By combing through the entire genetic sequences of a person with a lung scarring disease and 13 of the person’s relatives, Johns Hopkins Medicine researchers say they have found a coding error in a single gene that is likely responsible for a rare form of the disease and the abnormally short protective DNA caps on chromosomes long associated with it.
Mayo Clinic在佛罗里达州新建的探索与创新楼于8月22日（周四）正式开放。在此运用的先进技术将增加可供移植的肺器官数量。另外，这栋占地75,000平方英尺的大楼还会配设创新型生命科学孵化器，让企业家能够利用各项资源将医疗解决方案推向市场。
A new development has revealed a previously unknown characteristic of the vaping-related respiratory illness that has been emerging in clusters across the U.S. in recent months. The finding may allow doctors to definitively diagnose the nascent syndrome more quickly and provide the right treatment sooner. University of Utah Health investigators reported the findings in a letter published in the New England Journal of Medicine.
Das neue Entdeckungs- und Innovationsgebäude der Mayo Clinic in Florida eröffnete am Donnerstag, dem 22. August. Hier wird durch wegweisende Technologie die Anzahl der für die Transplantation verfügbaren Lungen erhöht. In dem rund 7000 Quadratmeter großen Gebäude wird sich auch ein innovativer Life Sciences Incubator befinden, der Unternehmer mit Ressourcen verbindet, um medizinische Lösungen auf den Markt zu bringen.
Le nouveau Discovery and Innovation Building de la Mayo Clinic en Floride, un bâtiment dédié à la recherche et à l’innovation, a ouvert ses portes le jeudi 22 août. Dans cet endroit, une technologie novatrice augmentera le nombre de poumons disponibles pour les transplantations.
O novo Edifício de Descobertas e Inovação da Mayo Clinic na Flórida foi inaugurado na quinta-feira, 22 de agosto. Nele, a tecnologia de ponta aumentará o número de pulmões disponíveis para transplante.
News and interview opportunities at Seattle Cancer Care Alliance
E-cigarette usage may impair fertility and pregnancy outcomes, according to a mouse study published in the Journal of the Endocrine Society.
Immune checkpoint inhibitors are a type of therapy that uses the immune system to fight cancer. They have been hailed as game changing, garnering a Nobel Prize last year and quickly becoming the standard of care for many tumor types such as melanoma and certain lung and head and neck cancers.
Researchers at The University of Texas at El Paso’s School of Pharmacy have been awarded $1.8 million from the National Heart, Lung and Blood Institute (NHLBI) of the National Institutes of Health (NIH) to study the effects of thirdhand smoke on platelet function and cardiovascular disease such as heart attack and stroke.
Henry Ford Cancer Institute is the first-in-Michigan and second-in-the-world to complete an innovative cancer treatment known as Spinal Laser Interstitial Thermal Therapy (SLITT), which destroys cancer cells that are adjacent to the spine without the need for open surgery.
Study identifies possible gene variants that determine whether a person infected with TB will progress rapidly to active disease.
The pending deal for Altria to purchase 35% of Juul Labs should serve as a “wake-up call” for the careful monitoring of competition in the nicotine delivery market, and for evaluating how regulations and policies impact cigarette and non-cigarette firms selling alternative nicotine delivery products, says a Georgetown University professor.
The presence of chemicals made as the body breaks down fats, proteins, and carbohydrates can predict whether Sept. 11, 2001 first responders exposed to toxic dust at the World Trade Center site subsequently develop lung disease, a new study finds.
With wildfires from the Arctic to the Amazon, the issue of wildfires, and the resulting smoke, is in the news. Dr. Cora Lynn Sack, a UW Medicine pulmonologist, comments.
The American Thoracic Society has published an official clinical guideline on laboratory diagnosis of fungal infections in pulmonary and critical care medicine in the Society’s Aug. 30 American Journal of Respiratory and Critical Care Medicine.
El jueves 22 de agosto, se inauguró en Mayo Clinic de Florida el nuevo edificio “Descubrimientos e Innovación”, donde mediante tecnología pionera se incrementará la cantidad de pulmones disponibles para trasplante.
