Picky eating among children is a common but burdensome problem that can result in poor nutrition for kids, family conflict, and frustrated parents. Although many families see picky eating as a phase, a new study from Duke Medicine finds moderate and severe picky eating often coincides with serious childhood issues.
A new blood test could help emergency room doctors quickly diagnose traumatic brain injury and determine its severity. The findings, published July 10 in the Journal of Neurotrauma, could help identify patients who might benefit from extra therapy or experimental treatments.
A recent HIV vaccine trial testing the HIV envelope as an immunogen was unsuccessful for protection against HIV infection. A new study has found that this vaccine selectively recruited antibodies reactive with both the HIV envelope and common intestinal microbes — a phenomenon previously reported by the same investigators to occur in the setting of acute HIV infection.
In a global study of drought impacts, forest trees took an average of two to four years to resume normal growth rates, a revelation indicating that Earth's forests are capable of storing less carbon than climate models have assumed.
Five men with complete motor paralysis were able to voluntarily generate step-like movements thanks to a new strategy that non-invasively delivers electrical stimulation to their spinal cords, according to a new study funded in part by the National Institutes of Health.
Virginia Commonwealth University Massey Cancer Center researchers at the VCU Center for the Study of Tobacco Products (CSTP) have developed the first ever, evidence-based model that can predict with up to 90 percent accuracy the amount of nicotine emitted by an electronic cigarette (e-cigarette).
Researchers at the University of Utah School of Medicine report that a nuanced, targeted version of parental control over gene expression, is the method of choice over classic genomic imprinting. Published in Cell Reports, so-called noncanonical imprinting is particularly prevalent in the brain, and skews the genetic message in subpopulations of cells so that mom, or dad, has a stronger say. The mechanism can influence offspring behavior, and because it is observed more frequently than classic imprinting, appears to be preferred.
Health experts have warned for years that the overuse of antibiotics is creating “superbugs” able to resist drugs treating infection. Now scientists at Indiana University and elsewhere are finding evidence that an invisible war between microorganisms may also be catching humans in the crossfire.
Using a hybrid silica sol-gel material and self-assembled monolayers of a common fatty acid, researchers have developed a new capacitor dielectric material that provides an electrical energy storage capacity rivaling certain batteries, with both a high energy density and high power density.
An innovative three-month elective course has helped make some first-year medical students at Albert Einstein College of Medicine more confident about dealing with health disparities they’ll likely encounter as physicians, according to a follow-up study published online today in the journal Academic Medicine.
Older Americans receive prescriptions for mental health drugs at more than twice the rate that younger adults do, but they’re much less likely to be getting their mental health care from a psychiatrist, a new study shows. Some seniors could be at risk of problems caused interactions between drugs.
The proposed studies are designed to test whether nonviral gene delivery into the oral cancer could be used to treat cancer pain effectively and safely.
Periodic telephone counseling can be a highly effective, low-cost tool for lowering blood-sugar levels in minority, urban adults with uncontrolled diabetes. The findings are the result of a clinical trial led by researchers at Albert Einstein College of Medicine and their collaborators at the New York City Department of Health and Mental Hygiene (Health Department). The study published online today in the American Journal of Preventive Medicine.
Article in journal Bioinformatics from University of Colorado Cancer Center describes a new tool that improves the ability to match drugs to disease: the Kinase Addiction Ranker (KAR) predicts what genetics are truly driving the cancer in any population of cells and chooses the best “kinase inhibitor” to silence these dangerous genetic causes of disease.
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have been awarded $1.4 million from the National Institute of Mental Health of the National Institutes of Health (NIH) to explore the development of drug candidates for a wide range of conditions, including circadian rhythm disorders.
Facial motion capture – the same technology used to develop realistic computer graphics in video games and movies – has been used to identify differences between children with childhood apraxia of speech and those with other types of speech disorders, finds a new study by NYU’s Steinhardt School of Culture, Education, and Human Development.
Researchers at Children’s Hospital Los Angeles and The Saban Research Institute of CHLA created a dynamic functional mouse model for lung injury repair, a tool that will help scientists explain the origins of lung disease and provide a system by which new therapies can be identified and tested.
Published today in Cancer Discovery, results of LOXO-101 against TRK fusion cancer confirm that stage IV patient's tumors had substantially regressed. With four months of treatment, additional CT scans demonstrated almost complete disappearance of the largest tumors.
Researchers at the National Institutes of Health have discovered a protein that plays a vital role in healthy egg-sperm union in mice. The protein RGS2 can delay an egg’s development into an embryo in order to allow time for sperm to arrive and merge with the egg in a healthy fertilization process. The embryo cannot survive without the male chromosomes.
With the decline of the development of new antibiotics due to the complexity and expense of discovering them, there has been a rapid growth of antibiotic resistant pathogens that is one of the leading causes of death. With the help of a nearly $4.9 million, 5-year grant from the National Institute for Allergy and Infectious Diseases of the National Institutes of Health, Wayne State University School of Medicine researchers are leading a landmark multi-center, international study that will provide essential information to clinicians for use of polymoxin B in critically ill patients where no other treatments will work.
Scientists uncover a port of liver entry for malaria parasites, and if these results hold up in humans, drugs that target this entry protein might help prevent the spread of disease.
Immune cells that hang around after parasitic skin infection help ward off secondary attack. These skin squatters may prove to be the key to successful anti-parasite vaccines.
Researchers at the University of Georgia College of Veterinary Medicine will lead a collaborative four-year study aimed at understanding the neurological mechanisms responsible for changes in taste following Roux-en-Y gastric bypass surgery and also diet-induced obesity.
