A newly published Atopic Dermatitis (AD) Yardstick from the American College of Allergy, Asthma and Immunology has practical recommendations for physicians about the treatment of AD.
UCR study shows how intensive pesticide use is driving mosquito evolution at the genetic level
Researchers at the University of Georgia have now shown that the enzyme that makes the El Tor family of V. cholerae resistant to those antibiotics has a different mechanism of action from any comparable proteins observed in bacteria so far. Understanding that mechanism better equips researchers to overcome the challenge it presents in a world with increasing antibiotic resistance. The results of this research are published in the Dec. 22, 2017 issue of the Journal of Biological Chemistry.
As flu season swings into high gear, a new poll suggests nursing homes and other long-term care facilities should be doing more to get their staff and patients vaccinated before it’s too late. Nearly three-quarters of people over age 50 say all staff in such facilities should definitely be required to get the flu vaccine. More than 60 percent say that patients should definitely get vaccinated too.
Working with a simple mathematical model in which chance plays a key role, researchers Steve Strogatz and Bertrand Ottino-Loofler calculated how long it would take a bacterial infection or cancer cell to take over a network of healthy cells. The distribution of incubation times in most cases, they contend, is close to “lognormal” – meaning that the logarithms of the incubation periods, rather than the incubation periods themselves, are normally distributed.
Mount Sinai researchers have discovered that normal immune cells called macrophages, which reside in healthy breast tissue surrounding milk ducts, play a major role in helping early breast cancer cells leave the breast for other parts of the body, potentially creating metastasis before a tumor has even developed, according to a study published in Nature Communications.
Through gene therapy, researchers engineered blood-forming stem cells (hematopoietic stem/progenitor cells, or HSPCs) to carry chimeric antigen receptor (CAR) genes to make cells that can detect and destroy HIV-infected cells. These engineered cells persisted for more than two years
Antibiotics could become nearly useless by mid-century against intense infections due to bacteria evolving antibiotic resistance. And alternatives haven't been able to replace them. It's time for a rethink: Try reducing antibiotic use for small infections and find alternate treatments for them. Save antibiotics for the big infections.
Holiday travel forces people into often-crowded airplanes, automobiles and airports and the result can be a cold or other bug that dims the holiday cheer.
The development of an HIV vaccine has proven extraordinarily difficult. One of the reasons is that naïve precursor B cells that can give rise to mature B cells producing broadly neutralizing antibodies are exceedingly rare within the average human. Yet, despite their low frequency these B cell precursors can outcompete their B cell competitors under the right conditions.
A class of anti-inflammatory drugs already FDA-approved for rheumatoid arthritis could “purge” the reservoir of infected immune cells in people infected by HIV, according to new research.
The Sbarro Health Research Organization congratulates the Italian researchers who were able to prove a direct causal link between the infection by Xylella fastidiosa and the death of olive trees in southern Italy.
When viruses infect the body’s cells, those cells face a difficult problem. How can they destroy viruses without harming themselves? Scientists at University of Utah Health have found an answer by visualizing a tiny cellular machine that chops the viruses’ genetic material into bits.
Researchers at the Duke Human Vaccine Institute have led an effort to develop a more accurate way to gauge the incidence of HIV infections in large populations, which will improve research and prevention strategies worldwide.
A Lawrence Livermore National Laboratory biomedical technology that can deliver vaccines and drugs inside the human body has been licensed for use in cancer treatments to a Michigan company.
The findings point the way to targeting diseases where this protein is mutated.
A virologist involved in the debate over "gain of function" and dual-use infectious disease research reflects on the issue, in the wake of NIH action.
In Shortsville, New York, about 30 miles east of Rochester, reindeer brothers Moose and Little Buddy call a little farm home. Their owner, Mike Schaertl, was looking forward to Little Buddy’s first holiday season, but last month the 5-month-old reindeer got very sick.
The American Cleaning Institute (ACI)welcomed a decision by the Food and Drug Administration to defer rulemaking on critically important ingredients used in healthcare antiseptic products, including soaps, hand washes and rubs.
A study in The Journal of Pediatrics by researchers at Université de Montréal reveals that sexual assault on children leads to an increase in genitourinary health problems in girls, but not boys.
Understanding that divergence, University of Notre Dame researchers say, is a starting point to determining whether there are non-biting genes in other species that could be manipulated in order to reduce transmission of vector-borne diseases.
Nearly a century after the influenza pandemic of 1918–1919 ravaged communities worldwide, the threat of another pandemic looms large as the scientific and global health communities find ways to prepare for, and battle, future outbreaks.
Researchers have found genetic explanations for why most mosquitoes in one species favor nectar over blood. This work could one day lead to strategies to prevent mosquito-borne illness.
An international group of researchers have designed new anti-viral nanoparticles that bind to a range of viruses, including herpes simplex virus, human papillomavirus, respiratory syncytial virus and Dengue and Lentiviruses. Unlike other broad-spectrum antivirals, which simply prevent viruses from infecting cells, the new nanoparticles destroy viruses.
