A study led by Johns Hopkins Bloomberg School of Public Health researchers found that injecting a vaccine-like compound into mice was effective in protecting them from malaria. The findings suggest a potential new path toward the elusive goal of malaria immunization.
Researchers reveal how a lung-damaging bacterium turns the body's antibody response in its favor.
As the Food and Drug Administration mulls over whether to rein in the use of common antibacterial compounds that are causing growing concern among environmental health experts, scientists are reporting today that many pregnant women and their fetuses are being exposed to these substances. They will present their work at the 248th National Meeting & Exposition of the American Chemical Society, the world’s largest scientific society.
Wrapping wound dressings around fingers and toes can be tricky, but for burn victims, guarding them against infection is critical. Today, scientists are reporting the development of novel, ultrathin coatings called nanosheets that can cling to the body’s most difficult-to-protect contours and keep bacteria at bay. They’re speaking about their materials, which they’ve tested on mice, at the 248th National Meeting & Exposition of the American Chemical Society, the world’s largest scientific society.
The misfolded and infectious prion protein that is a marker for variant Creutzfeldt-Jakob disease – linked to the consumption of infected cattle meat – has been detected in the urine of patients with the disease by researchers at The University of Texas Health Science Center at Houston (UTHealth) Medical School.
Two birds with one stone: A novel and broad Ebola vaccine in humans or with specially engineered cows could help researchers develop large quantities of Anti-Ebola serum and protect humans against filoviruses.
St. Jude Children’s Research Hospital scientists have discovered an enzyme that regulates production of the toxins that contribute to potentially life-threatening Staphylococcus aureus infections. The study recently appeared in the scientific journal the Proceedings of the National Academy of Sciences (PNAS).
Lice are highly contagious and tough to treat and remove. Here are some facts, tips and personal experiences with the tiny, parasitic insects.
Scientists try to stay a step ahead of HIV in order to combat drug resistance and to develop better treatments.
Among mechanically ventilated intensive care unit (ICU) patients, receipt of high-protein nutrition via a feeding tube enriched with immune-modulating nutrients vs standard high-protein nutrition did not result in a significant difference in the incidence of new complications.
Laboratories at The Scripps Research Institute are investigating antibodies to fight Ebola virus, including the three antibodies recently used to treat two American health care workers infected with the Ebola virus.
Effective new drugs and screening would make hepatitis C a rare disease by 2036, according to a computer simulation conducted by The University of Texas MD Anderson Cancer Center and the University of Pittsburgh Graduate School of Public Health.
New technique sustains virus in liver cells, allowing study of immune response and drug treatments.
Crafty parasites undergo dramatic shape changes that enable them to adapt to different living conditions and thrive. Researchers show that these transformations might not be as difficult as they appear.
Harnessing a natural process in the body that pumps lethal doses of copper to fungi and bacteria shows promise as a new way to kill infectious microbes, a team of scientists at Duke University report.
A recently published study looks at the discovery of porcine enterovirus G, which is an important find in the United States.
Up to 5 percent of all prenatal ultrasounds uncover antenatal hydronephrosis, or enlarged kidneys, the most commonly detected prenatal abnormality in the U.S. Many children with this abnormality are treated continually with preventive antibiotics for the first few years of life with the hopes of preventing the condition’s associated urinary tract infections. Until recently, however, little evidence existed as to the benefits of this treatment, which involves considerable cost and inconvenience for families. But a new study found that, in most cases, continuous antibiotics for these children are unnecessary, findings that are especially of interest amidst increasing concern regarding antibiotic overuse.
A rare procedure occasionally performed during Jewish circumcisions that involves direct oral suction is a likely source of herpes simplex virus type 1 (HSV-1) transmissions documented in infants between 1988 and 2012, a literature review conducted by Penn Medicine researchers and published online in the Journal of the Pediatric Infectious Diseases Society found.
Scientists at Duke Medicine have found an immunologic mechanism that makes broadly neutralizing antibodies in people who are HIV-1 infected.
Researchers have uncovered a way the malaria parasite becomes resistant to an investigational drug. The discovery, at Washington University School of Medicine in St. Louis, also is relevant for other infectious diseases including bacterial infections and tuberculosis.
Kansas State University leading researcher in chikungunya virus says many more people are at risk of getting infected now that mosquitoes in the U.S. are carrying the virus.
The St. Jude Children’s Research Hospital VOICES project is the focus of the “A Piece of My Mind” column in the July 22 edition of the Journal of the American Medical Association (JAMA). The project uses contemporary technology to tap an ancient and powerful clinical tool—the patient’s own story—as a way to empower and inspire patients, teach empathy and improve health care.
Chemclin’s Anti-TB assay provides components for in-vitro qualitative determination of Antibody to Mycobacterium Tuberculosis (Anti-TB) in human serum or plasma by an indirect chemiluminescent assay method.
