A unique wearable artificial vision device may help people who are legally blind “read” and recognize faces. It may also help these individuals accomplish everyday tasks with significantly greater ease than using traditional assistive reading devices, suggests a study presented today at AAO 2016, the 120th annual meeting of the American Academy of Ophthalmology.
Whether you see the gossamer wings of a butterfly or the delicate opened petals of a flower, there is beauty in the eye of the beholder — a mouse retina described and visually captured by scientists at the National Center for Microscopy and Imaging Research (NCMIR) at University of California San Diego School of Medicine and Shiley Eye Institute at UC San Diego Health.
People who closely follow the Mediterranean diet – especially by eating fruit – may be more than a third less likely to develop age-related macular degeneration, a leading cause of blindness, according to a study presented today at AAO 2016, the 120th annual meeting of the American Academy of Ophthalmology. The study is the first to identify that caffeine may be especially protective against AMD.
The American Academy of Ophthalmology today announced key milestones in its ongoing effort to use the power of data science to improve medical and surgical eye care. In less than three years since its introduction, the Academy’s IRIS® (Intelligent Research in Sight) Registry is now the world’s largest clinical database. Academy leaders discussed the most recent milestones with the effort during several events at AAO 2016, the Academy’s 120th Annual Meeting.
Mount Sinai researchers are using optimal coherence tomography (OCT) angiography to look at the earliest stages of glaucoma and identify characteristic patterns of different forms of glaucoma based on their vascular patterns. The research can help lead to earlier diagnosis and slow down progression of vision loss.
The visual cortex – a region of the brain known to process sensory information – plays a key role in promoting the plasticity of innate, spontaneous eye movements, according to a study funded by the National Eye Institute (NEI), part of the National Institutes of Health.
Ophthalmologists at Massachusetts Eye and Ear are currently accepting patients who may be candidates for a newly FDA-approved outpatient procedure known as “corneal cross-linking.” Corneal cross-linking is a stabilizing treatment to halt the progression of keratoconus, a degenerative eye condition in which the cornea becomes thin and irregularly shaped. Keratoconus can affect adults and children as young as preteenagers, and may result in progressive vision loss if left untreated. While eyeglasses and contacts can serve as visual aids for these patients, —with advanced cases sometimes requiring corneal transplant surgery — corneal cross-linking is currently the only treatment available that can stop the progression of keratoconus.
Chicago will become the global epicenter of the latest discoveries in ophthalmology this week as thousands of eye physicians and surgeons attend AAO 2016, the American Academy of Ophthalmology’s 120th annual meeting. The world's largest showcase for vision research and innovation will be held in conjunction with the Asia-Pacific Academy of Ophthalmology on Oct. 14-18 at McCormick Place.
A new study sought to improve diabetic eye health by examining the barriers to retinal screening and found patients and health care providers had markedly divergent perceptions of the barriers.
Researchers at Vanderbilt University Medical Center and Vanderbilt University have received a $1.9 million grant from the National Institutes of Health (NIH) to support research to restore vision through regeneration of the retina.
The National Eye Institute has awarded UAB’s Jason Nichols and colleagues a $1.9 million grant for dry eye research that could lead to a targeted therapy.
Migrant farmworkers have substantial rates of near- and distant-vision problems, but three-fourths have never had a vision screening test, reports a study in the October issue of Optometry and Vision Science, official journal of the American Academy of Optometry. The journal is published by Wolters Kluwer.
The call for abstracts opens Friday, Sept. 30, for the second annual Optimal Aging Conference, hosted by the Univeristy of Louisville Institute for Sustainable Health & Optimal Aging and the Kentucky Association for Gerontology. The conference will be held June 11-13, 2017.
In cases of severe ocular trauma involving the cornea, wound healing occurs following intervention, but at the cost of opaque scar tissue formation and damaged vision. Recent research has shown that mesenchymal stem cells (MSCs) — which can differentiate into a variety of cells, including bone, cartilage, muscle, and fat cells — are capable of returning clarity to scarred corneas; however, the mechanisms by which this happens remained a mystery – until now. In a study published online today in Stem Cell Reports, researchers from Schepens Eye Research Institute of Massachusetts Eye and Ear have identified hepatocyte growth factor (HGF), secreted by MSCs, as the key factor responsible for promoting wound healing and reducing inflammation in preclinical models of corneal injury. Their findings suggest that HGF-based treatments may be effective in restoring vision in patients with severely scarred corneas.
