Colorectal cancer is the second leading cause of cancer death for both men and women, according to the Centers for Disease Control and Prevention (CDC), even though 90 percent of people who are diagnosed through early testing can be cured.
Research on the relationship between the gut microbiome and diet can provide insights into diseases like depression and other health conditions.
Viruses are the most numerous biological entities on the planet. Now researchers at the Wellcome Sanger Institute and EMBL's European Bioinformatics Institute (EMBL-EBI) have identified over 140,000 viral species living in the human gut, more than half of which have never been seen before.
Researchers at University of California San Diego School of Medicine identified new therapeutic targets for gastrointestinal stromal tumors (GISTs) that could lead to new treatment options for patients.
Scientists from the Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago demonstrated that a nanotherapy reduces intestinal inflammation and shrinks lesions in a rodent model of severe Crohn’s disease. This approach could become an alternative to biologic antibody therapies that carry many side effects, including increased risk of certain cancers. It might also prevent the need for surgery in the future. Findings were published in the journal Advanced Therapeutics.
The February issue of The American Journal of Gastroenterology is now available and features new clinical research across a wide range of gastroenterology and hepatology topics, including inflammatory bowel disease, chronic viral hepatitis, biologics during pregnancy, colorectal cancer screening, GI symptoms in COVID-19, health inequities in patients with obesity, and more.
A new study by researchers at University of California San Diego School of Medicine found delayed time between abnormal stool-based screening and subsequent colonoscopy was associated with an increased risk of a cancer diagnosis and death from colorectal cancer.
GRAND RAPIDS, Mich. (Feb. 2, 2021) — What does bile acid production in the digestive tract have to do with Parkinson’s disease?
A surgical procedure meant to counter ulcerative colitis, an immune disease affecting the colon, may trigger a second immune system attack, a new study shows.
Probiotic Lactobacillus bacteria use enzymes situationally to manipulate bile acids and promote their own survival in the gut.
The prevalence of inflammatory bowel diseases has significantly increased both in Finland and globally.
Researchers at Washington University School of Medicine in St. Louis have found that patients with Barrett's esophagus may be vulnerable to coronavirus infection from what they swallow.
Drs. Armando Sardi, Vadim Gushchin, and Kurtis Campbell, Surgical Oncology Department at Mercy Medical Center, are regarded for their training and skills in utilizing HIPEC to treat advanced stages of abdominal cancer (peritoneal surface malignancies). New findings by a prestigious organization of clinicians adds to this reputation, placing Mercy’s program among the nation’s best.
Hackensack Meridian Mountainside Medical Group announced today that Rosemarie Arena, M.D., has joined the practice, expanding their gastroenterology group.
The January issue of The American Journal of Gastroenterology is now available and features new clinical research across a wide range of GI and hepatology topics, including NAFLD, colorectal cancer screening, GERD, post-COVID-19-associated functional GI disorder surges, celiac disease, and more.
Physicians have long known that necrotizing enterocolitis (NEC), a potentially lethal inflammatory condition that destroys a premature infant’s intestinal lining, is often connected to the development of severe brain injury in those infants who survive. However, the means by which the diseased intestine “communicates” its devastation to the newborn brain has remained largely unknown.
Researchers from The University of Texas MD Anderson Cancer Center who profiled more than 45,000 individual cells from patients with peritoneal carcinomatosis (PC), a specific form of metastatic gastric cancer, defined the extensive cellular heterogeneity and identified two distinct subtypes correlated with patient survival.
New study illustrates how studying diverse populations can help predict patient outcomes and reduce health disparities
Stupid Strong Charitable Foundation is proud to contribute $250,000 to The University of Texas MD Anderson Cancer Center to support cutting-edge research in gastric cancer led by Jaffer Ajani, M.D., professor of Gastrointestinal Medical Oncology.
The new guideline recommends is a positive diagnostic strategy involving a careful history, physical examination, and limited diagnostic testing, which can substantially shorten time to appropriate therapy and be more cost-effective for patients.
In PLOS Biology, a Stanford scientist ranked and published the top 2% of scientists (~150,000) from all fields of science based on their publication records, impact factor of the journal and the citation rates by other prominent investigators. Mercy’s Sergey V. Kantsevoy, M.D (top 0.5% in the world) and Paul J. Thuluvath, M.D (top 0.15% in the world) of The Institute for Digestive Health and Liver Disease (IDHLD) were noted among this 2% of all world scientists from all disciplines of science.
January 2021 DCR Journal videos
A study from researchers at Washington University School of Medicine in St. Louis has found that a toxin produced by E. coli changes intestinal cells to benefit itself, an ability that could provide a clue to why the bacteria have been linked to nutritional problems such as malnutrition and stunted growth.
An enzyme in the colon lining releases hydrogen peroxide – a known disinfecting compound- to protect the body from gut microbial communities. Findings from the UC Davis Health study points to importance of considering a different approach to treating gut inflammation and bacterial imbalance in the colon.
Henry Ford Health System is the first in the country to perform a procedure using the CG-100 intraluminal device, which is temporarily inserted into the gastrointestinal tract and designed to reduce diverting stoma rates, and the need for an ostomy bag, in patients undergoing gastrointestinal resection procedures due to colorectal cancer treatment.
