Celiac disease patients who experience chronic damage in the small intestine may be more likely to break a hip than those whose intestinal tissues have begun healing, according to new research accepted for publication in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM).
Scientists from the Florida campus of The Scripps Research Institute have identified a normally small subset of immune cells that may play a major role in the development of Crohn’s disease generally and in disease-associated steroid resistance specifically.
Researchers at the UNC School of Medicine found that two on-the-rise esophagus conditions are so similar that even a biopsy is not enough to distinguish one disease from the other.
People who have diverticulosis, or pouches in the lining of the colon, often worry that they will eventually develop a painful and sometimes serious condition called diverticulitis, as previous research has shown that one in four, or up to 25 percent, of those with the condition will.
Attracted by the decadent treats, fried meats, and festive cocktails of the Thanksgiving-to-New-Year feast, heartburn can be an unwelcome guest during the holidays.
Scientists at the Institute for Genome Sciences at the University of Maryland School of Medicine and doctors at Sinai Hospital of Baltimore have found that restoring the normal, helpful bacteria of the gut and intestines may treat patients suffering from recurrent Clostridium difficile infections.
A study led by Nancy Bergstrom, Ph.D., associate dean at The University of Texas Health Science Center at Houston (UTHealth) School of Nursing, found that nursing homes that utilize high-density foam mattresses may not need to turn residents every two hours to prevent pressure ulcers, a practice that has been used for over 50 years.
Patients with non-celiac wheat sensitivity (NCWS) and other food sensitivities showed clinical, laboratory and histological characteristics suggesting they may be suffering from a non-IgE-mediated food allergy, according to the article, “Non-Celiac Wheat Sensitivity as an Allergic Condition: Personal Experience and Narrative Review,” published online today in The American Journal of Gastroenterology.
Humans maintain a symbiotic relationship with the trillions of beneficial microbes that colonize their bodies. Inflammatory bowel disease is one of the best-studied diseases associated with alterations in the composition of beneficial bacterial populations. Researchers have identified that the enzyme HDAC3 –important in epigenetics -- is a key mediator in maintaining proper intestinal integrity and function in the presence of friendly bacteria.
An international team led by University of Adelaide researchers has identified the mechanism of pain relief of a new drug for treating Irritable Bowel Syndrome with Constipation (IBS-C), based on nonclinical studies, and quantified its effectiveness in pain relief in human trials.
For the first time, a simple blood test may be the best way to determine if a patient is suffering from Irritable Bowel Syndrome (IBS), or another serious condition such as Inflammatory Bowel Disease (IBD,) according to Cedars-Sinai physician researcher Mark Pimentel, MD, lead author of a multicenter clinical trial.
Have you ever wondered why young children can eat bags of Halloween candy and feel fine the next day – compared to adults who experience all sorts of agony following the same junk food binge? Evolution and a gene called Foxo may be to blame.
More than 4,000 gastroenterologists, physicians and other health care professionals from around the world will convene this week for the American College of Gastroenterology's (ACG) 78th Annual Scientific Meeting at the San Diego Convention Center in San Diego, CA, to review and present the latest scientific advances in gastrointestinal research, treatment of digestive diseases and clinical practice management.
Physical activity is associated with a reduced risk of esophageal cancer, particularly esophageal adenocarcinoma, according to a new meta-analysis of published observational studies presented by Mayo Clinic researcher Siddharth Singh, M.D., at the American College of Gastroenterology’s 78th Annual Scientific Meeting in San Diego, CA.
Fecal microbiota transplantation (FMT) is effective in resolving Clostridium difficile infection (CDI) in immunocompromised patients with few serious adverse events according to an retrospective series presented at the 78th Annual Scientific Meeting of the American College of Gastroenterology. Two other studies looked at FMT in Inflammatory Bowel Disease (IBD) patients who also suffered from C. difficile infection, as well as the impact of altering gut flora with transplant of fecal bacteria upon symptoms of Irritable Bowel Syndrome.
A smartphone virtual coach application for colonoscopy preparation is shown to be easy to use and engaging, even among people who have previously undergone colonoscopy. Results of a usability study were presented at the American College of Gastroenterology’s 78th Annual Scientific Meeting in San Diego, CA.
