Learn how ancestry changes genetic risk variants’ impact on type 2 diabetes in childhood cancer survivors & alkylating agent exposure magnifies diabetes risk.
An intricate simulation performed by UT Southwestern Medical Center researchers using one of the world’s most powerful supercomputers sheds new light on how proteins called SNAREs cause biological membranes to fuse.
New research by scientists at University of California San Diego has shown that cells regulate cAMP/PKA signaling by forming liquid droplets that segregate excess PKA catalytic subunits where they can do no harm. Some cancers may block the formation of liquid droplets, leading to hyperactive signaling and tumor formation.
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Mitchell A. Lazar, M.D., Ph.D., the Rhoda and Willard Ware Professor in Diabetes and Metabolic Disease, and Director of the Institute for Diabetes, Obesity, and Metabolism in the Perelman School of Medicine at the University of Pennsylvania, is the 2025 recipient of the George M. Kober Medal from the Association of American Physicians (AAP). Lazar will receive the honor in Chicago at the AAP’s annual meeting which takes place April 25-27, 2025.
The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.
A research team from the National University of Singapore (NUS) has unearthed new findings which may help explain the connection between cancer risk and poor diet, as well as common diseases like diabetes, which arise from poor diet.
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Researchers from UC San Diego have discovered the biochemical workings of an old-fashioned diabetes drug, and it's helping them develop new, safer alternatives.
A recent study by Case Western Reserve University used national data from U.S. military veterans with diabetes to validate and modify a widely accepted model used to predict the risk of heart failure in diabetic patients.
New research published in The Journal of Clinical Endocrinology & Metabolism finds a high prevalence of type D personality among people with hypothyroidism.
Combining a low dose of blood pressure medication with a higher intake of dietary-resistant starch might help stave off diabetic kidney disease, according to results from a new animal study. Researchers will present their work this week at the American Physiology Summit.
Heavy alcohol use may increase middle-aged adults’ risk of developing Type 2 diabetes, according to research to be presented this week at the American Physiology Summit in Long Beach, California. The Summit is the flagship annual meeting of the American Physiological Society (APS).
Four UChicago Medicine faculty members were elected to the 2024 class of the Association of American Physicians (AAP), a prestigious medical society that acknowledges the nation's leading physician-scientists.
Today, L-Nutra, the premier nutri-technology company, unveiled the results of a pioneering clinical trial, published in Diabetologia, which aims to redefine the approach to managing Type 2 Diabetes.
A recent Mayo Clinic study suggests that active workstations incorporating a walking pad, bike, stepper and/or standing desk are successful strategies for reducing sedentary time and improving mental cognition at work without reducing job performance.
The Endocrine Society selected Ana Canton, M.D., Ph.D., as the recipient of its 2024 C. Wayne Bardin, MD, International Travel Award for her outstanding ENDO abstract and her research contributions to the care of patients with pediatric endocrine disorders.
While CRISPR has shown immense promise as a next-generation therapeutic tool, the gene editing technology’s edits are still imperfect. Researchers have developed a new system to test and analyze CRISPR-based DNA repair and related risks from unintended but harmful “bystander” edits.
Mesenchymal stromal cells (MSCs) hold great promise for tissue regeneration in debilitating disorders. Despite reported improvements, the short-term outcomes of MSC transplantation, which is possibly linked to poor cell survival, demand ext
High glucose (HG) culture conditions in vitro and persistent exposure to hyperglycemia in diabetes patients are detrimental to stem cells, analogous to any other cell type in our body. It interferes with diverse signaling pathways, i.e. mam
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With diabetes increasing at an alarming rate in the United States, Diabetes Alert Day® is meant to be a one-day “wake-up call” to the seriousness of diabetes and the importance of understanding your risk. The sooner you know your risk, the sooner you can take steps to prevent or even learn to manage the disease
New research conducted in mice offers insights into what’s going on at the molecular level that could cause people with diabetes to develop Alzheimer’s disease.
Surgical nerve decompression, used to treat conditions such as carpal tunnel syndrome and sciatica, could play a role in relieving the pain of diabetic neuropathy patients, researchers at UT Southwestern Medical Center found.
This paper summarizes the materials of microneedles, techniques, structure, design, release mechanism, classification of delivered substances and their effects on different stages of wound healing.
A study has unveiled that exosomes, extracted from adipose mesenchymal stem cells (ADSC-Exos), markedly speed up the healing process of skin wounds in diabetic mice. This discovery tackles the pressing global health issue of diabetic wounds, notorious for precipitating grave complications and impairments.
Omeza®, a regenerative skincare company that develops marine-based therapies for the treatment of chronic wounds, today presented positive interim data from a diabetic foot ulcer (DFU) clinical trial showing that Omeza® OCM™ plus offloading of weight on the affected foot achieved a 91 percent area reduction (PAR) rate in DFUs within twelve weeks, and a 63 percent PAR within four weeks.
New study finds that getting less than 45% of total energy from carbohydrates is not associated with elevated mortality risk compared with groups that consume more carbohydrates.
Glucagon-like peptide-1 (GLP-1) agonists such as Ozempic® or Wegovy® (semaglutide), Saxenda® (liraglutide), or Zepbound™ (tirzepatide), have become increasingly popular in promoting weight loss.
Are you one of the 530 million people who have diabetes? If so, it is also likely you have kidney disease. It's one of the most pressing global health challenges and scientists are scrambling to find new treatments and diagnostic markers for diabetic kidney disease. University of South Australia Research Fellow Dr Jantina Manning explains an exciting new discovery in her lab that could provide hope for millions of people living with diabetes and associated kidney disease. Thursday 14 March is World Diabetes Day.
It has been well established that people who live in rural areas in the U.S. are more likely to have diabetes and experience barriers to managing their condition compared to those who live in the suburbs and cities.
Loyola Medicine Nephrologist Sylvester Barnes is available to discuss a new study which showed Ozempic cut the risk of kidney disease progression and related health complications in diabetic patients.
A landmark study conducted at four sites, including Joslin Diabetes Center, reports that people with type 2 diabetes who underwent bariatric surgery achieved better long-term blood glucose control compared to people who received medical management plus lifestyle interventions. Participants who underwent bariatric surgery, also called metabolic or weight-loss surgery, were also more likely to stop needing diabetes medications and had higher rates of diabetes remission up to 12 years post-surgery. The findings, published in JAMA, suggest that weight loss surgery may carry benefits for people with diabetes, even those who are below the traditional BMI threshold of 35 for bariatric surgery.
Endocrine Society members elected Carol Lange, Ph.D., of the University of Minnesota in Minneapolis, Minn., as its 2025-2026 President. She will serve as President-Elect for a year beginning in June 2024 before becoming President in June 2025.
Semaglutide is a safe, effective therapy for a common fatty liver disease in people with HIV, according to the results of a clinical trial presented by UTHealth Houston.
After spending more than three decades managing her diabetes, Pam Mirabile was alarmed by swelling in her foot. She visited Loyola Medicine podiatric surgeon Katherine Dux, DPM, who diagnosed her with Charcot foot, a rare complication of diabetes.
Alzheimer’s disease and Type 2 diabetes are part of a family of amyloid diseases that are characterized by having proteins that cluster together. University of Washington researchers have demonstrated more similarities between the two diseases.
Better prevention of Type II diabetes could save both lives and money. The U.S. spends over $730 billion a year — nearly a third of all health care spending — on treating preventable diseases like diabetes.