Feature Channels: Stem Cells

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Released: 27-Oct-2022 12:00 PM EDT
Antimicrobial peptide-loaded decellularized placental sponge as an excellent antibacterial skin substitute against XDR clinical isolates
Preprints

Hatef Ghasemi Hamidabadi, Sanaz Alizadeh, Leila Mahboobi, Zahra Khosrowpour, Maryam Nazm Bojnordi, Zahra Aliakbar Ahovan, Majid Malekzadeh Shafaroudi, Maria Zahiri, Narendra Pal Singh Chauhan, Mazaher Gholipourmalekabadi

Released: 27-Oct-2022 12:00 PM EDT
Transcription factor HSFA7b controls ethylene signaling and meristem maintenance at the shoot apical meristem during thermomemory
Preprints

Sheeba John, Federico Apelt, Amit Kumar, Dominik Bents, Maria Grazia Annunziata, Franziska Fichtner, Bernd Mueller-Roeber, Justyna J. Olas

Released: 27-Oct-2022 12:00 PM EDT
Tumor-educated Gr1+CD11b+cells instigate breast cancer metastasis by twisting cancer cells plasticity via OSM/IL6-JAK signaling
Preprints

Sanam Peyvandi, Manon Bulliard, Annamaria Kauzlaric, Oriana Coquoz, Yu-Ting Huang, Nathalie Duffey, Laetitia Gafner, Girieca Lorusso, Nadine Fournier, Qiang Lan, Curzio Rüegg

Released: 27-Oct-2022 12:00 PM EDT
Influential factors for optimizing and strengthening mesenchymal stem cells and hematopoietic stem cells co-culture
Preprints

Mandana Shirdarreh, Fatemeh Amiri, Mohammad Pouya Samiee, Armita Safari

Released: 27-Oct-2022 12:00 PM EDT
KDM6A/UTX promotes spermatogenic gene expression across generations but is dispensable for male fertility
Preprints

Benjamin William Walters, Shannon R Rainsford, Nicolas Dias, Xiaofang Huang, Dirk G de Rooij, Bluma J Lesch

Newswise: NIH researchers home in on a new cause of Stargardt disease
Released: 27-Oct-2022 11:30 AM EDT
NIH researchers home in on a new cause of Stargardt disease
NIH, National Eye Institute (NEI)

Using a new stem-cell based model made from skin cells, scientists found the first direct evidence that Stargardt-related ABCA4 gene mutations affect a layer of cells in the eye called the retinal pigment epithelium (RPE).

Newswise: Profiling of Fatty Sweet Molecules on Cell Surfaces
Released: 27-Oct-2022 6:00 AM EDT
Profiling of Fatty Sweet Molecules on Cell Surfaces
University of Vienna

Glycolipids, basically "fatty sweet" molecules, are a relatively unknown group of lipids. A new method developed by an Austrian team led by chemist Evelyn Rampler of the University of Vienna has now provided deeper insights into the functioning of certain glycolipids located on the surfaces of stem cells.

   
Released: 26-Oct-2022 12:00 PM EDT
Exosomes from circ-Astn1-modified adipose-derived mesenchymal stem cells enhance wound healing through miR-138-5p/SIRT1/FOXO1 axis regulation
World Journal of Stem Cells

BACKGROUNDWound healing impairment is a dysfunction induced by hyperglycemia and its effect on endothelial precursor cells (EPCs) in type 2 diabetes mellitus. There is increasing evidence showing that exosomes (Exos) derived from adipose-derive

Released: 26-Oct-2022 12:00 PM EDT
Maternal inappropriate calcium intake aggravates dietary-induced obesity in male offspring by affecting the differentiation potential of mesenchymal stem cells
World Journal of Stem Cells

BACKGROUNDThe effects of inappropriate dietary calcium intake in early life on later obesity have not been fully elucidated. AIMTo raise the mechanism of maternal calcium intake on the multi-differentiation potential of mesenchymal stem cells

Newswise: Even Good Gene Edits Can Go Bad
Released: 24-Oct-2022 7:15 PM EDT
Even Good Gene Edits Can Go Bad
Rice University

A Rice University lab is leading the effort to reveal potential threats to the efficacy and safety of therapies based on CRISPR-Cas9, the Nobel Prize-winning gene editing technique, even when it appears to be working as planned.

