During stroke or heart attack, tissue damage can be limited because “collateral” vessels connect the tissue to other arteries. Collateral vessels can vary greatly in size and number from one person to the next. Scientists have now implicated the Rabep2 gene as a major contributor to variation.
Cardiovascular disease, including heart disease and stroke, kills more than 800,000 Americans each year. We know that too much salt may contribute to high blood pressure and increased cardiovascular risk. According to a new study in the Journal of the Academy of Nutrition and Dietetics, American children are consuming sodium at levels that far exceed the daily recommended limit. Taste preferences for high sodium foods, formed as children, follow individuals into adulthood and put them at increased risk for developing cardiovascular problems later in life.
The 2016 Mount Sinai ADVANCED Heart Disease Symposium is a one-day intensive state-of-the-art review of heart failure and advanced cardiac care, consisting of didactic lectures, debates and expert panel discussions of emerging or controversial topics in heart failure, mechanical circulatory support and cardiac transplantation.
Initial results from the largest, prospective evaluation of a percutaneous transcatheter left atrial appendage (LAA) closure device (Amplatzer Amulet) for stroke prevention in patients with non-valvular atrial fibrillation show that the device has a high implant success rate and low major adverse events.
Using specialized CT scans of a healthy heart and one with heart disease, a team of Johns Hopkins cardiologists and biomedical engineers say they've created computer models of the "shape" of blood flow through the heart's upper left chamber that someday may help predict stroke risk.
Inflammation is one of the main reasons why people with diabetes experience heart attacks, strokes, kidney problems and other, related complications. Now, in a surprise finding, researchers at Washington University School of Medicine in St. Louis have discovered, in mice, that when certain immune cells can’t manufacture fat, the mice don’t develop diabetes and inflammation, even when consuming a high-fat diet.
A randomized evaluation of routine follow-up coronary angiography after percutaneous coronary intervention (PCI) found that there was no long-term clinical benefit compared to clinical follow-up alone among unselected patients following PCI.
A dedicated stent study conducted exclusively in women and minority patients evaluated clinical outcomes within the era of contemporary PCI, comparing these results to a parallel cohort of white male patients. Although there were no significant differences in stent-related outcomes, both groups had higher rates of death and myocardial infarction (MI) in the first year following the procedure.
Final results from the RESPECT trial found that percutaneously closing a patent foramen ovale (PFO) using the Amplatzer PFO Occluder was superior to medical management in the prevention of recurrent ischemic stroke in patients who previously had a cryptogenic stroke.
Two-year results from COLOR, the first large-scale multicenter prospective study of its kind, found that PCI on coronary artery lipid-rich plaque (LRP) detected by near infrared spectroscopy (NIRS) was not associated with subsequent major adverse cardiac events (MACE) compared to PCI of non-LRPs.
A substudy of the PARTNER I Trial and Continued Access Registry found that hemodynamic trends in patients who received transcatheter aortic valve replacement (TAVR) showed excellent durability without significant structural valve deterioration at five years. The trial represents the largest to-date longitudinal analysis of echocardiographic hemodynamic parameters systematically assessed by a core laboratory.
Patients with severe aortic stenosis (AS) at intermediate surgical risk, and who are treated with transcatheter aortic valve replacement (TAVR) had improved health status at one month compared with surgical aortic valve replacement (SAVR) but two-year quality of life outcomes were similar. Prior studies have shown that TAVR results in an early quality of life (QoL) benefit in patients at high surgical risk; however, the effect of TAVR versus. SAVR on QoL in intermediate risk patients was unknown prior to this study.
A multicenter randomized trial evaluating the role of embolic protection using the Sentinel device during transcatheter aortic valve replacement (TAVR) found that the device was safe but did not meet the primary efficacy endpoint of reduction in median new lesion volume in protected territories assessed by MRI at 2-7 days. In addition, neurocognitive function was not significantly improved.
An international study has found that transcatheter cerebral embolic protection (TCEP) is safe, provides effective capture of embolic debris and does not change neurocognitive function for transcatheter aortic valve replacement (TAVR) patients.
