Feature Channels: Vaccines

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WHO ignores significant data, including several large clinical trials, while claiming insufficient evidence to recommend the use of ivermectin to prevent and treat COVID-19

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Houston Methodist infectious disease pathologists have discovered new COVID-19 cases caused by the SARS-CoV-2 UK B.1.1.7 variant are doubling weekly. By mid-March the number increased sharply to 648 cases from 305 just a week earlier. The findings come from the latest batch of 8,857 virus genomes sequenced from patients with positive COVID-19 tests in the first two months of 2021, representing 94% of Houston Methodist cases.

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More and more Americans are becoming vaccinated against COVID-19, but headlines warn that the number of cases is rising. What’s up with that?

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FAU's Joanna Drowos, D.O., M.P.H., M.B.A., provides answers to some of the most frequently asked questions regarding COVID-19 vaccines.

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An article launched today by the Forum of International Respiratory Societies (FIRS), an organization comprised of the world's leading international respiratory societies, including the American Thoracic Society, highlights COVID-19 efficacy and safety and calls for urgent equitable access in all countries.

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More than a quarter of all U.S. parents say they do not intend to vaccinate their children against COVID-19, according to preliminary results from a study by Indiana University researchers.

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During the 2020-2021 fall semester, school districts around the United States navigated their reopening plans with little data on how SARS-CoV-2 spreads among children or how in-person learning would impact transmission in the schools’ communities. A new study in The Journal of School Health joins a growing body of evidence that, with appropriate measures, there are ways for schools to safely reopen.

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February 18, 2021 – King Chulalongkorn Memorial Hospital, The Thai Red Cross Society, Chula Faculty of Medicine, and Chula Vaccine Research Center (Chula VRC) jointly held a press conference on “The latest development on ChulaCov19 vaccine and its readiness for clinical trial”. On the panel were H.E. Anutin Charnvirakul, Deputy Prime Minister and Public Health Minister; Dr. Nakorn Premsri, the Director of National Vaccine Institute (NVI); Prof.Dr. Suttipong Wacharasindhu, Director of King Chulalongkorn Memorial Hospital, The Thai Red Cross Society and Dean of Chula Faculty of Medicine; and Dr.Kiat Ruxrungtham, Director of Chula Vaccine Research Center (Chula VRC). The event was moderated by Assoc. Prof. Dr. Jiruth Sriratanaban, Deputy Director of King Chulalongkorn Memorial Hospital.

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Researchers will study vaccinated and non-vaccinated health workers who get tested for the virus after experiencing common COVID-19 symptoms like fever, cough or a loss of sense of taste or smell. They will compare the incidence of positive tests and severity of illness in those who test positive.

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The foremost network of cancer centers in the United States is recommending that people wait to get certain imaging such as mammograms until four to six weeks after their final dose of their coronavirus vaccine — as long as the delay does not interfere with their health care.

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An international team of researchers led by a University of Virginia School of Medicine professor is warning that scientists must better prepare for the next pandemic – and has developed a plan to do just that.

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Influenza vaccines need to be evaluated every year to ensure they remain effective against new influenza viruses.

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A team of UTEP faculty, staff and students observed several of El Paso’s drive-though and walk-in clinics in early 2021. The team identified areas that likely created bottlenecks, which produce delays and other issues. They used the information from their observations to develop simulation models to experiment with a clinic’s performance to further identify potential slowdowns, calculate resource utilization and reduce patient waiting time.

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A new CoVPN study evaluating SARS-CoV-2 infection and transmission among college students vaccinated with the Moderna COVID-19 vaccine was announced today. The new trial will tell us whether a person can become infected after they’ve been vaccinated and if the vaccine will stop the virus from spreading person-to-person.

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Although demand for COVID-19 vaccines currently seems high, vaccine hesitancy could pose a major threat to public health efforts to end the pandemic, according to an editorial published today in the journal Science.

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As millions of people pack airports and planes over spring break at a time when only 25 percent of the population has received at least one COVID-19 vaccination, Lewis Nelson, director of the Department of Emergency Medicine at Rutgers New Jersey Medical School, says public health measures while traveling like social distancing, washing hands and mask wearing are still critical to remaining healthy and stopping the spread.

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Irvine, Calif., March 24, 2021 – Vaccines are here, but as COVID-19 cases continue and variants spread, researchers need easy access to a wide variety of data to better understand the disease. Led by the University of California, Irvine, UC hospitals have received a $500,000 grant from the National Institutes of Health to make this possible.

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Researchers at the Pritzker School of Molecular Engineering at the University of Chicago have developed a new therapeutic vaccine that uses a patient’s own tumor cells to train their immune system to find and kill cancer.

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One year ago, then 65-year-old Miriam Clark developed a fever, lost her appetite and had no energy. She and her daughter, Tye Clark, the administrative services manager of the Johns Hopkins University School of Medicine Division of Hospital Medicine, never could have imagined what they would end up going through before Miriam was diagnosed with COVID-19. Looking back on the year, the mother and daughter duo are thankful and now even have reason to celebrate.

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Ahead of the first U.S. emergency use authorization for a COVID-19 vaccine, only half of Americans said they were likely to get vaccinated as soon as possible.

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As COVID-19 vaccines slowly roll out across the world, government officials in densely populated countries must still manage vulnerable communities at highest risk of an outbreak. In a new study published in the journal Risk Analysis, researchers in India propose a COVID Risk Assessment and Mapping (CRAM) framework that results in a zoned map that officials can use to place more targeted restrictions on high-risk communities. Successfully used by officials in Jaipur at the peak of the pandemic last spring, their framework could help other vulnerable countries avoid a shutdown of their regional economies.