Chemclin’s Anti-TP assay provides components for in-vitro qualitative determination of Antibody to Treponema Pallidum (Anti-TP) in human serum or plasma by a double - antigen sandwich chemiluminescent assay method.
Chemclin’s HIV kits are available for in-vitro qualitative determination of Antibody to Human Immunodeficiency Virus Type 1 and Type 2 (Anti-HIV 1+2) and P24 antigen of HIV in human serum or plasma by a sandwich chemiluminescent assay method.
Men do not engage in riskier behaviors after they are circumcised, according to a study in Kenya by University of Illinois at Chicago researchers.
Among uncircumcised men in Kenya, compensation in the form of food vouchers worth approximately U.S. $9 or $15, compared with lesser or no compensation, resulted in a modest increase in the prevalence of circumcision after 2 months, according to a study published by JAMA.
The annual HIV diagnosis rate in the U.S. decreased more than 30 percent from 2002-2011, with declines observed in several key populations, although increases were found among certain age groups of men who have sex with men, especially young men, according to a study in the July 23/30 issue of JAMA, a theme issue on HIV/AIDS.
Among adults in the African country of Malawi offered HIV self-testing, optional home initiation of care compared with standard HIV care resulted in a significant increase in the proportion of adults initiating antiretroviral therapy, according to a study in the July 23/30 issue of JAMA, a theme issue on HIV/AIDS.
HIV-infected patients also infected with hepatitis C virus (HCV) who received a combination of the medications sofosbuvir plus ribavirin had high rates of sustained HCV virologic response 12 weeks after cessation of therapy, according to a study in the July 23/30 issue of JAMA, a theme issue on HIV/AIDS.
Among heterosexual African couples in which the male was HIV positive and the female was not, receipt of antiretroviral pre-exposure preventive (PrEP) therapy did not result in significant differences in pregnancy incidence, birth outcomes, and infant growth compared to females who received placebo, according to a study in the July 23/30 issue of JAMA, a theme issue on HIV/AIDS.
In a preliminary study, HIV-infected patients with excess abdominal fat who received the growth hormone-releasing hormone analog tesamorelin for 6 months experienced modest reductions in liver fat, according to a study in the July 23/30 issue of JAMA, a theme issue on HIV/AIDS.
A multicenter team of researchers report that in a phase III clinical trial, a combination drug therapy cures chronic hepatitis C in the majority of patients co-infected with both HIV and hepatitis C.
New research from UC San Francisco found that 60 percent of the city’s homeless and unstably housed women who are HIV-infected or at high risk to become infected have endured a recent experience of some form of violence.
Douglas Nixon, chair of the Department of Microbiology, Immunology, and Tropical Medicine at the George Washington University School of Medicine and Health Sciences, was published in the Cutting Edge section of the Journal of Immunology for his discovery of an antibody that can neutralize the HIV-1 fossil virus. This may lead to finding a viable immunotherapy option for HIV-1.
The study describes factors believed to contribute to these critical public health issues, with a focus on African American and Latino/Hispanic PLHAs, the racial/ethnic groups most affected by HIV/AIDS.
Scientists may be able to entomb the malaria parasite in a prison of its own making, researchers at Washington University School of Medicine in St. Louis report July 16 in Nature.
HIV, the virus that causes AIDS, has the ability to integrate into the human genome, making it extremely difficult to cure the infection. A new study by scientists at Seattle Children’s Research Institute, University of Washington and Fred Hutchinson Cancer Research Center found that when HIV integrates into genes involved with cancer, these cells tend to reproduce to a greater extent than others HIV-infected cells. The study entitled “Center for Global Infectious Disease Research,” was published on July 10, 2014 in the online edition of the journal Science.
A new study led by Johns Hopkins Bloomberg School of Public Health researchers suggests that getting patients in India quickly evaluated by the right doctors can be just as effective at curbing tuberculosis (TB) as a new, highly accurate screening test.
Kansas State University biochemists have discovered how protein's "hands" enable bacteria to establish infection. The research may help scientists develop targeted treatment and intervention methods.
A University of Kentucky professor and his former student have teamed up to form a company that uses a very unique approach to control a common pest that can carry dangerous diseases.
Scientists have identified a key immune response pathway regulated by zinc that may hold clues to stopping sepsis, one of the leading causes of death in America’s intensive care units.
Doctors have long known that people suffering from influenza are likely to do far worse (or even die) if they get a secondary infection in their lungs or airways. Infection from pneumococcus bacteria, in particular, can lead to pneumonia or a variety of other illnesses that could complicate the recovery of flu sufferers. However, Wistar researchers discovered that pneumococcus often colonizes the respiratory tract without illness and if the order of infection was reversed it could actually protect against severe flu-related illness.
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