Treating rheumatoid arthritis patients with intensive pharmacological agents, such as biologic drugs, may reduce the need for orthopedic joint surgery, according to research presented this week at the American College of Rheumatology Annual Meeting in San Diego.
Tumor necrosis factor inhibitor drugs (commonly called Anti-TNFs) modestly reduce the risk of acute coronary syndrome, such as heart attacks and angina, in rheumatoid arthritis patients whose inflammation places them at higher risk of developing coronary heart disease, according to new research findings presented this week at the American College of Rheumatology Annual Meeting in San Diego.
Patients with rheumatoid arthritis may not need to halt use of their antirheumatic drugs prior to surgery due to fears of increased infection risk, according to research presented this week at the American College of Rheumatology Annual Meeting in San Diego.
Starting with a combination of three traditional disease-modifying antirheumatic drugs (called DMARDs) for treating early rheumatoid arthritis is more cost-effective long term, with comparable benefits, than using either an immediate or step-up approach with anti-tumor necrosis factor (called Anti-TNFs) drugs and methotrexate, according to new research findings presented this week at the American College of Rheumatology Annual Meeting in San Diego.
Using a combination of three traditional disease-modifying antirheumatic drugs for treating recent-onset rheumatoid arthritis is more efficient than a monotherapy approach using methotrexate, according to research presented this week at the American College of Rheumatology Annual Scientific Meeting in San Diego.
Using a combination of three traditional disease-modifying antirheumatic drugs for treating recent-onset rheumatoid arthritis is not only more cost-effective, but results in better long-term worker productivity than a monotherapy approach using methotrexate, according to new research presented this week at the American College of Rheumatology Annual Meeting in San Diego.
A high percentage of rheumatoid arthritis patients discontinue triple therapy, a combination of disease-modifying antirheumatic drugs, after one to two years, according to research presented this week at the American College of Rheumatology Annual Meeting in San Diego.
Medicaid beneficiaries with lupus are not adequately following their treatment plans, and this puts them at risk for poor health outcomes, according to research presented this week at the American College of Rheumatology Annual Meeting in San Diego. For most lupus medications, fewer than one in three beneficiaries were found to be adherent.
According to research presented this week at the American College of Rheumatology Annual Meeting in San Diego, researchers have identified three potentially modifiable risk factors and one protective medication that may improve the health of people living with lupus.
According to research presented this week at the American College of Rheumatology Annual Meeting in San Diego, children born to mothers with lupus may be at twice the risk of autism spectrum disorders than those born to mothers without the disease.
Rituximab (Rituxan®) — a drug commonly used rheumatoid arthritis, granulomatosis with polyangiitis (formerly Wegener’s), and certain types of cancers — may be a safe and effective treatment for immunoglobulin G4-related disease (commonly called IgG4-RD), according to research presented this week at the American College of Rheumatology Annual Meeting in San Diego.
Using Facebook chats to convey health information is becoming more common. A study at Hospital for Special Surgery (HSS) in New York City set out to find the best way to boost participation in the chats to raise awareness of lupus, an autoimmune disease.
Delaying treatment for rheumatoid arthritis could greatly increase the likelihood that patients will suffer joint damage and experience disability two years out, according to a new study from Hospital for Special Surgery.
Pregnant women who have lupus are at increased risk of adverse outcomes. Researchers at Hospital for Special Surgery in New York City have identified a biomarker that may predict who is most at risk.
Lupus prevalence was three times higher than previous estimates, reaching one in 537 black female Michiganders in the region, compared to one in 1,153 white women.
The results of a new study by bone and joint experts at Rush University Medical Center suggest that patients with knee osteoarthritis (OA) who wear flat, flexible footwear, which allows natural foot mobility and provide sufficient support for the foot, had significant reduction in knee loading—the force placed upon the joint during daily activities.
Most everyone is bound to get osteoarthritis -- if they live long enough. That old saying among arthritis experts is backed up by the numbers. The painful and often debilitating joint condition is the most common form of arthritis.
The American Autoimmune Related Diseases Association (AARDA) and Washington University will host an Autoimmune Disease Weekend on the university’s St. Louis campus the first weekend of October.
In Nature Reviews Immunology, William Gause of Rutgers New Jersey Medical School and colleagues have described exciting progress in harnessing the human immune system's reaction to the presence of parasitic worms, as a way to lessen susceptibility to type 1 diabetes and other autoimmune and inflammatory diseases, as well as for use in promoting wound healing.
Scientists from UC San Francisco have identified a new way to manipulate the immune system that may keep it from attacking the body’s own molecules in autoimmune diseases such as type 1 diabetes, rheumatoid arthritis and multiple sclerosis.
