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Medicine

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DNA, Dna Repair, Cellular Aging, Mysteries of Aging, Dna Damage, Molecule NAD, Repairing DNA, Cell Ageing, Harvard Medical School Scientists, NAD, NMN, Sirt1, PARP1, DBC1, Genetics, protein binding, David Sinclair

Harvard Medical School Scientists Pinpoint Critical Step in DNA Repair, Cellular Aging

The body’s ability to repair DNA damage declines with age, which causes gradual cell demise, overall bodily degeneration and greater susceptibility to cancer.

Medicine

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Limiting Protein Reduces Post-Heart Attack Injury in Mice

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According to the Centers for Disease Control and Prevention, approximately 735,000 Americans experience a heart attack each year. Opening a blocked coronary artery to restore blood flow to the heart prevents sudden cardiac death. However, doing so also triggers cardiac damage through oxidative stress and inflammation, which eventually can lead to heart failure. In a new study, researchers at the University of Missouri School of Medicine have identified a protein that can be targeted to decrease post-heart attack injury and prevent heart failure in a mouse model.

Medicine

Life

Social and Behavioral Sciences

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Mental Illness, Mental Health, Psycholgoy, Depression, DSM-5, Mental Disorder, Major depressive disorder (MDD)

Research Consortium Develops Evidence-Based Diagnostic Model for Mental Illness

Researchers have developed a new, evidence-based alternative to the mental health field’s long-established diagnostic tools for the classification, treatment, and research of mental disorders. The Hierarchical Taxonomy of Psychopathology (HiTOP) addresses what the authors say are limitations to the reliability and validity of traditional models.

Science

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Biology, Regenerative Medicine, regenerative biology

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 30-Mar-2017 6:00 AM EDT

Science

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NASA, Hubble Space Telescope, Wide Field Camera 3, active galaxies, Quasars, 3C 186, Gravitational Waves, Black Holes

Gravitational Wave Kicks Monster Black Hole Out of Galactic Core

An international team of astronomers using NASA's Hubble Space Telescope have uncovered a supermassive black hole that has been propelled out of the center of the distant galaxy 3C 186. The black hole was most likely ejected by the power of gravitational waves.

Medicine

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EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 24-Mar-2017 4:00 PM EDT

Life

Business

Social and Behavioral Sciences

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Bullying, bullying solutions, workplace bullying, organizational communication, work culture, Harrassment

Does Advice for Managing Workplace Bullying Really Work?

In a new study featured in the National Communication Association’s Journal of Applied Communication Research, authors Stacy Tye-Williams and Kathleen J. Krone identify and re-imagine the paradox of workplace bullying advice. They interviewed 48 individuals from a variety of occupations and found that targets of workplace bullying frequently offered advice they had received to other targets, despite believing that the advice either made no difference or had made their own situations worse.

Medicine

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Suburban Hospital, Wade Chien, Gene Therapy, Hearing Loss, DEAF, Deafness, Dizziness

Novel Gene Therapy Experiment Offers Hope for People with Certain Hearing Loss and Dizziness Disorder

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In a first-of-its-kind study published in the March 1, 2017 edition of Molecular Therapy, researchers from the National Institute on Deafness and Other Communication Disorders (NIDCD) and Johns Hopkins University School of Medicine showed that gene therapy was able to restore balance and hearing in genetically modified mice that mimic Usher Syndrome, a genetic condition in humans characterized by partial or total hearing loss, dizziness, and vision loss that worsens over time. The hearing loss and dizziness is caused by abnormalities of the inner ear.

Medicine

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Cancer, Prostate Cancer, TMPRSS2:ERG, Peptides, Peptidomimetics, Gene Fusion

A New Approach to Target an ‘Undruggable’ Prostate Cancer Driver

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When small-molecule inhibitors proved elusive, researchers developed a novel strategy: Using large molecule peptides to target a common prostate cancer driver. It may provide a path for developing new therapies against a challenging target.

Medicine

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Duke University Medical Center, Duke University School of Medicine, Duke University, Duke Health, Gender Identity, Transgender, transgender health, transgender medicine, College Student Drinking, College Student Health, College Freshmen, Binge Drinking, Alcohol Abuse, alcohol aggressive behavior, alcohol and violence, Alcohol, Blackouts, Scott Swartzwelder

Transgender College Freshmen Drink More, Experience More Blackouts

A survey of more than 422,000 college freshmen found that students who identified as transgender were more likely than their cisgender peers to experience negative consequences from drinking, including memory blackouts, academic problems and conflicts such as arguments or physical fights.







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