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Medicine

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Hematology, Blood Cancer, Mayo Clinic Cancer Center, Multiple Myeloma

Mayo Clinic Study Shows That Choice of Medical Center Impacts Life Expectancy of Multiple Myeloma Patients

ROCHESTER, Minn. – People diagnosed with multiple myeloma are more likely to live longer if they are treated at a medical center that sees many patients with this blood cancer. Mayo Clinic researchers published these findings today in the Journal of Clinical Oncology.

Medicine

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High Blood Pressure, Hypertension, cognitive abilities, dimentia

High Blood Pressure Can Impair Cognitive Function, Pose Risk for Alzheimer’s

High blood pressure in middle age can lead to impaired cognition and is a potential risk factor for Alzheimer’s disease.

Science

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St. Jude Children's Research Hospital, Pediatric Cancer Genome Project, Acute Lymphoblastic Leukemia, Genomics, B-precursor acute lymphoblastic leukemia, All

Genetic Hallmarks of Acute Lymphoblastic Leukemia Subtype Uncovered

St. Jude Children’s Research Hospital – Washington University Pediatric Cancer Genome Project team identifies genetic changes underlying a type of B-precursor acute lymphoblastic leukemia

Medicine

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Medicine, Hematology, Blood, Blood Transfusions, Clinical Trial, Healthcare

International Study Proves Old Blood Is as Good as New

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It’s been long thought that when blood transfusions are needed, it may be best to use the freshest blood, but McMaster University researchers have led a large international study proving that it is not so.

Medicine

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Johns Hopkins, Kimmel Cancer Center, Barbara Slusher, Jonathan Powell, Jonathan David Powell, Jonathan D. Powell, Cancer, Brain, Blood, 6‑diazo-5-oxo‑L‑norleucine, don

Scientists Build a Better Cancer Drug to Pass Through Blood-Brain Barrier

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In efforts to develop new treatments for brain cancer, scientists from Johns Hopkins Drug Discovery and the Kimmel Cancer Center's Bloomberg~Kimmel Institute for Cancer Immunotherapy report they have altered the structure of an experimental drug that seems to enhance its ability to slip through the mostly impermeable blood-brain barrier.

Medicine

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Hemophilia, Hemophilia A, Hematology, Gene Therapy, clotting factor, Hemostasis, clotting factor VIII

In Crafting New Treatments for Hemophilia, A "Less Is More" Approach

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Hematology researchers have found that blocking the role of a common protein may offer unexpected benefits for patients with the inherited bleeding disorder hemophilia A. The finding offers potential for developing both gene therapy and more effective protein replacement treatments for hemophilia A, the most common form of hemophilia.

Medicine

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Brain Cancer and Leukemia: New Molecular Mechanisms Decoded

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joint research published today in Nature Communications has shown new molecular causes of brain cancer and leukemia.

Medicine

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Sickle Cell, Sickle Cell Anemia, Sickle Cell Anemia Research, Sickle Cell Disease, Gene Editing, Gene Therapy, UCSF Benioff, University of California - Berkeley

Genome Engineering Paves the Way for Sickle Cell Cure

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A team of physicians and laboratory scientists has taken a key step toward a cure for sickle cell disease, using CRISPR-Cas9 gene editing to fix the mutated gene responsible for the disease in stem cells from the blood of affected patients. For the first time, they have corrected the mutation in a proportion of stem cells that is high enough to produce a substantial benefit in sickle cell patients.

Medicine

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Red Blood Cell, Blood, Transfusions, Guidelines, Aaron Tobian, Tobain, Jeffrey Carson, Carson

Expert Panel Issues Updated Guidelines for Red Blood Cell Storage Time and Transfusion Use

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For most stable hospitalized patients, transfusions of red blood cells stored for any time point within their licensed dating period — so-called standard issue — are as safe as transfusions with blood stored 10 days or less, or “fresh,” according to updated clinical guidelines issued by an expert panel convened by a national organization that has long set standards for blood banking and transfusion practices.

Medicine

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Blood Transfusion, blood transfusion threshold, aabb, hemogloblin, Rutgers, JAMA, Robert Wood Johnson

New Guidelines for Life-Saving Blood Transfusions Based on Rutgers Research

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Most patients who need blood transfusions – including those who are critically ill – can be given blood when their hemoglobin drops to a lower level than practiced traditionally, according to AABB, a national association of blood banks that based its recommendation on research led by Rutgers University.







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