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Medicine

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Stem Cell Based Tissues, stem cell bio-manufacturing, Gastro Intestinal, induced pluripotent stem, technology acceleration, pediatrics disorders, Organ Transplant, liver transplant, Hirschsprung disease, Intestinal Disorders, stem cell medicine, Research & Development, Cincinnati Children's Hospital Medical Center, press release, Medical Center

Cincinnati Children’s Launches Center for Stem Cell and Organoid Medicine

Seven years ago Cincinnati Children’s scientists first used pluripotent stem cells to mimic natural human development and grow working human intestine in a lab. Today medical center doctors can bioengineer the gastrointestinal tissues of sick children to find clues about a child’s disease and how to treat it. Cincinnati Children’s is building on this early research advancement in personalized medicine by launching the Center for Stem Cell and Organoid Medicine (CuSTOM).

Medicine

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Cancer, Liver, Hepatology, Liver Cancer, Cell Biology, Genetics, Vaccines, Gastroenterology, Immunology, Hepatocellular Carcinoma

A New Strategy for Prevention of Liver Cancer Development

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Primary liver cancer is now the second leading cause of cancer-related death worldwide, and its incidences and mortality are increasing rapidly in the United Stated. In late stages of the malignancy, there are no effective treatments or drugs. However, an unexpected finding made by a team of University of California San Diego School of Medicine researchers sheds light on the development of a new strategy for prevention of liver cancer.

Medicine

Science

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Computational Biology, Computational Biomedicine, Hypertension, Genomics

Using a Mathematical Lens to Look at Disease as a Whole Body Problem

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A novel computational method allows researchers to parse how multiple organs contribute to a disease over time, giving a more holistic view of disease and potentially revealing new avenues for intervention.

Science

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toxicological sciences, Toxicology, TCE, PCE, Aflatoxin, AHR, Society Of Toxicology

Research Articles on Transcriptomics to Aid Risk Assessment, Pregnancy and Carcinogen Metabolism, and More Featured in Toxicological Sciences

Editor's Highlights include papers on aryl hydrocarbon receptor activation and neutrophil function; transcriptomic analysis of TCE and PCE in the liver and kidney; functional genomics of TCE metabolites genotoxicity; and increased aflatoxin b1 damage in pregnant mice.

Medicine

Science

Channels:

Cell Biology, Molecular Biology, Cancer, Liver Cancer, Immunotherapy

How Chronic Inflammation Tips the Balance of Immune Cells to Promote Liver Cancer

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Chronic inflammation is known to drive many cancers, especially liver cancer. Researchers have long thought that’s because inflammation directly affects cancer cells, stimulating their division and protecting them from cell death. But University of California San Diego School of Medicine researchers have now found that chronic liver inflammation also promotes cancer by suppressing immunosurveillance — a natural defense mechanism in which it’s thought the immune system suppresses cancer development. The study is published November 8 in Nature.

Medicine

Science

Life

Business

Law and Public Policy

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Rural Health, Healthcare, Robert Wood Johnson Foundation, National 4-H Council, Appalachia, Health Disparities, Racial Disparities, Prevention, Health Policy

Closing the Rural Health Gap: Media Update from RWJF and Partners on Rural Health Disparities

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Rural counties continue to rank lowest among counties across the U.S., in terms of health outcomes. A group of national organizations including the Robert Wood Johnson Foundation and the National 4-H Council are leading the way to close the rural health gap.

Medicine

Channels:

Cancer, Liver Cancer, Liver Transplant, Bile Duct Cancer

New Multidisciplinary Liver Tumor Program Targets Liver Cancer

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Perlmutter Cancer Center introduces new liver tumor program to tackle liver and biliary cancers and tumors.

Medicine

Channels:

Medicine And Health, Metabolic Diseases, Fatty Liver Disease, Obesity, Cell Biology

Fat Hormone Linked to Progression of Fatty Liver Disease May Hold Key to New Treatments

The rising obesity epidemic has brought with it an army of maladies. One, in particular, is threatening to outpace many of the disorders that accompany obesity, in terms of occurrence and severity: nonalcoholic fatty liver disease.

Medicine

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Transplant, Liver, Liver Transplant, Tennessee Valley Healthcare System

Vanderbilt’s Liver Transplant Program Reaches New Milestone

This month, Vanderbilt University Medical Center (VUMC) performed its 2,000th liver transplant, another milestone for one of the largest liver transplant programs in the Southeast.

Medicine

Channels:

Hepatitis C, HCV, liver transplant, HCV transmission, liver donor, liver donation, Liver Disease

Use of Hepatitis C Positive Liver Organs

Use of liver organs from selected hepatitis C positive donors should be considered due to modest risk of hepatitis C transmission and the availability of safe and effective direct‐acting antiviral therapies, according to research presented this week at The Liver Meeting® — held by the American Association for the Study of Liver Diseases.


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