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Have Changes in the Use of Anemia Drugs Affected Dialysis Patients’ Risk of Death and Cardiovascular Events?

A new study examines whether recent changes in the use of anemia drugs for patients on dialysis have contributed to changes in rates of death or cardiovascular events. The findings indicate that these risks appear to be decreasing for patients on dialysis as well as for older adults not on dialysis. These results suggest that recent trends in the use of anemia drugs in response to US Food and Drug Administration labeling changes and prospective payment for dialysis services have been either neutral or possibly beneficial for patients on dialysis.

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Pcsk9, Ut Southwestern, LDL cholesterol, Heart Disease, Cholesteral, PCSK9-inhibitor drug

PCSK9-Inhibitor Drug Class That Grew Out of UT Southwestern Research Becomes a Game-Changer for Patient with Extremely High Cholesterol

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A 59-year-old heart patient with dangerously high levels of cholesterol that could not be adequately reduced by statin drugs now has near-normal cholesterol levels, thanks to a new class of drugs that grew out of work done by UT Southwestern Medical Center researchers.

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Exercise

High Levels of Intense Exercise May Be Unhealthy for the Heart

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More research needed into the effect of intense exercise on heart structure and function, according to sports cardiologist writing in the Canadian Journal of Cardiology.

Medicine

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Cardiotoxicity, Mitophagy, Mitochondria, Cancer Chemotherapy, Heart Failure, heme oxygenase-1 , reactive oxygen species

Heart Damage Can Be Prevented by Overexpression of Heme Oxygenase-1

The protective effect of heme oxygenase-1 and its mechanism are described. Overexpression of this enzyme could protect the heart from life-threatening damage after cancer chemotherapy, and it also may be a way to increase the therapeutic window of such drugs.

Medicine

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Diastolic Heart Failure, Heart Failure, Heart Research, Cardiovascular Research, Clinical Trial, Diastolic, Atrial, cardiovascular devices, Research, Clinical Research, Ohio State, Heart, Heart Disease, Blood Flow

Ohio State Evaluates First Transcatheter Implant for Diastolic Heart Failure

For the first time in the U.S., a clinical trial is underway that’s evaluating a device designed to treat diastolic heart failure. The first patient enrolled in the randomized, blinded study is being treated at The Ohio State University Wexner Medical Center.

Medicine

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Physical Activity, Exercise, Running, Heart Health, Mitral Valve Repair

Heart Surgeon Runs His Daily Commute

Dr. Steven Bolling, a heart surgeon at the University of Michigan Frankel Cardiovascular Center, has run to work daily for 30 years.

Medicine

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Heart, Heartbeat, Protein Engineering, Cardiovascular, Cardiovascular Research, Biophysics, heart muscle, Heart Attack, Myocardial Infarction, calcium sensor, Calcium Signaling, Troponin, Calmodulin, Receptors, receptor modeling, Research, Ohio State

Ohio State Scientists Tune Switch for Contraction to Fix Heart Disease

For the first time, scientists at The Ohio State University have engineered new calcium receptors for the heart to tune the strength of the heartbeat in an animal model.

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Little Diet Pain, Big Health Gain

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Those who struggle with obesity, take heart. Losing as little as 5% of your body weight is enough to reap significant health benefits, according to a study published February 22 in Cell Metabolism. The randomized controlled trial of 40 obese men and women compared, for the first time, the health outcomes of 5%, 10%, and 15% weight loss. While additional weight loss further improved metabolic health, 5% weight loss was sufficient to reduce multiple risk factors for type 2 diabetes and coronary heart disease.

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Genetic Footprints of Heart Disease, Steps to Better Heart Health, Transforming Common Cell to Master Heart Cell, and more in Newswise's Heart Disease News Source

Get the latest news on heart disease, the leading cause of death for people of most ethnicities in the U.S., in the Newswise Heart Disease news source.

Medicine

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Obesity, Weight Loss, Metabolism, Diabetes, Cardiovacular Disease

In Obese Patients, 5 Percent Weight Loss Has Significant Health Benefits

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Researchers at Washington University School of Medicine in St. Louis have found that in patients with obesity, the greatest improvements to health come from losing just 5 percent of their body weight. That relatively small weight loss lowered patients’ risk for diabetes and cardiovascular disease and improved metabolic function in liver, fat and muscle tissue.







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