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Medicine

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severe aplastic anemia, blood and marrow transplant, immune suppression therapy, Pediatric Blood and Marrow Transplantation Consortium

CHLA Awarded $1.3 Million by NIH for Pediatric Blood and Marrow Transplantation Consortium

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The grant provides support for an innovative clinical trial that seeks to compare outcomes for young patients with newly diagnosed severe aplastic anemia – comparing the use of unrelated-donor blood and marrow transplant to immune suppression therapy.

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Human Genetics Studies Reveal New Targets to Reduce Heart Disease

Again and again, it’s the rare among humans that help the rest of us. The exploration of human genetics is revealing new targets to combat heart disease among atypical variants. Mutations in genes that play a role in heart health are the inspiration for a cluster of new heart drugs.

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cardiovascuar disease, Heart Attack, Infarct, Inflammation, Immune Response, Cardiac Remodeling Reversing Heart Failure, Congestive Heart Failure, Lipoxin, Macrophage, Neutrophil

A Bioactive Molecule May Protect Against Congestive Heart Failure After Heart Attacks

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A form of the fatty acid-derived bioactive molecule called lipoxin improved heart function after a heart attack, as the lipoxin prompted early activation of the resolving phase of the immune response in mice without altering the acute phase.

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Synthetic Version of Popular Anticoagulant Poised for Clinical Trials

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A synthetic version of low molecular weight heparin is poised for clinical trials and development as a drug for patients with clotting disorders, and those undergoing procedures such as kidney dialysis, heart bypass surgery, stent implantation, and knee and hip replacement.

Medicine

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Ted Rogers Centre for Heart Research, cardiac genomics, Heart Failure, Genomics, Medical Genetics, University Health Network

New Medical Geneticists Join Ted Rogers Centre for Heart Research

The Ted Rogers Centre for Heart Research today announces that Dr. Raymond Kim is its newest scientific lead, guiding efforts at the country’s only clinic devoted to cardiac genomics.

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Assessment Tools, Relationships Key to Addressing Child Trauma

Two new studies led by researchers at the Johns Hopkins Bloomberg School of Public Health suggest that the bevy of tools available to assess and address childhood adversity and trauma, as well as the interconnected webs of relationships among families and the providers who care for children, are key to healing the effects of these potentially life-altering circumstances.

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Science

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Heart Hormones Protection, Psychotic Disorders, Self Regulation, and More in the Obesity News Source

Click here to go directly to Newswise's Obesity News Source

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Science

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X-Ray Footprinting, Brain Development, Sleep Research, and More in the Cell Biology News Source

The latest research and features in cell biology in the Cell Biology News Source

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Diabetes, Heart Disease, genes

Diabetes and Heart Disease Linked by Genes, Reveals Penn-led Study

Type 2 diabetes (T2D) has become a global epidemic affecting more than 380 million people worldwide; yet there are knowledge gaps in understanding the etiology of type-2 diabetes. T2D is also a significant risk factor for coronary heart disease (CHD), but the biological pathways that explain the connection have remained somewhat murky. Now, in a large analysis of genetic data, published on August 28, 2017 in Nature Genetics, a team, led by researchers in the Perelman School of Medicine at the University of Pennsylvania, has first looked into what causes T2D and second clarified how T2D and CHD – the two diseases that are the leading cause of global morbidity and mortality, are linked.

Medicine

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Cardio, Cardiology, Cardiology and Heart Surgery, LVAD, LVADs, Trial, Study, FDA, FDA Approval, Heart, Heart Failure

Leading LVAD Expert Available to Discuss FDA Approval of Newer LVAD Device, HeartMate3







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