Light stimulates a new twist for synthetic chemistry
Hokkaido UniversityMolecules that are induced by light to rotate bulky groups around central bonds could be developed into photo-activated bioactive systems, molecular switches, and more.
Molecules that are induced by light to rotate bulky groups around central bonds could be developed into photo-activated bioactive systems, molecular switches, and more.
Dartmouth researchers report they have developed the first smartphone application that uses artificial intelligence paired with facial-image processing software to reliably detect the onset of depression before the user even knows something is wrong.
A collaborative team of NIH-funded researchers is developing a way to obtain DNA shed from brain tumors using focused ultrasound. Their first-in-human study could be an important step towards improving the way brain tumors are diagnosed.
In a first-of-its-kind study, researchers at the Georgia Institute of Technology discovered that sea cucumbers — sediment-eating organisms that function like autonomous vacuum cleaners of the ocean floor — play an enormous role in protecting coral from disease. The problem is, they've been overharvested for more than 100 years, and they're now rare.
Scientists at the U.S. Department of Energy’s Princeton Plasma Physics Laboratory are working on ways to improve thrusters for satellites operating in very low orbit around the Earth. The researchers believe they can make satellites that weigh less, last longer and cost less by creating thrusters that use the air around them instead of having to carry its own supply of fuel. PPPL’s diagnostics will be used to evaluate this innovative thruster concept and characterize key physical processes involved in its operation.
A team of researchers from Wayne State University and the Barbara Ann Karmanos Cancer Institute has received a five-year, $9.6 million grant from the National Cancer Institute of the National Institutes of Health for the study “Genetic Variation in Cancer Risk and Outcomes in African Americans.” This is a Program Project Grant that includes three large studies. The team will work to improve the identification and clinical management of hereditary and multiple primary cancers in African Americans, a population that is currently underrepresented in genetic research.
Scientists report a major step toward a simple blood test for Alzheimer’s disease. Researchers at Washington University School of Medicine in St. Louis and Lund University in Sweden showed that a blood test is as good at identifying people in early stages of the disease as cerebrospinal fluid tests approved by the Food and Drug Administration (FDA) for Alzheimer’s diagnosis. The findings indicate that a blood test soon may replace more expensive and invasive brain scans and spinal taps for detecting signs of Alzheimer’s in the brain.
The effects of a phenomenon called tree masting on ecosystems and food webs can be better understood thanks to new theoretical models validated by real world observations.
Obesity care under a health care provider’s supervision, whether through nutrition counseling, medication, meal replacement or bariatric surgery, can help people with high BMI, but many don’t receive it.
Could the TB vaccine be a new immunotherapy for liver cancer? A UC Davis Health study found that the century-old vaccine reduced tumors and extended survival for mice with liver cancer.
Regenerative therapy to treat heart failure is more effective when the mitochondria of the regenerative cells are activated prior to treatment.
The qualities of flowing blood, or hemodynamics, hold important insights into vascular diseases, but technological limitations have largely kept measurements of these properties out of reach in the clinic. Now, there may be a potential solution on the horizon.
In a study published in the journal Environmental Science & Technology, WashU researchers discovered that a common mineral called goethite — an iron-rich mineral that is abundant in soils that cover the Earth — tends to incorporate trace metals into its structure over time, binding the metals in such a way that it locks them out of circulation.
Tufts University School of Medicine researchers develop imaging technology that records neuronal activity throughout the brain during the first weeks of recovery from traumatic brain injury
Researchers from the Icahn School of Medicine at Mount Sinai, in collaboration with the Clinical Proteomic Tumor Analysis Consortium of the National Institutes of Health, The University of Texas MD Anderson Cancer Center, Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, and others, have unveiled a detailed understanding of immune responses in cancer, marking a significant development in the field. The findings were published in the February 14 online issue of Cell. Utilizing data from more than 1,000 tumors across 10 different cancers, the study is the first to integrate DNA, RNA, and proteomics (the study of proteins), revealing the complex interplay of immune cells in tumors. The data came from the Clinical Proteomic Tumor Analysis Consortium (CPTAC), a program under the National Cancer Institute.
Findings from St. Jude Children’s Research Hospital showed a novel dual targeting approach, where a single molecule can recognize two potential cancer-related proteins, is more effective than the single targeting approach, preventing immune escape.
A team of researchers from Wayne State University was awarded a $1.4 million, three-year grant from the U.S. Department of Defense for the study, “Cytochrome c acetylation drives prostate cancer aggressiveness and Warburg effect.”
Researchers in a Johns Hopkins Children’s Center-led study say they have made progress in developing a blood test to identify disease-associated changes in the brain specifically linked to postpartum depression and other psychiatric and neurological disorders.
Researchers at the Icahn School of Medicine at Mount Sinai have identified a new approach to controlling bacterial infections. The findings were described in the February 6 online issue of Nature Structural & Molecular Biology.
Employing massive data sets collected through NASA’s James Webb Space Telescope, a research team led by a Rutgers University–New Brunswick astronomer is unearthing clues to conditions existing in the early universe. The team has catalogued the ages of stars in the Wolf–Lundmark–Melotte (WLM) galaxy, constructing the most detailed picture of it yet, according to the researchers.
Scientists at La Jolla Institute for Immunology (LJI) have uncovered important clues to how human T cells combat the bacterium that causes tuberculosis.
Mahsa Dabagh is building a virtual model of a real human tumor, using data that characterizes the tissue on a molecular level.
