Researchers at the University of Utah Health are looking to the salience network of the brain to develop music-based treatments to help alleviate anxiety in patients with dementia. Their research will appear in the April online issue of The Journal of Prevention of Alzheimer's Disease.
People with restless legs syndrome may have changes in a portion of the brain that processes sensory information, according to a study published in the April 25, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology.
For most people, it’s better to start taking drugs for multiple sclerosis (MS) early on rather than letting the disease run its course, according to a new guideline for treating MS from the American Academy of Neurology. The guideline is published in the April 23, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology, and presented at the 70th AAN Annual Meeting in Los Angeles, April 21 to April 27, 2018. The guideline is endorsed by the Multiple Sclerosis Association of America and the National Multiple Sclerosis Society.
A coalition of brain scientists and civic leaders, including Mayor Kevin Faulconer and county Supervisors Dianne Jacob and Kristin Gaspar, announced that the federal government has awarded a $1.3 million grant to Sanford Burnham Prebys Medical Discovery Institute to advance the local search for a cure for Alzheimer's.
People with tremors in their hands from a condition called essential tremor may find some relief from a new, non-invasive type of nerve stimulation, according to a preliminary scientific abstract released today that will be presented at the American Academy of Neurology’s 70th Annual Meeting in Los Angeles, April 21 to 27, 2018.
A preliminary study suggests that an investigational drug may help increase protein levels in babies with spinal muscular atrophy. The open-label study is released today and will be presented at the American Academy of Neurology’s 70th Annual Meeting in Los Angeles, April 21 to 27, 2018.
People who have been diagnosed with a mild concussion, or mild traumatic brain injury, may have a 56 percent increased risk of developing Parkinson’s disease, according to a study published in the April 18, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology.
People who have tried unsuccessfully to prevent migraine with other treatments may find relief with a drug called erenumab, according to a preliminary study released today that will be presented at the American Academy of Neurology’s 70th Annual Meeting in Los Angeles, April 21 to 27, 2018.
Researchers announce new definition of Alzheimer’s disease.
Sitting, like smoking, increases the risk of heart disease, diabetes and premature death. Researchers at UCLA wanted to see how sedentary behavior influences brain health, especially regions of the brain that are critical to memory formation.
On April 18-22, 2018, the UCI Center for the Neurobiology of Learning and Memory will host 800 of the world’s foremost brain scientists for the 2018 International Conference on Learning and Memory. Scientists at the conference will present late-breaking research on topics such as Alzheimer’s disease, drug addiction, exercise and the brain, depression, stress and more.
Entering menopause at a later age may be associated with a small benefit to your memory years later, according to a study published in the April 11, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology.
A rare, inherited neurodegenerative disorder will soon be the focus of an international clinical research effort led by Houston Methodist and funded by the National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health.
Researchers at McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth) have been awarded grants from the National Institutes of Health (NIH) to explore how the buildup of protein deposits in the brain can trigger dementia and stroke.
For the first time, a team of neuroscientists at Beth Israel Deaconess Medical Center (BIDMC) has demonstrated circadian control of aggression in male mice and identified the specific neurons and circuitry regulating the daily pattern.
Studying data from more than 125,000 individuals, an international team of researchers led by scientists at Washington University School of Medicine in St. Louis has identified genetic links between amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. The link between the seemingly unrelated disorders suggests that some drugs developed to treat ALS also may work against frontotemporal dementia and vice versa.
The Lewy Body Dementia Association (LBDA) named Florida Atlantic University as a LBDA Research Center of Excellence (RCOE), a nationwide collaboration of 24 pre-eminent academic medical research centers.
The Lewy Body Dementia Association has designated Georgetown University Medical Center as a “Research Center of Excellence.”
A University of Delaware researcher is investigating a novel compound's role in combating age-related chronic diseases like mild cognitive disorder and dementia. The study is funded by a grant from the National Institute on Aging.
The Lewy Body Dementia Association (LBDA), announced today that UC San Diego Health has been named a LBDA Research Centers of Excellence (RCOE), a partnership of 24 pre-eminent academic medical research centers across the United States. LBDA is a leading advocacy group dedicated to raising awareness and advancing research and treatment of Lewy body dementia (LBD).
Lewy body dementia is the second most common type of progressive dementia after Alzheimer’s disease, but it is underdiagnosed, says Bradley Boeve, M.D., a Mayo Clinic neurologist. A new program among research centers across the country intends to change that.
Alzheimer’s, Parkinson’s and Huntington’s disease may have more in common than their effects on the functions of the brain and spinal cord. And finding that common thread could lead to a treatment that could work for all three.
Special report details serious concerns that medical community would be able to do much, if anything, to assist people in event of major nuclear event. Prevention is best option as well as carefully conceived, long-term plan within the public education system to provide lessons on radiation biology
Scientists at Wake Forest Baptist Medical Center and the University of Southern California (USC) have demonstrated the successful implementation of a prosthetic system that uses a person’s own memory patterns to facilitate the brain’s ability to encode and recall memory.
Taking menopausal hormone therapy soon after menopause to relieve symptoms may also benefit the brain, according to a study published in the March 21, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Alzheimer's disease is characterized by clumps of two proteins – amyloid beta and tau – in the brain, but the link between the two has never been entirely clear. Now, researchers at Washington University School of Medicine in St. Louis have shown that people with more amyloid in the brain produce more tau, which could lead to new treatments for the disease based on targeting the production of tau.