Two separate studies presented at the American College of Gastroenterology’s 78th Annual Scientific Meeting in San Diego analyze inflammatory bowel disease (IBD) health outcomes in the United States and Canada. IBD, which includes both Crohn’s disease and ulcerative colitis, is a chronic inflammatory condition of the intestinal tract and is estimated to affect over 1.4 million people in the U.S.
Severe liver damage, and even failure, has been associated with the consumption of weight loss supplements, an herbal supplement and an energy drink, according to four separate case reports presented at the American College of Gastroenterology’s 78th Annual Scientific Meeting in San Diego, CA. Use of herbal and dietary supplements is widespread for a variety of health problems. Because many patients do not disclose supplement use to their physicians, important drug side effects can be missed.
Childhood and infancy factors have been linked to a predisposition to developing Clostridium difficile (C. difficile) infection, the leading cause of health-care associated diarrhea, according to new research being presented at the American College of Gastroenterology’s 78th Annual Scientific Meeting in San Diego, CA.
A blood-test could easily determine whether a patient is suffering from Irritable Bowel Syndrome (IBS), eliminating the need for extensive and expensive dialogistic testing in order to rule out more serious conditions like Inflammatory Bowel Disease (IBD), suggests Mark Pimentel, M.D., lead author of a multicenter study unveiled today at the American College of Gastroenterology’s 78th Annual Scientific Meeting in San Diego, CA.
Patients with inflammatory bowel disease are at an increased risk of stroke and heart attack according to a new study presented by Mayo Clinic researchers at the American College of Gastroenterology’s Annual Scientific Meeting, Oct. 11–16, in San Diego.
New research has shown that the stomach naturally produces more stem cells than previously realized, likely for repair of injuries from infections, digestive fluids and the foods we eat.
"Pouchitis" developing after surgery for ulcerative colitis (UC) is associated with changes in gene expression, which increase along with disease severity, reports a study in Inflammatory Bowel Diseases, official journal of the Crohn's & Colitis Foundation of America (CCFA). The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
University of Adelaide researchers have made advances in the understanding of one of the world's most common medical conditions, gastric reflux, and how patients experience pain from it.
A Mayo Clinic researcher, along with his collaborators, has shown that an individual’s genomic makeup and diet interact to determine which microbes exist and how they act in the host intestine. The study was modeled in germ-free knockout mice to mimic a genetic condition that affects 1 in 5 humans and increases the risk for digestive diseases.
UCLA researchers have described a new form of irritable bowel syndrome (IBS) that occurs after an acute bout of diverticulitis, a finding that may help lead to better management of symptoms and relief for patients.
A statistical model accounting for dozens of different genes in combination—and the interactions between them—is an important step forward in understanding the genetic factors affecting the risk of Crohn's disease (CD), reports a study in Inflammatory Bowel Diseases, official journal of the Crohn's & Colitis Foundation of America (CCFA). The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
Vedolizumab, a new intravenous antibody medication, has shown positive results for treating both Crohn’s disease and ulcerative colitis, according to researchers at the University of California San Diego, School of Medicine. The findings, published in two papers, will appear in the August 22 issue of the New England Journal of Medicine (NEJM).
Researchers have identified a new genome-wide significant locus (the place a gene occupies on a chromosome) for infantile hypertrophic pyloric stenosis (IHPS), a serious gastrointestinal condition associated with gastrointestinal obstruction, according to a study in the August 21 issue of JAMA. Characteristics of this locus also suggest the possibility of an inverse relationship between levels of circulating cholesterol in neonates and IHPS risk.
Swiss researchers report an increase risk of inflammatory bowel disease (IBD) relapse in patients during heat wave periods. The study published in The American Journal of Gastroenterology also found an increase of infectious gastroenteritis during heat waves, with the strongest impact following a 7 day lag time after the heat wave.
Call it therapeutic poop, if you will, but the best hope yet for an effective treatment of childhood infections with the drug-resistant bacterium C. difficile may come straight from the gut, according to recent research. This is why pediatric gastroenterologists at the Johns Hopkins Children’s Center are launching a fecal transplantation program for patients with recurrent diarrhea caused by what they say is a wily pathogen that is increasingly impervious to drugs and a rapidly growing problem among children and adults. Over the last 20 years, cases of antibiotic-associated diarrhea have more than doubled, with nearly three million new infections each year, with up to a fourth of patients not responding to antibiotics, research shows. Most such cases, the researchers say, stemmed from infections with C. difficile.
