People who ate a diet high in nuts and legumes, low-fat dairy, whole grains, fruits, and vegetables and low in red and processed meat, sugar-sweetened beverages and sodium were at a significantly lower risk of developing chronic kidney disease over the course of more than two decades, new Johns Hopkins Bloomberg School of Public Health research suggests.
The George Washington University Ron & Joy Paul Kidney Center has launched a kidney health education campaign in the Washington, D.C. area, which has the highest prevalence of kidney disease in the U.S. Advertisements encouraging residents to check their kidney health have started to appear on buses, with television, radio and digital media advertisements appearing throughout the next year.
Researchers have successfully tested a new method for the early diagnosis in children and teenagers of diabetic nephropathy, a serious complication of diabetes that can increase risk of death. This new method, unveiled today at the 68th AACC Annual Scientific Meeting & Clinical Lab Expo, would help pediatric patients get necessary treatment in a more timely manner.
U.S. News and World Report’s 2016-2017 “Best Hospitals” guide has recognized eight University of Virginia Health System specialties and ranked UVA as the No. 1 hospital in Virginia.
For the second consecutive year, Rush University Medical Center improved in U.S. News & World Report’s rankings in the annual “Best Hospitals” issue, which became available today. U.S. News ranked Rush among the best hospitals in the country in nine specialty areas – two more than last year – and Rush improved in the rankings for eight of those specialties.
Bolstering its progress in addressing the rising threat of kidney cancer, the Kidney Cancer Program at UT Southwestern Medical Center’s Harold C. Simmons Comprehensive Cancer Center has received $11 million in funding from the National Cancer Institute (NCI). Kidney cancer currently has no method of early detection and is particularly challenging to treat.
A stranger started a chain of events that led to six people receiving new kidneys at one institution.
Early diagnosis of acute kidney injury in preterm infants is possible through urinary protein markers.
• The amounts of protein excreted in the urine of preterm infants with acute kidney injury differ from similar infants without kidney injury.
Five University at Buffalo research projects aim to study how the interplay of the human microbiome – the collection of microorganisms that reside in and on the human body – and the environment affect a person’s risk for certain diseases.
A multicenter team of researchers led by Barbara Murphy, MD, of the Icahn School of Medicine at Mount Sinai has identified a panel of genes which can help predict whether a transplanted kidney will later develop fibrosis, an injury which can cause the organ to fail.
• A metabolite that is normally excreted in urine was linked with impaired cognitive function in patients with kidney failure. • The metabolite has been previously linked to cognitive impairment in other patient populations.
Water supply contamination has become a global issue, affecting communities in both the United States and around the world. Exposure to environmental toxins - such as arsenic, cadmium, chromium, lead and other heavy metals - early in life via contaminated water or other sources can have long-term health consequences as children grow. Investigators at Brigham and Women's Hospital and the Harvard Program in Therapeutic Sciences at Harvard Medical School have assessed environmental exposure to multiple toxins in children living in a region of Mexico with a high incidence of chronic kidney disease, especially among young adults. Not only did the team detect high levels of the arsenic and chromium in urine samples from the children, they also were able to detect elevated levels of KIM-1, a biomarker that is being studied as an early sign of kidney injury. The team's findings are published this week in Environmental Research.
• Red meat intake was strongly associated with an increased risk of kidney failure among Chinese adults in Singapore who were followed for an average of 15.5 years. • No association was found with intakes of poultry, fish, eggs, or dairy products, while soy and legumes appeared to be slightly protective.
• The likelihood of developing membranous nephropathy, an immune disorder of the kidneys that can lead to kidney failure, increased 13% annually over 11 years in China. • Regions with high levels of fine particulate air pollution had the highest rates of membranous nephropathy.
The ASN Foundation for Kidney Research announced the 2016 recipients of research grants to advance new understandings of—and treatments for—kidney diseases. The Foundation will fund 36 leading researchers working to cure kidney diseases. These include new projects and others continuing from 2015. Established in 2012 by the American Society of Nephrology, the Foundation funds research that will help improve the health of the more than 20 million Americans burdened by kidney diseases, the 9th leading cause of death in the United States.
