Jiahn Choi, Michele Houston, Ruixuan Wang, Kenny Ye, Wenge Li, Xusheng Zhang, Derek M Huffman, Leonard H Augenlicht
Stephanie M Kronstadt, Divya B Patel, Louis J Born, Daniel Levy, Max J Lerman, Bhushan Mahadik, Shannon T McLoughlin, Arafat Fasuyi, Lauren Fowlkes, Lauren Hoorens van Heyningen, Amaya Aranda, Sanaz Nourmohammadi Abadchi, Kai-Hua Chang,
Anthony M Kyriakopoulos, Peter A Mccullough, Greg Nigh, Stephanie Seneff
Fu and colleagues profiled a stem cell-derived microfluidic amniotic sac embryoid (μPASE) using single-cell RNA sequencing. Molecular maps of lineage diversifications from the pluripotent human epiblast toward the amniotic ectoderm, primitive streak
We describe hPSC-derived models of FHF, aSHF, and pSHF development spanning the mesoderm, progenitor, and cardiomyocyte stages. Comparison between the hPSC-derived and the corresponding mouse populations revealed conserved developmental trajectories
Xie and colleagues propose a regulatory mechanism of hepatic bile acid metabolism in colitis pathogenesis. They find that the hepatic CYP8B1-cholic acid metabolic axis impairs Lgr5+ intestinal stem cell renewal by repressing PPARα, thus exacerbating
The Act on the Safety of Regenerative Medicine regulates cell-based interventions in Japan. Recent revisions to the law require disclosure of explanatory and consent materials for interventions seeking approval. In this Forum, we present an updated a
A trio of studies in this issue of Cell Stem Cell catalogs the anatomical and functional relationship of intestinal lymphatics with epithelial stem cells, defining an important niche role for the lymphatic endothelium.
In this issue of Cell Stem Cell, Pham et al. report that naive human pluripotent stem cells can be differentiated into extraembryonic mesoderm cells (EXMCs). EXMCs are maintained for up to 70 days, resemble human and monkey extraembryonic mesoderm,
Muscle stem cells (MuSCs) exhibit different metabolic profiles depending on their activity, however the mechanisms by which mitochondria affect MuSC fate has been understudied. In this issue of Cell Stem Cell, Hong et al. (2022) and Baker et al. (2
In this issue of Cell Stem Cell, Yang et al. devise a protocol for induction and differentiation of human heart-field precursors, drawing on inspiration from in vivo development. Intricate computational analyses uncovered conserved factors governin
McKelvey Engineering, School of Medicine collaborate to develop hydrogel system that preserves the biochemistry and mechanical environments of cultured podocyte cells
Drug molecules and biofuels can be made to order by living cell factories, where biological enzymes do the job.
The latest research on plants brought to you by Newswise.
The U.S. Department of Energy (DOE) announced $5 million in funding for research to advance the development of tools that effectively use real-world data—disparate data that is often difficult to readily integrate—into new models (e.g., epidemiology or therapeutic development) in support of bio-preparedness and response studies.
Combining techniques in nanotechnology and optics, researchers produced tiny (nanometric) diamond particles so small that they are capable of penetrating skin to deliver medicinal and cosmetic remedies. In addition, they created a safe, laser-based optical method that quantifies nanodiamond penetration into the various layers of the skin and determines their location and concentration within body tissue in a non-invasive manner – eliminating the need for a biopsy.
Osaka Metropolitan University scientists have developed a simple, rapid method to simultaneously identify multiple food poisoning bacteria, based on color differences in the scattered light by nanometer-scaled organic metal nanohybrid structures (NHs) that bind via antibodies to those bacteria.
