American College of Gastroenterology announces 2019 SCOPY Award winners (Service Award for Colorectal Cancer Outreach, Prevention, and Year-Round Excellence) to recognize the achievements of ACG members in their community engagement, education and awareness efforts for colorectal cancer prevention
In a finding that could help lead to new therapies for immune diseases like multiple sclerosis and IBD, scientists report in the Journal of Experimental Medicine identifying a gene and family of proteins critical to the formation of mature and fully functioning T cells in the immune system.
Ciarán P. Kelly, MD, FACG, Professor of Medicine at Harvard Medical School, is available to discuss Celiac Disease: Myths and Mysteries, topic of The American Journal of Gastroenterology Lecture
The recipients of the Mayo Clinic Distinguished Alumni Award have been named:
This this report represents an important opportunity to address better training among physicians around eating disorders.
A study published today in The New England Journal of Medicine found that in patients seen for heartburn unresponsive to treatment with Proton Pump Inhibitors (PPIs), an extensive, systematic workup revealed truly PPI-refractory and reflux-related heartburn in only a minority of cases. In other words, most patients with heartburn unrelieved by PPIs did not have gastroesophageal reflux disease (GERD) causing the symptom. Furthermore, for the selected subgroup identified as having reflux-related, PPI-refractory heartburn, surgery that corrects reflux was significantly superior (67% success rate) to continued medical therapy (28% success rate).
A multi-center randomized clinical trial evaluating a new artificial pancreas system — which automatically monitors and regulates blood glucose levels — has found that the new system was more effective than existing treatments at controlling blood glucose levels in people with type 1 diabetes.The study showed that the system improved participants’ blood glucose control throughout the day and overnight.
Study based at the Icahn School of Medicine at Mount Sinai and other centers finds new system has safety, efficacy benefits for people with type 1 diabetes
Research shows reintroducing soy into a child’s diet first was a promising treatment strategy for children who have both celiac disease and an associated allergic inflammatory disorder called eosinophilic esophagitis.
New research suggests a vaccine that blocks a digestive hormone may slow the spread of pancreatic cancer, potentially increasing survival rates. The study, published ahead of print in the American Journal of Physiology—Gastrointestinal and Liver Physiology, was chosen as an APSselect article for October.
The Center for Medicinal Cannabis Research at University of California San Diego School of Medicine announces $3 million in research grants to explore new applications of cannabis for a number of novel medical applications.
Scientists have made genetic data publicly available for bacteria that might be lurking inside the gut walls of patients chronically affected with severe Crohn’s disease. By studying a surgically removed, damaged bowel from a patient, researchers were able to culture bacteria from a special form of microscopic lesions that they earlier discovered and that can be present within the gut wall of the inflamed bowel in Crohn’s disease. After growing the bacteria in their laboratory, they chose one representative species, and performed a complete genome sequence analysis that could hold clues into how the slow and damaging microlesions form.
An immune cell that helps set the daily rhythms of the digestive system has been identified by researchers at Washington University School of Medicine in St. Louis. The findings open the door to new treatments for digestive ailments targeting such cells.
Findings showcasing a connection between bacteria in the microbiome and colon cancer, which may be used to screen younger populations at risk, were published in the journal Gastroenterology by researchers from the George Washington University.
Das Pankreasadenokarzinom (PDAC) ist ein letales Malignom, das am häufigsten gegen eine Chemotherapie resistent ist. Forscher haben nach Möglichkeiten gesucht, die Anfälligkeit der Tumore für krebsbekämpfende Medikamente zu erhöhen.
L'adénocarcinome du pancréas (PDAC) est une tumeur maligne mortelle qui résiste le plus souvent à la chimiothérapie. Les chercheurs ont cherché des moyens d'accroître la sensibilité des tumeurs aux médicaments anticancéreux.
يُعد اعتلال الغدة الكظرية للقناة البنكرياسية (PDAC) ورمًا خبيثًا قاتلاً وغالبًا ما يقاوم العلاج الكيميائي. يفتش الباحثون عن طرق لزيادة حساسية الأورام للعقاقير المضادة للسرطان.
胰腺癌(PDAC)是一种致命的恶性肿瘤，通常对化疗具有抗药性。研究人员一直在寻找提高肿瘤对抗癌药物的敏感性的方法。Mayo Clinic今日发布的一项自主研究成果在抗癌战役中开辟了一条新战线。
O adenocarcinoma pancreático (ACDP) é um carcinoma letal geralmente resistente à quimioterapia. Os pesquisadores têm buscado formas de aumentar a sensibilidade dos tumores aos medicamentos de combate ao câncer.
Scientists have developed a computer method that may help improve understanding and treatment of Crohn’s disease, which causes inflammation of the digestive tract. The Rutgers-led study, published in the journal Genome Medicine, used artificial intelligence to examine genetic signatures of Crohn’s in 111 people. The method revealed previously undiscovered genes linked to the disease, and accurately predicted whether thousands of other people had the disease.
The three-drug combination of encorafenib, binimetinib and cetuximab significantly improved overall survival (OS) in patients with BRAF-mutated metastatic colorectal cancer (mCRC), according to results of the BEACON CRC Phase III clinical trial led by researchers at The University of Texas MD Anderson Cancer Center.