New treatment guidelines on the diagnosis and management of achalasia, a primary motor disorder of the esophagus, appear in the August issue of The American Journal of Gastroenterology.
Chances are you see pills, powders, drinks and yogurt infused with probiotics every time you go to the grocery store. Dr. Eamonn Quigley, an expert in gut health, heads the gastroenterology and hepatology division at Houston Methodist Hospital. Here he addresses 5 common claims about probiotics.
Physicians at Johns Hopkins say they are encouraged by early results in three patients of their new treatment for gastroparesis, a condition marked by the failure of the stomach to properly empty its contents into the small intestine. In an article published online today in the journal Endoscopy, they describe how the placement of a small metal stent in the stomach can improve life for people who suffer from severe bouts of nausea, abdominal pain and vomiting that accompany the condition.
A procedure to treat acid reflux could help prevent chronic rejection in lung transplant patients, according to a study published in the Journal of the American College of Surgeons.
Better treatments for people suffering from compromised intestinal immunity may emerge from a small-animal model of human intestinal immune development.
Cancer of the esophagus is beginning to level off in the United States, but one type of esophageal cancer remains a serious threat to African-American men, especially if they drink and smoke.
Significant improvement in hardest-to-treat chronic constipation shown in novel use of electrical stimulation (neurostimulation) at home.
Did you know the number one reason children complain about chest pain is because they actually have heartburn? A lot of people believe that adults are the only ones who get it, but more and more children complain about heartburn, which often creates an uncomfortable burning feeling behind the breastbone. It has nothing to do with your heart, but everything to do with your stomach and esophagus. These days there are plenty of children who like to eat spicy foods. From hot sauce to salsa to ‘hot chips’ and ‘hot popcorn’, these types of foods are included in the diets of many of the children that I see who complain of Gastroesophageal Reflux Disease (GERD) or heartburn. There are plenty of other foods however that I think parents might be surprised to realize that they can trigger it.
• Frequent history of heartburn elevated risk for throat and vocal cord cancers. • Use of antacids lowered risk. • Further studies are needed to confirm the protective effect of antacids.
The human gut is loaded with helpful bacteria microbes, yet the immune system seemingly turns a blind eye. Now, researchers know how this friendly truce is kept intact. Innate lymphoid cells directly limit the response by inflammatory T cells to commensal bacteria in the gut of mice. Loss of this ILC function effectively puts the immune system on an extended war footing against the commensal bacteria a condition observed in multiple chronic inflammatory diseases.
Nearly three out of four pregnant women experience constipation, diarrhea or other bowel disorders during their pregnancies, a Loyola University Medical Center study has found.
Patients with inflammatory bowel disease (IBD) are at higher risk of melanoma, a form of skin cancer, report researchers at Mayo Clinic.
Two genome-wide association studies and a subsequent meta-analysis have found that certain genetic variations are associated with susceptibility to Helicobacter pylori, a bacteria that is a major cause of gastritis and stomach ulcers and is linked to stomach cancer, findings that may help explain some of the observed variation in individual risk for H pylori infection.
A new procedure involving a magnetic ring of beads that fits around your pinky has been shown to stop GERD in people whose medication stopped working.
There has been a lot of buzz about the weight loss benefits of eating gluten-free, but UAB doctors say it’s important to find out if you need to eat this way or not.
Every five years, the Crohn's & Colitis Foundation of America (CCFA) gathers top researchers in inflammatory bowel disease (IBD) to set the research agenda for the next five years. The findings and recommendations of these expert workgroups are presented in a series of detailed "Challenges in IBD Research" reports, now available in Inflammatory Bowel Diseases, official journal of the CCFA. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
Stress has a way of significantly altering the composition of gut bacteria, which leads to inflammation and often times, belly pain for those with irritable bowel syndrome. But a University of Michigan Health System study shows how probiotics can reverse the effect of stress.
Researchers at Wake Forest Baptist Medical Center and colleagues have identified a special population of adult stem cells in bone marrow that have the natural ability to migrate to the intestine and produce intestinal cells, suggesting their potential to restore healthy tissue in patients with inflammatory bowel disease (IBD).
RSS
Medicine keyboard_arrow_right
Sciencekeyboard_arrow_right
Life keyboard_arrow_right
Business keyboard_arrow_right
Journal News keyboard_arrow_right
By Location keyboard_arrow_right
Meetings, Grants, and Events keyboard_arrow_right