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TSRI Researchers Discover How the Brain Turns Chronic Stress into Pathological Anxiety

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In a new study, researchers at The Scripps Research Institute (TSRI) have described how two important molecules in the brain work together to trigger intense anxiety.

Science

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Post Traumatic Stress Disorder, Post Traumatic Stress, FKBP5 gene, FKBP5, fear extinction, Trauma, trauma exposure, Dexamethasone, "fight or flight", Fight-or-Flight reaction, Cortisol

Gene That Helps Form Trauma-Related Memories May Also Help Prevent Post-Traumatic Stress Disorder

A specific gene that helps form memories from traumatic events can be manipulated – and in doing so may actually help prevent post-traumatic stress disorder (PTSD), according to a new study led NYU Langone Medical Center.

Science

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Brain Injury, traumatic brain injury (TBI), Blast Traumatic Brain Injury, Brain Tissue, Neurons, rapid cavitation bubble collapse, Cavitation, neuron fragmentation, Jonathan B. Estrada, Mark Scimone, Harry C. Cramer, Lauren Mancia, Eric Johnsen, Christian Franck, Brown University, University Of Michigan, Office Of Naval Research

Bridging the Gap Between the Mechanics of Blast Traumatic Brian Injuries and Cell Damage

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Traumatic brain injury (TBI) is a largely silent epidemic that affects roughly two million people each year, according to the U.S. Centers for Disease Control and Prevention. But the scale at which blast TBI (bTBI) injuries -- in the spotlight as the signature wound of the wars in Iraq and Afghanistan -- occur and manifest is unknown. Recent studies within this realm suggest that rapid cavitation bubble collapse may be a potential mechanism for studying bTBI, and during the Biophysical Society’s meeting, Feb. 11-15, 2017, Jonathan Estrada will present his work exploring the mechanics of cavitation-induced injury -- with a goal of better understanding bTBIs.

Medicine

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Neurology, Neurology and Neurosurgery, Henry Ford Hospital

Henry Ford Health System Names New Chair of Neurology Department

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World renowned neuro-intensivist and researcher Stephan Mayer, M.D., F.C.C.M., has joined Henry Ford Health System as the new chair of neurology.

Medicine

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Huntington's Disease, Neuro-degenerative disease, Alzheimer's Disease, Parkinson's Disease

Cellular Quality Control Process Could Be Huntington’s Disease Drug Target

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The loss of motor function and mental acuity associated with Huntington’s disease might be treatable by restoring a cellular quality control process, which Duke Health researchers have identified as a key factor in the degenerative illness.

Medicine

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Alzheimers disease, Neurosciences, Neurology, Leon Thal, Howard Feldman

Leon Thal’s Enduring Leadership in AD Research

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A remembrance of Leon Thal, MD, an early giant of Alzheimer’s disease research and treatment by Howard Feldman, MDCM, current director of the Alzheimer’s Disease Cooperative Study at UC San Diego School of Medicine.

Medicine

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stimulated Raman scattering microscopy, Brain Tumor, Brain Surgery, Neurosurgery

New Imaging Technique Automates Analysis of Brain Tumor Tissue During Surgery

Brain surgery for removing cancerous tissue is a delicate and high-stakes task. Now researchers funded by NIBIB have created a way to improve tumor removal surgery by distinguishing cancerous tissue from healthy tissue faster. The method developed by researchers at the University of Michigan Medical School makes brain tumor surgery more precise, improving safety.

Medicine

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Hospice, Depression, Aniexty, Caregiver

Caregivers Should Be Screened Early, Often to Prevent Depression, Anxiety

Currently, more than 34 million people in the U.S. care for terminally ill love ones, but few resources are available to help them navigate the challenges they encounter. A study at the University of Missouri School of Medicine found that nearly one-quarter of caregivers were moderately or severely depressed and nearly one-third had moderate or severe anxiety. The researchers recommend that health providers remember to treat the whole family, providing ongoing screening to family caregivers to identify early signs of depression and anxiety.

Medicine

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Muscular Dystrophy, Genetics, Rare Diseases, Pediatrics, Pediatricians, Congenital Muscular Dystrophy, Intellectual Disability, Muscle Weakness, Short Stature, Cataracts, Genetic Mutation, The George Washington University, GW School of Medicine and Health Sciences, Dystroglycanopathies, Marinesco-Sjögren syndrome, Reproductive And Developmental Health, Mu

GW Researcher Finds Genetic Cause of New Type of Muscular Dystrophy

George Washington University & St. George's University of London research, published in The American Journal of Human Genetics, outlines a newly discovered genetic mutation associated with short stature, muscle weakness, intellectual disability, and cataracts, leading researchers to believe this is a new type of congenital muscular dystrophy.