Scientists from the Florida campus of The Scripps Research Institute have been awarded nearly $1.5 million from the National Institute of General Medical Sciences to explore the therapeutic potential of a class of proteins that play essential roles in the regulation and maintenance of human health.
Coating the inside of glass microtubes with a polymer hydrogel material dramatically alters the way capillary forces draw water into the tiny structures, researchers have found. The discovery could provide a new way to control microfluidic systems, including popular lab-on-a-chip devices.
Looking at measurements of the vertebrae – the series of small bones that make up the spinal column – in newborn children, investigators at Children’s Hospital Los Angeles found that differences between the sexes are present at birth.
New research indicates that adults born very premature are more likely to be socially withdrawn and display signs of autism.
A Vanderbilt research team has successfully created a mechanical wrist less than 1/16th of an inch thick -- small enough to use in needlescopic surgery, the least invasive form of minimally invasive surgery.
A new study from researchers at Beth Israel Deaconess Medical Center (BIDMC) compared open surgical repair of abdominal aortic aneurysm with a catheter-based procedure and found that the less invasive endovascular aortic repair has clear benefits for most patients, providing both a safer operation and a quicker recovery.
The brain’s effect on other parts of the body has been well established. Now, a group that includes two University of Florida Health researchers has found that it’s a two-way street: Body fat can send a signal that affects the way the brain deals with stress and metabolism.
In their bid to find the best combination of therapies to treat anaplastic thyroid cancer (ATC), researchers on Mayo Clinic’s Florida campus demonstrated that all histone deacetylase (HDAC) inhibitors are not created equal.
The algorithm ENVE could be the Google for genetic aberrations — and it comes from Case Western Reserve. The findings about the algorithm that distinguishes “noise” from real evidence, as well as some genetic characteristics of colon cancer in African Americans, appears this week in Genome Medicine.
Like a collection of ragtag villagers fighting off an invading army, the mix of bacteria that live in our guts may band together to keep dangerous infections from taking hold, new research suggests. But some “villages” may succeed better than others at holding off the invasion, because of key differences in the kinds of bacteria that make up their feisty population.
Despite heightened awareness of surveillance tactics and privacy breaches, existing computer security tools aren't meeting the needs of journalists working with sensitive material, a new UW study finds.
In a survey of a diverse group of almost 250 young, low-income, inner-city pregnant and postpartum women, Johns Hopkins researchers have learned that more than 90 percent use smartphones or regular cellphones to give and get information.
A paper published today in the Proceedings of the National Academy of Sciences argues against the commonly held "accumulation of mutations" model of oncogenesis in favor of a model that depends on evolutionary pressures acting on populations of cells.
Although the causes of many age-related diseases remain unknown, oxidative stress is thought to be the main culprit. Oxidative stress has been linked to cardiovascular and neurodegenerative diseases including diabetes, hypertension and age-related cancers. However, researchers at the University of Missouri recently found that aging actually offered significant protection against oxidative stress. These findings suggest that aging may trigger an adaptive response to counteract the effects of oxidative stress on blood vessels.
Only one in three older Americans have their diabetes under control as measured by guidelines set by the American Diabetes Association, new Johns Hopkins Bloomberg School of Public Health research suggests.
Johanna Olson, MD, and her colleagues at Children’s Hospital Los Angeles, provide care for the largest number of transyouth in the U.S. and have enrolled 101 patients in a study to determine the safety and efficacy of treatment that helps patients bring their bodies into closer alignment with their gender of identity.
Individuals with new-onset type 1 diabetes who took two courses of alefacept (Amevive®, Astellas Pharma Inc.) soon after diagnosis show preserved beta cell function after two years compared to those who received a placebo.
A new drug acts as a roadblock for malaria, curing mice of established infection, according to researchers. Treatment was not associated with obvious side effects, suggesting that the drug may also be safe and effective in humans.
Using existing drugs, such as lithium, to restore basic biological processes in human cells and animal models, researchers may have broken a long-standing logjam in devising effective treatments for human mitochondrial diseases.
Anyone who’s ever noticed a water puddle drying in the sun has seen an environment that may have driven the type of chemical reactions that scientists believe were critical to the formation of life on the early Earth.
A research team out of Michigan Tech has found a way to solve one of the biggest challenges of making metamaterials. Their optical work is a big step towards creating a "perfect lens".
A research team funded by the National Institutes of Health has generated a novel system for growing cardiac tissue from undifferentiated stem cells on a culture plate. This heart on a chip is a miniature physiologic system that could be used to model early heart development and screen drugs prescribed during pregnancy. Researchers from the University of California (UC) Berkeley; the Gladstone Institutes, in San Francisco; and UC San Francisco, reported their work in the July 14, 2015, online issue of Nature Communications.
Scientists at The Scripps Research Institute Florida campus have been awarded a pair of grants totaling nearly $2.8 million to develop a new therapeutic agent to reduce latent levels of HIV that hide from the immune system in infected individuals.
A new study suggests people who speak two languages have more gray matter in the executive control region of the brain.
Hospitalizations for heart conditions, neurological illness, and other conditions were higher among people who live near unconventional gas and oil drilling (hydraulic fracturing), according to new research.
Since 2007, clinical trials using gene therapy have resulted in often-dramatic sight restoration for dozens of children and adults who were otherwise doomed to blindness. Now, researchers have found evidence that this sight restoration leads to strengthening of visual pathways in the brain.
Peter Lichtenberg, Ph.D., director of the Institute of Gerontology at Wayne State University, won the Judge Edward Sosnick Courage to Lead Award for his extensive work to create ways of identifying older adults at risk of financial exploitation. The award is presented annually by the Oakland County SAVE (Serving Adults who are Vulnerable and/or Elderly) Task Force.
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