Feature Channels: Addiction

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Heavy drinking can have a number of negative consequences, including sex that is later regretted. Low sensitivity (LS) to alcohol’s effects – which characterizes the person who can “drink everyone under the table” – is a known risk factor for heavy drinking and its consequences. This study investigated LS and regretted sex from an unusual perspective, asking whether LS could be protective in some contexts, given that LS drinkers are generally less impaired from drinking at a given level. More specifically, the investigators tested whether LS was associated with differences in reports by men and women of alcohol-related regretted sex.

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Summer is in full stride, with people heading to beaches to soak up the sun. But there's more to that behavior than trying to get a good tan, says an epidemiology expert at Indiana University-Purdue University Indianapolis.

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Access to counseling for patients, mentoring for physicians could help increase use, survey says

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Bio-Rad Laboratories, Inc., a global provider of life science research and clinical diagnostic products, announces the launch of recombinant Luteinizing Hormone (LH), which expands the company’s Critical Raw Material offerings.

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A grant from the National Institute on Drug Abuse is funding an innovative, experiential learning program at Northern Arizona University that has successfully trained dozens of students in specialized research methods in the area of adolescent drug abuse.The program is offered through the University of South Florida’s Institute for Translational Research Education in Adolescent Drug Abuse (ITRE).

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A team of researchers has demonstrated that children with autism spectrum disorder have a unique composition of gut bacteria and urinary metabolites compared with unaffected children. The research, revealed today at the 69th AACC Annual Scientific Meeting & Clinical Lab Expo in San Diego, could lead to promising new treatment options for children with autism as well as earlier detection of the disorder.

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Anyone who walked into Monday’s morning symposium, “Novel Psychoactive Substances (NPS) in Emergency Toxicology” thinking that NPS are not a growing threat to public health were quickly disavowed of that notion. Speakers Jennifer Colby, PhD, and Kai Li, MD, described various compounds, including the drug U-47700, which is a synthetic super-opioid that causes extreme euphoria and respiratory depression, frequently leading to adverse effects, including death.

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Researchers have discovered new methods that could improve treatment for infectious diseases by enabling earlier detection of influenza outbreaks and curtailing inappropriate antibiotic usage. The findings were presented today at the 69th AACC Annual Scientific Meeting & Clinical Lab Expo in San Diego.

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Brittany Todd Texas Tech University has named Brittany Todd, associate director of the Office of Student Conduct, as director of the Risk Intervention & Safety Education (RISE) office. She will begin in the new position today (Aug. 1), filling the spot left when Kimberly Simón was named the university’s Title IX administrator in April.

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Researchers have shown that a new genetic test could potentially help stem the tide of the opioid epidemic by predicting which patients are at risk of abusing prescription opioids. These findings were presented for the first time at the 69th AACC Annual Scientific Meeting & Clinical Lab Expo in San Diego.

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A new study shows that a change in policy placing more restrictions on all hydrocodone-containing drugs has successfully decreased the use of certain opioids such as Vicodin. This research and a second study illuminating regional drug use trends in Canada were announced today at the 69th AACC Annual Scientific Meeting in San Diego, and could help to guide future strategies for combatting addiction.

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A new study shows that a change in policy placing more restrictions on all hydrocodone-containing drugs has successfully decreased the use of certain opioids such as Vicodin. This research and a second study illuminating regional drug use trends in Canada were announced today at the 69th AACC Annual Scientific Meeting in San Diego, and could help to guide future strategies for combatting addiction.

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Researchers have shown that a new genetic test could potentially help stem the tide of the opioid epidemic by predicting which patients are at risk of abusing prescription opioids. These findings were presented for the first time at the 69th AACC Annual Scientific Meeting & Clinical Lab Expo in San Diego.

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AACC is pleased to announce the recipients of the AACC 2017 Top Corporate Supporter Awards. This year, AACC recognizes 46 different companies and organizations that generously support the association through sponsorships, advertising, and exhibiting. These significant contributions make it possible for AACC to improve patient care by fostering research, innovation, and professional excellence in the field of laboratory medicine.

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Despite being saddled with many factors associated with drug and alcohol problems, undocumented immigrants are not increasing the prevalence of drug and alcohol crimes and deaths in the United States, according to a new University of Wisconsin-Madison study published in the American Journal of Public Health.

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Ortho Clinical Diagnostics (Ortho), a global leader of in vitro diagnostics, today announced a strategic relationship with B·R·A·H·M·S GmbH, part of Thermo Fisher Scientific Inc., to develop the B·R·A·H·M·S PCT (procalcitonin) assay for use on Ortho’s VITROS® Systems.

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Currier Plastics provides innovative custom molding solutions that create powerful advantages for your business. Our design and engineering expertise combined with the right cost and precise time to market manufacturing provide integrated solutions to improve your business performance.

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BioreclamationIVT, a leading provider of biospecimens and related services, today announced that it has expanded its infectious disease-state portfolio to include frozen whole blood, plasma and serum samples from patients with HIV-1, HIV-2, dengue, zika and malaria infection.

