Researchers at the University of Michigan Health Rogel Cancer Center have identified a drug that, when given along with a bone marrow transplant, drops the risk of leukemia recurring by 20% among the high-risk patients.
Physicians from the Renaissance School of Medicine at Stony Brook University discovered that for patients with severe Covid-19 pneumonia who had higher ferritin in their blood and were treated with a corticosteroid, fewer intubations and deaths resulted. Their findings are reported in JAMA Network Open.
Ian Cheeseman, Ph.D., and his collaborators can now sequence the genomes of individual parasites found in the blood of infected patients -- even when the infection burden is very low, which can occur during asymptomatic infections. Gaining this incredibly detailed view is expected to help develop more effective treatments, vaccines or therapies.
Mount Sinai and UC San Diego researchers have shown for the first time how mutations affecting a cellular process called RNA splicing alter cells to develop myelodysplastic syndrome (MDS) and other hematologic malignancies and solid tumors, according to a study published in Cancer Discovery in October.
More than half of adults between the ages of 50 and 80 have a health condition that puts them at high risk of major health emergencies if they don’t keep their blood pressure under control. But a new poll finds less than half of people in this group regularly check their blood pressure at home or in other places outside the health care system.
New research indicates that an overload of various inflammatory molecules, literally “trapped” inside insoluble microscopic blood clots (micro clots), might be the cause of some of the lingering symptoms experienced by individuals with Long COVID.
Nearly 34 million Americans have blood pressure that’s still too high even though they take medicine to control it. A new study may help them and their doctors decide whether to increase the dose of one of their existing drugs, or add a new one, to bring down their pressure and lower their risk of future health problems.
CAR-T cells are less sensitive than other types of immunotherapy in detecting and killing melanoma cells, a finding that could help improve immunotherapy sensitivity.
The NCCN Virtual Congress: Hematologic Malignancies (#NCCNhem21) will provide the latest evidence and expert consensus on emerging practices and debates in blood cancer treatment, online Thursday, October 14, 2021 – Saturday, October 16, 2021. The NCCN Virtual Nursing Forum will be held October 8, 2021.
Researchers at Washington University School of Medicine in St. Louis have shown that high levels of a specific protein circulating in the blood accurately detect a severe type of peripheral artery disease that narrows the arteries in the legs and can raise the risk of heart attack and stroke.
Blood sugar control has always been important for people with diabetes when it comes to preventing a stroke. But a new study finds for people with diabetes who have a stroke, there may be an ideal target blood sugar range to lower the risk of different types of vascular diseases like a stroke or heart attack later on. The research is published in the September 29, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Mount Sinai researchers have developed a therapy that shows promise against a deadly pediatric leukemia. The small-molecule therapy was highly effective in fighting a type of acute myeloid leukemia in both in vitro and in vivo experiments, according to research published in Science Translational Medicine in September.
Mutations in blood cells likely caused by smoking and aging-related changes may lead to a rare type of blood cancer that affects immune cells, shows a study published today in eLife.
Research presented today at the 2021 AACC Annual Scientific Meeting & Clinical Lab Expo shows that a new test could identify healthcare professionals who are experiencing high levels of work-related stress and anxiety. As COVID-19 cases surge again, this test could play a critical role in helping healthcare professionals on the frontlines of the pandemic to get essential mental health support.
Women ages 70 and older and men ages 20-49 were more likely to have uncontrolled hypertension despite taking blood pressure-lowering medications, according to new research presented today at the American Heart Association’s Hypertension Scientific Sessions 2021.
Princess Margaret Cancer Centre researchers have made new findings which greatly improve detection of the human papillomavirus (HPV) in the bloodstream and could further hone precision treatment of the illness.
Empa researcher Peter Nirmalraj wants to image proteins with unprecedented precision – and thus gain insights into the molecular pathogenesis of Alzheimer's. This should pave the way for an earlier diagnosis of the dementia disorder via a simple blood test. Together with neurologists from the Kantonsspital St.Gallen, a successful pilot study has now been completed.