Montefiore Health System and Albert Einstein College of Medicine have been awarded a $1.5 million National Institutes of Health grant to provide advanced research training to post-graduate trainees from groups that are underrepresented in medicine and have research interests in heart, lung, blood, and sleep disorders. Over five years, nine researchers will receive intense research training and robust mentorship from almost 30 established, senior investigators across Montefiore and Einstein.
Artificially intelligent software has been developed to enhance medical treatments that use jets of electrified gas known as plasma. Developed by researchers at Princeton Plasma Physics Laboratory and the George Washington University, the computer code predicts the chemicals emitted by cold atmospheric plasma devices, which can be used to treat cancer and sterilize surfaces.
A groundbreaking study from the University of Pennsylvania School of Nursing (Penn Nursing), recently published in Innovation in Aging, has shown promising results in improving the quality of life (QOL) and sleep quality in individuals living with memory problems.
Black adults across the United States suffer from sleep problems following exposure to news about unarmed Black individuals killed by police during police encounters, according to new findings published today in JAMA Internal Medicine from researchers at the University of Pennsylvania Perelman School of Medicine.
UC San Diego engineers have developed an ultra-sensitive sensor made with graphene that can detect extraordinarily low concentrations of lead ions in water.
The Windreich Department of Artificial Intelligence (AI) and Human Health at the Icahn School of Medicine at Mount Sinai announced a transformative $1.95 million gift from Schmidt Sciences to create The Eric and Wendy Schmidt AI in Human Health Fellowship Program.
A research study led by a multidisciplinary team of scientists at Roswell Park Comprehensive Cancer Center details evidence on the therapeutic efficacy of a compound that targets a key genetic feature of pancreatic cancer.
As new cancer treatments become available, some of the most important ongoing research must look at ways to optimize those new approaches so that more patients can benefit from groundbreaking therapies.
Theoretical predictions have been confirmed with the discovery of an outflow of molecular gas from a quasar when the Universe was less than a billion years old.
A new study of data from veterans who had tried many depression treatments but still had severe symptoms suggests a series of intravenous doses of ketamine gave many at least partial relief. For a minority, it led to full remission.
A combination of two cancer drugs could be effective against malignant peripheral nerve sheath tumors (MPNSTs), according to a laboratory study led by researchers at the Johns Hopkins Kimmel Cancer Center.
An international team that includes Rutgers University–New Brunswick scientists has developed a new method to make and manipulate a widely studied class of high-temperature superconductors.
Modeling shows that stratospheric aerosol injection has the potential to reduce ice sheet loss due to climate change.
A new technology to increase visibility of cancer cells to the immune system using CRISPR has been developed, and could lead to a new way to treat cancer.
Subcutaneous injection of the immunotherapy nivolumab (brand name Opdivo) is noninferior to intravenous delivery and dramatically reduces treatment time in patients with renal cell carcinoma, as seen in the results of a large phase 3 clinical trial reported today at the 2024 American Society of Clinical Oncology (ASCO) Genitourinary Cancers Symposium in San Francisco, California.
In an advance for cultivated meat technology, researchers have developed bovine muscle stem cells that produce their own growth factors, eliminating the need to add the expensive ingredient in the growth media.
Srikanth Singamaneni and Barani Raman, both professors in the McKelvey School of Engineering at Washington University in St. Louis, led a team that harnessed the power of specially made nanostructures to enhance the neural response in a locust's brain to specific odors and to improve their identification of those odors.
Working with mammalian retinal cells, neuroscientists at Johns Hopkins Medicine have shown that, unlike most light-sensing cells (photoreceptors) in the retina, one special type uses two different pathways at the same time to transmit electrical “vision” signals to the brain.
Emerging research from the Department of Energy’s Princeton Plasma Physics Laboratory (PPPL) suggests it may be easier to use fusion as a power source if liquid lithium is applied to the internal walls of the device housing the plasma.
A water-soluble, luminescent europium complex enables evaluation of malignancy grade in model glioma tumor cells.
In a few years, popcorn could become a standard element in science classrooms across Illinois and the nation. With funding from a new USDA grant, a University of Illinois Urbana-Champaign crop scientist and collaborating educators are developing a popcorn-based curriculum to reinforce concepts around agricultural science, artificial intelligence, biotechnology, computer science, genomics, research methods, and more for 4-H and high school students.
Temperature-controlled, reversible shifting of molecular gear motion in a solid crystal opens new possibilities for material design.
A team at NYU Tandon School of Engineering will kick off the second phase of an ambitious research project that aims to transform navigation and accessibility for many of the 285 million people with blindness and low vision (pBLV) worldwide.
A Rutgers researcher, through his spinoff company, has led a team to design and test a device that quickly counts a person’s white blood cells with a single drop of blood, similar to the way glucometers rapidly scan for blood sugar levels. T
Researchers at the National Eye Institute (NEI) have improved a crucial step in the production of retinal pigment epithelium (RPE), a tissue they grow in the lab from patient blood cells and are testing in a clinical trial as treatment for age-related macular degeneration (AMD).
"These patients may be candidates in whom immunotherapy has the potential to show clinical benefit."
A civil engineer at the University of Pittsburgh is applying his expertise in bridges and infrastructure to develop new materials that better treat spinal injury, repair, and recovery.
A new study in Cell Metabolism by a team from the Monell Chemical Senses Center unravels the internal neural wiring of separate fat and sugar craving pathways in a mouse model. However, combining these pathways overly triggers a desire to eat more than usual.