Penn medicine researchers find much stronger association between alcohol use and advanced liver fibrosis in co-infected patients compared to uninfected
Women should refrain from drinking alcohol before they try to become pregnant, according to maternal-fetal medicine specialists at Loyola University Health System.
In mice, a drug produces evidence of a mood lift within 24 hours and then continues working for sustained depression relief. A fast-acting antidepressant would be a welcome development for patients who must wait weeks for current drugs to take effect.
Scientists successfully cure mice of acute liver failure after an overdose of acetaminophen, the active ingredient in Tylenol and one of the most commonly used drugs in the United States, by boosting the liver’s ability to heal itself.
Study conducted in rats offers clues about how teen drinking alters brain chemistry, suggesting early alcohol use has long-term effects on decision making.
Researchers have found a common link between muscle weakness in alcoholics and mitochondrial disease: mitochondria that are unable to self-repair. The research could lead to both a new diagnostics for mitochondrial disease and a new drug target.
Binge drinking by teenagers and young adults is strongly associated with liking, owning, and correctly identifying music that references alcohol by brand name according to a study by the University of Pittsburgh and Dartmouth-Hitchcock Norris Cotton Cancer Center.
A study is providing new insights into why binge drinking has such a negative effect on wound healing. Binge alcohol exposure significantly reduced levels of key components of the immune system involved in healing, the study found.
Much has been reported about the potential for increased risk of alcohol misuse after weight loss surgery (WLS), with most theories pointing to lower alcohol tolerance and a longer time to return to a sober state after surgery, but a new study from Beth Israel Deaconess Medical Center suggests that upwards of half of high-risk drinkers are actually less likely to report high-risk drinking behavior after weight loss surgery.
University of Utah neuroscientists report that when a region of the brain called the lateral habenula is chronically inactivated in rats, they repeatedly drink to excess and are less able to learn from the experience. The study, published online in PLOS ONE on April 2, has implications for understanding behaviors that drive alcohol addiction.
If signed into law, Maryland will join the ranks of over a dozen other states that ban the sale of such products, including Pennsylvania, West Virginia, and Virginia.
A team of researchers from the National University of Singapore (NUS) has developed the world’s first fluorescent sensor to identify the presence of a drug known as GHB that is commonly used to spike beverages. When the sensor is mixed with a sample of a beverage containing GHB, the mixture changes colour in less than 30 seconds, making detection of the drug fast and easy.
Researchers at the University of California, San Diego School of Medicine have discovered impaired neuronal activity in the parts of the brain associated with anticipatory functioning among occasional 18- to 24-year-old users of stimulant drugs, such as cocaine, amphetamines and prescription drugs such as Adderall.
A new guideline from the American Academy of Neurology suggests that there is little evidence that most complementary or alternative medicine therapies (CAM) treat the symptoms of multiple sclerosis (MS). However, the guideline states the CAM therapies oral cannabis, or medical marijuana pills, and oral medical marijuana spray may ease patients’ reported symptoms of spasticity, pain related to spasticity and frequent urination in multiple sclerosis (MS). The guideline, which is published in the March 25, 2014, print issue of Neurology®, the medical journal of the American Academy of Neurology, states that there is not enough evidence to show whether smoking marijuana is helpful in treating MS symptoms.
Youth are not merely mimicking the alcohol brand choices of adults, suggesting that other factors may influence their drinking preferences. This is the conclusion of a new report comparing the alcohol brand preferences of underage drinkers and adults from the Boston University School of Public Health and the Center on Alcohol Marketing and Youth (CAMY) at the Johns Hopkins Bloomberg School of Public Health.
Addictive behavior such as drug and alcohol abuse could be associated with poor development of the so-called "love hormone" system in our bodies during early childhood, according to researchers at the University of Adelaide.
A study published in the International Journal of Drug Policy by researchers affiliated with New York University’s Center for Drug Use and HIV Research (CDUHR), finds large proportions of high school students normally at low risk for marijuana use (e.g., non-cigarette-smokers, religious students, those with friends who disapprove of use) reported intention to use marijuana if it were legal.
You may have only had one glass of wine with dinner, but if you’re 55 or older, that single serving may hit you hard enough to make you a dangerous driver.
Amid times of crisis, citizens often turn to social media as a method to share information, make observations and vent. But as a Georgia Tech professor’s research into social media use amid the Mexican drug war shows, posts can reveal growing numbness, or desensitization, during times of protracted violence and stress.
Texans, known for enjoying local beers and Dr Pepper soft drinks, now have a growing beverage industry that would appeal to James Bond, who is well-known for enjoying a good martini. Distillers are producing at least 17 Texas vodkas, researchers reported here today at the 247th National Meeting & Exposition of the American Chemical Society. The most popular are, surprisingly, those that are a bit salty.
While the world’s best athletes competed during last month’s winter Olympics, doctors and scientists were waging a different battle behind the scenes to make sure no one had an unfair advantage from banned performance-enhancing drugs. Here today at the 247th National Meeting & Exposition of the American Chemical Society, researchers unveiled a new weapon — a test for doping compounds that is a thousand times more sensitive than those used today.
Leftover cigarette smoke that clings to walls and furniture is a smelly nuisance, but now research suggests that it could pose a far more serious threat, especially to young children who put toys and other smoke-affected items into their mouths. Scientists reported today at the 247th National Meeting & Exposition of the American Chemical Society that one of the tobacco-specific nitrosamines newly formed in “third-hand smoke” damages DNA and could potentially cause cancer.
