Political equality and democracy matter, but to improve the global distribution of wealth we must reduce global poverty, according to a new paper from faculty at Binghamton University, State University of New York.
SBP researchers have revealed how TREM2, a receptor found on immune cells in the brain, interacts with toxic amyloid beta proteins to restore neurological function. The research suggests boosting TREM2 levels in the brain may prevent or reduce the severity of neurodegenerative disorders including Alzheimer’s disease.
The implementation of Proposition 47 – which reduced the prison population by charging certain drug and property offenses as misdemeanors rather than felonies – is not responsible for the recent upticks in crime throughout California, according to a new study from researchers at the University of California, Irvine. This is the first systematic analysis to be conducted of the measure’s statewide impact since its 2014 implementation.
"Growth mindset interventions," do not work for most students in most circumstances, according to a new study co-authored by Case Western Reserve University researchers.
The present study addresses the feasibility of reinforced concrete
columns totally reinforced with glass fiber-reinforced polymer
(GFRP) bars achieving the drift requirements specified in various
codes.
Two-thirds of theater technicians and actors have experienced head impacts related to working in theater environments, according to a survey study in the March Journal of Occupational and Environmental Medicine.
A major advancement has been made on how epigenomics are studied that permits mapping a genome-scale profile of epigenetic changes using less than a couple hundred of cells, a factor of 100-300 reduction in the sample amount compared to existing alternatives. Led by Virginia Tech's Chang Lu, the innovative method has implications for deciphering disease processes such as schizophrenia, cancer and inflammation that involve epigenetic mechanisms.
Mount Sinai researchers have shown, for the first time, the complex web of links between physical and behavioral characteristics, like age, body mass index (BMI), and substance use, and specific patterns of brain structure and function in patients with psychosis. The study is important because many of these characteristics can be targeted clinically to improve brain health in these patients.
Aseem R. Shukla, MD, a pediatric urologist at Children’s Hospital of Philadelphia, along with several of his colleagues from around the world, have created an innovative program to help address urological needs in India. The team is specifically addressing bladder exstrophy, a complex, rare disorder that occurs during fetal development when the bladder does not form completely and drains onto the surface of the abdomen.
Medicare’s experimental mandatory bundled payment model for knee and hip replacements is more likely to yield cost savings when the surgeries are performed in larger hospitals that do more of these procedures, according to a study from the Perelman School of Medicine at the University of Pennsylvania. Non-profit and major teaching hospital status also appear to be associated with cost savings, the Penn Medicine analysis found.
Using data from 24,000 surveys, an international team of researchers led by Washington University in St. Louis' Olin Business School, finds that people working in customer-facing companies are happier than those removed from direct customer interaction. Even employees down the line in customer-facing companies, back in cubicles, are happier.
One in five teachers who were the victims of physical or verbal violence at their schools didn’t report the incidents to school administrators, according to a nationwide study.The results showed that significant minorities of teachers who experienced violence also didn’t tell their colleagues (14 percent) or family (24 percent).
Working with cells grown in the lab, Johns Hopkins researchers have identified a biochemical pathway that allows a structure within cells, called the Golgi apparatus, to combat stress caused by free radicals and oxidants. The research team showed that this pathway can be activated by a drug called monensin, which is commonly used as an antibiotic in animal feed.
Researchers at the University of Notre Dame found that the complexity of a uranium-based mineral, dubbed ewingite, is nearly twice as high as the previous most complex mineral.
New "smart glass" technology developed at the University of Delaware could make curtains and blinds obsolete. This isn't the first "smart glass," but it's one-tenth the price of other versions and more transparent in its transparent state and more reflective in its reflective state than competitors.
Researchers have discovered more details about the way certain materials hold a static charge even after two surfaces separate, information that could help improve devices that leverage such energy as a power source.
Letting the soil rest can be difficult economically for farmers. Researchers experimented with crop rotation and grazing to discover the least possible amount of time it would take to allow the soil to heal.