Released: 24-Oct-2022 5:15 PM EDT
The New York Stem Cell Foundation Names Dr. Derrick Rossi as Interim CEO
New York Stem Cell Foundation (NYSCF)

The New York Stem Cell Foundation (NYSCF) announced Dr. Derrick Rossi, a member of the NYSCF Board of Directors and co-founder of Moderna, as Interim CEO of NYSCF.

Released: 24-Oct-2022 2:55 PM EDT
University Hospitals Seidman Cancer Center Researchers Slash Time Needed to Produce CAR T-Cells
University Hospitals Cleveland Medical Center

Researchers at University Hospitals (UH) Seidman Cancer Center in Cleveland, Ohio and a biotech start-up company have developed a streamlined way to manufacture CAR T-cells for immunotherapy treatment in just 24 hours – an improvement over the team’s previous benchmark of eight days and commercial suppliers that typically take three weeks. The team is one of the first in the country to test this manufacturing approach.

Released: 21-Oct-2022 12:00 PM EDT
Short-term exposure of human minor salivary gland stem cells to hypergravity enhances stemness
Preprints

Jeong-Seok Choi, Tri Ho Minh, Jeong Mi Kim, Mi Eun Choi, Eun Jeong Jeon, Jin-Mi Park, Sungryeal Kim, Young Mo Kim

Newswise: Researchers find that different stem cells are responsible for the repair of different kinds of bone injuries
19-Oct-2022 5:05 PM EDT
Researchers find that different stem cells are responsible for the repair of different kinds of bone injuries
UT Southwestern Medical Center

The discovery that different bone-forming stem cells are responsible for different aspects of bone maintenance and repair will allow us to focus future bone regeneration efforts

   
Released: 20-Oct-2022 12:00 PM EDT
Recovery of physical function, muscle mass and quality of life in patients undergoing allogeneic hematopoietic stem cell transplantation
Preprints

Takahiro Takekiyo, Atae Utsunomiya, Souichiro Nara, Nozomi Mori, Norihisa Nakashima, Toshiyuki Okamura, Masahito Tokunaga, Takayoshi Miyazono, Nobuaki Nakano, Yoshikiyo Ito, Koichiro Dozono

Released: 20-Oct-2022 12:00 PM EDT
KLF2 regulates neural differentiation of dental pulp-derived stem cells by modulating autophagy and mitophagy
Preprints

Hiranmoy Das, Prateeksha Prateeksha, Prathyusha Naidu, Manjusri Das, Derek Barthels

Released: 20-Oct-2022 12:00 PM EDT
3D genome topologies distinguish pluripotent epiblast and primitive endoderm cells in the mouse blastocyst
Preprints

Gesa Loof, Dominik Szabo, Vidur Garg, Alexander Kukalev, Luna Zea-Redondo, Rieke Kempfer, Thomas M Sparks, Yingnan Zhang, Christoph J Thieme, Silvia Carvalho, Anja Weise, Milash Balachandran, Thomas Liehr, Lonnie R Welch,

Released: 20-Oct-2022 12:00 PM EDT
Architected Hydrogels for Functional Tissue Engineering Applications
Preprints

Doris Zauchner, Monica Zippora Müller, Sophie Zengerle, Adam Aleksander Korczak, Muriel Alexandra Holzreuter, Xiao-Hua Qin

Released: 20-Oct-2022 12:00 PM EDT
Parishin A-loaded Mesoporous Silica Nanoparticles Modulate Macrophage Polarization to Attenuate Tendinopathy
Preprints

Yan Liu, Lisha Zhu, Shanshan Jin, Yu Wang, Yuting Niu, Ming Yu, Zixin Li, Liyuan Chen, Xiaolan Wu, Chengye Ding, Tianhao Wu, Xinmeng Shi, Yixin Zhang, Dan Luo

Released: 20-Oct-2022 12:00 PM EDT
Comprehensive analysis of m6A related gene mutation characteristics and prognosis in colorectal cancer
Preprints

Tao Jiang, Linshuai Xing, Lipeng Zhao, Ziqi Ye, Dong Yu, Shengtao Lin

Newswise: Stem Cell Study Reveals How Neurons From PTSD Patients React to Stress
18-Oct-2022 3:30 PM EDT
Stem Cell Study Reveals How Neurons From PTSD Patients React to Stress
Mount Sinai Health System

Stem cell-derived neurons from combat veterans with post-traumatic stress disorder (PTSD) react differently to a stress hormone than those from veterans without PTSD, a finding that could provide insights into how genetics can make someone more susceptible to developing PTSD following trauma exposure.