Sanford Burnham Prebys professor Jamey Marth, Ph.D., has been awarded $13.5 million from the National Heart, Lung, and Blood Institute to continue his team’s work on sepsis, a condition that occurs when infectious and pathogenic organisms enter the bloodstream. This five-year award is a continuation of a multi-institution initiative, now totaling $27 million, that Marth began in 2016 with the goal of identifying the molecular basis of sepsis to achieve more effective treatments.
Researchers from Flinders University and the Robinson Research Institute at the University of Adelaide have identified distinctive biological markers that could improve the routine blood tests pregnant women already undergo and detect risks for pregnancy complications earlier than currently possible.
Omega Bio-tek, a leading nucleic acid purification kit manufacturer, releases an automation-ready, prefilled DNA extraction kit for magnetic processors to purify DNA faster and easier than before. The convenient Mag-Bind® Blood & Tissue DNA HDQ Prefilled 96 Kit comes prefilled with magnetic beads, reagent plates, and tip combs and aims to simplify setup and processing time for magnetic processors such as the Thermo Fisher Scientific KingFisher™ Flex, Qiagen BioSprint®, and the Applied Biosystems MagMax® Express-96.
Patients with dementia who had signs and risk factors of a pulmonary embolism, or a blood clot in the lungs, were much less likely to be tested for pulmonary embolism than patients without dementia who had the same signs and risk factors.
A multifaceted microfluidic in vitro assay is helping to identify the role of hypoxia on red blood cell aging via the biomechanical pathways. It holds promise for investigating hypoxic effects on the metastatic potential and relevant drug resistance of cancer cells.
Every year more than 1.3 million Americans will be living with, or be in remission from, a blood cancer. John Conti, M.D. discusses common symptoms and treatment.
A first-of-its-kind study of young adults with positive COVID-19 tests from more than 4 weeks ago found that those who were still symptomatic (i.e., long-haulers) had impaired blood vessel function in their limbs, but not brains. Asymptotic participants had blood vessel function similar to controls.
MD Anderson to honor the life of trailblazing oncologist Emil J Freireich, M.D., in a virtual tribute event on Sept. 23
A new study at Tel Aviv University found that eosinophils - a type of white blood cells - are recruited to the battle against cancer metastases in the lungs.
Researchers at Children’s Hospital of Philadelphia (CHOP) have demonstrated that an experimental device can improve blood sugar control in patients who developed diabetes after their pancreas was removed to treat their hyperinsulinism, a genetic disease in which the pancreas produces too much insulin. Using a combination of continuous glucose monitoring, two hormone pumps, and an algorithm, the device, known as the bihormonal bionic pancreas (BHBP) and developed by researchers at Boston University, helped HI patients with diabetes maintain stable glucose levels over the study period.
Research Results from Rutgers Cancer Institute of New Jersey Presented at American Urological Association Annual Meeting
A new study led by scientists at Sanford Burnham Prebys has shown that the protein RNF5 plays an unusual role in acute myeloid leukemia (AML). Unlike its expected role, marking aberrant proteins for destruction, RNF5 binds with a second cell protein called RBBP4 to control expression of genes implicated in AML. These findings, published in Nature Communications, have important implications for improving AML patient outcomes.
Kevin David, MD the director of the lymphoma program and a hematologist/oncologist at Rutgers Cancer Institute of New Jersey shares information about leukemias and lymphomas for blood cancer awareness month.
Moffitt Cancer Center has joined Dana-Farber Cancer Institute to provide free screenings to eligible adults who are at a higher risk for having or developing multiple myeloma or other related conditions. This initiative is through the PROMISE Study, a national cancer screening/cohort program to help researchers understand who is at risk based on a number of factors. The goal is to detect multiple myeloma before it becomes symptomatic and to monitor those who are at increased risk in order to study and hopefully prevent the development of the disease.