Researchers from St. Jude Children’s Research Hospital have discovered that inhibiting an enzyme called cyclin-dependent kinase 2 (CDK2) protects mice and rats from noise- or drug-induced hearing loss. The study, which will be published March 7 in the Journal of Experimental Medicine, suggests that CDK2 inhibitors prevent the death of inner ear cells, which has the potential to save the hearing of millions of people around the world.
In a collaborative, multi-institutional study published by JAMA Oncology, researchers from the University of Alabama at Birmingham, University of Chicago, and National Cancer Institute determined that MRI-based prediction models can help reduce unnecessary biopsies in suspected prostate cancer patients and help improve personalized risk stratification.
Fertilisers with lower environmental impacts and reduced costs for farmers are being developed by University of Adelaide researchers in the world-first use of the new advanced material graphene as a fertiliser carrier.
For the first time, researchers have linked radiation-damaged thyroid glands to poor surgical outcomes. The solution may be as simple as a common hormone supplement. Researchers at the University of Michigan have discovered a link between low thyroid hormone levels and wound healing complications. MORE FROM THE LAB: Subscribe to our weekly newsletter The retrospective study looked at 182 patients with laryngeal squamous cell carcinoma who were first treated with radiation, but ultimately required a total laryngectomy, or removal of the voice box.
A study of domestic violence victims finds that Hispanic women seek legal help more often than non-Hispanic white women, and the two groups have different reasons for remaining in abusive relationships.
New research from Arizona State University shows that using a 3-dimensional layer of Polydimethylsiloxane (PDMS) can mitigate dendrite formation and stands to both dramatically extend battery life and diminish safety risks.
Stigmas, attitudes of self-reliance and misattributing symptoms led a group of young adults experiencing their first episode of psychosis to delay seeking treatment, finds a new study from the Brown School at Washington University in St. Louis.
Compared to white Americans, African Americans are disproportionately affected by mental illnesses. New York University professor Norissa Williams found one healthcare model which can help change that and increase access and utilization of mental health services by African Americans. In a review published in the Best Practices in Mental Health journal, Williams found that integrating multiple sectors of care (e.g., primary care, behavioral health care, substance abuse services, etc.) into one health system is the best approach to providing African Americans with access to mental health care services.
Using data from a large ovarian cancer registry, a research team from Roswell Park Comprehensive Cancer Center uncovered a link between testicular cancer and familial ovarian cancer that may be attributable to genetic factors on the X chromosome.
A study of mouse healing after severe heart attacks focused on the heart and spleen, measuring types and numbers of immune cells; types and amounts of lipid signaling compounds; expression of enzymes that produce those signaling compounds; and which enzymes are key to resolution of inflammation.
Whether you pick low-carb, low fat or another diet plan, scientific research indicates each can help some people achieve modest long-term weight loss with potential improvement in health risks, according to the Scientific Statement the Endocrine Society issued today on managing obesity.
Federal researchers have discovered that severe stress or trauma early in life could actually change how the brain responds to stress hormones, essentially "re-wiring" the brain for later neuropathological disorders, according to a study, "A role for corticotrophin releasing factor signaling in the lateral habenula and its modulation by early life stress," published in Science Signaling, March 6.
Astronomers have used Hubble to uncover a vast, complex dust structure, about 150 billion miles across, enveloping the young star HR 4796A. A bright, narrow, inner ring of dust is already known to encircle the star and may have been corralled by the gravitational pull of an unseen giant planet. This newly discovered huge structure around the system may have implications for what this yet-unseen planetary system looks like around the 8-million-year-old star, which is in its formative years of planet construction.
There are many factors that account for Donald Trump’s 2016 presidential election victory, but Americans would be doing a disservice to their understanding of the country’s political system by ignoring Trump’s 14-year starring role as a reality television personality, according to an associate professor in the University at Buffalo Department of Psychology.