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Diener Precision Pumps, the leading manufacturer of precision piston pumps and gear pumps announces the introduction of a new enhanced Precision Series piston pump at the AACC this year in San Diego.

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Press can register here to livestream this special session through Newswise Live on Monday, July 31 at 7:30 PM EDT

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DWK Life Sciences, having successfully completed the integration of three industry-leading brands into a single, unified international brand, DURAN WHEATON KIMBLE (DWK), is proud to offer the diagnostics industry a convenient, reliable, and complete solution for developing and producing IVD diagnostic kits. Combining our expertise in leak-resistant plastic containers, dropping bottles and closures, diagnostic vials and other innovative packaging solutions with our capabilities in bar coding, particulate cleaning, sterile processing, and an in-house quality control team, DWK Life Sciences offers everything you need to simplify your supply chain for IVD production.

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SCIEX Diagnostics, the in vitro diagnostics division of SCIEX, a global leader in mass spectrometry in the life sciences industry, announced today the first and only FDA-cleared (via the de novo pathway) LC-MS based Vitamin D assay kit, the Vitamin D 200M Assay, exclusively for the SCIEX Topaz™ System

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SCIEX Diagnostics, the in vitro diagnostics division of SCIEX, a global leader in mass spectrometry in the life sciences industry, announced today the launch of the first fully integrated LC-MS system for clinical diagnostics, the SCIEX Topaz™ System.

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At the 69th AACC Annual Scientific Meeting & Clinical Lab Expo—the premier global conference and exhibit for laboratory medicine—visionaries in the field will illuminate the pioneering research and technology paving the way for better clinical testing and patient care. From July 30–August 3 in San Diego, the meeting will feature more than 200 talks on a broad range of timely healthcare topics. Highlights of these include plenaries that explore transforming biology using CRISPR engineering and new applications for DNA sequencing; preserving fertility in young people with cancer; how clinical testing can help solve public health crises; and a session that uncovers the precision diagnostics that are creating a digital health revolution.

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AACC announced today that it will launch a new laboratory medicine conference and expedition next spring – AACC Middle East. AACC Middle East will showcase AACC’s globally-renowned education and scientific programs paired with a dynamic exposition in Abu Dhabi, United Arab Emirates (UAE), March 22-24, 2018.

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At the 69th AACC Annual Scientific Meeting & Clinical Lab Expo—the premier global conference and exhibit for laboratory medicine—visionaries in the field will illuminate the pioneering research and technology paving the way for better clinical testing and patient care. From July 30–August 3 in San Diego, the meeting will feature more than 200 talks on a broad range of timely healthcare topics. Highlights of these include plenaries that explore transforming biology using CRISPR engineering and new applications for DNA sequencing; preserving fertility in young people with cancer; how clinical testing can help solve public health crises; and a session that uncovers the precision diagnostics that are creating a digital health revolution.

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Press can register here to livestream this special session through Newswise Live on Monday, July 31 at 7:30 PM EDT. The winner of the Qualcomm Tricorder XPRIZE competition will present DxtER—a real-life tricorder—at the 69th AACC Annual Scientific Meeting & Clinical Lab Expo in San Diego. This special session will be the first time that the device is presented to researchers at a U.S. scientific conference.

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Drinking alcohol results in an alcohol use disorder (AUD) when consumption becomes excessive and dependence develops. Both stress and anxiety can contribute to the development of an AUD. Chronic stress can increase drinking, and chronic drinking can elevate anxiety and dysregulate normal responses to stressors. Behavioral flexibility and adaptive behavior – essential for controlling excessive drinking – are core functions of the prefrontal cortex (PFC), This study used mice to examine the effects of combined alcohol and stress exposure on PFC function.

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News release from Ortho Clinical Diagnostics regarding CE Mark clearance for VITROS(r) NephroCheck(r)

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The NEFA assay from Wako Diagnostics is designed to detect a variety of non-esterified fatty acids (NEFA). The test is specific to free fatty acids with minimal interferences from other related compounds and serum components such as bilirubin, hemoglobin, and ascorbic acid. The need for an extraction step has been eliminated. The company’s enzymatic method relies upon the acylation of coenzyme A and ultimately results in a purple colored product that can be measured colorimetrically at 550 nm.

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The Autokit CH50 assay from Wako Diagnostics is a fully automated liposome – based assay for the determination of total complement activity in human serum. This proven and widely used methodology can be applied to most automated chemistry analyzers to evaluate deficiency or abnormalities of the complement system. The homogenous size of liposomes gives a stable dispersion. This, along with a fast, 10 minute total reaction time and ease of use makes it the best choice for your lab.

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Ortho news release announcing highest ranking for service

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SynAbs is proud to appoint LuBioSience as its new distributor for Switzerland. LuBioScience has a seasoned team and expertise in selling biochemicals, including the specific monoclonal antibodies of SynAbs, in particular the anti-species which should be welcomed by the Swiss Biopharma R&D and IVD sector.

