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Genetics

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Medicine

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eye, Cancer, Genetics, Testing, Counseling, Metastasis, risk, Ocular, Melanoma

Cancer Patients Want Genetic Testing to Predict Metastasis Risk; Results Have Little Effect on Mood, Quality of Life

If you had cancer and a genetic test could predict the risk of aggressive metastasis, would you want to know "“ even if no treatments existed to help you? An overwhelming majority of eye cancer patients would answer yes, according to a new UCLA study published in the June edition of the Journal of Genetic Counseling.

Medicine

Channels:

ASCO, Genetics, Testing, Brca1, Brca2, Breast, Cancer, New, Jersey

Most Parents Share Genetic Testing Results with Offspring

New research shows that most parents who undergo genetic testing to assess their risk of breast cancer in particular, tell their young children of the results. The study, presented at the annual American Society of Clinical Oncology meeting, also looks at how parents perceive their child's reaction to such news.

Medicine

Channels:

Aeg 1, Neuroblastoma

Researchers Identify Gene That Regulates Tumors in Neuroblastoma

Virginia Commonwealth University researchers have identified a gene that may play a key role in regulating tumor progression in neuroblastoma, a form of cancer usually found in young children. Scientists hope the finding could lead to an effective therapy to inhibit the expression of this gene.

Medicine

Channels:

Testicular Cancer, Cancer Genes, Cancer Genetics, Genetic Risk Factors, Genome, Genome Wide Association Study

Researchers Discover Genetic Risk Factor for Testicular Cancer

Researchers at the University of Pennsylvania School of Medicine have uncovered variation around two genes that are associated with an increased risk of testicular cancer. Testicular cancer is the most common cancer among young men, and its incidence among non-Hispanic Caucasian men has doubled in the last 40 years -- it now affects seven out of 100,000 white men in the United States each year.

Medicine

Channels:

Primary Biliary Cirrhosis, Liver

Researchers Discover Genetic Cause for Primary Biliary Cirrhosis

Researchers have discovered a novel molecular path that predisposes patients to develop primary biliary cirrhosis, a disease that mainly affects women and slowly destroys their livers. Primary biliary cirrhosis has no known cause.

Science

Channels:

Genetics, Proteins, Dietary Restriction, Cancer, Aging

Identification of Key Protein May Explain Anti-cancer, Anti-aging Benefits of Dietary Restriction

A protein that plays a key role in tumor formation, oxygen metabolism and inflammation is involved in a pathway that extends lifespan by dietary restriction. The finding provides a new understanding of how dietary restriction contributes to longevity and cancer prevention and gives scientists new targets for developing and testing drugs that could extend the healthy years of life.

Medicine

Channels:

Genetics, Transplant, Genetics, Cyclosporine A, Blood Pressure, Anti Rejection, Renal, Kidney, American Society Of Nephrology, ASN

Gene Test Determines Transplant Drug Tolerance

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A simple genetic test can determine a kidney transplant patient's tolerance for a potent anti-rejection medication, according to an upcoming study in the Journal of the American Society Nephrology (JASN). The test could allow doctors to individualize each patient's dose, optimizing the drug's benefits and minimizing its side effects.

Medicine

Channels:

Autism, Genetics, DNA, Asperger, Brain, Disorder

Scientists Identify New Gene Linked to Autism Risk, Especially in Boys

UCLA scientists have discovered a variant of a gene that may increase a child's risk of developing autism, particularly in boys.

Life

Law and Public Policy

Channels:

Genetics, Patent, Lawsuit, aclu, Cancer, Myriad

Indiana University Law Professor Available to Discuss ACLU Gene Patent Lawsuit

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The American Civil Liberties Union filed a lawsuit (May 11) against the Patent and Trademark Office, Myriad Genetics, and the University of Utah Research Foundation for patenting two genes associated with hereditary breast and ovarian cancers. Yvonne Cripps, the Harry T. Ice Professor of Law at Indiana University Maurer School of Law, says this is likely to be a landmark case.

Science

Medicine

Channels:

Tumor Suppressor Genes, Ctcf, Parlation, Breast Cancer, Cancer

Good Fences Make Good Neighbors

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Our genome is a patchwork of neighborhoods that couldn't be more different: Some areas are hustling and bustling with gene activity, while others are sparsely populated and in perpetual lock-down. Breaking down just a few of the molecular fences that separate them blurs the lines and leads to the inactivation of at least two tumor suppressor genes, according to researchers at the Salk Institute for Biological Studies.







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