Shira Gabriel is lead author of a forthcoming study which is the first to scientifically examine how viewers’ parasocial bonds with Trump, formed through his television shows, “The Apprentice” and “The Celebrity Apprentice,” contributed to his being elected to the nation’s highest office.
SBP researchers have discovered that accumulation of ceramides—a type of lipid (fat)— plays a crucial role in lipotoxic cardiomyopathy (LCM)—a heart condition that often occurs in patients with diabetes and obesity. The study, published today in Cell Reports, also identified several potential therapeutic targets that could prevent or reverse the effects of LCM.
An interdisciplinary team of scientists at University of Utah Health are using animals' unique traits to pinpoint regions of the human genome that might affect health. The results of this project are available in the March 6 issue of the journal Cell Reports.
A new study conducted by researchers at The Wistar Institute revealed how a key protein residing in the endoplasmic reticulum (ER) helps cells respond to stress. This process is especially important for B cells to respond to severe stress conditions and their ability to produce antibodies. The research was published online in the Journal of Cell Biology.
A sizable percentage of elderly patients with blood-related cancers such as leukemia and multiple myeloma are apt to show signs of diminished cognitive functioning
Scientists at Washington University School of Medicine in St. Louis have used the gene-editing technology CRISPR to engineer human T cells that can attack human T cell cancers. The new approach also eliminates a dangerous side-effect called graft-versus-host disease.
A study at Hospital for Special Surgery (HSS) found a discrepancy between doctor reviews provided by hospital websites and those posted on independent physician rating websites such as Healthgrades.com and Vitals.com.
New research from The University of Texas at Dallas supports the growing consensus that pain begins differently for men and women at the cellular level.
Researchers have found strong evidence that environmental exposures, including air pollution, affect gene expressions associated with respiratory diseases much more than genetic ancestry. The study, published today in Nature Communications, analyzed more than 1.6 million data points from biological specimens, health questionnaires and environmental datasets, making this study one of the largest ever to examine the relationship between gene expression and environmental stimuli. These findings represent a groundbreaking use of big data to uncover the environmental factors that are behind diseases and inform strategies for prevention, an approach that would apply to a number of diseases, including cancer.
Researchers at the National University of Singapore have created a new platform with the potential to extract tiny circulating biomarkers of disease from patient blood. This simple, fast and convenient technique could help realize liquid biopsy diagnostics -- a less invasive procedure than the current gold standard: tumor biopsies. Details of the new technique, which utilizes standard laboratory equipment, are reported in this week's Biomicrofluidics.
Calcium ions enable cells to communicate with one another, allowing neurons to interact, muscles to contract, and the heart's muscle cells to synchronize and beat. To better understand these processes, researchers often use computer simulations, but accurate models are challenging and computationally expensive. In this week’s The Journal of Chemical Physics, researchers demonstrate how a straightforward modification in a computer model leads to highly accurate simulations, which serve as powerful tools for studying a range of biological processes.
While it may be the era of supercomputers and “big data,” without smart methods to mine all that data, it’s only so much digital detritus. Now researchers at the Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) and UC Berkeley have come up with a novel machine learning method that enables scientists to derive insights from systems of previously intractable complexity in record time.
Published in the journal Risk Analysis, the study, “Mitigating sports injury risks using Internet of Things and analytic approaches,” outlines how injury risk screening procedures can be administered using wireless devices, such as smartphones, connected to a cloud server. This connection between phones, computers and other devices is what researchers refer to as the Internet of Things. Athletic performance isn’t the only casualty of sports injuries. These injuries pose economic burdens on athletes and their families and can have long-lasting effects on an athlete’s quality of life. To help reduce the risk of injury, researchers at the University of Tennessee Chattanooga have developed a framework that measures an athlete’s risk of injury using Internet of Things (IoT) technology.
A new study from the University of Iowa finds firms headquartered in more religiously observant counties have higher credit ratings and lower debt costs, evidence that suggests lenders and bondholders consider the company’s culture when deciding whether to give them money.