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Medicine

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Cancer, Metastasis, Metastasis research, LOX, cancer surgery, Israel

Discovery Could Lead to Ways for Decreasing Metastatic Disease

An international research team has discovered a central mechanism that accelerates the development of metastases after surgery for cancerous tumors in the abdominal area. This study provides a possible treatment modality for cancer patients that can decrease incidence of deadly metastatic disease.

Medicine

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Research, Calories, Circadian Rhythms, O’Donnell Brain Institute, Ut Southwestern

Study: Eating at ‘Wrong Time’ Affects Body Weight, Circadian Rhythms

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A new high-precision feeding system for lab mice reinforces the idea that the time of day food is eaten is more critical to weight loss than the amount of calories ingested.

Medicine

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Brain, Brain Activity Imaging, Depresion, Neural Activity, neuro circuits

New Study of Brain Circuits Finds Key Links to Symptoms of Depression

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Scientists have linked specific wiring in the brain to distinct behavioral symptoms of depression. In a study published in Cell, researchers at UC San Diego found brain circuits tied to feelings of despair and helplessness and were able to alleviate and even reverse such symptoms in mice studies.

Medicine

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zika, Pregnancy, Zika birth defects, Vaccine

Vaccines Protect Fetuses From Zika Infection, Mouse Study Shows

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A new study in mice shows that females vaccinated before pregnancy and infected with Zika virus while pregnant bear pups who show no trace of the virus. The findings offer the first evidence that an effective vaccine can protect vulnerable fetuses from Zika infection and resulting injury.

Medicine

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Herpes, Ophthalmology

Researchers at UIC Identify Master Molecule Behind Corneal Inflammation

Researchers at the University of Illinois at Chicago have identified an enzyme present in the cornea that becomes dramatically upregulated and triggers inflammation during and even after a herpes virus infection has cleared.

Medicine

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IBD, Inflammatory Bowel Disease, Colitis, Microbiome, Antibiotics

Antibiotics Taken Late in Pregnancy Can Increase Risk for Inflammatory Bowel Diseases in Offspring

A study by researchers at the University of Chicago Medicine shows that when mice that are genetically susceptible to developing inflammatory bowel disease (IBD) were given antibiotics during late pregnancy and the early nursing period, their offspring were more likely to develop an inflammatory condition of the colon that resembles human IBD.

Medicine

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Type 2 Diabetes, Metabolic Disease, Endocrinology and Diabetes, Hepatology, Nonalcoholic Fatty Liver Disease, Gastroenterology, drug repurposing, Inflammation

Repurposed Asthma Drug Shows Blood Sugar Improvement Among Some Diabetics

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After 12 weeks of taking an anti-asthma drug, a subset of patients with type 2 diabetes showed a clinically significant reduction in blood glucose during a randomized, double blind, placebo-controlled clinical trial, report University of California San Diego School of Medicine and University of Michigan researchers.

Medicine

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St. Jude Children's Research Hospital, T Cells, immune-checkpoint blockade , immune checkpoint blockade therapy, epigenitcs, T cell exhaustion, Chronic viral infection, HIV, epigenetic control, Immunology

Researchers Chart Pathway to ‘Rejuvenating’ Immune Cells to Fight Cancers and Infections

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St. Jude Children’s Research Hospital discovery of the mechanism of T cell exhaustion will lead to treatments to enhance immunotherapies against cancers and such viruses as HIV

Medicine

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Anti-obesity Hormone, Leptin, Hormone Leptin, Protein, Obesity, Cell Metabolism, HMS, Harvard Medical School, Jeffrey Flier, Eleftheria Maratos-Flier, Starvation, Metabolism, obesity gene, Biology, Body Weight

Does the Emperor Have Clothes?

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Decades after the discovery of anti-obesity hormone, scant evidence that leptin keeps lean people lean, scientists caution

Science

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Dna Damage, chilling stress, selective cell death, stem cell survival

NUS Study: Plants Sacrifice “Daughters” to Survive Chilly Weather

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A new study by a team of plant biologists from the National University of Singapore found that some plants may selectively kill part of their roots to survive under cold weather conditions.







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