300… and Counting! Children's Hospital Los Angeles Performs Milestone Liver Transplant

Father donates liver tissue to save son's life, and the family gets a visit from CHLA's first-ever living donor liver patient, now all grown up

Article ID: 667030

Released: 29-Dec-2016 7:05 PM EST

Source Newsroom: Childrens Hospital Los Angeles

  • Credit: Children's Hospital Los Angeles

    Top: Lydia Hand as an infant post-transplant in 1998, with her mother, grandmother and liver transplant team. Bottom: Baby Donovan Daniels and his parents post-transplant in 2016, joined by doctors and Lydia, now 18.

  • Credit: Children's Hospital Los Angeles

    Dejon Daniels sees his son Donovan for the first time since the transplant.

Newswise — LOS ANGELES – At 7 months old, Donovan Daniels of Westminster may not understand for some time just how serious his medical condition, biliary atresia, really is. It may be years before he knows he was the 300th pediatric liver transplant ever performed by doctors at Children's Hospital Los Angeles and Keck Medicine of University of Southern California. But one day he'll know his father Dejon Daniels went under the knife so that a portion of dad's liver could help him live a longer, healthier life.

In the meantime, Dejon and Donovan's mother Jessica Valdepeña got a glimpse of what that life might look like, thanks to a meeting with a young woman named Lydia Hand.

Top: Lydia Hand as an infant post-transplant in 1998, with her mother, grandmother and liver transplant team. Bottom: Baby Donovan Daniels and his parents post-transplant in 2016, joined by doctors and Lydia, now 18.

Lydia, now 18, was CHLA's first living donor liver transplant patient. As an infant, she also was diagnosed with biliary atresia, a rare life-threatening disease where bile ducts cannot expel bile from the liver. In 1998, Lydia received a liver from her grandmother. Today, the Lancaster resident is a college freshman majoring in music, and says her donated liver is still going strong.

"It's pretty amazing how far she has come,” says Jessica. "I want Donovan to grow up and have a bright future just like Lydia is having."

CHLA's Liver and Intestinal Transplant Program has since grown to become one of the largest programs in the country – the hospital is now a consistent leader in the volume of living donor liver transplants performed nationwide among pediatric centers, with success rates well above national averages.

"But statistics are not the real story," says Daniel Thomas, MD, medical director of the Liver and Intestinal Transplant Program at CHLA. "It is seeing patients like Lydia Hand grow, accomplish, and live to be a happy young woman with a life full of dreams and hopes."

Coincidentally, the same team that worked on liver patient No. 1 also treated patient No. 300. Dr. Thomas, a Glendale resident, is both Lydia's and Donovan's hepatologist while Yuri Genyk, MD, of La Cañada, was their transplant surgeon.

"Donovan's success is truly the culmination of the knowledge and skills from the 299 liver transplants that preceded him, including Lydia's," says Dr. Genyk, surgical director of the Pediatric Liver Transplant Program at CHLA and associate professor of clinical surgery in the Division of Hepatobiliary Surgery and Abdominal Organ Transplantation at the Keck School of Medicine of USC. "It speaks to the expertise and dedication of the entire liver transplant team, as well as the collective support we receive from all the services CHLA provides."

Dejon Daniels sees his son Donovan for the first time since the transplant.When Donovan's parents brought him to Children's Hospital Los Angeles in October, doctors told them Donovan urgently needed a new liver. Dejon volunteered and was found to be a match. The transplant took place Nov. 18, with Dr. Genyk performing both parts – Dejon's surgery at USC in the morning and Donovan's transplant at CHLA several hours later. Dejon was released and finally was able to visit Donovan just in time for Thanksgiving.

Lydia and Donovan's family met in Donovan's hospital room on Dec. 1, the day he was discharged.

"I’ve heard all the stories about my transplant from my family, but to actually see and hear what their family is going through is a special experience," says Lydia. "Donovan is me, I was once him, and it's incredible to know that hundreds of other kids have received this life-saving procedure at CHLA in the years between us," Lydia said.

By the day Donovan left the hospital, CHLA doctors had already performed three more pediatric liver transplants.

[Higher resolution version of photos available upon request]

About Children's Hospital Los Angeles

Children’s Hospital Los Angeles is a nonprofit pediatric health care organization dedicated to creating hope and building healthier futures for children. Founded in 1901, CHLA is one of the nation’s leading children’s hospitals and is acknowledged worldwide for its leadership in pediatric and adolescent health. CHLA is one of only 11 children’s hospitals in the nation—and the top-ranked pediatric facility in California—to be named to the prestigious U.S. News & World Report Honor Roll for 2016-17.

For more information, visit CHLA.org. Follow us on Twitter, Facebook, YouTube and LinkedIn, or visit our blog: CHLA.org/BLOG


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