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  • Embargo expired:
    19-Apr-2018 2:00 PM EDT

Article ID: 693113

New Imaging Method Identifies How Normal and Cancer Cells Move and Adapt

Stony Brook University

An international team of scientists have developed a new cell imaging technology combining lattice light sheet microscopy (LLSM) and adaptive optics (AO) to create high-resolution “movies” of cells in their 3D environment that also captures subcellular processes

Released:
18-Apr-2018 5:05 PM EDT
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Article ID: 693064

Five Johns Hopkins Scientists Among 83 Who Will Share in $15 Million Award From Chan Zuckerberg Initiative to Fund Computer-Based Research on Human Cells

Johns Hopkins Medicine

Five Johns Hopkins scientists, with specialties spanning computation, genetics, statistics and engineering, are among 83 others from 53 institutions in the U.S and eight other countries, who will share in a $15 million award from the Chan Zuckerberg Initiative.

Released:
19-Apr-2018 1:00 PM EDT
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Article ID: 693166

Johns Hopkins Gene Hunter Elected to the American Academy of Arts and Sciences

Johns Hopkins Medicine

Johns Hopkins scientist Steven Salzberg, Ph.D., known for his ability to tackle the most difficult projects in genome sequencing, has been elected as a member of the American Academy of Arts and Sciences. He joins the group of 213 scientists, scholars, writers, artists and other leaders, including former President Barack Obama and Supreme Court Justice Sonia Sotomayor, who make up the class of 2018.

Released:
19-Apr-2018 12:30 PM EDT
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  • Embargo expired:
    19-Apr-2018 10:00 AM EDT

Article ID: 693065

Gene Editing on a Chip: Researchers Use CRISPR to Edit DNA Outside of the Cell for the First Time

Christiana Care Health System

Scientists at Christiana Care Health System’s Gene Editing Institute have developed a potentially breakthrough CRISPR gene-editing tool. It could allow researchers to take fragments of DNA extracted from human cells, put them into a test tube, and quickly and precisely engineer multiple changes to the genetic code, according to a new study published today in the CRISPR Journal.

Released:
19-Apr-2018 10:00 AM EDT
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Article ID: 693097

How Environmental Pollutants and Genetics Work Together in Rheumatoid Arthritis

Michigan Medicine - University of Michigan

New research documents how chemicals and a certain gene activate an enzyme to increase the risk and severity of RA and bone destruction.

Released:
19-Apr-2018 8:00 AM EDT
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  • Embargo expired:
    18-Apr-2018 5:00 PM EDT

Article ID: 693120

Pioneering Gene Therapy by UCSF Benioff Children’s Hospital Oakland Researchers Demonstrates Therapy Can Eliminate Life-Long Need for Transfusions in Patients with Incurable Blood Disorder

UCSF Benioff Children's Hospital Oakland

Interim results of clinical trials by investigators at UCSF Benioff Children’s Hospital Oakland and Ann and Robert H. Lurie Children’s Hospital of Chicago reveal that a majority of the 22 patients in two Phase 1/2 studies followed for two years or longer remained free from transfusions. The results of the trials “Gene Therapy in Patients with Transfusion-Dependentβ-Thalassemia,” are published today in the New England Journal of Medicine (NEJM). The results are from two separate, two-year clinical studies using LentiGlobin® gene therapy to stop or reduce chronic blood transfusions in patients with transfusion-dependent β-thalassemia (TDT).

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18-Apr-2018 6:05 PM EDT
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Article ID: 693101

Leptin’s Neural Circuit Identified

Tufts University

Scientists identified a neural circuit in the hypothalamus as the primary mechanism mediating the hormone leptin’s anti-obesity and anti-diabetes effects and found two mechanisms underlying leptin’s inhibition of appetite. The work in mice advances efforts to treat human obesity and diabetes.

Released:
18-Apr-2018 3:05 PM EDT
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  • Embargo expired:
    18-Apr-2018 2:00 PM EDT

Article ID: 692845

Difference in Gene Switching Discovered in Different Parts of Brain

Virginia Tech

Virginia Tech researcher Chang Lu and his team found significant difference in the molecular machinery that turns on and off gene expression between cerebellum and prefrontal cortex of a mouse brain. Their results provide clues to the molecular apparatus that is involved in conscious thinking in brains.

Released:
15-Apr-2018 2:00 PM EDT
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Article ID: 692974

Direct Electrical Current Used to Preferentially Inhibit Pain-Transmitting Neurons

Johns Hopkins Medicine

Using computer models and laboratory rats, Johns Hopkins researchers have demonstrated that “direct electrical current” can be delivered to nerves preferentially, blocking pain signals while leaving other sensations undisturbed.

Released:
18-Apr-2018 8:00 AM EDT
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Article ID: 693022

UNMC, Genomoncology Combine to Launch First System Using HL7 2.5 Formatting to Transmit Discrete Genetic Data on Cancer Patients to Electronic Health Record

University of Nebraska Medical Center (UNMC)

Breakthrough streamlines patient information into a manageable, digestible format, so oncologists can view discrete genetic data in the patient 's electronic health record

Released:
18-Apr-2018 4:00 AM EDT
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