Dirty air now could harm hearts of offspring later
Ohio State UniversityA parent’s exposure to dirty air before conception might spell heart trouble for the next generation, a new animal study suggests.
A parent’s exposure to dirty air before conception might spell heart trouble for the next generation, a new animal study suggests.
AIDS patients suffer higher rates of cancer because they have fewer T-cells in their bodies to fight disease. But new research examines why HIV-infected patients have higher rates of cancer—among the leading causes of death among that population—than the general population.
Cleveland Clinic medical oncologist and researcher, Alok Khorana, M.D., is the primary investigator on a study that concluded rivaroxaban for venous thromboembolism (VTE), a blood clot in the venous system, significantly reduced VTE and VTE-related death for outpatient, at-risk cancer patients while they were taking the oral blood thinner. During the on-treatment period, blood clots occurred less frequently (2.62 percent) in patients taking rivaroxaban, compared to and 6.41 percent of the placebo groups. However, during the full study period – which included 180-day observation after the medication was stopped ¬– the gap narrowed with blood clots occurring in 5.95 percent of patients in the rivaroxaban group, compared to 8.79 percent of the placebo groups.
Real-world learning experiences, like summer camps, can significantly improve children’s knowledge in a matter of just days, a new study suggests.
After over a decade of preclinical research and development, a new gene therapy treatment for Sickle Cell Anemia (SCA) is reversing disease symptoms in two adults and showing early potential for transportability to resource-challenged parts of the world where SCA is most common.
A new approach co-developed at The Ohio State University uses data analytics and machine learning to predict the conservation status of more than 150,000 plants worldwide. Results suggest that more than 15,000 species likely qualify as near-threatened, vulnerable, endangered or critically endangered.
A few months ago, Protective Services officers at Cincinnati Children's requested help from our Marketing & Communications team on a video. They wanted to be part of a lip sync challenge.
CINCINNATI--A gene mutation that is believed to have safeguarded some people in 14th century Europe from the bubonic plague today may be protecting HIV patients co-infected with hepatitis C from potentially fatal liver scarring, says a University of Cincinnati (UC) College of Medicine physician-scientist.
When deciding whether to participate in programs designed to conserve energy during peak hours, consumers appear to rely more on their intuition about how much money they’re saving rather than on proof their bills are smaller, a new study has found.
A daily hydroxyurea pill may bring relief for children living with the painful and deadly blood disease sickle cell anemia (SCA) in resource-challenged sub-Saharan Africa, where the disease is prevalent and health care is suboptimal. This is what a multinational clinical trial called REACH discovered when it tested daily hydroxyurea treatment in 606 children between the ages of 1 and 10 years old. Study data are published in the New England Journal of Medicine.
In a recent issue of the Proceedings of the National Academy of Sciences, Lin Mei, MD, PhD, asked, does all the tinkering in young mice hamper their brain development, causing schizophrenia-like symptoms? Or, do their brain cells develop normally, but in adulthood struggle to communicate? Researchers need to know whether to focus their efforts on brain cell development or communication, or both, because the answer to these questions implies different therapeutic approaches.
A team of researchers led by Jonathan Stamler, MD, of Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center, has discovered a pathway for enhancing the self-repair efforts of injured kidneys. The finding may pave the way for new drugs to stop or even reverse the progression of serious kidney disease in humans—and other potentially lethal conditions of the heart, liver, and brain as well.
A new study from The Ohio State University found that mailing at-home HPV tests to hard-to-reach women may be a viable approach, one that could be especially helpful in regions such as Appalachia, where access to women’s health care can be limited.
A breakthrough study published in Nature Communications has demonstrated, in animal models of chronic injury, that long-term, devastating effects of spinal cord trauma on breathing and limb function may be reversible. The new study describes a treatment regimen that helps reawaken certain special types of nerve cells that can regenerate extensions, called axons, within the damaged spinal cord.
Sometimes, there is no “tragedy” in the tragedy of the commons, according to a new analysis that challenges a widely accepted theory. In an analysis of eight case studies from around the world, researchers found that people can successfully share and sustainably use resources, under certain conditions.
Many experts agree the future of flight will rely on zero-emission and/or renewable energy technology. That is, aircraft will be propelled by ions—electrically charged molecules—that create thrust in their wake. But that future is already here.
Electronic health records (EHRs) produce savings for hospitals by reducing the average length of patient stays—but only in facilities meeting the highest federal standards for implementing the technology
A planet discovered by a team co-led by Ohio State University astronomers spent this week crushing other planets in an international, intergalactic competition known as the ExoCup.
Twelve pieces of ancient mosaics in Bowling Green State University’s art collection are being packed for their return to the Republic of Turkey.
People who vape and smoke cigarettes are no more likely to drop the nicotine habit than those who just smoke, a new study suggests. Researchers at The Ohio State University studied 617 tobacco users and found no differences in quit rates for “dual users” of both traditional and electronic cigarettes.
Bowling Green State University doctoral biology student Audrey Maran was chosen for the highly competitive John A. Knauss Marine Policy Fellowship. She will serve for a year as a communication specialist in the National Sea Grant office, a division of the National Oceanic and Atmospheric Administration.
A Cleveland Clinic genetic analysis has found that obesity itself, not just the adverse health effects associated with it, significantly increases the risk of Type 2 diabetes and coronary artery disease. The paper was published today in the Journal of the American Medical Association Network Open.
It is an idea for repairing our broken political system that is so promising that new members of Congress will learn about it before taking office in January. It is an idea tested with actual representatives and their constituents, with intriguing and positive results.
