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Detroit Medical Center, Down Syndrome, ALL acute lymphoblastic leukemia, AML acute myeloid leukemia, Dr Jeffrey Taub, Pediatric Cancer Treatment

Detroit Pediatric Oncologist Leads Largest Single Study on Survival Outcomes for Children with Down Syndrome and AML or ALL

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Jeffrey W. Taub, M.D., FAAP, chief, Division of Oncology, at the DMC's Children’s Hospital of Michigan was the principal investigator of the study, which enrolled 204 children from 2007-2011 through the Children’s Oncology Group (COG), an international organization which links all major pediatric oncology centers in the U.S., Canada and other countries to develop treatments for children with cancer.

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Hemophilia, Emicizumab, a novel monoclonal antibody

Disruptive Technology for the Treatment of Hemophilia

An international team of hematologists including Guy Young, MD, of Children’s Hospital Los Angeles, has found that in patients with hemophilia A with inhibitors, a novel therapy called emicizumab, decreases incidence of bleeding episodes by 87%.

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Diabetes Complications Are a Risk Factor for Repeat Hospitalizations, Study Shows

ROCHESTER, Minn. — For patients with diabetes, one reason for hospitalization and unplanned hospital readmission is severe dysglycemia (uncontrolled hyperglycemia – high blood sugar, or hypoglycemia – low blood sugar), says new research published in the Journal of General Internal Medicine.

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Charles Mullighan, St. Jude Children's Research Hospital, Jinghui Zhang, genomic sequencing, Acute Lymphoblastic Leukemia, genomic analysis, T-ALL, T-All Leukemia

First Large-Scale Genomic Analysis of Key Acute Leukemia Will Likely Yield New Therapies

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Charting the genomic landscape of T-lineage acute lymphoblastic leukemia patients revealed insights that will guide research and help to lay the foundation for more targeted therapy.

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Catheter, Bloodstream Infections

Catheters Linked to Most Bloodstream Infections in Dialysis Patients

• Most bloodstream infections in dialysis patients continue to occur in those with central venous catheters used to access their blood. The findings come from 2014 data from US dialysis facilities. • Staphylococcus aureus was the most commonly isolated pathogen that caused bloodstream infections, and in many cases they were antibiotic-resistant.

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Blood Clot, Deep Vein Thrombosis, DVT, Pulmonary Embolism, Blood Thinners

The Medical Minute: Many Treatments Can Mitigate Blood Clot Dangers

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Deep vein thrombosis, or DVT, describes the type of clots that can form in blood vessels of the arms or legs. Sometimes they can travel to the lungs, creating serious complications or even death.

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Grant, Breast Cancer, Blood Clot

CWRU Researcher Awarded Over $4.7 Million to Develop Drug-Delivery Nanotechnology

Nicole F. Steinmetz, PhD, director of the Center for Bio-Nanotechnology at Case Western Reserve School of Medicine, has received two major grants from the National Institutes of Health to develop microscopic drug-delivery systems for patients living with breast cancer, and patients at risk for serious blood clots.

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Blood Pressure, Chronic Kidney Disease

Intensive Blood Pressure Lowering Benefits Patients with Chronic Kidney Disease

• In individuals with chronic kidney disease, targeting a systolic blood pressure to <120 mm Hg resulted in lower risks of cardiovascular events and premature death, compared with standard targeting to <140 mm Hg. • There was a slightly faster decline in kidney function in the intensive group, but no increase in rates of kidney failure or serious adverse events.

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Wolters Kluwer, HemaSphere, European Hematology Association

Wolters Kluwer and European Hematology Association Launch Hemasphere

Wolters Kluwer, a leading global provider of information and point of care solutions for the healthcare industry, and the European Hematology Association (EHA) are pleased to announce the launch a new open access journal, HemaSphere. Part of the Lippincott portfolio, the journal was launched today at the 22nd Annual Congress of the European Hematology Association in Madrid.

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HIV, AIDS, Cytomegalovirus, Mother To Child Transmission, Infant, CMV, brain damage infants, Fetal Growth, Liver Damage, lung damage, spleen damage, Hearing Loss, HIV Positive Women

HIV-Positive Women with Cytomegalovirus Likelier to Pass Virus That Causes AIDS to Infant

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HIV-positive women with CMV in their urine at the time of labor and delivery are more than five times likelier than HIV-positive women without CMV to transmit HIV to their infants. The research also found that they are nearly 30 times likelier to transmit CMV to their infants.







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