A new, large-scale study of more than 2,700 mothers of children with autism shows that about one in 10 mothers have antibodies in their bloodstream that react with proteins in the brain of their babies.
A new study published today in Arthritis Research & Therapy provides the first genomic characterization of remission in juvenile rheumatoid arthritis patients.
A new study of more than 2,700 mothers of children with autism shows that about one in 10 mothers have antibodies in their bloodstream that react with proteins in the brain of their babies.
A research consortium that includes UAB has shown that a new drug for vasculitis, a potentially life-threatening auto-immune disease which causes inflammation in blood vessels, is as effective as standard therapy over 18 months.
• Variants in the gene that encodes ABIN1—which is involved in the control of inflammation—are linked with an increased risk for kidney complications in patients with lupus.
• The finding may point to improved treatments for kidney complications in patients with the disease.
Celiac disease patients with ongoing intestine damage have a greater than 2-fold increased risk of lymphoma vs. celiac patients whose intestines healed. Findings will be published in the Aug. 6 issue of Annals of Internal Medicine.
National Psoriasis Awareness Month being recognized in August, Steve Feldman, a professor of dermatology, pathology and public health sciences at Wake Forest Baptist Medical Center, offers some insight.
St. Jude Children’s Research Hospital study challenges prior understanding of the process regulating specialized T cells that are essential for a balanced immune system
A team led by scientists at The Scripps Research Institute has identified a family of tiny RNA molecules that work as powerful regulators of the immune response in mammals. Mice who lack these RNA molecules lose their normal infection-fighting ability, whereas mice that overproduce them develop a fatal autoimmune syndrome.
Imagine lungs so fragile that a breath of regular room air could result in a lifetime of breathing difficulties, or even death. Each year, as many as 10,000 premature babies face that exact scenario, when the necessary treatments they receive also cause damage to lung tissue, leading to a chronic disease called bronchopulmonary dysplasia (BPD). A closer look at the genes responsible for lung tissue growth in newborns has led scientists to a potential treatment that jumpstarts the lung's natural antioxidant defenses. The gold-based drug has been used for decades as a rheumatoid arthritis treatment.
Two new studies by researchers at Hospital for Special Surgery have shed light on joint replacement outcomes in patients with rheumatoid arthritis (RA).
The painful rheumatic condition gout is often associated with the big toe, but it turns out that patients at highest risk of further flare-ups are those whose gout first involved other joints, such as a knee or elbow, Mayo Clinic has found. The study is among several that Mayo researchers are presenting in Madrid at the European League Against Rheumatism’s annual meeting.
Current immune suppressants have major drawbacks, but a team from The Scripps Research Institute has demonstrated a new technique that may lead to a better way to selectively repress unwanted immune reactions without disabling the immune system as a whole.
Scientists at the National Institutes of Health, and their colleagues, have discovered that a gene called BACH2 may play a central role in the development of diverse allergic and autoimmune diseases, such as multiple sclerosis, asthma, Crohn's disease, celiac disease, and type-1 diabetes.
In a series of lab experiments designed to unravel the workings of a key enzyme widely considered a possible trigger of rheumatoid arthritis, researchers at Johns Hopkins have found that in the most severe cases of the disease, the immune system makes a unique subset of antibodies that have a disease-promoting role.
A Johns Hopkins Children’s Center study in mice may help explain why women are more prone than men to a form of liver damage by implicating the female sex hormone estrogen in the development of autoimmune hepatitis.
People with lupus have a 20 to 50-fold higher rate of cardiac events than a person without lupus, but traditional screening tools are unable to identify or track progressive heart damage caused by the chronic autoimmune disease. Researchers are capturing biomarkers and images of a beating heart during a lupus flare to find out why cardiac disease is so deadly in lupus patients, and provide vital information that may someday help patients avoid devastating cardiac events and survive longer.
Emmy-nominated Actress Kellie Martin Shares Her Story, Calls on Others to Share
New Survey Reveals Need for Increased Awareness/Education of Autoimmune Disease
Workers with rheumatoid arthritis (RA) incur increased direct and indirect health-related costs, reports a study in the March Journal of Occupational and Environmental Medicine, official publication of the American College of Occupational and Environmental Medicine (ACOEM).
Two studies by researchers at UT Southwestern Medical Center could lead to new treatments for lupus and other autoimmune diseases and strengthen current therapies for viral, bacterial, and parasitic infections.
March is National Autoimmune Disease Awareness Month 2013. To mark the annual event, the American Autoimmune Related Diseases Association Inc. (AARDA) is encouraging the national and local media around the country to report stories on autoimmune diseases (AD) and autoimmunity as a category of disease.
Researchers at Hospital for Special Surgery have identified a potential new target for drugs to treat patients with rheumatoid arthritis. Efforts to develop drugs that hone in on this new target are underway.