A new national study shows that people whose mothers had more partners – married or cohabiting – often follow the same path.Results suggest that mothers may pass on personality traits and relationship skills that make their children more or less likely to form stable relationships.
The brains of teenage girls who engage in serious forms of self-harm, including cutting, show features similar to those seen in adults with borderline personality disorder, a severe and hard-to-treat mental illness, a new study has found.
Rong Xu, PhD, recently received a total of $5 million for two projects that will use big data methods for a comprehensive look at a range of factors that may inform the mechanism of Alzheimer’s and related dementia.
A nurse’s ability to provide optimal patient care is influenced by a variety of factors – not just how many patients he or she is caring for or how sick they might be, a new study suggests.
Genetic testing revealed Robin Gramke and her daughter McKenna have a complex condition called 22q.
Researchers from Case Western Reserve University School of Medicine have shown that a single “cocktail” of three pill-based anti-parasite medications is significantly more effective at killing microscopic larval worms in people diagnosed with lymphatic filariasis, commonly known as elephantiasis, than other standard two-drug combinations previously used in the global effort to eliminate this infectious disease. A combination of all three drugs given simultaneously had never been tested until now. An estimated 120 million people in over 50 tropical and subtropical countries are infected with lymphatic filariasis and another 856 million people are at risk.
Leading cancer researcher, Alex Huang MD, PhD, has been awarded a three-year, $1.35 million grant from the St. Baldrick’s Foundation and the Osteosarcoma Collaborative to develop new ways to treat osteosarcoma, a rare cancer that begins in the bone.
By eliminating one type of immune cell in the brain, researchers were able to erase any evidence of inflammation following traumatic brain injury, according to a new study from The Ohio State University.
n experimental drug is showing some promise in stopping mood abnormalities and cognitive disorders similar to those seen in people with Gulf War illness, an animal study suggests.
Case Western Reserve University School of Medicine and partners have been awarded a five-year, $6M grant from the Paris-based Fondation Leducq to conduct a thorough analysis of the pivotal role of KLF2 in vascular-related functions and disorders. The team’s grant was one of five awarded globally and aims to improve knowledge and treatment of cardiovascular disease.
The immune system might play an important role in the development of postpartum depression after a stressful pregnancy, new research suggests.
Case Western Reserve University School of Medicine is preparing and inspiring a new generation of cancer investigators through Cancer-focused Summer Undergraduate Research (CanSUR). The 10-week program recently received a five-year National Institutes of Health (National Cancer Institute) research grant totaling $1.6 million. Starting in 2019, CanSUR will support 32 undergraduates each year from June through August.
New research could help explain why stress early in life can create vulnerabilities to mood and anxiety disorders later on. The study, led by researchers at The Ohio State University, was presented Nov. 5 in San Diego at the annual Society for Neuroscience meeting, and highlights the important role of mast cells.
To help reduce the effects of TBIs in youth sports, all 50 states and the District of Columbia enacted state youth TBI laws between 2009 and 2014. A new study from researchers in the Center for Injury Research and Policy at Nationwide Children’s Hospital examined the effectiveness of these laws by looking at sports and recreation mild TBI (mTBI)-related emergency department (ED) visits for children ages 5 to 18 years before and after TBI legislation was enacted in each state.
The trick to boosting crops in drought-prone, food-insecure areas of West Africa could be a ubiquitous native shrub that persists in the toughest of growing conditions. Growing these shrubs side-by-side with the food crop millet increased millet production by more than 900 percent.
Ascena tween retailer Justice is supporting Nationwide Children’s Hospital this Holiday season with its “Believe in Magic, Believe in Justice” campaign running November 1 through January 5, 2019.
Serotonin (3A) receptors are common drug targets in the treatment of pain, gastrointestinal dysfunctions, and mood disorders yet little is known about their three-dimensional structure. Details about serotonin receptor structures could provide important clues to designing better drugs with less side effects. Now, a team of researchers from Case Western Reserve University School of Medicine have used high-powered microscopes to view serotonin activating its receptor for the first time. Images published in Nature reveal molecular details about the receptor that could improve drug design to treat a multitude of diseases.
Taking a look at the perpetrators of domestic violence
University Hospitals has opened a food market in one of its health clinics which is located in one of Ohio's most food insecure counties. Food for Life Market will address food insecurity and chronic illnesses, such as high blood pressure, through free healthy, fresh foods, combined with physician visits.
A single protein regulates a battery of key genes inside developing sperm, according to a new study out of Case Western Reserve University School of Medicine. Scientists discovered the protein—called Dazl—controls a network of genes essential for developing sperm to replicate and survive. The findings, published in Cell Reports, could lay the groundwork for future research into therapies for infertile men.
Announcement of Dr. Peter Pronovost joining University Hospitals health system in Cleveland, Ohio as its Chief Clinical Transformation Officer.
Cincinnati Children’s Hospital Medical Center, seed investor CincyTech announced the formation and seed financing of Clarigent Health, a platform technology company leveraging artificial intelligence and natural language processing to give health care providers a new clinical decision support tool to address suicide, which in recent years has risen at alarming rates among teens.
In the races for U.S. Senator and the governorship in Ohio, there has been little movement among undecided voters. In all three polls, Democratic incumbent Senator Brown had at least a 15-point lead over Republican Congressman Renacci. In the most recent poll, Brown leads Renacci, by about 20 points, with 17% of respondents indicating they are unsure how they will vote.