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A COVID-19 vaccine that could provide protection against both existing and future strains of the COVID-19 virus, and other coronaviruses, and cost about $1 a dose has shown promising results in early animal testing.

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People who received a flu shot last flu season were significantly less likely to test positive for a COVID-19 infection when the pandemic hit, according to a new study. And those who did test positive for COVID-19 had fewer complications if they received their flu shot.

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The Foundation for Opioid Response Efforts (FORE) and the Addiction Policy Forum (APF) are launching a program to assist people with substance use disorder obtain COVID-19 vaccinations.

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Wistar is pleased to announce the appointment of Richard M. Horowitz as chair of its Board of Trustees.

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Incorporating Black churches and clergy in COVID-19 vaccination education and distribution has been found to be an effective model in helping to increase vaccination delivery to historically at-risk populations in San Bernardino County, a study says.

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Fluid mechanics-based transport modeling in the human respiratory tract and research data were used to determine which droplet sizes are most like to reach the dominant infection site and the number of virus particles needed to trigger infection.

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DALLAS – March 23, 2021 – Vaccinating health care workers resulted in an immediate and notable reduction of positive COVID-19 cases among employees, reducing the number of required isolations and quarantines by more than 90 percent, according to data at UT Southwestern Medical Center published in the New England Journal of Medicine.

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Investigators from UC San Diego and UCLA report COVID-19 infection rates for a cohort of health care workers previously vaccinated for the novel coronavirus. Risk of infection is minuscule, but exists.

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The vaccinator workforce is an essential component of the COVID-19 response and recovery. However, since administration of the two FDA-authorized COVID-19 vaccines began in December 2020, the rollout has encountered several challenges and failed to meet initial targets for total vaccinations provided. The current health workforce has been identified as one possible bottleneck for distributing the vaccine, prompting a general call to authorize as many healthcare professionals to administer the vaccine as possible. To track this fast-moving issue at the state level, researchers at the Fitzhugh Mullan Institute for Health Workforce Equity have created an interactive tool that displays temporary, emergency state policies authorizing specific professions to provide the COVID-19 vaccine.

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接受第二剂信使RNA或mRNA COVID-19疫苗10天后，与未接种COVID-19疫苗的患者相比，无症状COVID-19感染者检测为阳性和在不知不觉中传播COVID-19的可能性大幅降低。Pfizer-BioNTech和Moderna信使RNA COVID-19疫苗已在美国获得紧急使用授权。

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Dez dias após receber uma segunda dose de uma vacina para COVID-19 de RNA mensageiro, ou mRNA, pacientes sem sintomas de COVID-19 têm muito menos probabilidade de apresentar teste positivo e espalhar COVID-19 inadvertidamente, em comparação com pacientes que não foram vacinados para COVID-19.

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Public participation is critical to the success of medical research. Yet recruiting volunteers for trials is increasingly challenging. New Washington University research suggests the widening ideological gap in the U.S. may be to blame.

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More than 50 scientific experts from across the United States, including virologists, infectious disease specialists and medical doctors, are launching a series of virtual town halls today to answer the public’s questions about the COVID-19 vaccines.

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Most people with cancer who are infected by the novel coronavirus produce antibodies at a rate comparable to the rest of the population—but their ability to do so depends on their type of cancer and the treatments they’ve received, according to a new study by researchers at Montefiore Health System and Albert Einstein College of Medicine. The findings, published online today in Nature Cancer, may lead to better care for cancer patients, who face a heightened risk of dying from COVID-19, and suggests that cancer patients should respond well to COVID-19 vaccines.

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On Feb. 22, the University of California San Diego brought together a panel of industry experts and esteemed faculty to kick off the university’s “Evenings of Nonconventional Wisdom” online event series hosted in celebration of the university's 60th anniversary. To continue the timely dialogue around COVID-19 and vaccines, we reached back out to a few of the event panelists plus a leader from UC San Diego’s Return to Learn Program Dr. Robert “Chip” Schooley to answer questions submitted by the audience.

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A new report shows parents are more vaccine hesitant and resistant than non-parents (in terms of willingness to vaccinate themselves) across all socioeconomic and demographic groups compared. This pattern is largely driven by younger mothers, who are far more vaccine resistant than younger women who are not mothers. Older parents and fathers show little difference from their non-parent peers.

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The study will involve more than 2,000 residents, staff, and visitors of long-term care homes in Ontario over the course of a year. Blood and saliva will be examined.

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The proof-of-concept AMP studies demonstrated that a broadly neutralizing antibody (bnAb) called VRC01 was effective at preventing the acquisition of HIV strains to the 30% of strains that were sensitive to the bnAb. This finding was seen both in Sub-Saharan Africa and the U.S. and South America. VRCO1 did not prevent the acquisition of HIV to strains that were resistant to the bNAb.

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This is a landmark study in so far as being the first to raise the alarm that, despite early successes with Covid-19 vaccines, further research is warranted on a next generation of Covid-19 vaccines.

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With topics ranging from the food we eat, the air we breathe, and the land we dwell on to the health of our body and mind, and the well-being of all things in the universe, this is a program that is for everyone and anyone. So, stay tuned and listen LIVE on Chula Radio Plus

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Research reveals how mutated SARS-CoV-2 evades immune system defenses In lab-dish experiments, the mutant virus escaped antibodies from the plasma of COVID-19 survivors as well as pharmaceutical-grade antibodies Mutations arose in an immunocompromised patient with chronic SARS-CoV-2 infection Patient-derived virus harbored structural changes now seen cropping up independently in samples across the globe Findings underscore the need for better genomic surveillance to keep track of emerging variants Results highlight importance of therapies aimed at multiple targets on SARS-CoV-2 to minimize risk of resistance