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Medicine

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Toronto Rehab Scientists Discover Environmental Enrichment for TBI Patients May Counter Shrinkage in the Brain

For the first time, scientists at Toronto Rehab have found that in people with chronic moderate-severe traumatic brain injury (TBI), atrophy (shrinkage) in the brain may be countered by participating in environmental enrichment – increased physical, social and cognitive stimulation.

Medicine

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Cancer, Pancreatic Cancer, abramson cancer center, Perelman School of Medicine at the University of Pennsylvania, Clinical Trials

Penn Medicine Researchers Harness the Immune System to Fight Pancreatic Cancer

Pancreatic cancer ranks as the fourth-leading cause of cancer death in the United States, and is one of the most deadly forms of cancer, due to its resistance to standard treatments with chemotherapy and radiation therapy and frequently, its late stage at the time of diagnosis. A group of researchers led by the University of Pennsylvania’s Perelman School of Medicine and Abramson Cancer Center, in collaboration with scientists from the University of Pittsburgh and University of Washington, published results of a clinical trial in which the standard chemotherapy drug for this disease, gemcitabine, was paired with an agonist CD40 antibody, resulting in substantial tumor regressions among some patients with advanced pancreatic cancer. By using a novel, real-time imaging approach to monitor tumor response to the immunotherapy, the team also found differences how primary and metastatic disease sites shrank. Their work appears online this month in Clinical Cancer Research.

Science

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Fusion, National Ignition Facility, NIF, Lawrence Livermore National Laboratory, LLNL, Department Of Energy, hohlraum , M.J. Edwards , General Atomics, Massachusetts Institute Of Technology, University Of Rochester, Los Alamos National Laboratory, Sandia National Laboratory, AIP

Fusion, Anyone?

800px-Preamplifier_at_the_National_Ignition_Facility.jpg

The dream of igniting a self-sustained fusion reaction with high yields of energy, a feat likened to creating a miniature star on Earth, is getting closer to becoming reality, according the authors of a new review article in the journal Physics of Plasmas.

Medicine

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fat grafting, Scarring Problems, The Journal of Craniofacial Surgery

Fat Grafting Helps Patients with Scarring Problems, ReportsThe Journal of Craniofacial Surgery

Millions of people with scars suffer from pain, discomfort, and inability to perform regular activities. Some may have to revert to addicting pain medicine to get rid of their ailments. Now, and with a new methodology, such problems can be treated successfully. A technique using injection of the patient's own fat cells is an effective treatment for hard, contracted scars resulting from burns or other causes, reports a study in the September issue of The Journal of Craniofacial Surgery, edited by Mutaz B. Habal, MD, FRCSC, and published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

Science

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Biofuels, Alternative Energy, climatic change, Agriculture

Time to Rethink Misguided Policies That Promote Biofuels to Protect Climate

Policymakers need to rethink the idea of promoting biofuels to protect the climate because the methods used to justify such policies are inherently flawed, according to a University of Michigan energy researcher.

Medicine

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Genomics, Genomic Medicine, Genetics, Genomic Research, Electronic Health Record, Pennsylvania, Human Genetics, Human Genome Project

Geisinger Genomics Director Says EHRs Key to Effective use of Genetic Information

Insights of several research teams actively engaged in integrating genomic medicine into the electronic health record are featured in the October 2013 issue of Genetics in Medicine.

Science

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candida infection, V-ATPase, Rajini Rao

Scientists Discover Possible Way To Turn Fungus From Foe To Friend

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Candida albicans is a double agent: In most of us, it lives peacefully, but for people whose immune systems are compromised by HIV or other severe illnesses, it is frequently deadly. Now a new study from Johns Hopkins and Harvard Medical School shows how targeting a specific fungal component might turn the fungus from a lion back into a kitten.

Medicine

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Sudden Cardiac Death, Sudden Cardiac Arrest, implantable cardiac defibrillator, Oregon Sudden Unexpected Death Study, Heart Institute, Sumeet Chugh

Majority of Patients Who Qualify for Lifesaving Heart Treatment Do Not Receive It

A new study of patients who died of sudden cardiac arrest, a usually fatal condition that causes the heart to stop beating, shows the majority who qualified to receive potentially lifesaving treatment did not receive it.

Medicine

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Pregnancy, Influenza, H1N1, Vaccines, Vaccination, Flu Shot, Obstetrics

Reassuring Findings for Mothers Who Have Flu Shot in Pregnancy

Researchers from the University of California, San Diego School of Medicine and Boston University, in collaboration with the American Academy of Allergy Asthma and Immunology (AAAAI), have found evidence of the H1N1 influenza vaccine’s safety during pregnancy.

Medicine

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Ciclopirox, HIV, Mitochondria, Mathews, Hanauske-Abel, Rutgers Biomedical and Health Sciences, Deferiprone, anti-fungal, New Jersey Medical School

Drug is Found to Eradicate HIV Permanently from Infected Cells

The anti-fungal drug Ciclopirox causes HIV-infected cells to commit suicide by jamming up the cells’ powerhouse, the mitochondria, according to a study by researchers at Rutgers New Jersey Medical School. And unlike current anti-HIV drugs, Ciclopirox completely eradicates infectious HIV from cell cultures, with no rebound of virus when the drug is stopped.







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