An Independent Panel formed to review the U.S. Department of Health and Human Service’s response to Ebola calls for increased coordination both within HHS and across all involved federal agencies and strengthened coordination and collaboration with state and local governments and their private-sector partners.
With mosquito season underway, SLU vaccine researchers have received NIH funding to study the body’s immune response to Zika.
The Center for Vaccine Development (CVD) has been awarded a large grant for research that will help determine why so many children under five are dying in the world’s poorest countries. The grant will fund use of an innovative alternative to traditional autopsy known as minimally invasive tissue sampling.
NIBIB-funded scientists used computers to model the formation of tuberculosis granulomas in the lung -- the non-active (latent) form of infection found in 2 billion individuals worldwide (11 million in the U.S.) that can activate to become a life-threatening infection. Employing a computer model aims to speed analysis of TB’s complex life-cycle and to identify potential new antibiotics, antibiotic targets, and biomarkers that can predict transition to active infection.
High mosquito and human population densities, combined with mosquito breeding conditions, are the central cause for Zika virus.
Led by Claudio Soto, Ph.D., researchers from McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth) have been awarded $11 million from the NIAID to study the pathogenesis, transmission and detection of prion diseases – such as chronic wasting disease in deer – that can potentially spread to humans.
Big data has a bright future in personalized medicine, as demonstrated by an international competition centered at Rice University that suggested ways forward for treatment of patients with leukemia.
Researchers have identified immune cells vital for protecting us from potentially fatal C. difficile infection. Surprisingly, those cells are often vilified for their role in causing asthma and allergies. But when it comes to C. difficile, they could be the difference in life and death.
Chemists at The Ohio State University are developing paper strips that detect diseases including cancer and malaria—for a cost of 50 cents per strip.
Two new studies led by scientists at The Scripps Research Institute advance efforts to produce HIV vaccine candidates, potentially suitable for large-scale production.
University of Wisconsin–Madison researchers studying monkeys have shown that one infection with Zika virus protects against future infection, though pregnancy may drastically prolong the time the virus stays in the body.
The rapid development of a safe and effective vaccine to prevent the Zika virus (ZIKV) is a global priority, as infection in pregnant women has been shown to lead to fetal microcephaly and other major birth defects. The World Health Organization declared the Zika virus epidemic a global public health emergency on February 1, 2016.
Policy makers’ and public health officials’ proper reactions could hold down the total costs to U.S. GDP of an influenza outbreak. Otherwise, costs could be nearly double previous estimates.
Case Western Reserve University School of Medicine experts and colleagues in the United States and Africa have received an $11 million, five-year NIH grant to understand why some people living with HIV in Africa avoid becoming infected with the bacterium that causes tuberculosis (TB) despite exposure to high-TB-risk circumstances.
Recent studies on a small number of patients with leukemia treated with bone marrow transplantation have suggested that the presence of the common cytomegalovirus (CMV) in patients or their donors may protect against relapse or even death after the transplant. A large international study published in the journal Blood now shows the opposite. The virus not only does not prevent leukemia relapse, but also remains a major factor associated with the risk of death.
The Perelman School of Medicine at the University of Pennsylvania and The Children’s Hospital of Philadelphia have been awarded over $5 million to serve as a U.S. Centers for Disease Control and Prevention (CDC) Prevention Epicenter site to help develop and test innovative approaches to preventing superbugs and improving patient safety.
The 2009 swine H1N1 flu pandemic — responsible for more than 17,000 deaths worldwide — originated in pigs from a very small region in central Mexico, a research team headed by investigators at the Icahn School of Medicine at Mount Sinai is reporting.
Researchers at Johns Hopkins have found that an old drug once mostly used to treat amebiasis — a disease caused by a parasite — and induce vomiting in cases of poisoning appears to also halt replication of cytomegalovirus (CMV), a herpesvirus that can cause serious disease in immunocompromised individuals, including those with HIV or organ transplant recipients.
Handheld, mobile phone-based microscopes can be used in developing countries after minimal training of community laboratory technicians to diagnose intestinal parasites quickly and accurately.
If the United States responds to Zika the way it did to Ebola—and early indications are that in many ways it is—the country can expect missteps brought about by a lack of health care coordination and a lot of political finger pointing, according to an analysis by the University of Michigan.
A team of scientists has uncovered the global, evolving, and historic make-up of Plasmodium vivax, one of the five species of malaria that infect humans. The research, which links the spread of the parasite back to colonial seafaring, among other phenomena, underscores the challenges health experts face in controlling the parasite.
Kansas State University is helping the fight against Zika virus through mosquito research at the Biosecurity Research Institute.
UAlberta scientists study compounds with anti-prion properties to address rare but fatal diseases.
Before your family heads to Mexico, Asia or beyond, do a little planning ahead of time to keep everyone healthy during their journey. Dr. Nava Yeganeh, an assistant professor of pediatric infectious diseases and director of the Pediatric International Travel and Adoption Clinic at Mattel Children’s Hospital UCLA, explains three important strategies.
A group of Western Illinois University student and faculty researchers are spending the summer conducting surveillance of tick-borne diseases and mosquito-borne arboviruses in regional counties.
