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Researchers Find a Way to Improve Memory by Suppressing a Molecule That Links Aging to Alzheimer’s Disease

Researchers find a way to improve memory by suppressing a molecule that links aging to Alzheimer’s disease

Medicine

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ALS, Amyotrophic Lateral Sclerosis, Lou Gehrig's Disease, Motor Neurons, Clive Svendsen

Cedars-Sinai Study of Lou Gehrig’s Disease Shifts ‘Origin’ Focus to Brain’s Motor Neurons

Lou Gehrig’s disease, also known as amyotrophic lateral sclerosis, or ALS, might damage muscle-controlling nerve cells in the brain earlier in the disease process than previously known, according to research from the Cedars-Sinai Board of Governors Regenerative Medicine Institute. The findings, published in the Nov. 12 Journal of Neuroscience, could shift researchers’ attention from the spinal cord to the brain’s motor cortex as the disease’s initial point of dysfunction.

Medicine

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Michael Long, Nyu Langone, Songbird, Epilepsy, Brain Cancer, Brain Tumor, Brain Mapping, Speech, Zebra Finch

Songbirds Help Scientists Develop Cooling Technique to Safely Map the Human Brain

A new diagnostic technique — resulting from monitoring thousands of courtship calls from songbirds — can be used to safely map the human brain during complex neurosurgery, according to research from Neuroscientists at NYU Langone Medical Center and elsewhere.

Science

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Protein Misfolding, Cystic Fibrosis, Alzheimer's Disease, CFTR gene, chaperone molecules, HSF1, Cell Biology

Cells’ Natural Response to Chronic Protein Misfolding May Do More Harm than Good

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Protein misfolding” diseases such as cystic fibrosis and Alzheimer’s may be seriously exacerbated by the body’s own response against that misfolding, according to a new study led by scientists at The Scripps Research Institute.

Medicine

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Nyu Langone, Regina Sullivan, Maternal And Child Health, Neurodevelopment, Nurture

A Mother's Soothing Presence Makes Pain Go Away – and Changes Gene Activity in the Infant Brain

A mother’s “TLC” not only can help soothe pain in infants, but it may also impact early brain development by altering gene activity in a part of the brain involved in emotions, according to new study from NYU Langone Medical Center.

Medicine

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Alzheimer's Disease, Oxidative Stress, Free Radicals, Thromboxane Receptor, Amyloid Beta, Tau Phosphorylation, neuronal cells

Brain Receptor Cell Could Be New Target for Alzheimer’s

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Blocking a key receptor in brain cells that is used by oxygen free radicals could play a major role in neutralizing the biological consequences of Alzheimer’s disease, according to researchers at Temple University.

Medicine

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Subarachnoid Hemorrhage, Ruptured Aneurysm, Protocol, ultra-early treatment, patient outcomes

A Formal Protocol for Ultra-Early Treatment of Aneurysmal Subarachnoid Hemorrhage

A formal protocol for delivering emergency treatment to patients with subarachnoid hemorrhage (SAH) from ruptured aneurysms within the first few hours after bleeding occurs. Offered day and night, the protocol reduces the incidence of repeated hemorrhage during the hospital stay and improves clinical outcomes in patients with aneurysmal SAH.

Science

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Brain Science, University of Washington

Major Brain Pathway Rediscovered After Century-Old Confusion, Controversy

A scientist looking at MRI scans of human brains noticed a large fiber pathway that seemed to be part of the network that processes visual information. He just couldn’t couldn’t find it in any of the modern textbooks.

Medicine

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spinal cord injury research, ventilator assisted breathing, breathing muscle paralysis, Chondroitinase, intermittent hypoxia, breathing restoration

Laboratory Breakthrough Offers Promise for Spinal Cord Injury Patients to Breathe on Their Own Again

Case Western Reserve researchers have developed a procedure that restores function to muscles that control breathing – even when they have been paralyzed for more than a year. The breakthrough offers hope that patients with severe spinal cord injuries will be able to breathe again on their own.

Medicine

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Calorie Restriction, Diet, Nyu Langone, Stephen Ginsberg, Aging, Gene Expression

Calorie-Restricting Diets Slow Aging, Study Finds

Neuroscientists at NYU Langone Medical Center have shown that calorie-reduced diets stop the normal rise and fall in activity levels of close to 900 different genes linked to aging and memory formation in the brain.







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