliance for Genomic Discovery (AGD).
Halo Labs, a pioneer in life science instrumentation, announced the launch of its new Aura®+ Subscription Program.
Urotronic, Inc., a Minnesota-based medical device company pioneering the application of its drug-coated balloon technologies for use in interventional urology, today announced the world's first commercial procedure of the Optilume BPH® Catheter System to treat benign prostatic hyperplasia (BPH) was completed by Dr. Dean Elterman, urologist at University Urology Associates, in Toronto, Canada.
CEPI to provide up to $4.98 USD million to Houston Methodist Research Institute-led consortium to use artificial intelligence for design of vaccines to fight diseases with pandemic potential. The project will support a consortium, led by HMRI, to design potential antigenic targets for up to 10 priority virus families with epidemic or pandemic potential. Laboratory-based tests will then be used to verify antigen designs for possible further development.
Rakuten Medical, Inc. (Rakuten Medical), a global biotechnology company developing and commercializing precision, cell-targeting photoimmunotherapy-based on its proprietary Alluminox™ platform, today announced it will host a virtual R&D Day on the preliminary safety and efficacy findings from its open-label Phase 1b/2 study of Alluminox™ treatment using ASP-1929 in combination with anti-PD-1 therapy in recurrent and/or metastatic head and neck squamous cell carcinoma (HNSCC).
Rensselaer Polytechnic Institute’s Catherine Royer, Constellation Chair Professor of Bioinformatics and Biocomputation at the Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS) and professor of biological sciences, has received a grant of over $400,000 from the National Science Foundation to investigate enzymes from organisms living in deep sea environments.
PNNL’s wide-ranging report maps the current nanobiotechnology landscape, flags potential concerns, and details the need for an organizing body to coordinate currently disparate disciplines.
The Cedars-Sinai Accelerator is welcoming 10 health-tech companies from around the world to its ninth accelerator class. The businesses are building a variety of healthcare solutions—from monitoring devices for sepsis, heart failure and stroke, to virtual reality video games aimed at helping children manage pain and anxiety during medical procedures.
Urotronic, Inc. today announced it has received U.S. Food and Drug Administration (FDA) approval of its Optilume® BPH Catheter System, a unique minimally invasive surgical therapy (MIST) that combines mechanical dilation using a proprietary double-lobe balloon with concurrent localized delivery of paclitaxel for the treatment of lower urinary tract symptoms (LUTS) secondary to BPH.
Through joint research with the Korea Institute of Machinery and Materials(KIMM), the Korea Research Institute of Bioscience and Biotechnology (KRIBB) developed a 3D bioprinting technology using natural killer cells (NK cells) as a new method of immunotherapy for treating cancer.
Columbia Engineering researchers announced today that they have developed the first stand-alone, conformable, fully organic bioelectronic device that can not only acquire and transmit neurophysiologic brain signals, but can also provide power for device operation.
EMSL user Marcus Foston is using synthetic biology to create an underwater hydrogel that mimics the strength of mussel foot proteins. Foston explains how this hydrogel’s powerful adhesive could replace surgical sutures and fix cracked boats.
The peptide-guided treatment builds new mineral microlayers that penetrate deep into the tooth to create effective, long-lasting natural protection. The ultimate goal is to provide easily accessible relief for the millions of adults worldwide who suffer from tooth sensitivity.
A team led by researchers at the University of Washington has developed new bioplastics that degrade on the same timescale as a banana peel in a backyard compost bin.
Now that the emergency phase of the COVID-19 pandemic has ended, scientists are looking at ways to surveil indoor environments in real time for viruses. By combining recent advances in aerosol sampling technology and an ultrasensitive biosensing technique, researchers at Washington University in St. Louis have created a real-time monitor that can detect any of the SARS-CoV-2 virus variants in a room in about 5 minutes.
Many at-risk forest tree species will probably need biotechnology along with traditional tree-breeding approaches to survive, according to insights published in the July issue of the journal New Forests.
This fully wireless ultrasound patch, which can capture detailed medical information and wirelessly transmit the data to a smart device, could represent a major step forward in at-home health care technology.
The remarkable level of miniaturization possible in modern electronics has paved the way for realizing healthcare devices previously confined to the realm of science fiction.
Nearly 700,000 people in the United States die from heart disease every year, and one-third of those deaths result from complications in the first weeks or months following a traumatic heart-related event. To help prevent those deaths, researchers at Northwestern and George Washington (GW) universities have developed a new device to monitor and treat heart disease and dysfunction in the days, weeks or months following such events.
Conventional ways of administering medication – by swallowing tablets, consuming bitter syrups, injections or rectal insertions – could be distressing and unpleasant for some patients, especially young children or the elderly. A team of researchers led by Associate Professor Chan Sui Yung, Honorary Fellow at the Department of Pharmacy under the Faculty of Science at the National University of Singapore (NUS), has recently developed easy-to-use oral films that enable painless, efficient, and discreet drug administration.
The study by researchers at New York University, Columbia Engineering, and the New York Genome Center, combines a deep learning model with CRISPR screens to control the expression of human genes in different ways—such as flicking a light switch to shut them off completely or by using a dimmer knob to partially turn down their activity. These precise gene controls could be used to develop new CRISPR-based therapies.
Physicists from the National University of Singapore (NUS) have developed an innovative method of converting human hair waste into a functional material that can be used to encrypt sensitive information or detect environmental pollutants.
A roundup of the latest medical discoveries and faculty news at Cedars-Sinai for June 2023.
Rakuten Medical, Inc., a global biotechnology company developing and commercializing precision, cell targeting therapies based on its proprietary Alluminox™ platform, today announced that new interim evaluation data from the ASP-1929-103 study has been presented at the Society of Nuclear Medicine and Molecular Imaging (SNMMI) 2023 Annual Meeting held from June 24 to 27.
To help people with visual impairments gain more independence, Cal State Fullerton computer engineering students developed assistive glasses, a hands-free wearable technology device. The glasses can help people with visual impairments detect and identify often-used objects — something a guide dog cannot always do.
The June special issue of SLAS Technology showcases the latest developments in the field of biotechnology with its collection of seven research articles.
A multi-faceted device for effectively treating deep, non-compressible, and irregularly-shaped wounds has been engineered by the scientists at the Terasaki Institute for Biomedical Innovation (TIBI).
As we move into a world where human-machine interactions are becoming more prominent, pressure sensors that are able to analyze and simulate human touch are likely to grow in demand. One challenge facing engineers is the difficulty in making the kind of cost-effective, highly sensitive sensor necessary for applications such as detecting subtle pulses, operating robotic limbs, and creating ultrahigh-resolution scales. However, a team of researchers has developed a sensor capable of performing all of those tasks.
Using nanomagnets composites and conductive yarn, scientists have invented a smart textile that can sense and measure body movements—from muscles flexing to veins pulsing.
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