Despite intensive research since the beginning of the pandemic, it is still unclear which components of the immune system are involved in the early control of virus replication in the respiratory tract and which therefore could help prevent COVID-19 taking a severe course.
A new study published in JCI Insight, led by Angela Wahl, PhD, Raymond Pickles, PhD, and J. Victor Garcia, PhD, with the International Center for the Advancement of Translational Science (ICATS), the Department of Microbiology and Immunology, and the Institute for Global Health and Infectious Diseases (IGHID) at the UNC School of Medicine has shown that human T cells have an important role to play in controlling infection.
University of Delaware researchers in the lab of Aditya Kunjapur, assistant professor in the College of Engineering’s Department of Chemical and Biomolecular Engineering, have engineered bacteria to synthesize an amino acid that contains a rare functional group that others have shown to have implications in the regulation of our immune system. The researchers also taught a single bacterial strain to create the amino acid and place it at specific sites within target proteins.
During last year’s mpox outbreak, the virus spread for the first time outside Africa, causing over 85,000 cases of the disease to date. Men who have sex with men account for the most infections, with a marked skew towards the young.
Paul B. Rothman, MD, has been appointed as a member of the USC Health System Board, which provides strategic oversight and governance over Keck Medicine of USC and university clinical services.
A global phase 3 clinical trial that included Ann & Robert H. Lurie Children’s Hospital of Chicago found that a year-long immunotherapy through a skin patch safely desensitized toddlers with peanut allergy, lowering the risk of a severe allergic reaction from accidental exposure. Results of this randomized, double-blind, placebo-controlled trial for children 1-3 years of age, funded by DBV Technologies, were published in the New England Journal of Medicine.
The latest space experiments from UC San Diego and Axiom Space will explore therapies for breast and colorectal cancer aboard the ISS, and monitor astronauts’ stem cell health over time.
20240208171546.png&width=400&height=400)
Memorial Sloan Kettering Cancer Center (MSK) today announced the creation of The Marie-Josée Kravis Center for Cancer Immunobiology (CCI), a hub for immunotherapy research that will elevate, centralize, and prioritize the full spectrum of immuno-oncology research across the institution. The CCI, made possible by a generous $40 million gift from Henry R. Kravis to honor the visionary leadership of his wife, Marie-Josée Kravis, Vice Chair of the MSK Board of Trustees and a renowned champion of science, will establish a strategic research infrastructure that will seamlessly unite MSK scientists and physicians to further accelerate immunotherapy treatments for people with cancer.
Researchers in UNC’s School of Medicine’s department of Microbiology and Immunology and the UNC-NC State Joint Department of Biomedical Engineering have developed a new strategy to improve drug-delivery into chronic wounds infections.
HealthPartners Institute researchers have published new data in JAMA Network Open that shows monovalent COVID-19 booster vaccinations administered in early pregnancy (before 20 weeks’ gestation) were not associated with miscarriage. The research adds to the growing understanding about the safety of COVID-19 booster vaccinations among people who are pregnant.
Since the start of the COVID-19 pandemic, a class of corticosteroids called glucocorticoids (GCs) have become established as one of the main treatment options, especially for severe cases, thanks to their anti-inflammatory and immunosuppressant action. Brazilian researchers recently discovered new ways in which these drugs influence the organism’s inflammatory response during an infection.
Tissue engineering research has shown that a skin cell type could be a new therapeutic target to accelerate the healing of burns and possibly other wounds.
Researchers from Rice University have created drug-filled microparticles that can be engineered to degrade and release their therapeutic cargo days or weeks after administration. By combining multiple microparticles with different degradation times into a single injection, the researchers could develop a drug formulation that delivers many doses over time.
This month, the World Health Organization declared an end to the Mpox emergency and urged a transition to a “robust, proactive and sustainable” response to Mpox.
ربما تكون قد سمعت عن ارتباط عَدوى فيروس الورم الحليمي البشري بالإصابة بأنواع معينة منسرطان عنق الرحم، ولكن هل كنت تعلم أن عَدوى فيروس الورم الحليمي البشري مرتبطة أيضًا بارتفاع خطر الإصابة بسرطان الفم والحلق؟
Talvez você já tenha ouvido falar sobre a relação entre a infecção por papilomavírus humano (HPV) e certos tipos de cânceres cervicais, mas você sabia que a infecção por HPV também está relacionada a um maior risco de câncer bucal e de garganta?
Es posible que haya escuchado acerca de la conexión entre la infección por el virus del papiloma humano (VPH) y ciertos tipos de cáncer del cuello del útero, pero ¿sabía que la infección por el VPH también está relacionada con un mayor riesgo de presentar cáncer de boca y de garganta?