A study in the American Journal of Critical Care found that patients with both fatigue and depression were hospitalized more than those without either condition. They also had more visits to the emergency department and longer lengths of stay.
Normal, healthy heart muscle is well-supplied with oxygen-rich blood. But UT Southwestern Medical Center cardiologists have been able to regenerate heart muscle by placing mice in an extremely low-oxygen environment.
Researchers with the UCI Susan Samueli Center for Integrative Medicine have found that regular electroacupunture treatment can lower hypertension by increasing the release of a kind of opioid in the brainstem region that controls blood pressure.
The 28th annual Transcatheter Cardiovascular Therapeutics (TCT), the annual scientific symposium of the Cardiovascular Research Foundation (CRF) featured a number of first report investigations on novel stents that could become the next generation of bioresorbable stents in patients.
A first-in-human study of a new polymer-free drug-filled stent, which provides controlled drug elution from an internal lumen, indicated non-inferior in-stent late lumen loss at nine-months compared with historical zotarolimus-eluting stent (Resolute) data. In addition, there was no binary restenosis, and a high degree of early stent strut coverage with minimal malapposition.
A large-scale randomized trial examining percutaneous coronary intervention (PCI) versus coronary artery bypass graft surgery (CABG) in patients with left main coronary artery disease (LMCAD) and low-intermediate SYNTAX scores found that there was no significant difference in three-year outcomes between the two treatments, with a reduction in 30-day major adverse events with PCI.
Coronary artery bypass (CABG) surgery is the standard treatment for revascularization in patients with left main coronary artery (LMCA) disease, but use of percutaneous coronary intervention (PCI) for this indication is increasing. Findings from the Nordic–Baltic–British Left Main Revascularization Study (NOBLE) trial found that despite similar mortality, the five-year risk of major adverse events was higher after PCI compared to CABG for the treatment of unprotected LMCA disease.
The sudden death of a 13-year-old boy resulted in more than 20 relatives to be incorrectly diagnosed as having a potentially lethal heart rhythm condition. This erroneous diagnosis occurred as a result of inappropriate use of genetic testing and incorrect interpretation of genetic test results, according to Mayo Clinic research published in Mayo Clinic Proceedings.
The two-year results from LEADERS FREE, the first randomized clinical trial dedicated to high bleeding risk patients treated with one month of dual antiplatelet therapy (DAPT), found that a polymer-free drug-coated stent (DCS) remained both significantly safer and more effective than the comparator bare-metal stent (BMS) used in the trial.
Results of a large-scale, multicenter study found that treatment with two thin-strut drug-eluting stents were both non-inferior to a durable polymer drug-eluting stent and showed favorable clinical outcomes at one year in treating an all-comers population with a high proportion of patients with acute coronary syndromes.
Although percutaneous coronary intervention (PCI) is most commonly guided by angiography alone, results from a new study investigating adjunctive imaging modalities showed that the use of a novel optical coherence tomography (OCT)-based stent sizing strategy results in similar minimal stent area (MSA) compared to intravascular ultrasound (IVUS)-guided PCI. Imaging-guided PCI (with both OCT and IVUS) also resulted in improved stent expansion and acute stent-based procedural success compared to angiography-guided PCI.
The large multinational randomized BIONICS study found that a novel ridaforolimus-eluting stent (BioNIR) was non-inferior to a zotarolimus-eluting stent (Resolute) for one-year clinical outcomes in a broad, less selected ‘more comers’ population. Results of this trial will be submitted to the FDA for U.S. approval of this novel drug-eluting stent.
Optical coherence tomography (OCT) provides safe and improved guidance for patients undergoing percutaneous coronary intervention to treat coronary artery disease, according to results from the ILLUMIEN III: OPTIMIZE PCI trial.
The Cardiovascular Research Foundation (CRF) is pleased to announce the launch of a new international journal focusing on the diagnosis and treatment of structural heart disease and the importance of the heart team in managing these disorders.
Halloween is here, and with it come haunted houses and corn mazes, mummies, ghosts and creatures of the night jumping out at you—all sure to give a harmless fright, or so we thought. Can that scary monster sneaking up behind you actually scare you to death? The answer may be as spooky as it gets.