Heavy alcohol consumption is common in the United States and takes a personal and societal toll, with an annual estimated cost of $223.5 billion. Researchers at Penn Medicine have shown that the anticonvulsant medication, topiramate, previously shown to reduce drinking in patients committed to abstinence from alcohol, can also be helpful in treating problem drinkers whose aim is to curb their alcohol consumption – particularly among a specific group of patients whose genetic makeup appears to be linked to the efficacy of the therapy. Their findings are published in the current issue of the American Journal of Psychiatry.
Not only is heroin addictive and deadly, its use is increasing among Americans. That disturbing trend parallels the spike of opioid based prescription painkiller abuse in recent years, say Mayo Clinic experts.
In the wake of actor Philip Seymour Hoffman’s death, Loyola University Health System toxicologist Christina Hantsch, MD, FACEP, FACMT, is available to talk about the rise she has seen in heroin overdoses in recent years.
A new study correlating brain activity with how people make decisions suggests that when individuals engage in risky behavior, such as drunk driving or unsafe sex, it’s probably not because their brains’ desire systems are too active, but because their self-control systems are not active enough. This might have implications for how health experts treat mental illness and addiction or how the legal system assesses a criminal’s likelihood of committing another crime.
Research among college students found that men under the influence of alcohol are more likely to perpetrate physical, psychological or sexual aggression against their partners than men under the influence of marijuana. Women, on the other hand, were more likely to be physically and psychologically aggressive under the influence of alcohol but, unlike men, they were also more likely to be psychologically aggressive under the influence of marijuana.
In laboratory experiments conducted on human cell lines at the Johns Hopkins Kimmel Cancer Center, scientists have shown that people carrying certain mutations in two hereditary cancer genes, BRCA2 and PALB2, may have a higher than usual susceptibility to DNA damage caused by a byproduct of alcohol, called acetaldehyde.
Teen marijuana use may have repercussions in unexposed progeny. This rodent study found that parental use of marijuana/THC was linked to molecular and neurobiological disturbances and increased motivation to get drugs.
Finding suitable drug targets for treating cocaine addiction has proved daunting, but for the first time, researchers have shown that abundant enzyme PARP-1 and the sidekick-1 gene are found to enhance the brain's reward system.
The estimated 9 percent of college students who have symptoms of PTSD are likely to drink more alcohol than peers without the psychological condition. In turn, heavy alcohol consumption exacerbates their PTSD symptoms.
UC San Diego study finds that even "minimally buzzed" drivers - BAC 0.01 percent - are 46 percent more likely to be officially and solely blamed by accident investigators than are the sober drivers they collide with.
TORONTO, ON – Remission from depression is delayed in adults who have experienced childhood physical abuse or parental addictions, a new study by University of Toronto researchers has found. The study is published this week in the journal Social Psychiatry and Psychiatric Epidemiology.
University of Toronto investigators examined a range of factors associated with remission in a sample of 1,128 depressed Canadian adults, drawn from the National Population Health Survey. Depressed individuals were followed every other year until remission occurred, for up to 12 years. “Our findings indicated that most people bounce back. In fact, three-quarters of individuals were no longer depressed after two years” reported co-author and Professor Emeriti Tahany M. Gadalla. However, not everyone recovered at the same rate.
Middle-aged men who drink more than 36 grams of alcohol, or two and a half US drinks per day, may speed their memory loss by up to six years later on, according to a study published in the January 15, 2014, online issue of Neurology®, the medical journal of the American Academy of Neurology. On the other hand, the study found no differences in memory and executive function in men who do not drink, former drinkers and light or moderate drinkers. Executive function deals with attention and reasoning skills in achieving a goal.
Researchers at the University at Buffalo have found a way to change alcohol drinking behavior in rodents, using the emerging technique of optogenetics, which uses light to stimulate neurons.
Des Plaines, IL - Researchers from the University of Wisconsin-Milwaukee and USDTL (United States Drug Testing Laboratory, Inc.) have published study results in the OpenOnline edition of the journal Addiction demonstrating the use of the direct alcohol biomarker ethyl glucuronide (EtG).
Researchers at Washington University School of Medicine in St. Louis and the University of Southern California have found that rates of smoking, drinking and drug use are significantly higher among those who have psychotic disorders than among those in the general population. The finding is of particular concern because individuals with severe mental illness are more likely to die younger than people without severe psychiatric disorders.
The potential for misuse of prescription drugs and alcohol during the holidays increases because of social gatherings, tradition and travel, so public health experts at the Indiana University School of Public Health-Bloomington have a simple message: lock up your Rx drugs and be mindful of the amount of alcohol you consume and make available.
In this month’s release find research about local smoke-free laws’ impact on asthma; patterns of alcohol-use among sexual minority adolescents; recommendations to reduce military sexual trauma; and how political leanings may impact cigarette tax rates more than the economy.
Fewer high school students across the U.S. started drinking alcohol, smoking cigarettes, committing crimes and engaging in violence before graduation when their towns used the Communities That Care prevention system during the teens' middle school years. A University of Washington study found that the positive influence of this community-led system was sustained through high school.
States with a higher number of alcohol- and traffic-related laws have a lower proportion of traffic deaths than do states with fewer such laws on the books, a study by researchers at NYU’s Steinhardt School of Culture, Education, and Human Development has found.
The use of crack and powder cocaine both varies and overlaps among high school seniors, researchers at NYU and NYU Langone Medical Center have found. Their findings point to the need to take into account both common and different at-risk factors in developing programming and messaging to stem cocaine use.