When most people think about cancer, they tend to think of lumps and bumps, something visible they can see and touch. But with blood cancers, there are no immediate visible signs, just the effects of the cancer in the blood system. John Conti, M.D., explains more.
People who are prescribed the anti-coagulant apixaban cite six major reasons for failing to adhere to their prescriptions, including cost and potential bleeding.
New research has uncovered a precision medicine test using blood proteins to identify a novel patient subgroup of idiopathic multicentric Castleman disease (iMCD), a rare blood disorder, who are more likely to respond to siltuximab, the only FDA approved treatment for the disease.
Lab studies reveal protein HSP27’s role in blood vessel leakage, opening the possibility that therapeutically dialing its activity up or down might stabilize patients with sepsis.
The first large-scale, long-term trial of a new strategy using combinations of very low-doses in one capsule, has demonstrated significantly improved control of high blood pressure – the leading cause of heart attack and stroke.
Placenta accreta spectrum (PAS) disorder occurs when the placenta remains attached to the uterus after childbirth. Now researchers have developed a blood test to identify this condition, enabling early intervention by high-risk pregnancy specialists.
طوّر باحثو مايو كلينك وزملاؤهم في معهد ماساتشوستس للتكنولوجيا (MIT) معجونًا سريع الالتصاق يمكنه إيقاف نزيف الأعضاء بشكل مستقل دون تخثر. التفاصيل منشورة في مجلة الهندسة الطبية الحيوية لنيتشر.
Pesquisadores da Mayo Clinic e colegas do Instituto de Tecnologia de Massachusetts (Massachusetts Institute of Technology, MIT) desenvolveram uma cola de selagem rápida que pode estancar o sangramento de órgãos independentemente da coagulação.
妙佑医疗国际(Mayo Clinic) 的研究人员与麻省理工学院(MIT)的同事们合力研发出了一种快速密封胶，可以在不依赖凝血的情况下快速阻止器官出血。其详细介绍已发表在《自然生物医学工程》(Nature Biomedical Engineering)上。
Los investigadores de Mayo Clinic y sus colegas del Instituto Tecnológico de Massachusetts (MIT, por sus siglas en inglés) elaboraron un pegamento que sella rápido y es capaz de detener el sangrado en los órganos, independientemente de la coagulación.
University of Chicago Medicine clinical research coordinator Aviva Klein, 25, was named to the prestigious 2021 Diana Award Roll of Honour for her work creating the University Blood Initiative (UBI).
When patients exhibit stroke symptoms, doctors must quickly make a life or death determination: Are their symptoms caused by a clot that can be treated with blood thinners or by bleeding in the brain, which may require surgery?
Emergency room patients who were flagged by an artificial intelligence algorithm for possibly having sepsis received antibiotics sooner and had better outcomes, according to a peer-reviewed study conducted by physician-researchers at Case Western Reserve University and MetroHealth.
In a move that will increase access and efficiency of clinical trials for patients with sickle cell disease, UT Southwestern has become a founding member of the new Sickle Cell Disease Clinical Trials Network (SCD CTN) to bring treatments and curative options to people suffering from this potentially life-shortening red blood-cell disorder.
A novel artificial intelligence blood testing technology developed by researchers at the Johns Hopkins Kimmel Cancer Center was found to detect over 90% of lung cancers in samples from nearly 800 individuals with and without cancer.
Expert Q&A: Do breakthrough cases mean we will soon need COVID boosters? The extremely contagious Delta variant continues to spread, prompting mask mandates, proof of vaccination, and other measures. Media invited to ask the experts about these and related topics.
New research published today in JAMA Oncology reports how two separate DNA changes appear to predict aggressive childhood leukemias when they occur in combination. This study illuminates genetic understanding of acute lymphoblastic leukemia in children with the worst outcomes.
A new study from the Perelman School of Medicine at the University of Pennsylvania shows how to overcome resistance to CAR T cell therapy with an experimental small molecule inhibitor.
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