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Medicine

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B cell leukemia

Penn Study Links Mutations in Notch Gene to Role in B Cell Cancers

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Researchers found that in B cell tumors, mutated overactive versions of the Notch protein directly drive the expression of the Myc gene and many other genes that participate in B cell signaling pathways. Myc is a critical gene in governing cell proliferation and survival.

Medicine

Science

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flu, Influenza, Epidemiology, Public Health, Infectious Disease

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 25-Oct-2017 2:00 PM EDT

Medicine

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disorder of sex development, Intersex

How Hospitals Respond When It’s Uncertain if the Newborn Is a Boy or a Girl

When babies are born with atypical sex anatomy, how a hospital responds has a major impact on a family’s experience and decisions about sometimes irreversible procedures.

Science

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Neutrino, Neutrinos, neutrinoless double beta decay, Berkeley, Lawrence Berkeley National Laboratory, LBNL, Berkeley Lab, CUORE, INFN, Italy, double beta decay

Experiment Provides Deeper Look into the Nature of Neutrinos

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The first glimpse of data from the full array of a deeply chilled particle detector operating beneath a mountain in Italy sets the most precise limits yet on where scientists might find a theorized process to help explain why there is more matter than antimatter in the universe.

Medicine

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Type 1 Diabetes, Teen Health, Financial Incentives, Behavioral Economics, Adolescent Health, Penn Medicine, Children's Hospital Of Philadelphia, JAMA Pediatrics, Diabetes Management

Are Teens More Likely to Take Charge of Their Health when Money is on the Line?

A new study shows that using small financial incentives and accessible monitoring tools such as wireless glucometers and apps may motivate young people to engage in playing a more active role in the management of their condition. The results show that participants in the intervention group, where a $60 monthly credit was on the line, were nearly three times more likely to achieve daily glucose monitoring goals. The authors say the study, published today in JAMA Pediatrics, shows that the strategy may be an effective way to reach a population that has historically been considered difficult to engage.

Science

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nematic, active nematic, toroid, toroidal droplets, Microtubules

Wriggling Microtubules Help Understand Coupling of “Active” Defects and Curvature

Imagine a tiny donut-shaped droplet, covered with wriggling worms. The worms are packed so tightly together that they locally line up, forming a nematic liquid crystal similar to those found in flat panel displays. In the journal Nature Physics, scientists are reporting on an examination of such an active nematic – but with flexible filaments and microscopic engines rather than worms.

Medicine

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Hydrogel, Organoids, human intestinal organoids, Crohn's Disease, Matrix, Extracellular Matrix

Synthetic Hydrogels Deliver Cells to Repair Intestinal Injuries

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By combining engineered polymeric materials known as hydrogels with complex intestinal tissue known as organoids – made from human pluripotent stem cells – researchers have taken an important step toward creating a new technology for controlling the growth of these organoids and using them for treating wounds in the gut that can be caused by disorders such as inflammatory bowel disease (IBD).

Medicine

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alzheimer disease, Biomarker, Amyloid, Seniors, Neurology, Brain

So My Brain Amyloid Level is “Elevated”—What Does That Mean?

Penn Medicine study illuminates how seniors cope with Alzheimer’s-risk biomarker results

Science

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University of Vienna, Austrian Academy of Science, Magma Oceans, Exoplanets, Nature Astronomy, Space Research, Induction Heating

Formation of Magma Oceans on Exoplanets

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Induction heating can completely change the energy budget of an exoplanet and even melt its interior. In a study published by Nature Astronomy an international team led by the Space Research Institute of the Austrian Academy of Sciences with participation of the University of Vienna explains how magma oceans can form under the surface of exoplanets as a result of induction heating.

Medicine

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Adderall, ADHD, Substance Abuse, Drug Abuse, NYU, CDUHR, NYU Meyers College of Nursing, Palamar, Nyu Langone, Amphetamine

Adolescents Underreport Amphetamine Use, Likely Unaware That Adderall is Amphetamine

Over a Quarter of Teens Taking Adderall On Their Own Do Not Report Taking Amphetamine







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