Feature Channels: Respiratory Diseases and Disorders

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Released: 11-Jun-2020 7:00 AM EDT
Lung Transplant Performed on a COVID-19 Patient at Northwestern Medicine
Northwestern Medicine

For the first time, surgeons at Northwestern Medicine performed a double-lung transplant on a patient whose lungs were damaged by COVID-19. The patient, a Hispanic woman in her 20s, spent six weeks in the COVID ICU on a ventilator and extracorporeal membrane oxygenation (ECMO), a life support machine that does the work of the heart and lungs.

8-Jun-2020 11:05 AM EDT
Biohybrid Model Uses Organic Lungs, Synthetic Muscles to Re-Create Respiration Mechanics
American Institute of Physics (AIP)

Discussed in APL Bioengineering, researchers created a high-fidelity respiratory simulator that accurately represents the interplay between the abdomen, diaphragm, lungs and pleural space, the fluid-filled membrane surrounding the thorax and lungs. The model, using swine lungs, soft robotic materials and artificial muscles, allows precise tuning of pressure in each part of the system, so specific disease conditions can be tested. It also proved extremely useful for testing ventilator-only respiration by removing the elastomeric diaphragm.

Released: 8-Jun-2020 12:55 PM EDT
Reducing severe breathlessness and psychological trauma in COVID-19 ARDS patients
Beth Israel Lahey Health

A new Viewpoint article published online in the Annals of the American Thoracic Society examines ventilation and medication strategies that can help avoid psychological trauma for severe COVID-19 survivors treated for acute respiratory distress syndrome (ARDS) with mechanical ventilation.

2-Jun-2020 8:00 AM EDT
Reducing Severe Breathlessness and Psychological Trauma in COVID-19 ARDS Survivors
American Thoracic Society (ATS)

A new paper published online in the Annals of the American Thoracic Society examines ventilation and medication strategies that can help avoid psychological trauma for severe COVID-19 survivors treated for acute respiratory distress syndrome (ARDS) with mechanical ventilation.

Released: 2-Jun-2020 3:10 PM EDT
Pulmonary Embolism and COVID-19
Henry Ford Health

Researchers at Henry Ford Health System in Detroit say early diagnosis of a life-threatening blood clot in the lungs led to swifter treatment intervention in COVID-19 patients. In a new study published recently in the journal Radiology, researchers found that 51 percent of patients found to have a pulmonary embolism, or PE, were diagnosed in the Emergency Department, the entry point for patients being admitted to the hospital.

Released: 1-Jun-2020 4:55 PM EDT
Researchers Map SARS-CoV-2 Infection in Cells of Nasal Cavity, Bronchia, Lungs
University of North Carolina School of Medicine

UNC-Chapel Hill researchers show how SARS-CoV-2 infects the nasal cavity to a great degree, and progressively less so lower down the respiratory tract, suggesting the virus tends to become firmly established first in the nasal cavity, but can be aspirated into the lungs to cause serious disease.

Released: 29-May-2020 11:40 PM EDT
Study finds overwhelming support for smoke-free policies among Los Angeles tenants, landlords
UCLA Fielding School of Public Health

Half of apartment dwellers in Los Angeles report having been exposed to unwanted secondhand smoke in their homes in the last year, and 9 in 10 of them say they favor policies banning smoking from their buildings, a new study by researchers at the Fielding School of Public Health's UCLA Center for Health Policy Research reveals.

Released: 29-May-2020 4:55 PM EDT
CT findings of coronavirus disease (COVID-19) in children 'often negative'
American Roentgen Ray Society (ARRS)

An investigation published open-access in the American Journal of Roentgenology (AJR) revealed a high frequency of negative chest CT findings among pediatric patients with laboratory-confirmed coronavirus disease (COVID-19), while also suggesting that bilateral, lower lobe-predominant ground-glass opacities (GGOs) are common in the subset of patients with positive CT findings.

