Feature Channels: Epilepsy

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This year’s theme for International Epilepsy Day, “Step Up Against Stigma”, provides a platform to dispel myths with facts.

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Un equipo de investigadores visito dos centros de atencion primaria de salud en Bhimaravam para evaluar la atencion proporcionada a las personas con epilepsia a traves del sistema de atencion primaria de salud.

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Human cells are often a mixture of both abnormal and normal DNA – a mosaic, so to speak, and like the art form, this complex montage is difficult to understand. Neuroscience researchers are training computers to unveil new methods for DNA mosaic recognition.

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An international consortium led by UC San Diego has identified at least some of the genetic drivers of a mysterious form of pediatric epilepsy.

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Among people with epilepsy, Black, Latino and Native Hawaiian and Other Pacific Islander people are less likely to be prescribed newer drugs than white people, which can be a marker of the quality of care, according to a study published in the January 11, 2023, online issue of Neurology® Clinical Practice, an official journal of the American Academy of Neurology.

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In this episode of Sharp Waves, the ILAE podcast, Dr. Maryam Nabavi Nouri talks with Dr. Konrad Wagstyl about the MELD Project, an open-science consortium using deep learning principles to develop automated lesion detection of clinical MRI data.

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Following a modified Atkins diet high in fat and low in carbohydrates plus taking medication may reduce seizures in people with tough-to-treat epilepsy, according to a study published in the January 4, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.

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Dr. Alina Ivaniuk talks with Dr. Neuray about her career path from medical school to industry CEO. They discuss the power of peer mentoring, ways to improve medical education, and finding the courage to accept change.

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A roundup of the latest medical discoveries and faculty news at Cedars-Sinai.

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First-line immunotherapy and the ketogenic diet are two main recommendations for treatment of NORSE of unknown cause, according to results from an international consensus group. Dr. Maryam Nabavi Nouri interviews first author Dr. Ronny Wickstrom.

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Hours from the nearest city in India, down a pothole-studded road framed by fish farms, primary care centers in Andra Pradesh provide service to tens of thousands of people. How do these centers care for people with epilepsy, and what challenges do they face?

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For the first time, scientists have recorded human nerve cells firing together in flexible assemblies, a process that appears necessary to successfully encode long-term memories, a study led by UT Southwestern researchers reports.

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Nurses play crucial roles in epilepsy care, but their perspectives and voices are often missing. The ILAE Nursing Section is a “home” for nurses around the world who care for people with epilepsy. Sharp Waves talked to section leaders.

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A five-year, nearly $3.5 million grant to study the mechanisms of brain receptors involved in neurological disorders such as learning disabilities has been awarded to Vasanthi Jayaraman, PhD, of UTHealth Houston by the National Institutes of Health.

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Researchers have discovered a specific genetic variant in SCN1A, the most common genetic epilepsy, that leads to an earlier onset of epilepsy, with clinical features distinct from other epilepsies. The researchers also identified a potentially effective treatment strategy.

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À l’automne 2021, la section des soins infirmiers de l’ILAE a été créée pour créer un « foyer » pour les infirmières du monde entier qui s’occupent de personnes atteintes d’épilepsie.

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En el otoño de 2021, se formó la Sección de Enfermería de ILAE para crear un "hogar" para las enfermeras de todo el mundo que atienden a personas con epilepsia.

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Epilepsy is a neurological disorder in which brain activity becomes abnormal, causing seizures or periods of unusual behavior, sensations, and sometimes loss of awareness. Anyone can develop epilepsy, and it affects both males and females of all races, ethnic backgrounds and ages.

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A benzodiazepine is the first-line treatment of choice for status epilepticus. Despite guidelines from 2012 and 2016 thta recommend medication types, doses, and means of administration, benzodiazepines are often underdosed, or not given at all.

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Nurses who care for people with epilepsy fulfill dozens of roles, helping people to navigate clinical, educational, emotional, and social dimensions of epilepsy. But the depth, breadth, and impact of these roles is not always recognized.

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A small group of brain cells linked in a circuit is responsible for setting off whole-brain seizures in a rare form of epilepsy affected by blood sugar levels, a study led by UT Southwestern researchers suggests. The finding, published in Science Translational Medicine, could lead to new treatments for other metabolic disorders in the brain, the authors said.

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People who have a COVID-19 infection are more likely to develop seizures or epilepsy within the next six months than people who have an influenza infection, according to a study published in the November 16, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology.