A UT Southwestern study in mice provides new clues about how a class of anti-rejection drugs used after organ transplants may also slow the progression of early-stage Alzheimer’s disease.
A compound in beets that gives the vegetable its distinctive red color could eventually help slow the accumulation of misfolded proteins in the brain, a process that is associated with Alzheimer’s disease. Scientists say this discovery could lead to the development of drugs that could alleviate some of the long-term effects of the disease, the world’s leading cause of dementia.
Dr. Amy Hunter, a full-time faculty member and a part-time practitioner, is focused on improving the quality of care for older adults.
The American Academy of Neurology and the American Brain Foundation are awarding an Illinois researcher the 2018 Potamkin Prize for Research in Pick’s, Alzheimer’s and Related Diseases for his work in dementia research. David A. Bennett, MD, of Rush University Medical Center in Chicago and a member of the American Academy of Neurology, will be honored at the American Academy of Neurology’s 70th Annual Meeting in Los Angeles, April 21-27, 2018.
While there has been an increased focus on person-centered models of care transition for cognitively intact older adults from hospital to home, little is known about the core elements of successful transitions in care specifically for persons with dementia.
Women with high physical fitness at middle age were nearly 90 percent less likely to develop dementia decades later, compared to women who were moderately fit, according to a study published the March 14, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study measured the women’s cardiovascular fitness based on an exercise test.
African Americans with a common genetic variation are at increased risk for developing Alzheimer’s disease, while European Americans with the same variation are not, according to a study led by researchers at Rush University Medical Center. They published the study results in the February 22 issue of the Journal of Clinical Endocrinology and Metabolism.
Dr. David Bennett has been awarded the 2018 Potamkin Prize for Research in Pick’s, Alzheimer’s and Related Diseases by the American Academy of Neurology and the American Brain Foundation. Sometimes referred to as the Nobel Prize of Alzheimer’s research, the Potamkin Prize is an internationally recognized tribute in the field.
UCLA researchers engineered mice to produce more TREM2, a gene tied to Alzheimer’s disease
As we get older, it’s not uncommon to experience “senior moments,” in which we forget where we parked our car or call our children by the wrong names. And we may wonder: Are these memory lapses a normal part of aging, or do they signal the early stages of a severe disorder such as Alzheimer’s disease? Currently, there’s no good way to tell.
SBP researchers have revealed how TREM2, a receptor found on immune cells in the brain, interacts with toxic amyloid beta proteins to restore neurological function. The research suggests boosting TREM2 levels in the brain may prevent or reduce the severity of neurodegenerative disorders including Alzheimer’s disease.
A sizable percentage of elderly patients with blood-related cancers such as leukemia and multiple myeloma are apt to show signs of diminished cognitive functioning
Researchers profiled the epigenomic landscape of Alzheimer’s brains, specifically in one of the regions affected early in AD, the lateral temporal lobe. They compared these to both younger and elderly cognitively normal control subjects. The team described the genome-wide enrichment of a chemical modification of histone proteins that regulates the compaction of chromosomes in the nucleus. Changes along the genome in disease versus normal aging brains may signify places for future drug development.
For the first time, an international team of scientists, led by researchers at University of California San Diego School of Medicine, have determined that an Alzheimer’s disease (AD) polygenic risk score can be used to correctly identify adults with mild cognitive impairment (MCI) who were only in their 50s. MCI is considered a precursor to AD.
People with increasing total cholesterol aged 85 and older had a reduced risk for marked cognitive decline compared to people 75-84 whose risk was significantly elevated.
People who suffer from insomnia could be cured of the dangerous sleep disorder by following a six-week, drug-free regimen recommended by a sleep physician at Virginia Mason Medical Center.
Concussions and other traumatic brain injuries may increase the risk of developing Alzheimer’s disease earlier in life, according to a study from UT Southwestern’s Peter O’Donnell Jr. Brain Institute.
A strict gluten-free diet may help protect against the nerve pain that some people with gluten sensitivity experience, according to a preliminary study released today that will be presented at the American Academy of Neurology’s 70th Annual Meeting in Los Angeles, April 21 to 27, 2018.
People whose eyes show signs of small changes in blood vessels at age 60 may be more likely to develop thinking and memory problems by the time they are 80 than people with healthy eyes, according to a study published in the February 28, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Hilary Van Horn, whose stepdad is suffering from Lewy body dementia, challenges everyone to make an "Earth Angel" in an awareness and fundraising campaign for the Penn Memory Center.
A UAB study shows that a gene therapy approach can help neurons remove lipofuscin, or cellular debris, in mouse models for frontotemporal dementia. The study added a gene that encodes for the missing protein progranulin.
Some people with a certain type of hearing loss may be more likely to also have the memory loss and thinking problems called mild cognitive impairment, according to a preliminary study released today that will be presented at the American Academy of Neurology’s 70th Annual Meeting in Los Angeles, April 21 to 27, 2018. Hearing loss is one of the most common disabilities in elderly people, affecting about one-third of people over age 65.
A team of researchers from ORNL and the University of Alabama at Birmingham recently developed the antioxidant manganoporphyrin, a new polymer that could potentially improve drug delivery methods and other biomedical applications. Using neutrons, they studied the strength and efficiency of a compound made from this material and tannic acid, a natural antioxidant.
The finding “opens up a whole new research area to look at neuroinflammation in the context of Alzheimer’s and Parkinson’s,” the lead researcher says. “But the clinical impact will be in many, many different areas.”
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