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Medicine

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Cystic Fibrosis, Cystic Fibrosis Foundation, Cystic Fibrosis Lung Disease, VX-152 , Vertex Pharmaceuticals , F508del, F508del/Min, F508del mutation, three-drug modulator studies , CFTR gene, FDA, G551D, Kalydeco, Research, Precision Medicine

New Data Show Three Triple-Combination Regimens Are “Highly Effective” for Up to 90 Percent of Cystic Fibrosis Patients

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A UAB physician will co-chair a steering committee of global cystic fibrosis experts and clinical trial investigators to support the design, conduct and execution of the triple combination pivotal study program.

Science

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Whales, Marine Biology, Zoology, Genetics, Medicine & Health, Eating Disorder, Obesity

One Amino Acid, a Whale of a Difference

A single amino-acid variation in a key receptor in whales may help explain why some species of cetaceans evolved sleek, muscular bodies to hunt fish and seals, while others grow to massive sizes by filter-feeding on large volumes of plankton, an international research team has found.

Science

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iwgsc, wheat genome sequencing, wheat genome, Board Announcement

Wheat Sequencing Consortium Announces New Appointment to Board of Directors

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Sébastien Praud, Biogemma Genetics and Genomics in Cereals team leader, has been appointed to the Board of the International Wheat Genome Sequencing Consortium.

Medicine

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Lupus

Large Multi-Ethnic Study Identifies Many New Genetic Markers for Lupus

Scientists from an international consortium have identified a large number of new genetic markers that predispose individuals to lupus.

Science

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DNA, eDNA, David Lodge, Kristy Deiner, Invasive Species, Endanged Species, Genetics, fish

DNA Tracking Tool Tips the Scales for Distinguishing Invasive Fish

Rather than conduct an aquatic roll call with nets to know which fish reside in a particular body of water, scientists can now use DNA fragments suspended in water to catalog invasive or native species.

Medicine

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Sanford Burnham Prebys Medical Discovery Institute, Bioinformatics, Cancer Genes, Adam Godzik

Comparing Algorithms That Search for Cancer Mutations

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Scientists team up to evaluate the tools used to probe the cancer genome

Medicine

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Newly Discovered Gene Variants Link Innate Immunity and Alzheimer’s Disease

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Three new gene variants, found in a genome wide association study of Alzheimer’s disease (AD), point to the brain’s immune cells in the onset of the disorder. These genes encode three proteins that are found in microglia, cells that are part of the brain’s injury response system.

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High-Energy Shock Waves, Plasma Behavior, Algae Production, and More in the DOE Science News Source

Click here to go directly to the DOE Science News Source

Medicine

Science

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Jeffrey Mumm, eye, Immune System, Zebrafish

Immune System Found to Control Eye Tissue Renewal in Zebrafish

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Researchers at Johns Hopkins Medicine report evidence that zebrafishes’ natural ability to regenerate their eyes’ retinal tissue can be accelerated by controlling the fishes’ immune systems. Because evolution likely conserved this mechanism of regenerative potential in other animals, the new findings may one day advance efforts to combat degenerative eye disease damage in humans.

Medicine

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triple-negative breast cancer, Resistance, Anti-viral

Cancer Cells Force Normal Cells to Mimic Viruses to Help Tumors Spread, Resist Treatment

In a study that could explain why some breast cancers are more aggressive than others, researchers say they now understand how cancer cells force normal cells to act like viruses – allowing tumors to grow, resist treatment, and spread. The virus mimic is detected in the blood of cancer patients, particularly in cases of an aggressive type known as triple-negative breast cancer. Researchers from the Perelman School of Medicine at the University of Pennsylvania say cracking the code of how this process works opens up the possibility of targeting this mechanism for treatment.







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