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NewswiseBelow are some of the latest research and features on this growing population of older adults in the Seniors channel on Newswise.
Below are some of the latest research and features on this growing population of older adults in the Seniors channel on Newswise.
A new clinical trial, led by clinicians and researchers at the UNC School of Medicine, show that the combination of the drug vorinostat and immunotherapy may modestly shrink the latent HIV reservoir, but more work needs to be done in the field to create a cure.
Patients with soft-tissue sarcoma treated with neoadjuvant, or pre-surgical, immunotherapy had very little residual tumor at the time of surgery and promising long-term survival, according to Phase II trial results published today in Nature Cancer by researchers at The University of Texas MD Anderson Cancer Center
Findings from St. Jude Children’s Research Hospital showed a novel dual targeting approach, where a single molecule can recognize two potential cancer-related proteins, is more effective than the single targeting approach, preventing immune escape.
A Encefalite é uma doença que envolve a inflamação ou inchaço do cérebro. Isso pode acontecer devido a infecções ou problemas no sistema imunológico, e o tratamento precoce é importante.
التهاب الدماغ هو مرض ينطوي على التهاب أو تورم الدماغ. ويمكن أن يحدث بسبب التهابات أو مشكلات تصيب الجهاز المناعي، والعلاج المبكر لتلك الحالة مهم. يقول ساروش إيراني، بكالوريوس الطب والجراحة.، طبيب الأعصاب، وباحث في مايو كلينك في جاكسونفيل، فلوريدا أنه لهذا السبب من الضروري رفع مستوى الوعي.
La Encefalitis es una enfermedad que implica inflamación o hinchazón del cerebro. Esto puede suceder debido a infecciones o problemas con el sistema inmunológico, y el tratamiento temprano es importante.
NJ-based Atlantic Health System is the first in the U.S. to enroll a patient in a study to examine the effectiveness of using Chimeric Antigen Receptor (CAR- T) cells in the treatment of the autoimmune disease lupus.
Recognizing the impact of his research and outstanding leadership in the field of immunology, Gary Koretzky, M.D., Ph.D., DFAAI (AAI ’92), will receive the American Association of Immunologists (AAI) Lifetime Achievement Award, the association’s highest honor, at the AAI annual conference IMMUNOLOGY2024TM, May 3-7 in Chicago.
Scientists at La Jolla Institute for Immunology (LJI) have uncovered important clues to how human T cells combat the bacterium that causes tuberculosis.
Through an analysis of tumor samples collected over time from patients with advanced melanoma, a Ludwig Cancer Research study has identified a set of preexisting conditions in tumors that predict whether such patients are likely to respond to a personalized immunotherapy known as adoptive T cell therapy (ACT) using tumor-infiltrating lymphocytes (TIL).
For years, there has been a long-held belief that acute viral infections like Zika or COVID-19 are directly responsible for neurological damage, but researchers from McMaster University have now discovered that it’s the immune system’s response that is behind it.
The intricate relationship that exists between humans and the gut microbiome has become a hot research topic, and scientists are constantly uncovering new reasons why a healthy diet can lead to a healthier life.
For 21 years, nurses have consistently been the most trusted profession, according to the yearly Gallup poll. (The new poll will be issued by the end of January). Dr Rushton, who specializes in burnout, will speak on trust, moral injury, and how nurses cope in this day and age.
Non-small cell lung cancer (NSCLC), with an epidermal growth factor receptor (EGFR) mutation, tends not to respond well to immunotherapy treatments, including durvalumab. However, Yale Cancer Center (YCC) researchers recently reported in the Journal of Thoracic Oncology that the targeted therapy osimertinib, when administered after chemotherapy and radiation, is associated with significantly improved progression-free survival (living without the cancer worsening).
Treatment with a molecule known as A485 can quickly and temporarily increase levels of white blood cells, a critical part of the body’s immune system, an effect that is difficult to deliver with currently available pharmaceuticals, a new Yale study finds.
In a rare but serious complication of cancer, the immune system can start attacking the brain, causing rapid memory loss. What triggers this was largely unknown. Now, researchers at University of Utah Health have found that some tumors can release a virus-like protein, kickstarting an out-of-control autoimmune reaction.
The latest research and expertise on the flue can be found in the Influenza channel on Newswise.
Sergio E. Baranzini, PhD, a geneticist, neuroimmunologist, and data scientist at the University of California, San Francisco, is the winner of this year’s Barancik Prize for Innovation in MS Research.
Tomato juice can kill Salmonella Typhi and other bacteria that can harm people's digestive and urinary tract health, according to research published this week in Microbiology Spectrum, a journal of the American Society for Microbiology.
A new technology to increase visibility of cancer cells to the immune system using CRISPR has been developed, and could lead to a new way to treat cancer.