Median survival after lung transplant is less than six years. To see what might help lung transplant recipients live longer, University of Maryland School of Medicine researchers analyzed US lung transplant data, focused on immunosuppression regimes, and found a drug combination that appears to significantly extend patient survival.
Though typically harmless, Legionella bacteria can be deadly when it causes Legionnaires’ disease, a pneumonia-like lung infection. The elderly and people with weakened immune systems are the most susceptible to the disease, yet there isn’t much research to show whether Legionella bacteria may be found in respiratory care devices.
Patients with non-small cell lung cancer (NSCLC) now have more improved treatment options compared to standard of care with the addition of several new agents called immune-checkpoint inhibitors (ICI). Despite these changes, many patients still develop progressive disease after ICI treatment. In a new study published in Clinical Cancer Research, Moffitt Cancer Center researchers describe promising results from an early clinical trial that may offer patients who progress after ICI an additional treatment option.
Mayo Clinic in Florida's new Discovery and Innovation Building opened on Thursday, Aug. 22. Here, pioneering technology will increase the number of lungs available for transplant. The 75,000-square-foot building also will house an innovative Life Sciences Incubator that connects entrepreneurs with resources to bring medical solutions to market.
UNC scientists found that the lungs of vapers – like the lungs of smokers – have elevated levels of protease enzymes, a condition known to cause emphysema in smokers. The researchers also found that the nicotine in vaping liquids is responsible for the increase in protease enzymes.
Researchers at Rutgers and other institutions have discovered how muscle contraction (bronchospasm) in the airway, which cause breathing difficulty in people with asthma, occur by creating a microdevice that mimics the behavior of the human airways. The study, published in the journal Nature Biomedical Engineering, could lead to new treatment strategies for respiratory diseases, said co-author Reynold Panettieri, director of the Rutgers Institute for Translational Medicine and Science.
The amount of opioids prescribed for patients after heart and lung surgery has a direct relationship with the risk for opioid dependency and “persistent opioid use” several months after the operation.
جاكسونفيل، فلوريدا - يشتهر سرطان الرئة الغدي بسوء التنبؤات بخصوص سَيْر المرض، وهو النوع الأكثر شيوعًا من سرطان الرئة، والمسؤول عن حوالي 4 من 10 حالات تشخيص، وفقًا للمعهد القومي للسرطان. يمكن للباحثين في حرم Mayo Clinic في فلوريدا الآن التمييز بين مسارين يمكن لهذا السرطان المميت أن يتطور من أيهما، ويصرحون أن اكتشافهم قد يساعد المرضى في المستقبل. وتظهر النتائج في خلايا السرطان.
The number of teens and young adults treated for severe respiratory injury after e-cigarette use is increasing at Monroe Carell Jr. Children’s Hospital at Vanderbilt, which is consistent with a nationwide trend that led to a recent communication to physicians from the Centers for Disease Control and Prevention (CDC).
Lung cancer is the second most common cancer found in both men and women. It is estimated there will be roughly 228,000 new lung cancer cases this year, and nearly 30% of those patients will have mutations in the KRAS pathway. This type of mutation makes the cancer more aggressive and difficult to treat. Researchers at Moffitt Cancer Center are hoping to change that. In a new study published in Cancer Research, the team discovered a new treatment approach that may help this group of patients.
A new study from Washington University School of Medicine in St. Louis supports evidence that children with mild asthma can effectively manage the condition by using their two inhalers — one a steroid and the other a bronchodilator — when symptoms occur. This is in contrast to the traditional method of using the steroid daily, regardless of symptoms, and the bronchodilator when symptoms occur. The as-needed use of both inhalers is just as effective for mild asthma as the traditional protocol, according to the investigators.
Castleman Disease patients who do not respond to the only drug currently approved by the FDA may have another option that targets a specific pathway called PI3K/Akt/mTOR
Long-term exposure to air pollution was linked to increases in emphysema between 2000 and 2018, according to a new study funded by the National Institute of Environmental Health Sciences (NIEHS) and the National Heart, Lung, and Blood Institute (NHLBI), both part of the National Institutes of Health.
Air pollution—especially ozone air pollution which is increasing with climate change—accelerates the progression of emphysema of the lung, according to a new study led by the University of Washington, Columbia University and the University at Buffalo.
