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Alzheimer's and Dementia

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Medicine

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Alzheimer's Disease, Dementia, Genetic Predisposition, Apoe 4, Neuroscience

Detecting Alzheimer’s Disease Earlier Using … Greebles?

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Unique graphic characters called Greebles may prove to be valuable tools in detecting signs of Alzheimer’s disease decades before symptoms become apparent.

Medicine

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Alzheimer's, Diabetes, , Neurodegenerative, Protein, Misfolded Protein Diseases, Brain, Glucose, Neural Tube Defect, Embryo, Pregnancy, Women

Researchers Identify Link Between Birth Defect and Neurodegenerative Diseases

A new study has found a link between neurological birth defects in infants commonly found in pregnant women with diabetes and several neurodegenerative diseases, including Alzheimer’s, Parkinson’s and Huntington’s diseases. This is the first time this link has been identified; it may indicate a new way to understand, and perhaps treat, both neural tube defects and these neurodegenerative diseases.

Medicine

Science

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Alzheimer, AI, Crowdsourcing, Documentary, Alzheimer's, Dementia, Competition, Human Computation

TV Crowd to Help Crush Alzheimer's

EyesOnALZ (http://eyesonalz.com) – a project to crowdsource Alzheimer’s research is launching an online competition to #CrushALZ on April 6th, in partnership with The Crowd & The Cloud – a public television documentary series about citizen science.

Medicine

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ADT, Prostate Cancer, Dementia, Alzheimber's Disease

Link between Common Prostate Cancer Treatment, Dementia Detailed in New Study

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A new analysis of patients who have undergone treatment for prostate cancer shows a connection between androgen deprivation therapy (ADT) – a testosterone-lowering therapy and a common treatment for the disease – and dementia, according to researchers from the Perelman School of Medicine at the University of Pennsylvania.

Medicine

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Seth Margolis, Alzheimer’s, ephexin5 , Brain, Amyloid

Protein That Regulates Brain Cell Connections Could Be New Target for Treating Alzheimer's Disease

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In experiments with a protein called Ephexin5 that appears to be elevated in the brain cells of Alzheimer's disease patients and mouse models of the disease, Johns Hopkins researchers say removing it prevents animals from developing Alzheimer's characteristic memory losses. In a report on the studies, published online March 27 in The Journal of Clinical Investigation, the researchers say the findings could eventually advance development of drugs that target Ephexin5 to prevent or treat symptoms of the disorder.

Medicine

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Diabetes, insulin spray, Insulin, Cognitive Decline, Mild Cognitive Impairment, Memory, Aging, Alzheimer's Disease

Sniffing Out a New Strategy Against Alzheimer’s Disease

Neurologists at the Rush Alzheimer’s Disease Center are conducting an 18-month clinical trial testing a type of insulin delivered in a nasal spray – which is used to treat diabetes in some patients – in the Study of Nasal Insulin to Fight Forgetfulness (SNIFF).

Medicine

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Alzheimber's Disease, Dementia

Gene Discovered Associated with Tau Pathology

Investigators at Rush University Medical Center and the Brigham and Women’s Hospital in Boston reported the discovery of a new gene that is associated with susceptibility to a common form of brain pathology called Tau that accumulates in several different conditions, including Alzheimer’s disease, certain forms of dementia and Parkinsonian syndromes as well as chronic traumatic encephalopathy that occurs with repeated head injuries.

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California Researchers Awarded $100,000 Potamkin Prize for Dementia Research

The American Academy of Neurology is awarding two California researchers the 2017 Potamkin Prize for Research in Pick’s, Alzheimer’s and Related Diseases for their work in dementia research. Claudia Kawas, MD, of the University of California, Irvine, and Kristine Yaffe, MD, of the University of California, San Francisco, both members of the American Academy of Neurology, will be honored at the American Academy of Neurology’s 69th Annual Meeting in Boston.

Science

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Alzheimber's Disease, Neurochemistry

Researchers Focus on Cell Membranes to Develop Alzheimer's Treatments

Thin parts of the cell membranes of neurons turn out to be particularly vulnerable to a protein that collects in the brain of people with Alzheimer's disease, according to a University of Michigan researcher.

Medicine

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Pavlovian response, NEURON ACTIVITY, Alzheimer's Disease, Parkinson's Disease, Tourette Syndrome, Learning

Study Identifies Brain Cells Involved in Pavlovian Response

UCLA scientists have traced the Pavlovian response to a small cluster of brain cells -- the same neurons that go awry during Huntington’s disease, Parkinson’s disease and Tourette syndrome. The research could one day help scientists find new approaches to diagnosing and treating these neurological disorders.







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