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  • Embargo expired:
    19-Apr-2018 2:00 PM EDT

Article ID: 693015

Defect in Debilitating Neurodegenerative Disease Reversed in Mouse Nerves

Washington University in St. Louis

Scientists have developed a new drug compound that shows promise as a future treatment for Charcot-Marie-Tooth disease, an inherited, often painful neurodegenerative condition that affects nerves in the hands, arms, feet and legs. The researchers used the compound to treat the nerves of mice harboring the genetic defects that cause the disease.

Released:
17-Apr-2018 5:05 PM EDT
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  • Embargo expired:
    19-Apr-2018 12:00 PM EDT

Article ID: 692866

Human Protein Important for Cellular Communication Resembles Bacterial Toxin

University of Chicago Medical Center

A protein that plays an important role in embryonic development and nervous system wiring in humans appears to have been borrowed from bacteria. In a new study, scientists from the UChicago and Stanford describe the three-dimensional structure of proteins called teneurins for the first time.

Released:
16-Apr-2018 10:05 AM EDT
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  • Embargo expired:
    19-Apr-2018 12:00 PM EDT

Article ID: 692896

Scientists Identify Connection Between Dopamine And Behavior Related To Pain And Fear

University of Maryland School of Medicine

Scientists have for the first time found direct causal links between the neurotransmitter dopamine and avoidance – behavior related to pain and fear. Researchers have long known that dopamine plays a key role in driving behavior related to pleasurable goals, such as food, sex and social interaction. In general, increasing dopamine boosts the drive toward these stimuli. But dopamine’s role in allowing organisms to avoid negative events has remained mysterious.

Released:
16-Apr-2018 1:00 PM EDT
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Embargo will expire:
24-Apr-2018 9:00 AM EDT
Released to reporters:
19-Apr-2018 9:05 AM EDT

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 24-Apr-2018 9:00 AM EDT

  • Embargo expired:
    18-Apr-2018 4:00 PM EDT

Article ID: 692848

Preliminary Study Suggests Drug May Help Babies with Spinal Muscular Atrophy

American Academy of Neurology (AAN)

A preliminary study suggests that an investigational drug may help increase protein levels in babies with spinal muscular atrophy. The open-label study is released today and will be presented at the American Academy of Neurology’s 70th Annual Meeting in Los Angeles, April 21 to 27, 2018.

Released:
15-Apr-2018 11:05 PM EDT
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  • Embargo expired:
    18-Apr-2018 4:00 PM EDT

Article ID: 692846

A Single Concussion May Increase Risk of Parkinson’s Disease

American Academy of Neurology (AAN)

People who have been diagnosed with a mild concussion, or mild traumatic brain injury, may have a 56 percent increased risk of developing Parkinson’s disease, according to a study published in the April 18, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology.

Released:
15-Apr-2018 10:05 PM EDT
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Article ID: 693101

Leptin’s Neural Circuit Identified

Tufts University

Scientists identified a neural circuit in the hypothalamus as the primary mechanism mediating the hormone leptin’s anti-obesity and anti-diabetes effects and found two mechanisms underlying leptin’s inhibition of appetite. The work in mice advances efforts to treat human obesity and diabetes.

Released:
18-Apr-2018 3:05 PM EDT
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  • Embargo expired:
    18-Apr-2018 2:00 PM EDT

Article ID: 692845

Difference in Gene Switching Discovered in Different Parts of Brain

Virginia Tech

Virginia Tech researcher Chang Lu and his team found significant difference in the molecular machinery that turns on and off gene expression between cerebellum and prefrontal cortex of a mouse brain. Their results provide clues to the molecular apparatus that is involved in conscious thinking in brains.

Released:
15-Apr-2018 2:00 PM EDT
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  • Embargo expired:
    18-Apr-2018 12:00 PM EDT

Article ID: 692227

Making Sense of Senses: Researchers Find the Brain Processes Sight and Sound in the Same Two-Step Manner

Georgetown University Medical Center

Although sight is a much different sense than sound, Georgetown University Medical Center neuroscientists have found that the human brain learns to make sense of these stimuli in the same way.

Released:
12-Apr-2018 11:00 AM EDT
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  • Embargo expired:
    18-Apr-2018 12:00 PM EDT

Article ID: 692929

Brain Scans May Help Diagnose Neurological, Psychiatric Disorders

Washington University in St. Louis

A new study shows that individual brain networks are remarkably stable from day to day and while undertaking different tasks, suggesting that finding differences between individuals could help diagnose brain disorders or diseases.

Released:
16-Apr-2018 4:05 PM EDT
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