Released: 27-May-2020 8:00 AM EDT
Analysis Does Not Find Two Distinct Subphenotypes of COVID-19 Related ARDS
American Thoracic Society (ATS)

In a new paper published online in the Annals of the American Thoracic Society, researchers have been unable to produce two theorized subphenotypes of COVID-19 related acute respiratory distress syndrome (ARDS). Scientists previously proposed that two phenotypes exist that differentiate patients with more severe COVID-19 and indicate that they should be treated differently. A phenotype is a set of characteristics used to classify a patient, which may influence disease management.

Released: 26-May-2020 3:45 PM EDT
Humans have beneficial bacteria uniquely adapted for life in our noses
Cell Press

Beneficial strains of bacteria residing in our guts, genital tracts, and skin have been shown to play a role in human health, and now, researchers publishing May 26 in the journal Cell Reports suggest that some of these "good" bacteria also have a niche in our noses

Released: 26-May-2020 11:45 AM EDT
Health System in Pandemic Epicenter Identifies Outcomes and New Risk Factors of Patients Hospitalized with COVID-19
NYU Langone Health

A team of investigators at NYU Langone Health determined that just over half of 5,279 patients who tested positive for COVID-19 were hospitalized -- and nearly a quarter of those hospitalized died or were discharged to hospice, including 60 percent who required ventilators.

19-May-2020 11:25 AM EDT
Patients with COVID-19 may develop thyroid infection
Endocrine Society

COVID-19 infection may cause subacute thyroiditis, according to a new case study published in The Journal of Clinical Endocrinology & Metabolism.

Released: 19-May-2020 3:45 PM EDT
High rate of blood clots in COVID-19
University of Sussex

COVID-19 is associated with a high incidence of venous thromboembolism, blood clots in the venous circulation, according to a study conducted by researchers at Brighton and Sussex Medical School (BSMS), UK.

Released: 19-May-2020 12:05 PM EDT
Children Not Immune to Coronavirus; New Study from Pandemic Epicenter Describes Severe COVID-19 Response in Children
Albert Einstein College of Medicine

While most children infected with the novel coronavirus have mild symptoms, a subset requires hospitalization and a small number require intensive care. A new report from pediatric anesthesiologists, infectious disease specialists and pediatricians at the Children’s Hospital at Montefiore (CHAM) and Albert Einstein College of Medicine, describes the clinical characteristics and outcomes of children hospitalized with COVID-19, during the early days of the pandemic.

Released: 14-May-2020 4:25 PM EDT
New CAP Guideline Improves Collection, Handling of Lung Specimens
College of American Pathologists (CAP)

The College of American Pathologists (CAP) released a new evidence- based guideline “Collection and Handling of Thoracic Small Biopsy and Cytology Specimens for Ancillary Studies” to clarify procedures and methods to optimize test outcomes.

Released: 14-May-2020 3:40 PM EDT
Coronavirus outbreak trending topics - See the Coronavirus Channel
Newswise

Research and experts on the symptoms and spread of COVID-19, impact on global trade and financial markets, public health response, search for an effective treatment, and more

       
13-May-2020 2:15 PM EDT
Chest X-Rays in Emergency Rooms Can Help Predict Severity of COVID-19 Illness in Young and Middle-aged Adults
Mount Sinai Health System

Chest X-rays performed on young and middle-aged adults with COVID-19 when they arrive at the emergency room can help doctors predict who is at higher risk of severe illness and intubation, Mount Sinai researchers report.

11-May-2020 3:55 PM EDT
Blood Test Indicators of Infection Response Do Not Generally Predict Severity of Community-Acquired Pneumonia in Children
Ann and Robert H. Lurie Children's Hospital of Chicago

Blood biomarkers that reflect the body’s response to infection – including white blood cell count, absolute neutrophil count, C-reactive protein (CRP) and procalcitonin – are generally not useful in predicting the overall severity of community-acquired pneumonia in children, according to a study published in Pediatrics.