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RARITAN, N.J. – July 21, 2017 – Ortho Clinical Diagnostics, a global leader of in vitro diagnostics, today announced that Ortho’s VITROS® Immunodiagnostic Products Insulin Reagent and Calibrators have received CE Mark, broadening Ortho’s menu of tests that manage all aspects of diabetes and other pancreatic disorders. An important biomarker in diabetes and pre-diabetes testing, the assay is expected to be commercially available for use on all of Ortho’s VITROS® Immunodiagnostic and Integrated Systems in Europe and other countries accepting the CE Mark during the third quarter of this year. According to the World Health Organization; diabetes affects nine percent of people 18 years or older worldwide.i What’s more, 191 million people with diabetes are currently undiagnosed.ii Diabetes is managed as a chronic, lifelong condition with several significant co-morbidities, so it is vital that laboratories have a partner that supports the continuum of diabetes diagnostics. “Our goal

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Uniflex- Healthcare Packaging, a division of the Uniflex/ S.Walter Packaging company has announced it will be returning to the the AACC 2017 meeting in San Diego, California during July 31-August 3rd, 2017. They will be located at booth 519 at the San Diego Convention Center during the annual meeting. Uniflex has historically been an industry leader and supplier of medical packaging products for 50+ years, and introduced to the market place the liquid-tight adhesive seal specimen bag, the UniVault (R) patient valuables bags, and recently launched its new Lab Shield (R) "Removable-Biohazard" specimen bag. Much excitement surrounds this new product line!

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Monoclonal antibodies development has been limited for a long time to only two species : mice and rats. However, the immune systems of mice and rats are not the most suitable in terms of humoral response to certain antigens, such as human antigens like glucagon. Indeed, the protein sequence of glucagon is the same in mice, rats and human (fig. 1). Small not immunogenic antigens, such as antibiotics or toxins, generally failed to trigger an immune response in such species. This is why some companies have developed fusion cell lines to generate monoclonal antibodies in rabbit (Abcam-Epitomics) or in sheep (Bioventix). However, these two tools are not totally satisfactory whether in terms of cost, stability or productivity.

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News about Ortho Clinical Diagnostics' VITROS(r) Insulin Reagent & Calibrators receiving FDA 510(k) clearance

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The Immunologicals Group of The Binding Site is pleased to announce the launch of a number of new monoclonal antibodies and recombinant antigens focused on a variety of infectious/contagious disease states – including Cytomegalovirus (CMV), Hepatitis, HIV, Rubella, Syphilis, and Toxoplasmosis.

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Dawn Foster, Founder/CEO of Staff Icons, a Global Scientific Recruitment Firm. She brings to the table 25 years of recruiting industry experience. Dawn holds a Bachelor’s Degree in Business Marketing and comes from a family of entrepreneurs. The recruitment niche she tapped into was due to the high demand of Scientists globally and she felt that recruitment services focusing within the scientific arena were much needed. She has built a reputation within the industry as the go-to Recruitment firm for Scientists of all levels. Dawn is passionate about contributing to the industry by finding Scientists career opportunities globally and helping clients find the best talent across the board.

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Liquid biopsy is a new technology for detection and analysis of biomarkers in blood or other body fluids without the need of invasive procedures. One important analyte is cell-free circulating DNA (cfDNA). The main challenges in working with cfDNA are the low concentration (1 - 50 ng/ml) and the high degree of fragmentation of cfDNA (< 500 bp). An additional complication is that the circulating tumor DNA only accounts for up to 20 % of the total cfDNA. Therefore processing higher sample volumes, typically in the range of several milliliters, is required.

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As companies and institutions from across the globe converge on San Diego for the annual ACCC meeting there is a common thread between them all – there is a drastic need for more trained professionals.

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SynAbs is proud to announce strategic deal with successful company Dianova. Dianova has already demonstrated a huge knowledge and expertise in monoclonal antibodies and will consequently extend its catalogue with unique mAbs references from SynAbs. Under the terms of the agreement, Dianova will have access to unique portfolio of rats and guinea pigs mAbs to address German territory needs in R&D and IVD fields.

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The SME of Besançon bought Diaclone in 2012, then participated in the creation of SynAbs Belgian start-up in 2015. Business is booming.

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The Diatron, global provider of hematology and clinical chemistry analyzers, will display their Aquila 3-part differential hematology analyzer (60 samples /hour throughput) at the upcoming AACC Meeting in San Diego, California on the 1-3 of August, 2017.

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SJK Global Vanilmandelic Acid (VMA) Assay is a quantitative immunoassay for measuring VMA in human urine.

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Findings presented at the American Society for Microbiology’s ASM Microbe conference show that the ultra-sensitive Clostridium difficile toxin A/B assay in development for use on the Sgx Clarity™ system offers excellent sensitivity and may be a critical tool for improving the diagnosis of this life-threatening infection. The Sgx Clarity system is a fully-automated, in vitro diagnostics platform powered by Single Molecule Counting technology.

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Yaskawa Motoman offers track-based specimen processing solutions that improve speed, capacity and accuracy for labor-intensive, high throughput areas of the clinical diagnostic lab. These fully integrated pre- and post-analytic automation solutions can enable high throughput with minimal staffing.