A study led by researchers at the UCLA Jonsson Comprehensive Cancer Center suggests that IL-21, a soluble molecule involved in activating the immune system, can be a potential therapeutic target to help reduce endocrine autoimmune side effects caused by checkpoint inhibitor cancer therapy.
Researchers at Children’s Hospital of Philadelphia (CHOP) and the University of California, Los Angeles (UCLA) have developed a computational platform capable of discovering tumor antigens derived from alternative RNA splicing, expanding the pool of cancer immunotherapy targets. The tool, called “Isoform peptides from RNA splicing for Immunotherapy target Screening” (IRIS), was described in a paper published today in the Proceedings of the National Academy of Sciences.
Skin cancer is the most prevalent form of cancer in the United States, with over 5 million cases diagnosed annually. The Centers for Disease Control and Prevention reports that melanoma alone accounts for more than 8,000 deaths each year. Thankfully, skin cancer is highly preventable, making it crucial to prioritize protection. Below are some of the latest headlines in the Dermatology channel.
Giving people at high risk of PFAS exposure the opportunity to easily self-test could improve access to testing for these “forever chemicals” and lead to the early detection of detrimental health conditions, according to a new Michigan State University study. The study tested an improved approach for people to collect their own blood samples to test for PFAS without being part of an academic research study.
A team from the University of Michigan Rogel Cancer Center and School of Dentistry, led by Yu Leo Lei, D.D.S., Ph.D., have identified a mechanism in mice for how obesity affects some oral cancers’ ability to escape from the immune system.
Seemingly healthy people whose blood contained antibodies associated with a condition called antiphospholipid syndrome (APS) were significantly more likely to experience a cardiovascular event such as a heart attack or stroke than those without, a study led by UT Southwestern Medical Center scientists shows
Investigators at Cedars-Sinai Cancer found that fatty liver, a condition closely associated with obesity, promotes the spread of colorectal cancer to the liver. Their study, published today in the peer-reviewed journal Cell Metabolism, details the process at the cellular level and could change the way doctors manage the disease in some patients.
A study publishing May 11th in PLOS Biology by Ophelia Venturelli at University of Wisconsin-Madison, USA, and colleagues suggests that between-species interactions within the gut microbiome may impact the efficacy of antibiotics aimed at treating C. difficile infections.
Van Andel Institute scientists have pinpointed how a specific gene mutation triggers an inflammatory cascade that may drive development of treatment-resistant cancers.
The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.
Ludwig Cancer Research congratulates Douglas Hanahan, Ludwig Distinguished Scholar at the Lausanne Branch of the Ludwig Institute for Cancer Research, on his election as Foreign Member of the Royal Society.
An international study led by MELIS-UPF researchers from the Infection Biology and Molecular Virology laboratories has identified and characterized Schlafen 12 (SLFN 12) as a novel HIV restriction factor.
Experts from Indiana University are available to comment on trending topics for the week of May 8, including the Writer's Guild of America strike, the ongoing investigation into the leak of classified military documents on Discord, and the role of climate change in an early allergy season.
Rutgers team that created the new COVID vaccine aims to partner with a pharmaceutical company to launch human trials.
The immune system has a biological telecommunications system — small proteins known as interleukins that send signals among the leukocyte white blood cells to control their defense against infections or nascent cancer.
At the 184th ASA Meeting, Ashley Alva of the Georgia Institute of Technology will describe how attaching microbubbles to macrophages, a type of white blood cell, can create high-resolution and sensitive tracking images useful for disease diagnosis. Because of the attached microbubbles, the cells sent back an echo when hit with ultrasound, which is nonionizing and noninvasive and has great depth of penetration. This allowed the team to visualize the macrophages in vivo with high resolution and sensitivity. Visualizing macrophages in vivo could also provide a powerful tool for understanding immune responses and monitoring therapeutic efficacy.
A recent clinical trial showed that the drug combination of cemiplimab plus platinum chemotherapy can prolong survival in patients with advanced lung cancer when compared with placebo plus platinum chemotherapy. Now an analysis published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society, indicates that cemiplimab plus platinum chemotherapy also affects quality of life compared to chemotherapy alone.
UC San Diego scientists find an auto-signaling mechanism driving the T cell anti-tumor response; findings may inspire new cancer therapeutics and biomarkers.
Findings reveal a previously unknown way in which the brain and immune system talk to each other and may identify a new therapeutic target for MS and other brain disorders.
RSS
Medicine keyboard_arrow_right
Sciencekeyboard_arrow_right
Life keyboard_arrow_right
Business keyboard_arrow_right
Journal News keyboard_arrow_right
By Location keyboard_arrow_right
Meetings, Grants, and Events keyboard_arrow_right