Young children who grow up with a dog or in a large family may have some protection later in life from a common inflammatory bowel disease known as Crohn’s disease, according to a study to be presented at Digestive Disease Week® (DDW) 2022.
Getting the COVID-19 vaccination strengthened one type of immune response to the SARS-CoV-2 virus in inflammatory bowel disease (IBD) patients even though they were taking immunosuppressant medication, according to investigators at Cedars-Sinai.
An innovative mobile phone application was found to be as good as expert gastroenterologists at characterizing stool specimens, according to a study by Cedars-Sinai. The artificial intelligence (AI) used in the smartphone app also outperformed reports by patients describing their stool specimens.
Cedars-Sinai physicians and scientists will share their latest advancements and research at Digestive Disease Week, known as DDW, an international scientific and clinical meeting featuring the work of physicians and researchers in gastroenterology, hepatology, endoscopy, and gastrointestinal surgery. DDW will take place May 21-24 in San Diego, California, and is available for virtual attendance.
The more antibiotics prescribed to patients 60 and older, the more likely they were to develop inflammatory bowel disease, suggesting antibiotic use could explain some of the growth in Crohn’s disease and ulcerative colitis in older people, according to a review of 2.3 million patient records in a study selected for presentation at Digestive Disease Week® (DDW) 2022.
The May issue of The American Journal of Gastroenterology features articles on abdominal bloating treatment, endoscopic brushing frequency to improve malignant biliary structure detection, and eosinophilic conditions not including eosinophilic esophagitis.
Published in Clinical Nutrition, researchers from the University of Minnesota Medical School looked at colonic hydrogen sulfide — a toxic gas in the body that smells like rotten eggs — production in people in response to animal- and plant-based diet interventions.
A multi-year study of the role of E. coli gut bacteria in Crohn’s disease finds that intestinal inflammation liberates chemicals that nourish the bacteria’s growth and promotes their ability to cause inflammation.
UC San Diego Health announces the opening of a new, multi-disciplinary clinic for patients with gastrointestinal and digestive diseases. The state-of-the-art clinic is the first of its kind in San Diego County to offer the most advanced care by a wide range of specialists under one roof.
UC San Diego study shows chronic JUUL use leads to inflammatory changes across the body, and may affect organs’ response to infection; results depend on e-cigarette flavor.
Early treatment can help overcome this life-threatening condition in premature infants. For the parents of premature babies, the condition known as necrotizing enterocolitis (NEC) is as frightening as it sounds. NEC is the most common and serious intestinal disease among premature babies. The problem inflames intestinal tissue but babies can recover and researchers are investigating new treatments.
A recent study from the Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago sheds light on what predisposes premature infants to necrotizing enterocolitis (NEC), a deadly intestinal disease. Currently, there are no targeted treatments for NEC because the causes are not well understood. The study identifies key players in the disease development, which offers promise for novel treatments.
African-American adult patients are more likely than white patients to receive substandard gastrointestinal cancer surgery, according a large study led by researchers at Yale Cancer Center. The findings are reported today in the journal JAMA Network Open.
The April issue of The American Journal of Gastroenterology includes two new guidelines—an update to the 2016 guidelines on Barrett’s Esophagus and a joint society guideline on the management of antithrombotics during GI bleeding and the periendoscopic period.
Northshore Magazine has named 125 physicians and surgeons from 32 medical specialties affiliated with Lahey Hospital & Medical Center to its annual ‘Top Doctors’ guide. Drawing from a Castle Connolly Medical Ltd. Physician database, the list consists of Northshore-area physicians and is available in the printed version or online subscription of Northshore Magazine.
Chimeric antigen receptor (CAR) T cells can be remarkably effective in treating leukemias and lymphomas, but there are no successful immunotherapies for neuroendocrine tumors (NETs) and gastrointestinal cancers (GICs) yet. Researchers at Penn Medicine have discovered that CAR-T cells directed to a tumor antigen, CDH17, a cell surface marker expressed on both NETs and GICs but also found on healthy tissues, eliminated GICs in several preclinical models without toxicity to normal tissues in multiple mouse organs, including the small intestine and colon. The results from this study, the first to target CDH17 in neuroendocrine tumors, suggest a new class of tumor associated antigens accessible to CAR-T cells in tumors but sequestered from CAR-T cells in healthy tissues.
The American College of Gastroenterology offers an open invitation to all to enjoy a free virtual event, “Tune It Up: A Concert To Raise Colorectal Cancer Awareness,” on Thursday, March 31, 2022 at 8 pm EDT featuring dynamic performances by a talented collective of musicians.
Unbound Medicine and the American Society of Colon and Rectal Surgeons (ASCRS) announce the launch of ASCRS U – a premier educational resource available for colorectal surgeons and trainees.
Evidence-based clinical guidelines on the management of patients on common anticoagulant and antiplatelet therapies during gastrointestinal (GI) bleeding or undergoing elective endoscopy have been published jointly by the American College of Gastroenterology (ACG) and the Canadian Association of Gastroenterology (CAG).
Researchers at the University of Illinois Chicago are looking at the possibility that gastroenterological changes could be an early warning sign for Lou Gehrig's disease. Their research in animal models also shows a promising treatment to slow the disease’s progression.