Researchers from the U.S. and India have begun a new collaborative project to identify genetic risk factors and traits related to glaucoma, a leading cause of blindness worldwide. Funded by the National Eye Institute (NEI), part of the National Institutes of Health (NIH), and India’s Department of Biotechnology (DBT), the researchers’ goal is to help develop effective screening, prevention, and treatment strategies for glaucoma. Grants from the two agencies stem from a bilateral initiative, the U.S.-India Collaborative Vision Research Program, designed to advance knowledge in the biological mechanisms of ocular disease.
A common pathway involved in photoreceptor death has been identified in retinitis pigmentosa, advanced dry age-related macular degeneration and other retinal diseases, with early evidence of a possible halt to vision loss related to treatment of the pathway.
As many as half of people are blind to motion in some part of their field of vision, but the deficit doesn’t have anything to do with the eyes. In a new study, University of Wisconsin–Madison psychology Professor Bas Rokers and collaborators in the Netherlands have shown that motion blindness is a failure of the brain to properly interpret sensory information — a type of deficit called agnosia.
"Vision impairment remains notably absent from many population health agendas and community programs,” say the authors of a new report, "Making Eye Health a Population Health Imperative: Vision for Tomorrow," from The National Academies of Sciences, Engineering, and Medicine.
A $1.9 million grant to Indiana University from the National Institutes of Health's National Eye Institute will advance basic research on the eye with applications to blindness caused by genetic disorders and aging.
Complications of diabetes can lead to blindness, yet only 29.9 percent of diabetic patients studied adhered to recommendations to have an eye examination.
Neuroscientists at University of California, Irvine have discovered a molecular signaling mechanism that translates visual impairments into functional changes in brain circuit connections. The discovery may help to develop novel therapeutic drugs to treat the childhood visual disorder amblyopia and other neurodevelopment disorders
Researchers at Massachusetts Eye and Ear have discovered a new mutation in a highly antibiotic-resistant strain of E. coli that resists clearance by the body’s own immune system by inhibiting white blood cells that ordinarily kill and remove bacteria. In a paper published online today in JAMA Ophthalmology, the researchers describe the case that led them to discover the mutation, and offer suggestions for how to recognize and address this particular microbe if encountered in the future.
The BrightFocus Foundation has awarded a glaucoma research grant of more than $149,000 to J. Crawford Downs, Ph.D., of the University of Alabama at Birmingham, for his work on a new wireless system to measure and control fluid pressure around the optic nerve.
Researchers from Massachusetts Eye and Ear have, for the first time, identified rapidly proliferating cells (known as “neural crest-derived progenitor cells”) in the corneal endothelium of specimens from normal corneas and from corneas with Fuchs’ Endothelial Corneal Dystrophy (FECD), a condition in which the cells responsible for keeping the cornea clear die prematurely — often leading to blindness. The findings, published in the American Journal of Pathology, hold promise for new therapies to be developed using the proliferating cells to return normal clearing abilities to the cornea in patients with FECD.
Lonza Houston, Inc., a global leader in viral gene and cell therapy manufacturing, and Massachusetts Eye and Ear, the world’s largest vision and hearing research center, have entered into a strategic agreement that provides customers the ability to in-license Anc80 and other Anc-AAVs for the clinical development and commercialization of novel gene therapies. The agreement is designed to accelerate gene therapy drug development across the field in order to address diseases in need of treatments and thereby ultimately reach more patients.
Patients suffering from noninfectious uveitis, a group of diseases that causes eye inflammation, can get effective treatment from a corticosteroid alternative that has previously been approved for treatment of arthritis and Crohn’s disease, according to a study led by a Duke Health researcher.
Researchers at Washington University School of Medicine in St. Louis published a study that shows that genetic material from the Zika virus has been found in tears. The study, fast-tracked for publication in Cell Reports, was conducted in mice, thereby creating an animal model for studying transmission and treatment of this alarming virus. The study, published September 6, 2016, also confirms that the Zika virus can lead to cell death in the eyes. Research to Prevent Blindness, located in New York, provided funding for this study.
Researchers at McMaster University have re-invented the eye drop with technology that can deliver medicine much more efficiently, making life easier for patients.