Medicine

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Brain Damage Is Not Always Damaging

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Strokes are usually, but not always, debilitating. This case report documents the extraordinary resilience of a woman in Argentina who endured multiple strokes.

Medicine

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Physiology, Concussion, sports-related concussion, Sports-Related Head Injury, Traumatic Brain Injury, TBI, Cardiovascular System, Autonomic Nervous System, Heart Rate, Blood Pressure

Sports-Related Concussion Negatively Affects Heart Rate, Blood Pressure

A new study finds that concussion causes short-term impairment of the cardiovascular system but that these cardiovascular symptoms typically resolve within three days of the injury.

Medicine

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myelin diseases, Tuberous sclerosis complex, Autism, Epilepsy, Neurobiology

Researchers Identify New Cause of Brain Defects in Tuberous Sclerosis Complex

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Boston Children’s Hospital researchers have uncovered a new molecular pathway that inhibits the myelination of neurons in the brains of patients with the rare genetic disorder tuberous sclerosis complex (TSC). The study, “Neuronal CTGF/CCN2 negatively regulates myelination in a mouse model of tuberous sclerosis complex,” which will be published online February 9 in The Journal of Experimental Medicine, suggests new ways to treat some of the neurological symptoms associated with TSC, including autism and epilepsy.

Medicine

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Headache, Migraine, Cluster Headache, headache medicine, Headache Clinic

Renowned Neurologist to Oversee Headache and Migraine Care and Research at NYU Langone

In a concerted effort to help address the unique and complex needs of patients with headaches and migraines, NYU Langone has recruited nationally renowned expert Lawrence Newman, MD, to serve as its new director of the division of Headache Medicine division and as professor (clinical) in the Department of Neurology, where he will lead research and clinical efforts to combat these conditions that can drastically affect a patient’s quality of life.

Medicine

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Miller-Dieker Syndrome , Organoids

Human Brain ‘Organoids’ Offer New Insight Into Rare Developmental Disease

Research led by scientists at UC San Francisco and Case Western Reserve University School of Medicine has used brain “organoids” — tiny 3D models of human organs that scientists grow in a dish to study disease — to identify root causes of Miller-Dieker Syndrome (MDS), a rare genetic disorder that causes fatal brain malformations

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Blood Test May Help Differentiate Parkinson’s From Similar Diseases

A simple blood test may be as accurate as a spinal fluid test when trying to determine whether symptoms are caused by Parkinson’s disease or another atypical parkinsonism disorder, according to a new study published in the February 8, 2017, online issue of Neurology®, the medical journal of the American Academy of Neurology.

Medicine

Science

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Neuroscience, Prosthetics, Neuroprosthetics, Vision, Blindness, Neurology

UChicago Receives $2.4 Million NIH Grant to Build Visual Prosthesis

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The University of Chicago Medicine has been awarded a $2.4 million, five-year grant from the National Institutes of Health (NIH) to develop a system of wireless brain implants that might restore partial vision to people who have lost their sight.

Medicine

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PTSD Symptoms May Be Prevented With Ketamine

Columbia University researchers have evidence that giving a small dose of ketamine one week before a psychologically traumatic event may help prevent PTSD. The study, in mice, may have implications for soldiers who are at risk for trauma and PTSD.

Science

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Brain Function, touch research, fMRI, Synesthesia, Somatosensory, Somatosensory Cortex, psychological and brain sciences, Brain Science

Researchers Find That Some Feel an Invisible Touch

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University of Delaware researchers have found two out of 100 people have a condition called mirror-touch synesthesia (MTS) in which they feel like they’re being touched while watching someone else get touched. The team plans to use an fMRI to better understand brain function in those with MTS.

Medicine

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schizophenia, Glutamate, kynurenine, Mental Health, Neuroscience

Researchers Find Chemical Switch That May Decrease Crucial Symptoms of Schizophrenia

A new study by University of Maryland School of Medicine researchers has found that in mice, adjusting levels of a compound called kynurenic acid can have significant effects on schizophrenia-like behavior. The study appeared in the latest issue of the journal Biological Psychiatry.

Medicine

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Organoids, Miller-Dieker Syndrome , Brain Development, Lissencephaly, Stem Cells

Human Brain ‘Organoids’ Offer New Insight into Rare Developmental Disease

Research led by scientists at UC San Francisco and Case Western Reserve University School of Medicine has used brain “organoids” — tiny 3D models of human organs that scientists grow in a dish to study disease — to identify root causes of Miller-Dieker Syndrome (MDS), a rare genetic disorder that causes fatal brain malformations.







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