Ajay Jain, M.D., professor of pediatrics, pharmacology, and physiology at Saint Louis University School of Medicine, has received funding from the National Institutes of Allergy and Infectious Diseases of the National Institutes of Health (NIH) to study Short Bowel syndrome (SBS).
Mayo Clinic experts will discuss recent advances in gastroenterology and hepatology at the first Mayo Clinic International-Sheikh Shakhbout Medical City Congress in Gastroenterology and Hepatology in Abu Dhabi, United Arab Emirates.
سيناقش خبراء مايو كلينك التطورات الحديثة في طب الجهاز الهضمي والكبد في مؤتمر مايو كلينك الدولي الأول في مدينة الشيخ شخبوط الطبية لطب الجهاز الهضمي والكبد في أبوظبي، الإمارات العربية المتحدة.
وقد دخلت مايو كلينك وشركة أبوظبي للخدمات الصحية "صحة" في مشروع مشترك عام 2019 لتشغيل مدينة الشيخ شخبوط الطبية.
A Rutgers researcher’s new formula with Investigational New Drug (IND) status has successfully alleviated a patient’s long-term severe gastrointestinal (GI) illness associated with post-acute COVID-19 syndrome, or long-haul COVID, in a recent study. The study’s results on the formula developed by Liping Zhao, Ph.D., are now published in an article titled “Nutritional Modulation of Gut Microbiota Alleviates Severe Gastrointestinal Symptoms in a Patient with Post-Acute COVID-19 Syndrome” in mBio, a peer-reviewed journal of the American Society for Microbiology.
The March issue of AJG includes several articles on new technologies and AI assists to address cirrhosis and IBS. This issue also includes articles on the role of the hospitalist, gastric cancer, colonoscopy, gastroesophageal reflux, liver transplantation, esophageal cancer, climate change considerations in GI, and more.
There are no ifs, ands or “butts” about it: March is Colorectal Cancer Awareness Month and a timely reminder to get screened for one of the deadliest—and most preventable—cancers.
Rush University System for Health is the first U.S. hospital system to offer the AI-assisted colonoscopy device in every screening procedure room. The Medtronic GI Genius™ intelligent endoscopy system helps detect colorectal polyps of varying shapes and sizes and alerts the physician in real time.
Insurance companies are telling inflammatory bowel disease patients that they must switch to biosimilars for coverage to continue. A nurse practitioner from the Carlino Family IBD Center at Penn State Health says there’s no need to stress about it.
Maria T. Abreu, M.D., a renowned gastroenterologist at the University of Miami Miller School of Medicine, has been selected as vice president of the American Gastroenterological Association (AGA).
Sildenafil, the generic version of the drug known as Viagra, could be the long-waited remedy for a group of dogs with a rare disorder called megaesophagus.
For the first time, scientists used entire human GI tracts from three organ donors to show how cell types differ across all regions of the intestines, to shed light on cellular functions, and to show gene expression differences between these cells and between individuals.
New research by University of Oregon biologists has found that the intestines help regulate the gut’s acidity, which helps keep their bacterial communities in balance. Microbiologist Karen Guillemin and neuroscientist Judith Eisen will publish their findings February 1 in the journal PLOS Pathogens.
In the study, they used a common heartburn medication in zebrafish to alter gut acidity and change microbial communities. Scientists have known for years that gut bacteria are important for digestive health. And other studies have demonstrated a strong connection between the gut and the brain. The new work links those two mostly distinct areas of research together.
A paper published this week in the journal Immunity lays the groundwork to better understand and treat Crohn’s disease. The research identified a new role for Interleukin-17A (IL-17A), an immune cell-derived cytokine, in promoting selective epithelial cell development and limiting inflammation during colitis.
An international team led by the Case Western Reserve University School of Medicine has discovered novel properties of the protein Gasdermin B that promotes repair of cells lining the gastrointestinal tract in people with chronic inflammatory disorders like Crohn’s disease and ulcerative colitis.
Gastrointestinal cancers are some of the most commonly diagnosed cancers, and they continue to be associated with poor survival outcomes. The drug adagrasib specifically targets the KRASG12C gene mutation that is common in gastrointestinal cancers and inhibits gastrointestinal function.
Diagnosed with acute liver failure and her health rapidly deteriorating, it seemed like 11-month-old Lennon would need a miracle to survive. Thanks to a team of specialists at Children’s Hospital Los Angeles, she just celebrated her third birthday.
Chronic inflammatory bowel disease (IBD) is becoming increasingly widespread. Until now, however, the underlying causes of the inflammation responses were unclear.
Using a physician anesthesiologist-led Anesthesia Care Team model increases patient access to care, compared to nurse-administered sedation for gastrointestinal (GI) endoscopy procedures, according to research being presented at the American Society of Anesthesiologists’ ADVANCE 2022, the Anesthesiology Business Event.
Researchers at UC San Diego used a multi-omics approach to investigate stool samples from patients with ulcerative colitis, a chronic inflammatory bowel disease. The team has identified the family of microbiome-derived enzymes driving the disease, and demonstrated a potential therapeutic solution.