The National Institutes of Health will fund six projects to identify biological factors that affect neural regeneration in the retina. The projects are part of the National Eye Institute (NEI) Audacious Goals Initiative (AGI), a targeted effort to restore vision by regenerating neurons and their connections in the eye and visual system. These projects will receive a total of $12.4 million over three years, pending availability of funds.
Tall quarterbacks might have more going for them than a clear view over the offensive line. New research shows that tall people are better than shorter people at correctly identifying the location of targets in their middle-distance vision – between three and 20 meters away. (In football, that would be about three to 22 yards away.)
For people with nearsightedness (myopia), the lens doesn't compensate for growth or other changes in the structure of the eye, according to a long-term follow-up study in the September issue of Optometry and Vision Science, official journal of the American Academy of Optometry. The journal is published by Wolters Kluwer.
A contact lens designed to deliver medication gradually to the eye could improve outcomes for patients with conditions requiring treatment with eye drops, which are often imprecise and difficult to self-administer. In a study published online today in Ophthalmology, a team of researchers have shown that a novel contact lens-based system, which uses a strategically placed drug polymer film to deliver medication gradually to the eye, is at least as effective, and possibly more so, as daily latanoprost eye drops in a pre-clinical model for glaucoma.
Interfering with your vision makes it harder to describe what you know about the appearance of even common objects, according to researchers at the University of Wisconsin–Madison.
The $1.4 million, two-pronged initiative involves funding partnerships with Lions Clubs International Foundation (LCIF), Reader’s Digest Partners for Sight Foundation (RDPFS), and our newest partner, Consumer Technology Association™ Foundation (CTAF).
With back-to-school time around the corner, parents will be scrambling to buy new school supplies and clothes. As they tick off their long list of school to-dos, ophthalmologists are reminding moms and dads not to neglect one of the most important learning tools: their children’s eyes.
A new study in animal models, led by scientists at The Scripps Research Institute (TSRI), suggests that the eye's lacrimal glands can be repaired by injecting a kind of regenerative “progenitor” cell.
Researchers from the Schepens Eye Research Institute of Massachusetts Eye and Ear have identified new underlying mechanisms of proptosis, or bulging of the eyes, in patients with acute thyroid eye disease. In a report published online in the journal Ophthalmology, the researchers describe vascular growth factors causing an abnormal proliferation of blood vessels, as well as the rare formation of lymphatic vessels, that may contribute to the dangerous swelling and inflammation that occurs in the orbits of these patients. The findings point to new potential targets for non-surgical therapies to decompress the eye in the acute phase of thyroid eye disease.
Children with crossed eyes are less likely to get the help they need if they live in poor communities. It's cause for concern because strabismus can lead to permanent vision loss.
Can your child read what's on the chalkboard? Or see the teacher from the back of the room? "Glasses may be the most important back-to-school supply many children get this year," said Eileen Gable, OD, an eye specialist at Loyola Medicine. "Vision problems in young children often go undetected and are difficult for family members to identify."
San Francisco, CA, August 16, 2016 - Because of the beneficial effect of corticosteroids on lung function, especially in infants who are ventilator dependent, corticosteroids are, at times, administered to very low birth weight neonates to treat established or evolving lung disease. However, it has long been suspected that steroids may have negative neurodevelopmental effects on very premature infants. In a study in the Journal of the American Association for Pediatric Ophthalmology and Strabismus (AAPOS), researchers found that for very premature infants with birth weights of less than 500 grams, there was a 1.6 times increased risk for retinopathy of prematurity (ROP) and a 1.7 times greater chance for advanced ROP.
Scientists have found a variation of the miR-182 gene in patients with primary open-angle glaucoma that results in this overexpression, said Dr. Yutao Liu, vision scientist and human geneticist in the Department of Cellular Biology and Anatomy at the Medical College of Georgia at Augusta University.
One- and two-year-old children are at the highest risk of burning their eyes with chemicals, despite the long held belief that working-age adults were the most at risk from this type of severe eye injury, new Johns Hopkins Bloomberg School of Public Health-led research suggests.
Combinations of Food and Drug Administration-approved drugs protect against the loss of cells required for vision in a mouse model of the damage caused by blinding retinal diseases.
Do you have dry eyes or other symptoms related to wearing contact lenses? If so you're not alone—up to 50 percent of contact lens wearers experience dryness or discomfort at least occasionally. New research aimed at understanding and managing this common and complex problem is presented in the special August issue of Optometry and Vision Science, official journal of the American Academy of Optometry. The journal is published by Wolters Kluwer.