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Medicine

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Emerging Drug Could Help Treat a Common Liver Disease

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Treating a liver disease called NASH (non-alcoholic steatohepatitis) is difficult. Now scientists believe they have found a pharmacologic approach that may inhibit NASH, and thus stop deadly conditions that result from NASH.

Medicine

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Liver Disease

New Guidelines Aim to Prevent Medics From Failing to Diagnose Patients with Liver Disease

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New recommendations, led by experts at the University of Birmingham, have been published to improve the use of liver blood tests.

Medicine

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Bioengineer, stem cell bio-manufacturing, Regenerative Medicine, Liver Transplantation, bioengineering mass production, Cell Reports, Cell Press , Science, Research, Biomedical Research

Scientists Create Successful Mass Production System for Bioengineered Livers

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Researchers report creating a biologically accurate mass-production platform that overcomes major barriers to bioengineering human liver tissues suitable for therapeutic transplant into people.

Medicine

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Missouri Litigation Clears the Way for Hepatitis C Cure for Medicaid Recipients

Lawsuit brought by three public interest law offices leads to availability of drug developed by SLU medical professors.

Medicine

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Stem Cell Based Tissues, stem cell bio-manufacturing, Gastro Intestinal, induced pluripotent stem, technology acceleration, pediatrics disorders, Organ Transplant, liver transplant, Hirschsprung disease, Intestinal Disorders, stem cell medicine, Research & Development, Cincinnati Children's Hospital Medical Center, press release, Medical Center

Cincinnati Children’s Launches Center for Stem Cell and Organoid Medicine

Seven years ago Cincinnati Children’s scientists first used pluripotent stem cells to mimic natural human development and grow working human intestine in a lab. Today medical center doctors can bioengineer the gastrointestinal tissues of sick children to find clues about a child’s disease and how to treat it. Cincinnati Children’s is building on this early research advancement in personalized medicine by launching the Center for Stem Cell and Organoid Medicine (CuSTOM).

Medicine

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Cancer, Liver, Hepatology, Liver Cancer, Cell Biology, Genetics, Vaccines, Gastroenterology, Immunology, Hepatocellular Carcinoma

A New Strategy for Prevention of Liver Cancer Development

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Primary liver cancer is now the second leading cause of cancer-related death worldwide, and its incidences and mortality are increasing rapidly in the United Stated. In late stages of the malignancy, there are no effective treatments or drugs. However, an unexpected finding made by a team of University of California San Diego School of Medicine researchers sheds light on the development of a new strategy for prevention of liver cancer.

Medicine

Science

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Computational Biology, Computational Biomedicine, Hypertension, Genomics

Using a Mathematical Lens to Look at Disease as a Whole Body Problem

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A novel computational method allows researchers to parse how multiple organs contribute to a disease over time, giving a more holistic view of disease and potentially revealing new avenues for intervention.

Science

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toxicological sciences, Toxicology, TCE, PCE, Aflatoxin, AHR, Society Of Toxicology

Research Articles on Transcriptomics to Aid Risk Assessment, Pregnancy and Carcinogen Metabolism, and More Featured in Toxicological Sciences

Editor's Highlights include papers on aryl hydrocarbon receptor activation and neutrophil function; transcriptomic analysis of TCE and PCE in the liver and kidney; functional genomics of TCE metabolites genotoxicity; and increased aflatoxin b1 damage in pregnant mice.

Medicine

Science

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Cell Biology, Molecular Biology, Cancer, Liver Cancer, Immunotherapy

How Chronic Inflammation Tips the Balance of Immune Cells to Promote Liver Cancer

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Chronic inflammation is known to drive many cancers, especially liver cancer. Researchers have long thought that’s because inflammation directly affects cancer cells, stimulating their division and protecting them from cell death. But University of California San Diego School of Medicine researchers have now found that chronic liver inflammation also promotes cancer by suppressing immunosurveillance — a natural defense mechanism in which it’s thought the immune system suppresses cancer development. The study is published November 8 in Nature.

Medicine

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Life

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Law and Public Policy

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Rural Health, Healthcare, Robert Wood Johnson Foundation, National 4-H Council, Appalachia, Health Disparities, Racial Disparities, Prevention, Health Policy

Closing the Rural Health Gap: Media Update from RWJF and Partners on Rural Health Disparities

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Rural counties continue to rank lowest among counties across the U.S., in terms of health outcomes. A group of national organizations including the Robert Wood Johnson Foundation and the National 4-H Council are leading the way to close the rural health gap.


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