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Medicine

Science

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Cancer, Metastases, Metastasis, Stage 1-4, Cancer Staging, Biology, Health, Science, San Diego, stem

At Last, a Clue to Where Cancer Metastases Are Born

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Scientists at The Scripps Research Institute (TSRI) have discovered why some cancers may reoccur after years in remission.

Medicine

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Stem Cells, Inner Ear, Inner Ear Balance Disorders, Ear And Hearing, Organoids

Researchers Create Human Inner Ear Organs That Could Lead To New Therapies For Hearing, Balance Impairments

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Researchers at Indiana University School of Medicine have successfully developed a method to grow inner ear tissue from human stem cells—a finding that could lead to new platforms to model disease and new therapies for the treatment of hearing and balance disorders.

Medicine

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Retinal Diseases, Stem Cells, retinal progenitor cells, FDA, Regenerative Medicine Advanced Therapy, Cirm, clinical trial, Blindness, Retinitis Pigmentosa

jCyte Receives Regenerative Medicine Advanced Therapy Designation

Cell therapy company jCyte has received Regenerative Medicine Advanced Therapy designation from the FDA for their developmental retinitis pigmentosa therapy.

Medicine

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Ovarian Cancer, Female Cancer, Gynecologic Cancer, gynecologic cancer research, Cancer Treatment, Combination Therapy, Tumors, ovarian cancer research, Stem Cell

Combination Therapy Could Provide New Treatment Option for Ovarian Cancer

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UCLA study identifies a potential test that may help select patients for whom combination therapy could be most effective

Medicine

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Bipolar Disorder, Manic Depressive Illness, Stem Cell, psychiatric conditions, Mental Health

Auto Pioneer’s Family Helps U-M Turn Tragedy Into Discovery with Promise to Match Donations Up to $5M

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A new $5 million challenge gift aims to boost scientific research on bipolar disorder, while honoring the legacy of an automotive pioneer who battled the condition during his life.

Medicine

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Linda Resar, Linda M. S. Resar, Stem Cells, Intestinal, Niche, Transgenic, HGMA1, Cancer, colon

Single Gene Encourages Growth of Intestinal Stem Cells, Supporting "Niche" Cells--and Cancer

A gene previously identified as critical for tumor growth in many human cancers also maintains intestinal stem cells and encourages the growth of cells that support them, according to results of a study led by Johns Hopkins researchers. The finding, reported in the Apr. 28 issue of Nature Communications, adds to evidence for the intimate link between stem cells and cancer, and advances prospects for regenerative medicine and cancer treatments.

Medicine

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arthritis, , Induced Pluripotent Stem Cells, Tnf Alpha, Inflammation, Rheumatoid Arthris

Stem Cells Edited to Fight Arthritis

Using CRISPR technology, a team of researchers led by Farshid Guilak, PhD, at Washington University School of Medicine in St. Louis, rewired stem cells' genetic circuits to produce an anti-inflammatory arthritis drug when the cells encounter inflammation. The technique eventually could act as a vaccine for arthritis and other chronic conditions.

Medicine

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Muscle Regeneration, Muscle Repair, Aging, Sarcopenia, Muscle Loss, Duchenne Muscular Dystrophy

New Insights on Triggering Muscle Formation

A team of scientists led by Lorenzo Puri, M.D., Ph.D., has identified a previously unrecognized step in stem cell-mediated muscle regeneration. The study, published in Genes and Development, helps explain why muscle stem cells lose the ability to generate new muscle as they age and provides insight into accelerated muscle stem cell aging in muscular dystrophy.

Medicine

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Stem Cells, Epigenetic, Metabolism, Biology, Medicine, Cancer, Genome

Einstein’s 2017 Stem Cell Symposium Spotlights Epigenetics and Metabolism

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On Monday, April 24, the Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research at Albert Einstein College of Medicine will host its third Stem Cell Symposium, focusing on the importance of cell metabolism and epigenetics. Leading scientists from the U.S., Japan and Germany will present their latest research and describe the hurdles to translating new finding into therapeutics.

Science

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Neurobiolgy, Axons, Biology, Stem Cells, Neuroscience, nervous system circuits, Nervous System, Neuron, Axon Guidance, Neural Progenitor Cells, Nerve Regeneration, Nerve Regrowth, stem cells and diabetes, Netrin 1, netrin-1

Study Overturns Seminal Research About the Developing Nervous System

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New research by scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA overturns a long-standing paradigm about how axons grow during embryonic development. The findings of the study, led by Samantha Butler, associate professor of neurobiology, could help scientists replicate or control the way axons grow, which may be applicable for diseases that affect the nervous system, such as diabetes, as well as injuries that sever nerves.







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