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Los neurólogos de todo el mundo tienen preocupaciones sobre el uso de medicamentos genéricos anticrisis, cuestionando la calidad deficiente o inconsistente, el acceso limitado, el costo y la falta de control regulatorio.

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La mayor parte de las investigaciones sobre el estado epiléptico se ha realizado en países de altos recursos. Es probable que los países de bajos recursos mantengan una incidencia más alta de estados epilépticos, debido a las mayores brechas en el tratamiento de la epilepsia.

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Until recently, no international organization existed to unite the millions of nurses who care for people with epilepsy. Now, the ILAE Nursing Section is addressing issues of education, value, and responsibilities, with the goal of improving epilepsy care worldwide.

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A recent study reported data from more than 1,300 infants whose mothers are enrolled in the Kerala Registry of Epilepsy in Pregnancy. Babies were evaluated for mental and motor development at 1 year of age.

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Alzheimer's disease is a risk factor for epilepsy - and epilepsy is a risk factor for Alzheimer's. We spoke with Dr. Andrew Cole and Dr. Alice Lam about the latest research and some intriguing findings that suggest links between these two conditions.

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From medical training during a civil war to starting Kentucky's first epilepsy fellowship program, Dr. Meriem Bensalem-Owen talks with Sharp Waves about her career journey.

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New research will aim to identify the electrical activity occurring as the brain receives information and then test whether targeted, gentle electrical stimulation can strengthen a specific memory.

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University of Minnesota Twin Cities researchers are leading a comprehensive global clinical study that seeks to reveal the functional effects of vagus nerve stimulation (VNS) across the human body.

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Higher exposure to a certain type of traffic-related air pollution called particulate matter may be linked to an increased risk of dementia, according to a meta-analysis published in the October 26, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology. Researchers specifically looked at fine particulate matter, PM2.5, which consists of pollutant particles of less than 2.5 microns in diameter suspended in air. The meta-analysis included all available studies on air pollution and risk of dementia.

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For a long time, functional, nonepileptic seizures were not believed to involve structural changes in the brain, but a new study suggests that they are associated with structural changes that can be seen using MRI. Researchers say the findings bring potential for earlier diagnosis of functional seizures, which are often misdiagnosed as epilepsy.

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As the American Neurological Association’s 147th Annual Meeting wraps up today, October 25, the ANA is holding a Media Roundtable at 11 a.m. U.S. Central for reporters to access the latest developments in neurology and neuroscience.

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The American Neurological Association (ANA), the professional organization representing the world’s leading academic neurologists and neuroscientists, has appointed Brenda Orffer, CAE, as its new Chief Executive Officer and Nadine Goldberg, PhD, MS, as Chief Program Officer.

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A female adult patient with idiopathic generalized epilepsy (IGE) is now the first to receive neuromodular stimulation of the brain to see if it can help with seizures.

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Even months after critical illness for sepsis, children are at risk for new or worsening medical conditions, a study suggests.

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What is autoimmune-associated epilepsy, and how is it different from acute seizures with an autoimmune cause? How can clinicians best diagnose and treat these conditions? Sharp Waves reporter Dr. Maryam Nabavi-Nouri spoke with Dr. Claude Steriade.

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People who have had bariatric surgery may have an increased risk of developing epilepsy, according to a study published in the September 28, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology.

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SNOMED International and the International League Against Epilepsy (ILAE) have signed a five-year agreement that will contribute to global improvements in care and services for people with epilepsy.

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Researchers found that across nearly 50,000 visits, patients continued to use telemedicine effectively even with the reopening of outpatient clinics a year after the onset of the COVID-19 pandemic. However, prominent barriers for socially vulnerable families and racial and ethnic minorities persist, suggesting more work is required to reach a wider population with telemedicine.

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Does COVID-19 infection affect people with epilepsy differently? Are people with epilepsy less likely to get vaccinated? A session at the European Epilepsy Congress in July 2022 covered these topics, and more.

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Calorie restriction has long been associated with reduced seizures in epilepsy.

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Wiley and ILAE launched the Epilepsy Knowledge Hub to provide health care professionals with the latest research and guidelines to aid in diagnosis, classification, and treatment for people with epilepsy syndromes.

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We spoke with two authors of a study that attempted to tally all the cases of newly diagnosed epilepsy and first seizures during a single year in County Cork, Ireland. They wanted to know: In this relatively homogenous county, were there higher rates of epilepsy in more socially deprived neighborhoods?