Jari Koistinaho, Marja Koskuvi, Elina Pörsti, Ying Chieh Wu, Kalevi Trontti, Amanda McQuade, Ilkka Ojansuu, Tyrone Cannon, Jouko Lönnqvist, Sebastian Therman, Jaana Suvisaari, Jaakko Kaprio, Mathew Blurton-Jones, Iiris Hovatta,
Anna Shirazyan, Haeyoung Park, Ariell M Joiner, Justine Ra, Melissa S Kim, Archana Kumari, Nicole E Franks, Tien Peng, Robert M Bradley, Charlotte M Mistretta, Andrzej A Dlugosz, Benjamin L Allen
Wenbo Jia, Liang Yu, Bin Xu, Yanzhi Feng, Jinyi Wang, Jian Chu, Deming Zhu, Chao Xu, Yongping Zhou, Lianbao Kong, Wenzhou Ding
Zhenwei Zhu, Jingyu Li, Jingxian Liu, Yuan He, Yan Xue, Xiangchan Hong, Zeying Jiang, Dangu Luo, Pei Guo, Kaitai Yao, Lin Chen
Lin-Yi Zhang, Yi-Ying Xiong, Ming-Yan Liao, Xiao Qing, Xiao-Qiong Tang, Luo Xiao-Hua, Hong-Bin Zhang, Wang Li, Liu Lin
Beatriz Parejo-Alonso, Alba Royo-Garcia, Pilar Espiau-Romera, Sarah Courtois, Alvaro Curiel-Garcia, Sladjana Zagorac, Isabel Villaoslada, Kenneth P. Olive, Christopher Heeschen, Patricia Sancho
Yuxing Xia, Tianfan Cheng, Min Zhou, Feiwu Kang, Chongshan Liao
Michael D Moore, Errin Johnson, Chloe Jacklin, Stephen Johnson, Owen Green, William S James
Rene Yu-Hong Cheng, Joseph de Rutte, Andee R Ott, Lucienne Bosler, Wei-Ying Kuo, Jesse Liang, Brian E Hall, David J Rawlings, Dino Di Carlo, Richard G James
Vivian Shang, Jiarong Li, Christopher B Little, Jiao Jiao Li
The latest achievements in the field of pancreas transplantation and stem cell therapy require an effort by the scientific community to clarify the ethical implications of pioneering treatments, often characterized by high complexity from a sur
Arpan De, John M Lattier, John E Morales, Jack R Kelly, Xiaofeng Zheng, Zhihua Chen, Sumod Sebastian, Jason T Huse, Frederick F Lang, Joseph H McCarty
BACKGROUNDThe therapeutic potential of mesenchymal stem cells (MSCs) in the form of three-dimensional spheroids has been extensively demonstrated. The underlying mechanisms for the altered cellular behavior of spheroids have also been investiga
BACKGROUNDImmature dendritic cells (imDCs) play an important role in the induction of donor-specific transplant immunotolerance. However, these cells have limitations, such as rapid maturation and a short lifespan in vivo. In previous studies,
Gianluca Amadei, Charlotte E. Handford, David Glover, Magdalena Zernicka-Goetz
Jongmin J Kim, Emma R Steinson, Mei Sheng Lau, David C Page, Robert E Kingston
Moritz Binder, Terra L. Lasho, Wazim Mohammed Ismail, Nana A. Ben-Crentsil, Jenna A. Fernandez, Minsuk Kim, Susan M. Geyer, Amelia Mazzone, Christy M. Finke, Abhishek A. Mangaonkar, Jeong-Heon Lee, Kwan Hyun Kim, Vernadette A. Simon,
Javier Gilbert, Ujang Purnama, Zoltán Molnár, William S James
Gaspard Jeremie, Fabienne Allias, Alexis Trecourt, Lucie Gaillot-Durand, Pierre-Adrian Bolze, Françoise Descotes, Garance Tondeur, Jimmy Perrot, Touria Hajri, Benoit You, François Golfier, Jonathan Lopez, Mojgan Devouassoux-Shisheboran
Nathalie Chenais, Aurelie LE Cam, Brigitte Guillet, Jean-Jacques Lareyre, Catherine Labbe
Early intervention with bone marrow mesenchymal stem cells to change the form and function of the gut microbiota may help rats regain neurological function after a stroke. Key Words: Ischemic stroke, Bone marrow mesenchymal ste
The NIH announces the winners of the DEBUT Challenge with prizes totaling $130,000
Barney Bryson, Alexandra Kourgiantaki, Dai Jiang, Andreas Demosthenous, Linda Greensmith
Bogdan B Grigorash, Dominic van Essen, Laurent Grosse, Alexander Emelyanov, Benoit Kanzler, Clement Molina, Elsa Lopez, Oleg N Demidov, Carmen Garrido, Simona Saccani, Dmitry Bulavin
Jun Cui, Joseph S Carey, Renee A Reijo Pera
Mohammad Kamalabadi Farahani, Roqaye Karimi, Amir Atashi
Yuxi Ma, Yongyou Zhu, Li Shang, Yan Qiu, Na Shen, Qingxuan Song, Jun Li, Max S. Wicha, Ming Luo
Lisa Nguyen, Michelle Westerhoff, Leonie Thewes, Wasco Wruck, Andreas S Reichert, Carsten Berndt, James Adjaye
Betul Cicek, Serhat Hayme, Mehmet Kuzucu, Ahmet Cetin, Yesim Yeni, Sidika Genc, Serkan Yildirim, Ismail Bolat, Mecit Kantarci, Mustafa Gul, Ahmet Hacimuftuoglu
Jing Yang, Na Yang, Huifang Zhao, Yan Qiao, Yanqiu Li, Chunfang Wang, Kah-Leong Lim, Chengwu Zhang, Wulin Yang, Li Lu
K. S. Bagdassarian, J. P. Etchells, N. S. Savage
Rolando A Cuevas, Luis Hortells, Claire Chu, Ryan Wong, Alex Crane, Camille Boufford, Caylin Regan, William Moorhead, Michael Bashline, Aneesha Parwal, Angeline Parise, Aditi Gurkar, Dennis Bruemmer, John Sembrat,
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