A new blood test in development has shown ability to screen for numerous types of cancer with a high degree of accuracy, a trial of the test shows.
Good bacteria that live in the guts of mammals program the metabolic rhythms that govern the body’s absorption of dietary fat.
Mount Sinai researchers have identified elemental signatures in baby teeth that are unique to attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, and cases when both neurodevelopment conditions are present, which suggests that the metabolic regulation of nutrients and toxins play a role in these diseases, according to a study published in Translational Psychiatry in September.
In the first clinical trial to evaluate two biologic therapies for moderate to severe ulcerative colitis (UC) head to head, Mount Sinai researchers found vedolizumab to be superior to adalimumab in a variety of measures. In a separate study, the investigators reported that ustekinumab is more effective than placebo as an induction and maintenance therapy for UC. The studies were published today in the The New England Journal of Medicine.
A metabolic imbalance in some cancer patients following treatment with a checkpoint inhibitor drug, nivolumab, is associated with resistance to the immunotherapy agent and shorter survival, report scientists from Dana-Farber Cancer Institute.
El adenocarcinoma pancreático (PDAC, por sus siglas en inglés) es un cáncer mortal y muy a menudo refractario a la quimioterapia. Por ello, los investigadores buscan maneras de mejorar la sensibilidad tumoral a los fármacos contra el cáncer.
A scientific team led by Cedars-Sinai has been awarded $10 million from the U.S. Department of Defense to investigate the risk factors and behaviors that contribute to pancreatic diseases and develop potential treatments and lifestyle recommendations to prevent them.
Within six months of the FDA's move to restrict the label of two immunotherapies, usage of those therapies among oncologists dropped by about 50 percent, according to a new study from researchers in the Abramson Cancer Center at the University of Pennsylvania.
Expert reports estimate that one in three breast cancer cases could be prevented by lifestyle modifications.
Value in Health, the official journal of ISPOR—the professional society for health economics and outcomes research, announced today the publication of research demonstrating that discrete choice experiments are able to predict real-world healthcare choices.
Pathologists are increasingly optimistic about the potential of the human microbiome to help guide diagnosis and monitoring of chronic diseases.
New research led by the University of South Australia shows just how effective bowel cancer screening is in helping to reduce the number of bowel cancer deaths by up to 45 per cent.
Certain human gut microbes with links to health thrive when fed specific types of ingredients in dietary fibers, according to a new study from Washington University School of Medicine in St. Louis. The work — conducted in mice colonized with human gut bacteria and using new technologies for measuring nutrient processing — is a step toward developing more nutritious foods based on a strategy of targeted enrichment of key members of gut microbial communities.
Researchers at Beth Israel Deaconess Medical Center demonstrated for the first time that a strong association between obesity and chronic diarrhea is not driven by diet or physical activity. The findings could have important implications for how physicians might approach and treat symptoms of diarrhea in patients with obesity differently.
Pancreatic adenocarcinoma (PDAC) is a lethal malignancy that most often is resistant to chemotherapy. Researchers have been searching for ways to increase the sensitivity of the tumors to cancer-fighting drugs. A Mayo Clinic-led study published today opens a promising new front in that battle.
In early test tube and mouse studies, investigators at Johns Hopkins Medicine and the Johns Hopkins Kimmel Cancer Center have found that nonmuscle myosin IIC (MYH14), a protein activated in response to mechanical stress, helps promote metastatic behavior in pancreatic cancer cells, and that the compound 4-hydroxyacetophenone (4-HAP), known to stiffen myosin IIC-containing cells, can send it into overdrive, overwhelming the ability of cells to invade nearby tissue.
The American College of Radiology (ACR) has acquired the My CT Colonography center online locator, a patient-friendly online tool to find a computed tomography (CT) colonography screening center near you. The ACR will now work with stakeholders to explore ways to achieve the goal of having all facilities that perform CTC registered on a center locator.
A source of embarrassment to some, or pure comedy to others, flatulence and the gases of the intestines are increasingly seen as playing an important role in our digestive health.
The Icahn School of Medicine at Mount Sinai has been awarded nearly $1.7 million in grant funding from the U.S. Department of Defense to study how bladder cancer affects certain types of white blood cells called “natural killer” cells, or NK cells, which control and limit tumor growth. A clinical and research team of investigators with expertise in bladder cancer and immunotherapy will also design interventions to reverse NK cell dysfunction. According to the U.S. Department of Veterans Affairs, bladder cancer is the fourth most common cancer among veterans. Smoking and exposure to industrial chemicals are the leading causes.
George Washington University researchers published a comprehensive list of the types and ratios of microbes that inhabit the healthy human gut in PLOS ONE, supporting growing research in the field.
If a woodrat is in captivity and is eating an artificial diet, that finely tuned gut microbiome changes. In a paper published in the International Society for Microbial Ecology Journal
A University of Florida microbiologist's latest research found that disease-causing bacteria are competing with their human hosts for a key micronutrient.
RSS
Medicine keyboard_arrow_right
Sciencekeyboard_arrow_right
Life keyboard_arrow_right
Business keyboard_arrow_right
Journal News keyboard_arrow_right
By Location keyboard_arrow_right
Meetings, Grants, and Events keyboard_arrow_right