The December issue of The American Journal of Gastroenterology is now available and features new clinical research across a wide range of gastroenterology and hepatology topics, including health disparities, colorectal cancer, cirrhosis, pediatric gastroenterology, the environmental impact of endoscopy, and more.
In children with autism, repetitive behaviors and gastrointestinal problems may be connected, new research has found. The study found that increased severity of other autism symptoms was also associated with more severe constipation, stomach pain and other gut difficulties.
A Rutgers study has discovered that vitamin D regulates calcium in a section of the intestine that previously was thought not to have played a key role. The findings have important implications on how bowel disease, including ulcerative colitis and Crohn’s disease, may disrupt calcium regulation.
New York University, Columbia University, and Takeda Pharmaceutical Company Limited (“Takeda”) have formed a collaborative research alliance to begin and advance gastroenterology research programs, with the goal of developing new therapies for patients with gastrointestinal and liver disorders.
Maria T. Abreu, M.D., a renowned gastroenterologist at the University of Miami Miller School of Medicine, was honored with the “Lifetime Disruptor” award at the American College of Gastroenterology’s 2020 virtual meeting.
Pancreatic cancer often is hidden and doesn't cause symptoms until it has spread. It is a leading cause of cancer deaths in the world. November 19 is World Pancreatic Cancer Day, but the entire month of November is meant to bring awareness to this disease. Advances in screening and early detection for high-risk people, minimally invasive surgical innovations and new genetic classifications are changing the outlook for pancreatic cancer, says Dr. Michael Wallace, a Mayo Clinic gastroenterologist.
Blood clots are the biggest cause of death in patients with inflammatory bowel disease (IBD) ─ ulcerative colitis or Crohn's disease. In a retrospective study recently published in the journal Gastroenterology, Cedars-Sinai investigators found that a combination of rare and common genetic variants in some IBD patients significantly increased their risk of developing clot-causing thromboembolic diseases.
An enzyme that helps COVID-19 (coronavirus) infect the body also plays a role in inflammation and patient outcomes in inflammatory bowel disease (IBD), according to a new study led by Cedars-Sinai. The findings raise the possibility that anti-inflammatory drug therapies for IBD may aid recovery from coronavirus.
DALLAS – Oct. 28, 2020 – Mice fed diets high in sugar developed worse colitis, a type of inflammatory bowel disease (IBD), and researchers examining their large intestines found more of the bacteria that can damage the gut’s protective mucus layer.
The American College of Gastroenterology (ACG) announces the winners of the 2020 SCOPY Awards (Service Award for Colorectal Cancer Outreach, Prevention, and Year-Round Excellence) to recognize the achievements of ACG members in their community engagement, education and awareness efforts for colorectal cancer prevention.
David A. Greenwald, MD, FACG, a gastroenterologist and the Director of Clinical Gastroenterology and Endoscopy at Mount Sinai Hospital in New York City, was elected by the membership as the 2020–2021 President of the American College of Gastroenterology (ACG), a national medical organization representing more than 15,000 clinical gastroenterologists and other specialists in digestive diseases.
More than 7,000 gastroenterologists and other health care professionals so far will convene virtually for the premier clinical gastroenterology event—the American College of Gastroenterology’s 85th Annual Scientific Meeting and Postgraduate Course (Virtual ACG 2020)—to review the latest scientific advances in gastrointestinal research, treatment of digestive diseases, and clinical practice management.
A personalized program to increase resilience in patients with inflammatory bowel disease (IBD) can substantially reduce hospitalizations and emergency room visits, Mount Sinai researchers report. The research is being unveiled on October 27th in a plenary presentation at the annual scientific meeting of the American College of Gastroenterology (ACG 2020).
An international team of researchers led by McMaster University has found that tryptophan, an amino acid present in high amounts in turkey, along with some probiotics, may help them heal and respond better to a gluten-free diet. The findings highlight the potential therapeutic value of targeting tryptophan metabolism in the gut in celiac disease to better control symptoms, despite the gluten-free diet, and accelerate intestinal healing.
Colon cancer is on the rise, especially among younger age groups and prompt diagnosis is key to improving chance of survival. Sameet Shah, M.D., gastroenterologist of Hackensack Meridian Mountainside Medical Group, shares his knowledge to educate patients on the signs and symptoms of colon cancer and how to prevent it best.
DALLAS – Oct. 7, 2020 – Endocannabinoids, signaling molecules produced in the body that share features with chemicals found in marijuana, can shut down genes needed for some pathogenic intestinal bacteria to colonize, multiply, and cause disease, new research led by UT Southwestern scientists shows.
Deirdre J. Cohen, MD, MS, an expert in pancreatic and other gastrointestinal cancers as well as an accomplished clinical trial leader has joined Mount Sinai Health System as Director of the Gastrointestinal (GI) Oncology Program and Medical Director of the Cancer Clinical Trials Office at The Tisch Cancer Institute.
UC San Diego School of Medicine researchers reported that genetic testing is cost-effective and beneficial for newly diagnosed patients with metastatic gastrointestinal stromal tumors (GIST), a rare type of cancer.
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