Pregnant women in Latin American countries were more likely to seek an abortion after receiving health alerts about Zika virus, according to a study co-authored by Princeton University researchers and published in the New England Journal of Medicine.
What used to take several weeks is now possible in two days: thanks to new molecular-based methods, mycobacterial pathogens that cause pulmonary infections or tuberculosis can now be detected much more quickly. Time-consuming bacteria cultures no longer need to be taken from the patient samples, meaning that a suitable therapy can be started quickly.
The American Mosquito Control Association’s annual National Mosquito Control Awareness Week aims to educate about the significance of mosquitoes and the importance of eliminating them. Amy Lawhorne, vice president and brand leader at Mosquito Squad, the largest and most experienced home and commercial mosquito control firm in the country, is putting mosquitoes on notice.
Saint Louis University's vaccine center has been tapped by the National Institutes of Health to conduct a human clinical trial of a vaccine to prevent the Zika virus, which can cause devastating birth defects in babies.
Previous exposure to the dengue virus may increase the potency of Zika infection, according to research from Imperial College London.
RTI International will serve as the data coordinating center for a multi-country study to evaluate the magnitude of health risks that Zika virus infection poses to pregnant women and their developing fetuses and infants. The study is led by the National Institutes of Health and Fundacao Oswaldo Cruz-Fiocruz.
Certain viruses, such as influenza, could survive on children’s toys long enough to result in exposures, placing children at risk for getting infectious diseases, according to researchers at Georgia State University.
Go here for the latest research, experts and features on Zika in the Zika Virus News Source
Many West Nile encephalitis survivors suffer long-term neurological problems such as memory loss. New research from Washington University School of Medicine shows that the patients’ own immune systems may have destroyed parts of their neurons, and that intervening in the immune response may help.
Johns Hopkins University engineering students working to develop a better suit to protect health care workers in Ebola outbreaks have developed prototypes for a more comfortable hood and face mask that make breathing easier, and for a battery-powered system that curbs humidity in the suit.
By studying the fruit fly, Kansas State University researchers have found a connection between a gene called clueless and genes that cause Parkinson's disease.
The transmission of Taenia solium, a pork tapeworm species that infects humans and causes late-onset seizures and epilepsy, can be stopped on a population-wide level with mass treatments of both pigs and humans, researchers have shown.
In the following Q&A, Richard Duhrkopf, Ph.D., associate professor of biology in Baylor’s College of Arts & Sciences and nationally recognized expert on mosquitoes, provides an update on national and statewide (Texas) efforts and gives tips to avoid mosquitoes known to carry Zika (Aedes aegypti and Aedes albopictus), which, he said, are different from those that carry other viruses such as West Nile.
Multicenter, phase II trial suggests autologous transplant should be standard of care for HIV patients with relapsed/treatment-resistant lymphoma.
CHAPEL HILL, NC — With no laboratory test available to diagnose functional gastrointestinal disorders, proper diagnostic criteria are critical for clinicians to make an accurate determination of what ails their patients. Several University of North Carolina School of Medicine researchers played a key role in crafting diagnostic criteria and patient questionnaires for the Rome Foundation, an international nonprofit aimed at improving the lives of the millions of people suffering from functional GI disorders (FGIDs), while developing and legitimizing the field of FGIDs through science and research.
Mosquito bite sites are not just itchy, irritating nuisances - they also make viral infections spread by the insects far worse, new research has found.
The U.S. Food and Drug Administration has approved initiation of the first phase I human trial for a Zika vaccine, based on new research with key findings generated in the lab of David B. Weiner, Ph.D., executive vice president, director of the Vaccine Center, and the W.W. Smith Endowed Chair in Cancer Research at The Wistar Institute.
Three Pioneering Scientists Recognized for Breakthroughs in Astrophysics, Organic Chemistry, and Molecular Biology.
New research has discovered peptides from two crop species that have antimicrobial effects on bacteria implicated in food spoilage and food poisoning They are similar in structure to a human peptide used to guard against beer-spoiling bacteria
UT institutions have discovered ways to clone Zika, kill with with algae and link it to brain cells destined to become neurons.
Using tiny, alpaca-derived, single-domain antibody fragments, Whitehead Institute scientists have developed a method to perturb cellular processes in mammalian cells, allowing them to tease apart the roles that individual proteins play in these pathways. With improved knowledge of protein activity, scientists can better understand not only basic biology but also how disease corrupts cellular function and identify potential therapeutics to rectify these aberrations.
A team at Washington University School of Medicine in St. Louis has identified a single gene pathway that is vital for Zika and other flaviviruses to spread infection between cells. Further, they showed that shutting down a single gene in this pathway — in both human and insect cells — does not negatively affect the cells themselves and renders flaviviruses unable to leave the infected cell, curbing the spread of infection.
Rift Valley fever virus and other bunyaviruses may soon be added to the list of viruses denied access to a human host. Sandia National Laboratories researchers have discovered a mechanism by which RVFV hijacks the host machinery to cause infection
What if private companies could obtain some coverage to protect their foreign investments in developing countries against crippling infectious disease outbreaks such as Ebola? The possible path to offering disease outbreak guarantees is an idea being posed by two global health researchers who suggest that a mechanism for establishing such an instrument could be tied to public health investments.
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