Doctors and scientists at Intermountain Medical Center in Salt Lake City printed and used a 3D kidney to help save a patient's organ during a complicated tumor-removal procedural.
David Killilea, PhD, a staff scientist at Children's Hospital Oakland Research Institute (CHORI), co-authored a study into the causes of kidney stones. The study was conducted by the University of California, San Francisco (UCSF), in collaboration with the Buck Institute for Research on Aging in Marin County and Children's Hospital Oakland Research Institute (CHORI). Published in the prestigious scientific journal PLOS ONE, the study revealed that high levels of zinc in the body may contribute to kidney stone formation.
Using virtual tissue technology, researchers at Indiana University have identified a potential new drug target in the fight against polycystic kidney disease, an illness with no effective FDA-approved treatment that affects 200,000 people per year in the United States. The study, which appears in the journal Molecular Biology of the Cell, reveals that errors in how cells stick together give rise to two forms of kidney cysts.
In a first-of-its-kind procedure in the United States, a patient was able to avoid dialysis when surgeons simultaneously removed two diseased kidneys and also transplanted a kidney from a living donor – all as part of a 28-person paired kidney exchange
A kidney transplantation means much more than good health to Jason E. Jones. The 53 year-old Hyde Park artist and Loyola Medicine patient draws daily creative inspiration from his chronic health experience. "My new kidney changed not only my life but my life's work," said Mr. Jones, who has been an artist for two decades. "My whole health journey became part of my artistic process and my daily experiences with medication and dialysis were incorporated into my artwork."
Highlight • Diabetes and kidney disease, separately and together, were linked with increased risks of stroke, coronary heart disease, and cardiovascular mortality in African Americans living in Mississippi.
Eric Wallace is piloting a telehealth program, which he says could open the door for Alabamians in rural communities to receive more subspecialized care without traveling long distances.
Up to 30 percent of people who receive organ transplants will develop diabetes, but researchers are unsure why. A new study in kidney transplant recipients suggests that patients with more inflammation prior to surgery are more likely to develop diabetes than those with less overall inflammation, and that a patient’s fat stores also play a role.
Researchers find cytoreductive nephrectomy may offer an overall survival benefit to patients with metastatic kidney cancer who are treated with targeted therapies
• Two-thirds of the children with kidney disease were classified as vitamin D deficient. • Children with kidney disease who took vitamin D supplements had vitamin D levels that were 2 times higher than those who did not take supplements. • Certain genetic variants were also associated with vitamin D levels.
Washington, DC (June 16, 2016)—The Journal of the American Society of Nephrology (JASN) retains a very prominent position in the field of nephrology in Impact Factor for 2015, with a score of 8.5 according to Journal Citation Reports® (JCR). This Impact Factors reflects the average annual number of citations in 2015 to articles published in a journal during 2013 and 2014.
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According to data from the large, multinational LEADER clinical trial, the glucose-lowering drug liraglutide safely and effectively decreases the overall risk of heart attack, stroke, or cardiovascular death, kidney disease, and death from all causes for people with type 2 diabetes.
Montefiore Health System has a new collaborative program with its partner St. John’s Riverside Hospital to offer patients suffering from kidney, pancreas or liver disease an opportunity to be evaluated for transplantation at St. John’s Riverside Hospital by specialists from Montefiore Einstein Center for Transplantation.
Washington, DC (June 13, 2016) — The Kidney Health Initiative (KHI) is pleased to support President Barack Obama’s call to action through its attendance at the White House Organ Summit on Monday, June 13. This Summit will examine ways to improve the outcomes for individuals waiting for organ transplants and support living donors in addition to improving kidney patient care options and access to transplantation.