8-May-2020 2:10 PM EDT
Sanford Burnham Prebys to develop broad-spectrum antivirals with $10 million Department of Defense grant
Sanford Burnham Prebys

Sanford Burnham Prebys Medical Discovery Institute is pleased to announce that Sumit Chanda, Ph.D., has received a $10.2 million, four-year grant from the Department of Defense to develop and advance broad-spectrum antivirals for respiratory diseases. The award aims to provide U.S. military forces and the nation with safe, effective and innovative therapies that combat multiple types of respiratory viruses.

Released: 5-May-2020 2:00 PM EDT
COVID-19 and the Challenging Acute Respiratory Distress Syndrome (ARDS)
Aqualung Therapeutics

Joe G. N. "Skip" Garcia, MD, an academic pulmonary physician-scientist describes a complication in COVID-19.

Released: 5-May-2020 10:00 AM EDT
ATS Announces GSK Grants to Support COVID-19 Crisis Fund’s Research and Outreach Efforts
American Thoracic Society (ATS)

Today, the American Thoracic Society announced that GlaxoSmithKline (GSK) has awarded the Society two grants totaling $380,000 to support the ATS COVID-19 Crisis Fund, a newly launched initiative to develop and disseminate research, education and scientific recommendations to providers in the pulmonary and critical care communities, as well as other clinicians in need of expanding their skill set during this emergency. The first grant will fund two new $50,000 grants in the ATS Research Program in COVID-19. The second grant for $280,000 will support the Society’s patient education and outreach efforts related to COVID-19.

Released: 4-May-2020 7:00 AM EDT
Fibrosis or Pulmonary Fibrosis? COVID-19 Coverage Leads to Confusion
Pulmonary Fibrosis Foundation

Many reports have included pulmonary fibrosis as a potential consequence of COVID-19. Data shows some COVID-19 patients develop scarring on the lungs – but not necessarily chronic pulmonary fibrosis or interstitial lung disease, which are characterized by progressive scarring.

29-Apr-2020 4:30 PM EDT
Simulation-based Training Helps Providers Prepare forProne Position Ventilation for Patients With ARDS
American Association of Critical-Care Nurses (AACN)

An interprofessional simulation-based educational program helped Mount Sinai Hospital train nearly 90% of its medical ICU staff to care for patients in prone position, as part of its 2018 implementation of a new protocol related to prone position ventilation for patients with acute respiratory distress syndrome.

Released: 1-May-2020 4:40 PM EDT
VIDEO AND TRANSCRIPT AVAILABLE: Newswise Live Expert Panel for April 30, 2020: New tech from engineers, assessing the recession
Newswise

Newswise Live Expert Panel for April 30, 2020: New tech from engineers, assessing the recession

       
27-Apr-2020 9:00 AM EDT
Long-Lasting, Low Toxicity Antimicrobial Peptide Fights ‘Superbug’ Lung Infections
Health Sciences at the University of Pittsburgh

Through serendipity, researchers at the University of Pittsburgh Graduate School of Public Health considerably reduced the toxicity of a potential antibiotic against the most feared drug-resistant bacteria, while also improving its stability in fighting infections.

Released: 30-Apr-2020 8:00 AM EDT
Clinicians Warn of the Dangers of Equating COVID-19 with High Altitude Pulmonary Edema
American Thoracic Society (ATS)

Early reports of COVID-19 symptoms and the compelling need to quickly identify treatment options and curb the growing number of critically ill patients have led to erroneous and potentially dangerous comparisons between COVID-19 and other respiratory diseases like high altitude pulmonary edema, or HAPE.

Released: 27-Apr-2020 9:00 AM EDT
Can Vaping Scar Your Lungs? New Insights and a Possible Remedy
Federation of American Societies for Experimental Biology (FASEB)

Researchers report evidence that the compounds in e-cigarette liquid could potentially cause the body’s tissue repair process to go haywire and lead to scarring inside the lungs.

