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Genetics

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Medicine

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Gene Therapy, myotubular myopathy, Children, Pediatric, ASPIRO, Virus

New Gene Therapy Trial for Severe Neuromuscular Disorder in Children

Ann & Robert H. Lurie Children’s Hospital of Chicago is one of the few centers participating in ASPIRO, an international Phase 1/2 clinical trial of a gene therapy product called AT132 for X-linked myotubular myopathy – a rare disease characterized by severe muscle weakness, breathing difficulty and early death.

Medicine

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Dna Repair, Cancer, alkylating agents

How Cells Detect, Mend DNA Damage May Improve Chemotherapy

Human cells have a way of detecting and mending DNA damage caused by some common chemotherapy drugs, according to a new study from Washington University School of Medicine in St. Louis. The findings could have important implications for treating cancer.

Medicine

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Mental Health, Bipolar Disorder, Schizophrenia, Lithium, Genetics, Psychiatry

Gene Breakthrough on Lithium Treatment for Bipolar Disorder

Genes linked to schizophrenia in psychiatric patients suffering from bipolar disorder are the reason why such patients don't respond to the "gold standard" treatment for bipolar – the drug lithium – according to international research led by the University of Adelaide.

Medicine

Science

Life

Business

Law and Public Policy

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Rural Health, Healthcare, Robert Wood Johnson Foundation, National 4-H Council, Appalachia, Health Disparities, Racial Disparities, Prevention, Health Policy

Closing the Rural Health Gap: Media Update from RWJF and Partners on Rural Health Disparities

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Rural counties continue to rank lowest among counties across the U.S., in terms of health outcomes. A group of national organizations including the Robert Wood Johnson Foundation and the National 4-H Council are leading the way to close the rural health gap.

Science

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Biology, Reproduction, Sperm, egg, Sea Urchins, Florida State University, Don Levitan

Rival Sperm and Choosy Eggs: FSU Researcher Finds That When Sperm Compete , Eggs Have a Choice.

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The delicately mannered dance between discerning eggs and vying sperm is more complicated than scientists once believed, and it may hold secrets about the evolution of new species.

Medicine

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Neuroscientists Find Promise in Intervention to Normalize Biological Functions in Fragile X Mice

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A team of neuroscientists have developed an intervention that normalizes multiple biological functions in mice afflicted with Fragile X Syndrome.

Medicine

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Biology, Molecular Biology, Genetics, Medicine & Health, Nicotine, Addiction, Cigarettes, Smoking

Tiny Worms May Offer New Clues About Why It's So Hard to Quit Smoking

Researchers at the University of Michigan Life Sciences Institute found that a previously dismissed genetic mechanism may contribute to nicotine dependence, and to the withdrawal effects that can make quitting smoking so difficult.

Medicine

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Muscular Dystrophy, FSHD

SLU Researcher Draws Bulls Eye Around Muscular Dystrophy Drug Targets

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Saint Louis University scientist Francis M. Sverdrup, Ph.D., studies an inherited type of muscular dystrophy that typically begins with weakness in the face and shoulders before spreading to all skeletal muscles.

Science

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Butterflies, Insects, Genetics, Evolution, Mimicry

How a “Flipped” Gene Helped Butterflies Evolve Mimicry

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Scientists from the University of Chicago analyzed genetic data from a group of swallowtail species to find out when and how mimicry first evolved, and what has been driving those changes since then.

Medicine

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Sickle Cell Disease, Hemoglobin, Haptoglobin, Acute Chest Syndrome, Genotype, Genetic Testing, Physiological and Pathophysiological Consequences of Sickle Cell Disease Conference

Gene Marker Could Identify Sickle Cell Patients with Highest Risk of Complications

Researchers have found a genotype that could help identify sickle cell disease (SCD) patients at greatest risk of developing disease-related complications. The findings will be presented at the APS Physiological and Pathophysiological Consequences of Sickle Cell Disease conference.







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