Washington, DC (June 13, 2016) —More than 20 million Americans live with kidney diseases. About 650,000 have end-stage renal disease (ESRD) and need dialysis or a transplant to live. Kidney diseases disproportionately affects minority populations; African Americans, Asian Americans, Hispanics, and Native Americans are four times more likely to develop kidney failure, and African Americans in low income neighborhoods are 57 percent less likely to make the transplant list.
New Living Donor Navigator Program tailored to African-Americans and a new Facebook app aim to increase access to living kidney transplants and reduce the number of patients awaiting transplant.
Absorption and excretion of calcium were faster in certain patients with a history of kidney stones.
Early findings by researchers at the University of Cincinnati (UC) College of Medicine suggest that the use of a second generation cancer drug, carfilzomib, may provide an improved approach for the reduction of antibodies in potential kidney transplant candidates.
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Repeated heat-related dehydration has been associated with increased risk of chronic kidney damage in mice. A new study in rats published in the American Journal of Physiology—Regulatory, Integrative and Comparative Physiology reports that drinking soft drinks to rehydrate worsened dehydration and kidney injury. This study is highlighted as one of this month’s “best of the best” as part of the American Physiological Society’s APSselect program.
Surgeons at the University of Illinois Hospital & Health Sciences System have — for the first time — used an orphan drug to prevent rejection of a kidney transplanted from a living donor with a mismatched blood type.
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• A common genetic variant that is present in approximately 40% of Caucasian individuals was linked with an increased risk of kidney damage after heart surgery. • The variant results in decreased expression of a gene involved in maintaining iron balance in the body.
Researchers at Queen’s University Belfast are to examine DNA samples from 20,000 people with diabetes to help identify the genetic factors in diabetic kidney disease, the leading cause of kidney failure worldwide.
Today three major nephrology societies — the American Society of Nephrology (ASN), the European Renal Association – European Dialysis and Transplant Association (ERA-EDTA), and the International Society of Nephrology (ISN) ― signed a declaration of collaboration. The organizations agreed that kidney disease is a global challenge that respects no boundaries or borders. Therefore, all available synergies should be used to fight kidney disease and improve the standard of care for kidney patients worldwide.
• In patients with chronic kidney disease, those with more advanced disease had higher blood levels of the bacterial metabolite phenylacetylglutamine. • Patients with high phenylacetylglutamine had an elevated risk of developing cardiovascular disease as well as a heightened risk of dying prematurely.
Many young adults with abdominal obesity exhibit a readily detectable risk factor for chronic kidney disease (CKD), yet the vast majority don’t know they’re at risk, according to a study of nationwide health data led by Albert Einstein College of Medicine researchers that was published online today in the journal PLOS ONE.
In a study appearing in the May 24/31 issue of JAMA, Jiang He, M.D., Ph.D., of the Tulane University School of Public Health and Tropical Medicine, New Orleans, and colleagues evaluated more than 3,500 participants with chronic kidney disease (CKD), examining the association between urinary sodium excretion and clinical cardiovascular disease (CVD) events.
Only 12% of kidney cancer patients with advanced disease survive five years after their initial treatment. In a Roswell Park Cancer Institute-led study, scientists report that some patients with advanced kidney cancer who continued to receive a novel immunotherapy drug after their disease progressed saw clinical benefit. The research was published online ahead of print in JAMA Oncology, a journal of the American Medical Association.
• Kidney function remained unchanged among hypertensive adults in communities assigned to a public health intervention for general practitioners and community health workers, whereas kidney function significantly declined among those who received usual care. • Individuals in the communities with the intervention were half as likely as other individuals to experience a >20% decline in kidney function within 5 years after the intervention was stopped.
• In the See Kidney Disease (SeeKD) Targeted Screening program undertaken by the Kidney Foundation of Canada, 89% of patients who were screened reported at least 1 risk factor for chronic kidney disease (CKD), and of those, 19% had unrecognized CKD.
A team of physicians from Christiana Care Health System and computer scientists from the University of Delaware is using merged electronic health records to improve care and clinical outcomes for patients with chronic kidney disease, which affects some 26 million American adults.
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