Long-term exposure to outdoor air pollutants, especially the pollutant ozone, accelerates the development of emphysema and age-related decline in lung function, even among people who have never smoked, according to a study published in the Journal of the American Medical Association.
$3.4 Million Study to Understand Why Older Adults Have Worse Asthma Outcomes
Irvine, Calif., Aug. 12, 2019 – Hookah waterpipe use has grown in popularity in recent years – 1 in 5 college students in the U.S. and Europe have tried it – but the practice could be more dangerous than other forms of smoking, according to a first-of-its-kind study by researchers at the University of California, Irvine, published recently in Aerosol Science and Technology.
Boehringer Ingelheim and MD Anderson have announced a new multi-year partnership to conduct collaborative research, combining the drug-development capabilities of MD Anderson with the pipeline of novel medicines from Boehringer Ingelheim.
Conhecido por seu prognóstico precário, o adenocarcinoma de pulmão é o tipo de câncer de pulmão mais comum, responsável por aproximadamente 4 de 10 diagnósticos, de acordo com o National Institute of Cancer. Os pesquisadores do campus da Flórida da Mayo Clinic agora podem distinguir entre duas vias onde esse câncer fatal pode se desenvolver.
Das Lungenadenokarzinom ist bekannt für seine schlechte Prognose und laut National Cancer Institute mit etwa 4 von 10 Diagnosen die häufigste Form von Lungenkrebs. Forscher auf dem Mayo Clinic Campus in Florida können nun zwischen zwei Signalwegen unterscheiden, auf denen sich dieser tödliche Krebs entwickeln kann.
美国国家癌症研究所的研究表明，肺腺癌是最常见的肺癌类型，且公认预后较差，每10例肺癌诊断中约有4例为肺腺癌。Mayo Clinic佛罗里达院所的研究人员现在可以区分这种致命癌症的两种可能发生途径。他们表示其发现可以帮助未来的患者。研究结果发表在Cancer Cell（《癌细胞》）期刊上。
Connu pour son pronostic défavorable, l'adénocarcinome pulmonaire est le type le plus commun de cancer du poumon, responsable d'environ 4 diagnostics sur 10, selon l'Institut national du cancer. Des chercheurs du campus de Floride de la Mayo Clinic peuvent désormais distinguer deux voies de développement de ce cancer mortel.
Certain traits may define a type of obstructive sleep apnea that can be effectively treated with an oral appliance, according to new research published online in the Annals of the American Thoracic Society.
Despite improved knowledge of the molecular alterations in SCC, little is understood about how the alterations contribute to the development of the cancer and how potential vulnerabilities could be exploited to treat the disease. Researchers in Moffitt Cancer Center’s Lung Cancer Center of Excellence took a closer look at SCC tumors to determine if their characteristics had an impact on patient outcomes. The findings were published today in Nature Communications.
UW Medicine’s lung-transplant team, the only such providers in the Pacific Northwest, performed their 1,000th transplant on July 7, 2019. Ten other U.S. programs have reached such a milestone. Lindsey Decker, 33, of Tri-Cities, Washington, received two donor lungs and was patient No. 1,000.
– Old lungs are not as capable as young lungs of fighting off an infection of the bacteria that causes tuberculosis (TB), placing seniors at a greater risk of developing TB. The microbe that causes this infectious disease, Mycobacterium tuberculosis (Mtb), currently kills more people in the world than any other pathogen. Texas Biomed researchers published an article in the Journal of Infectious Diseases in July 2019. The study details an experiment that took place in vitro (in the lab) and in vivo (in animals) that showed fluid in the lining of the lungs plays a big role in the elderly’s susceptibility to infection with the bacterium Mtb.
The Society of Thoracic Surgeons—along with its charitable arm, The Thoracic Surgery Foundation (TSF)—and the American Lung Association have established a new grant, the Lung Cancer Research Award, designed to support investigators performing impactful lung cancer research.
A new study from Aarhus University Hospital and Aarhus University, Denmark, has shown that probably 1 in 4 people in the world carry the tuberculosis bacterium in the body.
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