It is with great pleasure that we announce the appointment of Lydia Lynch as a full member of the Princeton Branch of the Ludwig Institute for Cancer Research.
Storb was a Professor in the Department of Molecular Genetics and Cell Biology for more than 29 years.
One major hurdle in the development of safe and effective immunotherapies has been the risk of depleting healthy T cells during CAR-T treatment that seeks out and kills cancerous T-cells. In a new study published in Nature Communications, Yale Cancer Center researchers have developed a novel CAR-T cell therapy designed to efficiently kill cancerous T cells while leaving most healthy cells intact.
Over 700 million people were infected and almost seven million died, making SARS-CoV-2 the most devastating pandemic of the 21st century.
Researchers from IRB Barcelona describe a mechanism by which senescent cells generated by chemotherapy survive inside tumours.
RUDN University doctors have studied how anti-inflammatory immune cells can help mitigate an excessive immune response. The authors discovered both positive and negative aspects of the new approach, but overall they proved its promise.
Molecular defense system protects bacteria from viruses and at the same time makes them susceptible to antibiotics.
Researchers with McMaster University have created the instruction manual that will help scientists across the globe find hard to detect B cells.
Six physician-scientists from the University of Pennsylvania Perelman School of Medicine and Children’s Hospital of Philadelphia have been elected to the American Society of Clinical Investigation, joining one of the nation’s oldest and most respected medical honor societies composed of more than 3,000 physician-scientists representing all medical specialties.
Most people infected with the SARS-CoV-2 virus recover after the acute illness.
“We found sort of a special ‘flavor’ of CD4+ T cells critical for clearing this chronic virus replication,”
"These patients may be candidates in whom immunotherapy has the potential to show clinical benefit."
A Ludwig Cancer Research study has generated a granular portrait of how the cellular and molecular components of the blood vessels that feed brain metastases of melanoma and lung and breast cancers differ from those of healthy brain tissue, illuminating how they help shape the internal environment of tumors to support cancer growth and immune evasion.
Kelly Kersten, Ph.D., who joined Sanford Burnham Prebys this month as an assistant professor in the Cancer Metabolism and Microenvironment program, studies the interactions between immune cells and their microenvironment to better understand how they contribute to anti-tumor immune responses.
Axi-cel CAR T targets the CD19 molecule on large B-cell lymphoma cells. The ZUMA-7 trial demonstrated that axi-cel reduced the risk of disease progression, the need for new therapy, or death by 60% compared to standard therapy. Despite these positive outcomes in event-free survival and overall survival, some patients did not respond well to therapy or relapsed quickly after treatment. Researchers wanted to assess if there were specific tumor characteristics associated with improved outcomes that could better inform treatment selection. Their findings were published today in Nature Medicine.
The award recognizes Dr. Chacon’s role as co-inventor of a licensed patent involving cancer immunotherapy.
By taking advantage of mechanisms that allow cancer cells to evade immune attack, UT Southwestern Medical Center researchers have developed a new strategy in animal models that has potential for treating ulcerative colitis.
Recent SARS-CoV-2 variants such as BA.4 and BA.5 developed abilities missing from the first Omicron variants that allowed them to overcome humans’ innate immunity, according to research from UCL.
Tuberculosis (TB) is the leading infectious killer worldwide, with 10.6 million cases and 1.6 million deaths in 2021 alone. One in five incident TB cases were attributable to malnutrition, more than double the number attributed to HIV/AIDS.
Two studies led by a researcher at UT Southwestern Medical Center show the effects of different SARS-CoV-2 variants on lung tissue, revealing what may cause some COVID-19 infections to be more severe than others.
Researchers from Osaka University find characteristic changes in CD4+ T cell categories and gene programs associated with autoimmune disease.
A new paper in Molecular Biology and Evolution, published by Oxford University Press, finds that HIV populations in people with higher viral loads also have higher rates of viral recombination.
Cedars-Sinai Cancer investigators have analyzed the cells within triple-negative breast cancer tumors before and after radiation therapy with immunotherapy, identifying three patient groups with different responses to the treatment.
The body’s immune response to Epstein-Barr virus (EBV) may play a role in causing damage in people with multiple sclerosis, according to a new study led by UTHealth Houston.
Scientists have solved a cellular murder mystery nearly 25 years after the case went cold. Following a trail of evidence from fruit flies to mice to humans revealed that cannibalistic cells likely cause a rare human immunodeficiency.
Researchers at the University of Michigan Health Rogel Cancer Center have identified a mechanism that causes severe gastrointestinal problems with immune-based cancer treatment, also finding a way to deliver immunotherapy’s cancer-killing impact without the unwelcome side effect.