NCDR ACTION Registry–GWTG Platinum award recognizes high standards of care
Four innovative studies exploring ways to reduce complications related to heart surgery or minimize patient mortality due to risks associated with low blood pressure and surgery were highlighted during the Anesthesiology Major Trials Session held at the ANESTHESIOLOGY® 2016 annual meeting.
Researchers at UT Southwestern Medical Center’s Hamon Center for Regenerative Science and Medicine have identified a pathway essential to heart formation and, in the process, unveiled a mechanism that may explain how some previously puzzling segments of the genome work.
The Cardiovascular Research Foundation (CRF) is pleased to announce the launch of the new TCTMD (www.tctmd.com), the leading online resource for cutting-edge news and information in interventional cardiology and beyond.
Fine particulate matter air pollution may be associated with blood vessel damage and inflammation among young, healthy adults, according to new research in Circulation Research, an American Heart Association journal.
Queen Latifah and UCLA cardiologist Dr. Karol Watson discuss what patients and their caregivers need to know about living with heart failure.
UAB doctors say stroke prevention treatments are not one-size-fits-all, and treatment options can be individualized using this hierarchical ranking.
Patients who had a stent procedure or heart bypass surgery and continued with their prescribed medical therapy had significantly better outcomes than non-adherent patients, according to a new study.
For the first time, fetal medicine experts have performed prenatal heart surgery to remove a life-threatening tumor, called intrapericardial teratoma. The patient, who underwent the operation at 24 weeks of gestation while in his mother’s womb, is now a healthy three-year-old preschooler.
The 28th annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium sponsored by the Cardiovascular Research Foundation (CRF) will feature a number of first-in-human and early feasibility trials that could impact future clinical practice. TCT, the world’s premier educational meeting specializing in interventional cardiovascular medicine, will take place October 29 – November 2, 2016 at the Walter E. Washington Convention Center in Washington, DC.
New Mom's prognosis following rare heart surgery during pregnancy is excellent with daily dilligence
A new study, whose preliminary results will be presented today at the Canadian Cardiovascular Congress and soon be published in the Journal of Cardiopulmonary Rehabilitation and Prevention, shows that even low physical fitness, up to 20% below the average for healthy people, is sufficient to produce a preventive effect on most of the risk factors that affect people with cardiovascular disease.
• Women are more likely than men to develop kidney damage following cardiovascular surgery, but researchers found no association between sex and risk of kidney damage when they analyzed studies that took patient characteristics and other factors into account.
For decades, research has suggested a link between oral health and inflammatory diseases affecting the entire body — in particular, heart attacks and strokes. Results from a randomized trial of a novel plaque identifying toothpaste, Plaque HD®, produced statistically significant reductions in dental plaque and inflammation throughout the body as measured by high sensitivity C-reactive protein (hs-CRP), a sensitive marker for future heart attacks and strokes.
– Recognizing heart failure as one of the most widespread and pernicious public health issues in the United States, Northwestern Memorial Hospital physicians and staff focused significant attention and resources on treating people in all stages of the disease, an effort that has the hospital ranked first in the United States for heart failure survival.
Thousands of people die every year because people are not carrying out life saving CPR on cardiac arrest victims before emergency services arrive, according to new research from the British Heart Foundation (BHF).
According to new research from the University of Missouri, minimal exercise may be all it takes for postmenopausal women to better regulate insulin, maintain metabolic function and help prevent significant weight gain. These findings suggest that women can take a proactive approach and may not need to increase their physical activity dramatically to see significant benefits from exercise.
New research says calcium supplements may not be heart-healthy, but UAB cardiologists are saying there is no reason to panic.
Undergoing a computer tomographic angiography was a better motivator to get people with suspected coronary artery disease to adopt healthier lifestyle practices than an exercise electrocardiography and stress test.
Mount Sinai Health System urges the general public, especially students, to learn lifesaving CPR and how to use an automated external defibrillator to reduce sudden cardiac death rates.
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