Released: 18-Oct-2022 12:00 PM EDT
Ostrich Eggshell – Hydroxyapatite Composite as a Safe Scaffold with Osteoinductive Properties
Preprints

Farideh Alahgahi, Esmail Fattahi, Mohsen Saeidi, Mir Mahmoud Mortazavi

Released: 17-Oct-2022 12:00 PM EDT
Mitochondrial complex I controls blood brain barrier permeability
Preprints

Gavin M Davis, Estelle Juere, Jerrard M Hayes, Gavin P Davey

Released: 17-Oct-2022 12:00 PM EDT
Development of a highly sensitive immunoassay to measure ataxin2 as a target engagement marker in Spinocerebellar Ataxia Type 2
Preprints

Jessica Bux, Nesli Ece Sen, Isa-Maria Klink, Stefan Hauser, Ludger Schöls, Georg Auburger, Olaf Horst Riess, Jeannette Hübener-Schmid

Released: 17-Oct-2022 12:00 PM EDT
Human organoid model of PCH2a recapitulates brain region-specific pathology
Preprints

Theresa Kagermeier, Stefan Hauser, Kseniia Sarieva, Lucia Laugwitz, Samuel Groeschel, Wibke Janzarik, Zeynep Yentuer, Katharina Becker, Ludger Schoels, Ingeborg Kraegeloh-Mann, Simone Mayer

Released: 17-Oct-2022 12:00 PM EDT
Leak current, even with gigaohm seals, can cause misinterpretation of stem cell-derived cardiomyocyte action potential recordings
Preprints

Alexander Phillip Clark, Michael Clerx, Siyu Wei, Chon Lok Lei, Teun de Boer, Gary R Mirams, David J Christini, Trine Krogh-Madsen

Released: 17-Oct-2022 12:00 PM EDT
Type 2 Inflammation Drives an Airway Basal Stem Cell Program Through Insulin Receptor Substrate Signaling
Preprints

Xin Wang, Nils Hallen, Minkyu Lee, Sachin Samuchiwal, Qihua Ye, Kathleen Buchheit, Alice Maxfield, Rachel Roditi, Regan Bergmark, Neil Bhattacharyya, Tessa Ryan, Deb Gakpo, Soumya Raychaudhuri, Dan Dwyer,

Released: 17-Oct-2022 12:00 PM EDT
MicroRNAs 7/17/155 As A Potential Breast Tumor Stemness miRNA Cluster: Detection of Breast Cancer Grade Specific miRNA-mRNA Interaction Network Inspiration from Mammary Gland Development
Preprints

Saeed Khodayari, Hamid Khodayari, Haniyeh Jallali, Elnaz Saeedi, Ali Faryabi, Meghdad Yeganeh, Ahad Mohammadnejad, Amirnader Emami Razavi, Mohammad Dashtkoohi, Farimah Hadjilooei, Reza Shirkoohi, Ramesh Omranipour, Karim Nayernia, Habibollah Mahmoodzadeh

Released: 17-Oct-2022 12:00 PM EDT
Single-cell Landscape Analysis of the Circulating Human B Cell Pool under Selective Pressure of Allogeneic Stem Cell Transplantation
Preprints

Jonathan C Poe, Jiyuan Fang, Dadong Zhang, Marissa R Lee, Rachel A DiCioccio, Hsuan Su, Xiaodi Qin, Jennifer Zhang, Jonathan Visentin, Sonali J Bracken, Vincent T Ho, Kathy S Wang, Jeremy J Rose, Steven Z Pavletic,

Released: 17-Oct-2022 12:00 PM EDT
Poly(ε-caprolactone)-based nanofibrous scaffold incorporated with decellularized bone extracellular matrix as a potential strategy for bone regeneration
Preprints

Ming Zhang, Quan Zhou, Qiangsheng Dong, Jue Zhang, Xin Zhou, Hao Huang, Junchen Bao, Hongjian Shan, Furong Sun, Liangliang Li



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