It’s easy to get worn down this time of year. A Michigan Medicine expert offers tips to handle holiday travel with your health in mind.
Moving the Office of Global AIDS Coordinator, which oversees and manages PEPFAR, out of the U.S. State Department would likely provide little benefit and could have a profoundly negative impact on its ability to effectively lead the global fight against HIV/AIDS, concludes a report with input from leading global health experts and former officials from both Republican and Democratic administrations.
Microscopes enhanced with artificial intelligence (AI) could help clinical microbiologists diagnose potentially deadly blood infections and improve patients’ odds of survival, according to microbiologists at Beth Israel Deaconess Medical Center (BIDMC).
Researchers at The Johns Hopkins University report statistical evidence that children exposed to airborne coarse particulate matter — a mix of dust, sand and non-exhaust tailpipe emissions, such as tire rubber — are more likely to develop asthma and need emergency room or hospital treatment for it than unexposed children.
Men infected with HPV16, the type responsible for most HPV-related cancers, are 20 times more likely to be reinfected with the same type of HPV after one year. That is according to a new study published this month in the Proceedings of the National Academy of Sciences. The article shows the same effect in both men who are sexually active and celibate, suggesting that they are not reacquiring the virus from another sexual partner.
Indiana University School of Medicine researchers have identified a way to block the ability of parasites that cause malaria to shield themselves against drug treatments in infected mice—a finding that could lead to the development of new approaches to combat this deadly disease in humans.
Survivors of the first known Ebola outbreak, which occurred in the Democratic Republic of the Congo in 1976, may be key to development of vaccines and therapeutic drugs to treat future outbreaks
Research from the Monell Center documented wide individual differences to the taste of the life-saving HIV medication Kaletra and identified genetic sources of the taste variation. The findings suggest that the growing field of pharmacogenetics should assess the sensory response to medicines to promote medication compliance and treatment success.
Monkeys who catch Zika virus through bites from infected mosquitoes develop infections that look like human Zika cases, and may help researchers understand the many ways Zika can be transmitted.
Lyme bacteria can survive a 28-day course of antibiotic treatment four months following infection by tick bite, according to a new study using a primate model for the disease. Despite testing negative for Lyme disease, some subjects were infected with Lyme bacteria in heart, brain and other organs.
In the wild, chimpanzees face any number of dire threats, ranging from poachers to predators to deforestation. That’s why scientists, investigating an outbreak of respiratory disease in a community of wild chimpanzees in Uganda’s Kibale National Park, were surprised and dismayed to discover that a human “common cold” virus known as rhinovirus C was killing healthy chimps.
Men who have never engaged in sexual intercourse are still at risk for acquiring HPV, according to a study published recently in the Journal of Infectious Diseases by researchers at The University of Texas Health Science Center at Houston (UTHealth) School of Public Health.
A team of researchers working across disciplines and universities is developing a flu nanovaccine that preliminary studies suggest could be more effective than today's seasonal shots. The NIH is supporting the research with a five-year, $2.8 million grant.
Lactic acid bacteria, commonly used as probiotics to improve digestive health, can offer protection against different subtypes of influenza A virus, resulting in reduced weight loss after virus infection and lower amounts of virus replication in the lungs, according to a study led by Georgia State University.
Researchers at Duke Health are working to expand the medical toolkit for treating Lyme disease by identifying vulnerable areas of the disease-causing bacterium that could lead to innovative therapies.
Despite the fact that their disease may be more severe, a new study shows minorities are less likely than white Americans to see a doctor for psoriasis treatment. Researchers from the Perelman School of Medicine at the University of Pennsylvania found that black, Asian, and other non-Hispanic minorities are about 40 percent less likely to see a dermatologist for psoriasis than whites.
Michigan Medicine is among the first recipients to receive the Antimicrobial Stewardship Centers of Excellence designation from the Infectious Diseases Society of America.
Chickenpox is a highly contagious disease caused by a virus. Although the incidence of chickenpox has declined significantly since the development of the chickenpox vaccine, there are still children who develop chickenpox every year, say dermatologists from the American Academy of Dermatology. Fortunately, there is a lot parents can do at home to help ease their children’s symptoms.
NAU researcher Jeff Foster led the team of international scientists who tried to definitively answer several questions—where did this fungus come from? And more importantly, can a resistance be evolved?
Toxic Chemicals in Salons, Lack of Education Lead to Adverse Health Effects
Research from the University of Illinois at Chicago suggests bond duration, not bond tightness, may be the most important differentiator between antibiotics that kill bacteria and antibiotics that only stop bacterial growth.
An alternative animal model that mimics key features of the Zika virus infection, including its lingering presence in bodily fluids, has been developed at Texas Biomedical Research Institute in San Antonio.
Although the insidious bacterium Salmonella typhi has been around for centuries, very little is actually known about its molecular mechanisms. A new study from researchers at the College of Veterinary Medicine addresses this knowledge gap and may lead to novel, targeted treatments.
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