Released: 27-Apr-2020 9:00 AM EDT
Breathing During Exercise Is Harder for Women Than Men
Federation of American Societies for Experimental Biology (FASEB)

While both sexes have the capacity for phenomenal athletic achievements, women on average must work harder to breathe during strenuous exercise compared to men, according to new research.

Released: 24-Apr-2020 8:40 AM EDT
When Ventilators Don’t Help COVID-19 Patients, This Might
Michigan Medicine - University of Michigan

Ventilators have gotten a lot of attention in the ongoing fight against COVID-19. But hundreds of hospitals around the world have another, less-publicized weapon that might help some of the most desperately ill patients survive when ventilators aren’t enough. It's called ECMO.

Released: 24-Apr-2020 8:20 AM EDT
A Mayo Clinic faz um aviso urgente sobre a abordagem para se identificar pacientes com risco de morte súbita cardíaca induzida por uso de medicamentos off label para o tratamento do COVID-19
Mayo Clinic

O SARS-CoV-2, o vírus que causa o COVID-19, continua a se espalhar, levando a mais de 20.000 mortes em todo o mundo em menos de quatro meses. Esforços estão progredindo para desenvolver uma vacina para o COVID-19, mas é provável que isso ainda leve de 12 a 18 meses.

20-Apr-2020 5:05 AM EDT
Investigators Experiment with Differing Amounts of Anesthetic to Provide Pain Control during Shoulder Surgery and Reduce Chances for Respiratory Complications
American Society of Regional Anesthesia and Pain Medicine (ASRA)

Hemidiaphragmatic paresis, or HDP, is a condition in which one side of the diaphragm is weakened, resulting in shortness of breath and reduced respiratory function. It can occur when a patient is given regional anesthesia for shoulder surgery, using the supraclavicular nerve block. Researchers are trying to determine the right amount of anesthesia to use in the supraclavicular block so that the block still works but the chances of developing HDP are low.

Released: 22-Apr-2020 10:05 AM EDT
Series of Rare Right-Colon Twists Highlights Need for Doctor Vigilance with New, Targeted Anti-Cancer Drugs
University of Colorado Cancer Center

Study: with smaller clinical trials, it may be up to doctors to notice rare drug side effects

Released: 20-Apr-2020 5:20 PM EDT
COVID-19 treatment depends upon disease severity
Cornell University

How individuals, and health care professionals, deal with infection from SARS-CoV-2, the virus that causes COVID-19, varies depending on the severity of the infection.

Released: 20-Apr-2020 3:35 PM EDT
First Official ATS Practice Guidelines for Sarcoidosis Cover Diagnosis and Detection
American Thoracic Society (ATS)

New guidance is available for physicians who must go through a number of steps to provide a probable diagnosis of sarcoidosis – an inflammatory disease that affects the lungs, lymph glands, and other organs.

20-Apr-2020 8:45 AM EDT
Undergraduate-Led Team Develops Low-Cost Ventilator Aimed at Assisting COVID-19 Patients with Varying Degrees of Lung Failure
New York University

A team of university students and engineers has developed a low-cost ventilator using off-the-shelf components that is designed to aid patients with varying degrees of lung failure.

Released: 17-Apr-2020 5:10 PM EDT
First COVID-19 patient in Texas enrolled in UTHealth stem cell therapy study at Memorial Hermann
University of Texas Health Science Center at Houston

The first COVID-19 patient in Texas has been enrolled in a stem cell therapy clinical trial for acute respiratory distress syndrome (ARDS) at The University of Texas Health Science Center at Houston (UTHealth).

