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Medicine

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Malaria, Prenatal, Children

Researchers Discover Key to Malaria Susceptibility in Children

A team of researchers from Case Western Reserve University School of Medicine have solved the mystery of why some children are more susceptible to malaria infection and anemia. These novel findings suggest that some children who are exposed to Plasmodium falciparum (P. falciparum) malaria before birth become tolerant to the malaria parasites, or their soluble products.

Medicine

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Lyme Disease, Alabama, Satellites, NASA

Using Satellites to Study Lyme Disease

Six University of Alabama at Birmingham (UAB) students and two students from other universities are using satellite imagery to identify possible habitats in Alabama for the black-legged tick that carries and transmits Lyme disease.

Medicine

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HIV/AIDS, African Americans, Peer Education, Health Disparity

Young People at High HIV Risk Say Peers Should Teach Prevention

African-American adolescents have some of the highest rates of HIV infection in the United States, and efforts to educate them about preventing the disease must include the help of their adolescent peers, new research suggests.

Medicine

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Hepatitis, Infectious, Disease, HEP, Peginterferon, Alfa 2 B, Ribavirin

Hepatitis C Infection: Treatment Options Equally Effective, Likelihood of Success Known Early On

Results of a long-awaited study of 3,070 American adults at Johns Hopkins and 118 other U.S. medical centers show that treatment with either of the two standard antiviral drug therapies is safe and offers the best way for people infected with hepatitis C to prevent liver scarring, organ failure and death.

Medicine

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Mycobacterium, Tuberculosis, Infectiouis, Disease, Vaccines

Animal TB "Tracker" to Speed Drug and Vaccine Studies

TBTracker.jpg

Johns Hopkins researchers have developed a novel way to monitor in real time the behavior of the TB bacterium in mouse lungs noninvasively pinpointing the exact location of Mycobacterium tuberculosis. The new monitoring system is expected to speed up what is currently a slow and cumbersome process to test the safety and efficacy of various TB drug regimens and vaccines in animals. Plans are already under way for developing a similar system to monitor TB disease in humans.

Medicine

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cell, Receptor, car, CVB, Coxsackievirus, Infectious, Disease, Myocarditis

Eliminating Cell Receptor Prevents Infection in Animal Study

New research from The Children's Hospital of Philadelphia sheds light on the role of cell receptors in acting as gatekeepers for infectious viruses. By using mice genetically engineered to lack a particular receptor in heart and pancreas cells, the study team prevented infection by a common virus (Group B coxsackievirus) that causes potentially serious diseases in humans.

Medicine

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HIV, AIDS, Pmtct, Breasfeeding, Hiv Prevention, Malawi, Randomized Trial

Giving Antiretroviral Drugs to Infants Or Mothers Reduces Transmission of HIV Through Breast Milk

Giving daily antiretroviral syrup to breastfeeding infants or treating their HIV-infected mothers with highly active antiretroviral drugs is safe and effective in preventing mother-to-child HIV transmission through breast milk, a study led by University of North Carolina at Chapel Hill investigators has found.

Science

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Vaccine, Malaria, Mosquito, Transmission Blocking, Protein, Johns Hopkins Malaria Research Institute

Vaccine Blocks Malaria Transmission in Lab Experiments

Researchers at the Johns Hopkins Malaria Research Institute have for the first time produced a malarial protein (Pfs48/45) in the proper conformation and quantity to generate a significant immune response in mice and non-human primates for use in a potential transmission-blocking vaccine. Antibodies induced by Pfs48/45 protein vaccine effectively blocked the sexual development of the malaria-causing parasite, Plasmodium, as it grows within the mosquito.

Medicine

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Medical Grade Honey, Topical, Wound, MRSA, VRS, Leptospermum Honey, Antimicrobial, Immune Modulatory, Scar Reduction, Multi Drug Resistance, Medihoney, Dsci, Derma Sciences, Diabetic Foot Ulcers, Venous Stasis Leg Ulcers, Arterial Leg Ulcers, Leg Ulcers O

New Paper Highlights Antimicrobial Effectiveness Of Medical-Grade Honey In Topical Wound Care

With MRSA and VRS seriously compromising treatment options, dressing wounds with honey provides an alternative, according to a recent paper published in the European Journal of Clinical Microbiological Infectious Diseases.

Medicine

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HIV, Transmission, Infection, Saliva, Blood

Pre-chewed Food Could Transmit HIV

Researchers have uncovered the first cases in which HIV almost certainly was transmitted from mothers other caregivers to children through pre-chewed food.







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