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Stem Cells

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Medicine

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Linda Resar, Linda M. S. Resar, Stem Cells, Intestinal, Niche, Transgenic, HGMA1, Cancer, colon

Single Gene Encourages Growth of Intestinal Stem Cells, Supporting "Niche" Cells--and Cancer

A gene previously identified as critical for tumor growth in many human cancers also maintains intestinal stem cells and encourages the growth of cells that support them, according to results of a study led by Johns Hopkins researchers. The finding, reported in the Apr. 28 issue of Nature Communications, adds to evidence for the intimate link between stem cells and cancer, and advances prospects for regenerative medicine and cancer treatments.

Medicine

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arthritis, , Induced Pluripotent Stem Cells, Tnf Alpha, Inflammation, Rheumatoid Arthris

Stem Cells Edited to Fight Arthritis

Using CRISPR technology, a team of researchers led by Farshid Guilak, PhD, at Washington University School of Medicine in St. Louis, rewired stem cells' genetic circuits to produce an anti-inflammatory arthritis drug when the cells encounter inflammation. The technique eventually could act as a vaccine for arthritis and other chronic conditions.

Medicine

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Muscle Regeneration, Muscle Repair, Aging, Sarcopenia, Muscle Loss, Duchenne Muscular Dystrophy

New Insights on Triggering Muscle Formation

A team of scientists led by Lorenzo Puri, M.D., Ph.D., has identified a previously unrecognized step in stem cell-mediated muscle regeneration. The study, published in Genes and Development, helps explain why muscle stem cells lose the ability to generate new muscle as they age and provides insight into accelerated muscle stem cell aging in muscular dystrophy.

Medicine

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Stem Cells, Epigenetic, Metabolism, Biology, Medicine, Cancer, Genome

Einstein’s 2017 Stem Cell Symposium Spotlights Epigenetics and Metabolism

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On Monday, April 24, the Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research at Albert Einstein College of Medicine will host its third Stem Cell Symposium, focusing on the importance of cell metabolism and epigenetics. Leading scientists from the U.S., Japan and Germany will present their latest research and describe the hurdles to translating new finding into therapeutics.

Science

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Neurobiolgy, Axons, Biology, Stem Cells, Neuroscience, nervous system circuits, Nervous System, Neuron, Axon Guidance, Neural Progenitor Cells, Nerve Regeneration, Nerve Regrowth, stem cells and diabetes, Netrin 1, netrin-1

Study Overturns Seminal Research About the Developing Nervous System

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New research by scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA overturns a long-standing paradigm about how axons grow during embryonic development. The findings of the study, led by Samantha Butler, associate professor of neurobiology, could help scientists replicate or control the way axons grow, which may be applicable for diseases that affect the nervous system, such as diabetes, as well as injuries that sever nerves.

Medicine

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Stem Cells, Clinical Trial, Retinitis Pigmentosa, California, California Institute For Regenerative Medicine, Cirm, Phase 2b, Retinal Diseases

Powered by CIRM Grant, jCyte Launches New Clinical Trial

Cell-based therapy company jCyte is launching a Phase 2b clinical trial to study the effectiveness of its developmental therapy for retinitis pigmentosa.

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Wills Eye Experts Can Speak to the Media on Reprogrammed Stem Cells as a Treatment for Macular Degeneration

Science

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biochemical engineering, stem cell technology , Graphene, Mechanical Engineering

Researchers Use Graphene, Electricity to Change Stem Cells for Nerve Regrowth

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Two Iowa State research groups are combining their expertise to change stem cells for nerve regrowth. The groups -- one led by a mechanical engineer and the other by a chemical engineer -- just published their findings in Advanced Healthcare Materials.

Medicine

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hematopoetic stem , Hematopoietic Stem Cells, Stem Cells, Blood Developement, Blood Cells, Transplant, Zebrafish model, Zebrafish, St. Jude Children's Research Hospital, Hematology

Time-Lapse Video Reveals Cells Essential for ‘Birth’ of Blood Stem Cells

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St. Jude Children’s Research Hospital study examines origin of blood stem cells during development and offers clues for making “donor blood” in the laboratory for therapeutic use

Medicine

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Regenerative Medicine, Stem Cells

Turning Skin Cells Into Blood Vessel Cells While Keeping Them Young

Researchers from the University of Illinois at Chicago have identified a molecular switch that converts skin cells into cells that make up blood vessels, which could ultimately be used to repair damaged vessels in patients with heart disease or to engineer new vasculature in the lab.







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