Released: 16-Apr-2020 4:20 PM EDT
Need surgery? Here’s why regional anesthesia is safer than general anesthesia during the coronavirus pandemic
American Society of Regional Anesthesia and Pain Medicine (ASRA)

If you don’t have COVID-19, you probably want to stay as far away from a hospital as possible right now. However, the fact is that some people still need emergency surgery. If you or a loved one are in this situation – for any reason – you should know that experts say regional anesthesia may be better than general anesthesia to keep everyone in the operating room safe.asr

Released: 16-Apr-2020 3:50 PM EDT
Indoor precautions essential to stem airborne COVID-19
Queensland University of Technology

World-leading air quality and health expert QUT Professor Lidia Morawska and Professor Junji Cao from Chinese Academy of Sciences in an article in Environment International published this week called on health bodies to initiate research into the airborne transmission of COVID-19 as it is happening

   
Released: 16-Apr-2020 3:00 PM EDT
Mount Sinai Study Finds COVID-19 May Be Driven by Pulmonary Thrombi and Pulmonary Endothelial Dysfunction
Mount Sinai Health System

A new study from the Icahn School of Medicine at Mount Sinai suggests that blood clots, especially in the lungs, may play a role in severe cases of COVID-19.

Released: 16-Apr-2020 11:00 AM EDT
Research News Tip Sheet: Story Ideas From Johns Hopkins
Johns Hopkins Medicine

During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every Tuesday throughout the duration of the outbreak.

Released: 15-Apr-2020 8:00 AM EDT
ECMO Physicians Offer Guidance in the Context of Resource-scarce COVID-19 Treatment
American Thoracic Society (ATS)

Rapidly escalating numbers of COVID-19 patients suffering from respiratory failure threaten to overwhelm hospital capacity and force healthcare providers into making challenging decisions about the care they provide. Of particular interest is the role of ECMO – extracorporeal membrane oxygenation, a form of life support for patients with advanced lung disease – to support critically ill patients in the current pandemic.

Released: 14-Apr-2020 4:05 PM EDT
Smoking Increases Risk for COVID-19 Complications—So It’s a Great Time to Quit
The Society of Thoracic Surgeons

It is well known that smoking results in worse outcomes in people with pneumonia or influenza, and we are learning that smoking can pose significant risks in those with COVID-19.

Released: 14-Apr-2020 11:30 AM EDT
When you can't cough ― extra COVID-19 precautions for people with physical disabilities
Mayo Clinic

People with conditions such as spinal cord injury, Lou Gehrig's disease and multiple sclerosis are at risk of developing severe respiratory problems related to COVID-19 because the muscles that help them breathe already may not function normally.

Released: 14-Apr-2020 8:50 AM EDT
Study finds remdesivir effective against a key enzyme of coronavirus that causes COVID-19
University of Alberta

Scientists at the University of Alberta have shown that the drug remdesivir is highly effective in stopping the replication mechanism of the coronavirus that causes COVID-19, according to new research published today in the Journal of Biological Chemistry.

   
Released: 14-Apr-2020 8:00 AM EDT
LABA/LAMA Combination Therapy More Effective for COPD Patients with Exercise Intolerance
American Thoracic Society (ATS)

Clinicians grappling with the pharmacologic management of COPD in patients complaining of exercise intolerance or dyspnea now have new guidance. The American Thoracic Society has published an official clinical practice guideline in which a panel of experts strongly recommended LABA/LAMA combination therapy over LABA or LAMA alone. The complete guideline detailing all the recommendations was posted online ahead of print in the American Journal of Respiratory and Critical Care Medicine.

Released: 13-Apr-2020 2:05 PM EDT
Is It Allergies or COVID-19?
Loyola Medicine

Spring allergies are in full force. So how do you know if your symptoms are due to allergies or the COVID-19 virus? In a new video, “How allergy symptoms differ from COVID-19,” Loyola Medicine allergist Rachna Shah, MD, outlines the different symptoms for each, and why it's important to keep your spring allergy and asthma symptoms under control during this pandemic.



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