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Stem Cells

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Medicine

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Lymphoma, DHL, Stem Cell Transplant, Stem Cell Transplantation, Chemotherapy

Stem-Cell Transplants Show Limited Benefit for Double-Hit Lymphoma Patients in Remission

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Patients with double hit lymphoma (DHL) who undergo autologous stem-cell transplantation (autoSCT) after achieving remission are not more likely to remain in remission or live longer than patients who do not undergo autoSCT, according to a new analysis from the Perelman School of Medicine and the Abramson Cancer Center of the University of Pennsylvania.

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New Lung “Organoids” in a Dish Mimic Features of Full-Size Lung

New lung “organoids”—tiny 3-D structures that mimic features of a full-sized lung—have been created from human pluripotent stem cells by researchers at Columbia University Medical Center (CUMC). The team used the organoids to generate models of human lung diseases in a lab dish, which could be used to advance our understanding of a variety of respiratory diseases.

Medicine

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T Cell, Stem Cell, Cancer, Lung Cancer, Cancer Vaccine

Stem Cell Vaccine Found to Increase Immune Responses, Inhibit Tumors in Animal Models

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Researchers at the University of Cincinnati (UC) have found that a cancer stem cell vaccine, engineered to express a pro-inflammatory protein called interleukin-15 (IL-15) and its receptor (IL-15Ralpha), caused T cell production in animal models and enhanced immune responses against tumors.

Medicine

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Leukemia, Lymphoma, multiple myelmoma

Twenty-Year Cancer Survivor Gives Back by Donating 20 Handmade Quilts

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Twenty years after undergoing a life-saving treatment at Loyola University Medical Center, cancer survivor Carolyn Gatenby returned to Loyola to donate 20 handmade quilts. “I wanted to give back,” Mrs. Gatenby said. “I’ve had 20 good years that I didn’t think I’d have.”

Science

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Stem Cells, Bone Marrow Cell Therapy, engineered bone, biomimetic bone, Bone Marrow Transplant

Engineered Bone Marrow Could Make Transplants Safer

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Engineers at the University of California San Diego have developed biomimetic bone tissues that could one day provide new bone marrow for patients needing transplants.

Medicine

Science

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Cancer, Metastases, Metastasis, Stage 1-4, Cancer Staging, Biology, Health, Science, San Diego, stem

At Last, a Clue to Where Cancer Metastases Are Born

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Scientists at The Scripps Research Institute (TSRI) have discovered why some cancers may reoccur after years in remission.

Medicine

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Stem Cells, Inner Ear, Inner Ear Balance Disorders, Ear And Hearing, Organoids

Researchers Create Human Inner Ear Organs That Could Lead To New Therapies For Hearing, Balance Impairments

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Researchers at Indiana University School of Medicine have successfully developed a method to grow inner ear tissue from human stem cells—a finding that could lead to new platforms to model disease and new therapies for the treatment of hearing and balance disorders.

Medicine

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Retinal Diseases, Stem Cells, retinal progenitor cells, FDA, Regenerative Medicine Advanced Therapy, Cirm, clinical trial, Blindness, Retinitis Pigmentosa

jCyte Receives Regenerative Medicine Advanced Therapy Designation

Cell therapy company jCyte has received Regenerative Medicine Advanced Therapy designation from the FDA for their developmental retinitis pigmentosa therapy.

Medicine

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Ovarian Cancer, Female Cancer, Gynecologic Cancer, gynecologic cancer research, Cancer Treatment, Combination Therapy, Tumors, ovarian cancer research, Stem Cell

Combination Therapy Could Provide New Treatment Option for Ovarian Cancer

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UCLA study identifies a potential test that may help select patients for whom combination therapy could be most effective

Medicine

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Bipolar Disorder, Manic Depressive Illness, Stem Cell, psychiatric conditions, Mental Health

Auto Pioneer’s Family Helps U-M Turn Tragedy Into Discovery with Promise to Match Donations Up to $5M

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A new $5 million challenge gift aims to boost scientific research on bipolar disorder, while honoring the legacy of an automotive pioneer who battled the condition during his life.







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